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Mise ŕ jour le : 20-09-2017




Les derniers abstracts de la revue Gastrointestinal Endoscopy :


    Date de mise en ligne : Samedi 16 septembre 2017
    Amrit K. Kamboj, Prasuna Muppa, Liam Zakko, Kenneth K. Wang, Cadman L. Leggett
    Use of Volumetric Laser Endomicroscopy to Characterize a Duodenal Neuroendocrine Tumor


    Date de mise en ligne : Samedi 16 septembre 2017
    Kavel Visrodia, Liam Zakko, Theresa Nolte, Kenneth K. Wang
    A novel method to prevent catheter dysfunction during spray cryotherapy


    Date de mise en ligne : Samedi 16 septembre 2017
    Ihab I. El Hajj, Mark A. Gromski, Glen A. Lehman, Jeffrey J. Easler, Stuart Sherman
    Accidental fracture of an EUS-FNA needle


    Date de mise en ligne : Vendredi 08 septembre 2017
    Kenneth Barshop, Field F. Willingham, William R. Brugge, Lawrence R. Zukerberg, Braden Kuo
    Endoscopic Mucosal Resection is Superior to Rectal Suction Biopsy for Analysis of Enteric Ganglia in Constipation and Dysmotility
    Patients with chronic constipation or motility disorders may be referred for rectal suction biopsy (RSB) to rule out Hirschsprung’s disease (HD). RSB may not be successful beyond infancy due to the increased thickness of rectal mucosa. Endoscopic mucosal resection (EMR) could improve the diagnostic yield for HD when compared with traditional RSB because of the larger and deeper samples acquired for analysis.


    Date de mise en ligne : Jeudi 07 septembre 2017
    Osamu Goto, Masayuki Shimoda, Motoki Sasaki, Yoshiyuki Kiguchi, Yutaka Mitsunaga, Teppei Akimoto, Yasutoshi Ochiai, Ai Fujimoto, Tadateru Maehata, Toshihiro Nishizawa, Hiroya Takeuchi, Yuko Kitagawa, Kaori Kameyama, Naohisa Yahagi
    Potential for peritoneal cancer cell seeding in endoscopic full-thickness resection for early gastric cancer
    During endoscopic full-thickness resection (EFTR) for cancers, whether exposure of the lumen to the abdominal cavity during the procedure is acceptable is controversial because of the potential risk of tumor cell seeding. To assess the possibility of transplantation due to contact with tumor cells during the procedure, we prospectively investigated the ability of cancer cells to be detached by touching the tumor surface.


    Date de mise en ligne : Mardi 05 septembre 2017
    Elizabeth A. Scoville, David A. Schwartz
    Endoscopy in inflammatory bowel disease: advances in disease management


    Date de mise en ligne : Lundi 04 septembre 2017
    Mohamed M. Abdelfatah, Ian S. Grimm, Lisa M. Gangarosa, Todd H. Baron
    Cohort study comparing the diagnostic yields of 2 different EUS fine-needle biopsy needles
    Two second-generation, flexible EUS fine-needle biopsy (FNB) needles have recently been marketed in the United States. Thus far, there have been no comparative studies of the diagnostic yield of these needles. The aim of this study was to compare the diagnostic yield achieved with FNB using one needle during one time period and the other needle during a second time period.


    Date de mise en ligne : Lundi 04 septembre 2017
    Anna M. Duloy, Tonya R. Kaltenbach, Rajesh N. Keswani
    Assessing Colon Polypectomy Competency and its Association with Established Quality Metrics
    Inadequate polypectomy leads to incomplete resection, interval colorectal cancer, and adverse events. However, polypectomy competency is rarely reported and quality metrics are lacking. The primary aims of this study were to (1) assess polypectomy competency among a cohort of gastroenterologists, and (2) measure the correlation between polypectomy competency and established colonoscopy quality metrics (adenoma detection rate [ADR] and withdrawal time [WT]).


    Date de mise en ligne : Lundi 04 septembre 2017
    Ben Parker, James Buchanan, Sarah Wordsworth, Satish Keshav, Bruce George, James E. East
    Managing ulcerative colitis patients with endoscopically invisible low-grade dysplasia
    There is uncertainty regarding the optimal management of endoscopically invisible (“flat”) low grade dysplasia in ulcerative colitis. Such a finding does not currently provide an automatic indication for colectomy; however, a recommendation of surveillance instead of surgery is controversial. The aim of this study was to determine the clinical and cost-effectiveness of colonoscopic surveillance versus colectomy for endoscopically invisible low-grade dysplasia of the colon in ulcerative colitis.


    Date de mise en ligne : Lundi 04 septembre 2017
    Min Kyung Jeon, Hoonsub So, Jooryung Huh, Hee Sang Hwang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Don Choi, Byong Duk Ye, Seung-Jae Myung, Suk-Kyun Yang, Jeong-Sik Byeon
    Endoscopic Features and Clinical Outcomes of Colorectal Mucosa-associated Lymphoid Tissue Lymphoma
    Colorectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease. The purpose of this study was to investigate the clinical and endoscopic features of colorectal MALT lymphoma.


    Date de mise en ligne : Vendredi 01 septembre 2017
    Fateh Bazerbachi, Tarek Sawas, Eric J. Vargas, Larry J. Prokop, Suresh T. Chari, Ferga C. Gleeson, Michael J. Levy, John Martin, Bret T. Petersen, Randall K. Pearson, Mark D. Topazian, Santhi S. Vege, Barham K. Abu Dayyeh
    Metal Stents Versus Plastic Stents for the Management of Pancreatic Walled-Off Necrosis: A Systematic Review and Meta-Analysis
    Endoscopic transluminal drainage of symptomatic walled-off necrosis (WON) is a good management option, although the optimal choice of drainage site stent is unclear. We performed a systematic review and meta-analysis to compare metal stents (MSs) and plastic stents (PSs) in terms of WON resolution, likelihood of resolution after one procedure, and adverse events.


    Date de mise en ligne : Vendredi 01 septembre 2017
    Sunguk Jang, Tyler Stevens, Mansour Parsi, Rocio Lopez, Gregory Zuccaro, John Dumot, John J. Vargo
    Association of covered metallic stents with cholecystitis and stent migration in malignant biliary stricture
    ERCP with self-expandable metallic stent (SEMS) placement provides reliable and durable relief of malignant biliary obstruction. Our objective was to compare efficacy and adverse outcomes between uncovered SEMSs (USEMSs) and covered SEMSs (CSEMSs).


    Date de mise en ligne : Mercredi 30 aoűt 2017
    Ateev Mehrotra, Michele Morris, Rebecca A. Gourevitch, David S. Carrell, Daniel A. Leffler, Sherri Rose, Julia B. Greer, Seth D. Crockett, Andrew Baer, Robert E. Schoen
    Physician Characteristics Associated with Higher Adenoma Detection Rate
    Patients who receive a colonoscopy from a physician with a low adenoma detection rate are at higher risk of subsequent colorectal cancer. It is unclear what drives the variation across physicians in adenoma detection rate. We describe physician characteristics associated with higher ADR.


    Date de mise en ligne : Mercredi 30 aoűt 2017
    James Buxbaum, Ara Sahakian, Christopher Ko, Preeth Jayaram, Christianne Lane, Chung Yao Yu, Ravi Kankotia, Loren Laine
    Randomized trial of cholangioscopy-guided laser lithotripsy versus conventional therapy for large bile duct stones (with videos)
    Bile duct stones >1 cm have a decreased incidence of successful endoscopic extraction and often require lithotripsy. Although prior guidelines suggested mechanical lithotripsy for large CBD stones, current guidelines suggest cholangioscopy-guided lithotripsy as an adjunct with or without balloon dilation or mechanical lithotripsy. However, no randomized trials have assessed the utility of this practice.


    Date de mise en ligne : Lundi 28 aoűt 2017
    Michael Scaffidi, Samir C. Grover, Heather Carnahan, Jeffrey J. Yu, Elaine Yong, Geoffrey C. Nguyen, Simon C. Ling, Nitin Khanna, Catharine M. Walsh
    A Prospective Comparison of Live and Video-Based Assessments of Colonoscopy Performance
    Colonoscopy performance is typically assessed by a supervisor in the clinical setting. There are limitations of this approach, however, as it allows for rater bias and increases supervisor workload demand during the procedure. Video-based assessment of recorded procedures has been proposed as a complementary means by which to assess colonoscopy performance. This study sought to investigate the reliability, validity and feasibility of video-based assessments of competence in performing colonoscopy, compared with live assessment.


    Date de mise en ligne : Lundi 28 aoűt 2017
    Laurie B. Grossberg, Alina Vodonos, Konstantinos Papamichael, Victor Novack, Mandeep Sawhney, Daniel A. Leffler
    Predictors of post-colonoscopy emergency department use
    Unplanned hospital visits within 7 days of colonoscopy was recently proposed as a quality measure. It is unknown if patient, procedure, or endoscopist characteristics predict post-colonoscopy emergency department (ED) visits. Our aim was to determine the incidence and relatedness of ED visits within 7 days of colonoscopy, and to identify predictors of post-colonoscopy ED use.


    Date de mise en ligne : Jeudi 24 aoűt 2017
    Monica Saumoy, Yecheskel Schneider, Xi Kathy Zhou, Alpana Shukla, Michel Kahaleh, Louis Aronne, Reem Z. Sharaiha
    A Single-Operator Learning Curve Analysis for the Endoscopic Sleeve Gastroplasty
    Endoscopic sleeve gastroplasty (ESG) is a novel, incisionless technique for gastric volume reduction to promote weight loss. Our aim was to describe the learning curve for performing ESG using a prospective case series.


    Date de mise en ligne : Jeudi 24 aoűt 2017
    Naoki Ishii, Fumio Omata, Naoyoshi Nagata, Mitsuru Kasise
    Effectiveness of endoscopic treatments for colonic diverticular bleeding
    Several endoscopic modalities have been used for the treatment of colonic diverticular bleeding (CDB). The aim of this study was to evaluate the effectiveness of endoscopic treatment for CDB.


    Date de mise en ligne : Mercredi 23 aoűt 2017
    Djuna L. Cahen, Schalk W. van der Merwe, Wim Laleman, Jan-Werner Poley, Marco J. Bruno
    A biodegradable noncovered self-expandable stent to treat pancreatic duct strictures in chronic pancreatitis; a proof of principle
    In chronic pancreatitis (CP), fibrotic pancreatic duct (PD) strictures pose a therapeutic challenge, as endoscopic dilatation requires multiple procedures, with suboptimal results. Biodegradable self-expandable stents (BD-SESs) may serve as an alternative in this setting.


    Date de mise en ligne : Mercredi 23 aoűt 2017
    Takayoshi Tsuchiya, Anthony Yuen Bun Teoh, Takao Itoi, Kenji Yamao, Kazuo Hara, Yousuke Nakai, Hiroyuki Isayama, Masayuki Kitano
    Long-term outcome of EUS-guided choledochoduodenostomy using a lumen-apposing metal stent for malignant distal biliary obstruction: a prospective multicenter study
    EUS-guided choledochoduodenostomy (EUS-CDS) using conventional tubular stents has been successfully performed. However, EUS-CDS carries a high risk of bile leakage with attendant adverse events. This study aimed to prospectively evaluate the long-term outcome of EUS-CDS using a dedicated lumen-apposing metal stent (LAMS).


    Date de mise en ligne : Mercredi 23 aoűt 2017
    Kotaro Shibagaki, Norihisa Ishimura, Naoki Oshima, Tsuyoshi Mishiro, Nobuhiko Fukuba, Yuji Tamagawa, Noritsugu Yamashita, Hironobu Mikami, Daisuke Izumi, Hideaki Taniguchi, Shuichi Sato, Shunji Ishihara, Yoshikazu Kinoshita
    Esophageal triamcinolone acetonide-filling method: a novel procedure to prevent stenosis after extensive esophageal endoscopic submucosal dissection (with videos)
    Endoscopic submucosal dissection (ESD) for extensive esophageal carcinomas may cause severe stenosis requiring endoscopic balloon dilations (EBD). A standard preventing method has not been established. We propose the esophageal triamcinolone acetonide (TA)-filling method as a novel local-steroid administration procedure.


    Date de mise en ligne : Mercredi 23 aoűt 2017
    Ara B. Sahakian, Preeth Jayaram, M. Victoria Marx, Kazuhide Matsushima, Caroline Park, James L. Buxbaum
    Metallic coil and N-butyl-2-cyanoacrylate for closure of pancreatic duct leak (with video)
    Pancreatic fistula is a challenging yet common adverse event of partial pancreatectomy. Our objective is to determine the feasibility of endoscopic closure of a pancreatic fistula using a combination of a metallic coil and N-butyl-2-cyanoacrylate (NBCA) glue.


    Date de mise en ligne : Mercredi 23 aoűt 2017
    Dan Li, John Woolfrey, Sheng-Fang Jiang, Christopher D. Jensen, Wei K. Zhao, Sanjay Kakar, Monica Santamaria, Greg Rumore, Mary Anne Armstrong, Debbie Postlethwaite, Douglas A. Corley, Theodore R. Levin
    Diagnosis of sessile serrated adenoma after educational training in a large, community-based, integrated healthcare setting
    Sessile serrated adenomas (SSAs) are precursors of 15% to 30% of colorectal cancers but are frequently underdiagnosed. We sought to measure the SSA detection rate (SDR) and predictors of SSA detection after educational training for community gastroenterologists and pathologists.


    Date de mise en ligne : Mercredi 23 aoűt 2017
    Prashant R. Mudireddy, Amrita Sethi, Ali A. Siddiqui, Douglas G. Adler, Jose Nieto, Harshit Khara, Arvind Trindade, Sammy Ho, Petros C. Benias, Peter V. Draganov, Dennis Yang, Shaffer Mok, Bradley Confer, David L. Diehl
    EUS-guided drainage of post-surgical fluid collections using lumen-apposing metal stents: a multicenter study
    Post-surgical fluid collections (PSFCs) are traditionally drained either percutaneously or surgically. Endoscopic drainage offers several advantages compared to either percutaneous or surgical approaches including avoiding repeat surgery, or the need to have a percutaneous drain in place for weeks. There are very little data regarding use of lumen apposing metal stents (LAMSs) in the drainage of PSFCs. We aim to study the technical and clinical success and adverse events of using LAMSs in the drainage of PSFCs.


    Date de mise en ligne : Mardi 22 aoűt 2017
    Maxime Palazzo, Marianna Arvanitakis, Myriam Delhaye, Jacques Devière, Arnaud Lemmers
    Acute suppurative cholangitis due to an impacted pancreatic stone: a rare adverse event in the setting of chronic calcified pancreatitis


    Date de mise en ligne : Mardi 22 aoűt 2017
    Sanjeev S. Solomon, Divyanshoo R. Kohli, George B. Smallfield
    Esophageal Cryoablation Using Retrograde Per-Gastrostomy Ventilation in A Patient with Pharyngoesophageal Stenosis


    Date de mise en ligne : Mardi 22 aoűt 2017
    Chung Yao Yu, Suraj Patel, James Buxbaum
    GIE: At the Focal Point Direct Visualization of IgG4-related Cholangiopathy


    Date de mise en ligne : Mardi 22 aoűt 2017
    Erwin-Jan M van Geenen, Peter P. Siersema
    Stent migration into the abdominal cavity after EUS-guided hepaticogastrostomy


    Date de mise en ligne : Lundi 14 aoűt 2017
    Tonya R. Kaltenbach, Roy M. Soetikno, Rebecca DeVivo, Loren A. Laine, Alan Barkun, Kenneth R. McQuaid, Optimizing Quality of Endoscopy in IBD Group
    Optimizing quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image and video-based teaching
    Varying recommendations regarding the detection and management of dysplasia can lead to uncertainty and may have impeded the uptake of strategies that could improve surveillance in patients with inflammatory bowel disease (IBD). As such, an educational event was held to assist in disseminating the recently published Surveillance for Colorectal Endoscopic Neoplasia Detection and Management in Inflammatory Bowel Disease Patients: International Consensus Recommendations (SCENIC).


    Date de mise en ligne : Vendredi 11 aoűt 2017
    Sébastien Gaujoux, Seray Genc, Sarah Leblanc, Bertrand Dousset, Frédéric Prat
    Insulinoma enucleation after echoendoscopic fiducial placement
    A 72-year-old woman presented with symptoms typical of neuroglucopenia. A fasting test showed organic hypoglycemia. On cross-sectional imaging, including thin-section multidetector CT, magnetic resonance imaging with diffusion weighted imaging,111In-labeled octreotide scanning, and 68Ga-DOTA(0)-Phe(1)-Tyr(3)-Octreotide PET/CT, no lesion was observed. EUS showed a small 8 × 5 mm hypoechogenic lesion in the upper internal part of the head of the pancreas, which was confirmed by EUS-FNA. To facilitate intraoperative localization, a 5-mm EUS-guided gold fiducial marker (Cook Medical, Bloomington, Ind), designed for stereotactic body radiation therapy, was inserted in the lesion (A).


    Date de mise en ligne : Jeudi 10 aoűt 2017
    Nina Gupta, Vani Konda, Uzma Siddiqui
    Gastric cardia lesion with abnormal volumetric laser endomicroscopy imaging


    Date de mise en ligne : Jeudi 10 aoűt 2017
    Michael P. DeMicco, Lucy B. Clayton, Jeff Pilot, Michael S. Epstein, NOCT Study Group
    Novel 1L polyethylene glycol-based bowel preparation NER1006 for overall and right-sided colon cleansing: a randomized controlled phase 3 trial versus trisulfate
    NER1006 is the first 32 fluid ounce (1L) polyethylene glycol-based bowel preparation. This randomized, multicenter, colonoscopist/central reader-blinded Phase 3 non-inferiority trial assessed the efficacy, safety, and tolerability of NER1006 versus trisulfate for bowel cleansing.


    Date de mise en ligne : Jeudi 10 aoűt 2017
    Catherine Hudson, Eric Fontenot, Stephen Landreneau
    Gastric Antral Vascular Ectasia Presents as a Polypoid Mass in a patient with cirrhosis


    Date de mise en ligne : Mercredi 09 aoűt 2017
    Allison R. Schulman, Violeta Popov, Christopher C. Thompson
    Randomized sham-controlled trials in endoscopy: a systematic review and meta-analysis of adverse events
    Sham procedures in endoscopy are used with the intention of controlling for placebo response, potentially allowing more precise evaluation of treatment effect. Nevertheless, this type of study may impose significant risk without potential benefit for those in the sham group. The aim of the current study is to systematically review and analyze the endoscopic literature to assess the safety of sham controls.


    Date de mise en ligne : Lundi 07 aoűt 2017
    Monique T. Barakat, Mohit Girotra, Abhishek Choudhary, Robert J. Huang, Saurabh Sethi, Subhas Banerjee
    A prospective evaluation of radiation-free direct solitary cholangioscopy for the management of choledocholithiasis
    Endoscopy has replaced many radiological studies for the GI tract. However, ERCP remains a hybrid endoscopic-fluoroscopic procedure, which limits its portable delivery, creates delays due to fluoroscopy room unavailability and exposes patients/providers to radiation. We evaluated fluoroscopy/radiation-free management of patients with non-complex choledocholithiasis using direct solitary cholangioscopy (DSC).


    Date de mise en ligne : Jeudi 03 aoűt 2017
    Don C. Codipilly, Hongfei Fang, Jeffrey A. Alexander, David A. Katzka, Karthik Ravi
    Subepithelial esophageal tumors: a single-center review of resected and surveilled lesions
    Subepithelial esophageal tumors (SETs) are frequent incidental findings. Although symptomatic tumors are surgically or endoscopically resected, there is no consensus on the management of asymptomatic esophageal leiomyomas.


    Date de mise en ligne : Vendredi 28 juillet 2017
    Prashanth R. Vennalaganti, Vivek Kaul, Kenneth K. Wang, Gary W. Falk, Nicholas J. Shaheen, Anthony Infantolino, David A. Johnson, Glenn Eisen, Lauren B. Gerson, Michael S. Smith, Prasad G. Iyer, Charles J. Lightdale, Felice Schnoll-Sussman, Neil Gupta, Seth A. Gross, Julian Abrams, Gregory B. Haber, Ram Chuttani, Douglas K. Pleskow, Shivangi Kothari, John R. Goldblum, Yaxia Zhang, Prateek Sharma
    Increased Detection of Barrett’s Esophagus-associated Neoplasia Using Wide-Area Trans-epithelial Sampling: A Multicenter, Prospective, Randomized Trial
    Wide-area transepithelial sampling (WATS) with computer-assisted 3-dimensional analysis is a sampling technique that combines abrasive brushing of the Barrett’s esophagus (BE) mucosa followed by neural network analysis to highlight abnormal-appearing cells.


    Date de mise en ligne : Vendredi 28 juillet 2017
    B.M. Yan, B. Feagan, A. Teriaky, M. Mosli, R. Mohamed, G.S. Williams, E. Yeung, E. Yong, A. Haig, M. Sey, L. Stitt, G.Y. Zou, V. Jairath
    Reliability of EUS indices to detect inflammation in ulcerative colitis
    EUS is a potentially useful modality to assess severity of inflammation in ulcerative colitis (UC). We assessed the reliability of existing EUS indices and correlated them with endoscopic and histologic scores.


    Date de mise en ligne : Vendredi 28 juillet 2017
    Monique T. Barakat, Robert J. Huang, Nirav C. Thosani, Abhishek Choudhary, Mohit Girotra, Subhas Banerjee
    Liver transplant–related anastomotic biliary strictures: a novel, rapid, safe, radiation-sparing, and cost-effective management approach
    Biliary strictures after orthotopic liver transplantation (OLT) are typically managed by sequential ERCP procedures, with incremental dilation of the stricture and stent exchange (IDSE) and placement of new stents. This approach resolves >80% of strictures after 12 months but requires costly, lengthy ERCPs with significant patient radiation exposure. Increasing awareness of the harmful effects of radiation, escalating healthcare costs, and decreasing reimbursement for procedures mandate maximal efficiency in performing ERCP.


    Date de mise en ligne : Mercredi 26 juillet 2017
    Chan Hyuk Park, Jang Han Jung, Eunwoo Nam, Eun Hye Kim, Mi Gang Kim, Jae Hyun Kim, Se Woo Park
    Comparative efficacy of various endoscopic techniques for the treatment of common bile duct stones: A network meta-analysis
    Although various endoscopic techniques have been introduced for successful removal of common bile duct (CBD) stones, the optimal method is not yet clear. We aimed to compare the efficacy of different endoscopic techniques for CBD stone removal.


    Date de mise en ligne : Lundi 24 juillet 2017
    Diane Lorenzo, Théophile Guilbaud, Jean Michel Gonzalez, Alban Benezech, Anne Dutour, Sandrine Boullu, Stéphane Berdah, Thierry Bège, Marc Barthet
    Endoscopic treatment of fistulas after sleeve gastrectomy: a comparison of internal drainage versus closure
    Post-sleeve gastrectomy fistulas (PSGF) are major adverse events of bariatric surgery. The endoscopic management strategy evolved from closure to internal drainage (ID) after 2013. The main objective was to evaluate and compare these different approaches.


    Date de mise en ligne : Lundi 24 juillet 2017
    Yen-I. Chen, Rastislav Kunda, Andrew C. Storm, Hanaa Dakour Aridi, Christopher C. Thompson, Jose Nieto, Ali A. Siddiqui, Theodore James, Shayan Irani, Majidah Bukhari, Olaya Brewer Gutierrez, Amol Agarwal, Lea Fayad, Robert Moran, Nuha Alammar, Omid Sanaei, Marcia I. Canto, Vikesh K. Singh, Todd H. Baron, Mouen A. Khashab
    EUS-guided gastroenterostomy: a multicenter study comparing the direct and balloon-assisted techniques
    Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is a developing modality in the management of gastric outlet obstruction (GOO) with several technical approaches including the direct and balloon-assisted techniques. The aim of this study is to compare the direct with the balloon-assisted modality while further defining the role of EUS-GE in GOO.


    Date de mise en ligne : Lundi 24 juillet 2017
    Anthony Yuen Bun Teoh, Charing Ching Ning Chong, Wing Wa Leung, Simon Kin Cheong Chan, Yee Kit Tse, Enders Kwok Wai Ng, Paul Bo San Lai, Justin Che Yuen Wu, James Yun Wong Lau
    Electroacupuncture-reduced sedative and analgesic requirements for diagnostic EUS: a prospective, randomized, double-blinded, sham-controlled study
    The role of electroacupuncture (EA) in reducing sedative and analgesic requirements during EUS is uncertain. The aim of the current study is to investigate the efficacy of EA in reducing procedure-related pain and discomfort during EUS.


    Date de mise en ligne : Lundi 24 juillet 2017
    Brisas M. Flores, Anthony OĘĽConnor, Alan C. Moss
    Impact of Mucosal Inflammation on Risk of Colorectal Neoplasia in Patients with Ulcerative Colitis: A Systematic Review and Meta-Analysis
    Long-standing ulcerative colitis is an established risk factor for colorectal neoplasia. A number of observational studies have suggested that evidence of mucosal inflammation (endoscopic or histologic) is associated with a greater risk for colorectal neoplasia than is mucosal healing. Our goal was to systematically analyze the risk of colorectal neoplasia in ulcerative colitis patients with ongoing mucosal inflammation to better inform surveillance strategies.


    Date de mise en ligne : Vendredi 21 juillet 2017
    John C. Fang, Gary Faerber, Jewel Samadder
    Digital rectal examination for prostate cancer screening performed with colonoscopy for colon cancer screening: Two for the price of one


    Date de mise en ligne : Jeudi 20 juillet 2017
    Soo Jung Park, Hyojin Park, Yong Chan Lee, Chang Hwan Choi, Tae Joo Jeon, Jun Chul Park, Jie-Hyun Kim, Young Hoon Youn, Yu Jin Kim, Jae Hak Kim, Kwang Jae Lee, Sun Gyo Lim, Hyungkil Kim, Byoung Wook Bang
    Effect of scheduled second-look endoscopy on peptic ulcer bleeding: a prospective randomized multicenter trial
    This study aimed to investigate the effectiveness of scheduled second-look endoscopy (EGD) with endoscopic hemostasis on peptic ulcer rebleeding and to identify the risk factors related to the need for second-look EGD.


    Date de mise en ligne : Mercredi 19 juillet 2017
    Elizabeth Rajan, Badr Al-Bawardy, Christopher J. Gostout, Louis Michele Wong Kee Song, Jodie L. Deters, Mary A. Knipschield, Cheryl E. Bernard, Gianrico Farrugia
    Endoscopic muscle biopsy sampling of the duodenum and rectum: a pilot survival study in a porcine model to detect myenteric neurons
    Small bowel and colorectal muscle biopsy sampling requires a surgical approach. Advancing our understanding of the pathophysiology of motility disorders, such as functional bowel disorders, intestinal pseudo-obstruction, and slow-transit constipation, is hindered by our inability to noninvasively obtain muscularis propria (MP) for evaluation of multiple cell types, including myenteric neurons. The aims of this study were to determine (1) technical feasibility, reproducibility, and safety of performing duodenal endoscopic muscle biopsy sampling (dEMB) and rectal endoscopic muscle biopsy sampling (rEMB) using a clip-assist technique and (2) the presence of myenteric neurons in tissue samples.


    Date de mise en ligne : Mercredi 19 juillet 2017
    Akira Dobashi, Elizabeth Rajan, Mary A. Knipschield, Christopher J. Gostout
    Endoscopic full-thickness resection using suture loop needle T-tag tissue anchors in the porcine stomach (with video)
    Endoscopic full-thickness resection (EFTR) is still challenging, and a reliable technique is desirable. The aim of this study was to evaluate the feasibility of controlled EFTR using a pseudopolyp made from suture loop needle T-tag (SLNT) tissue anchors in ex vivo porcine stomachs.


    Date de mise en ligne : Mercredi 19 juillet 2017
    Shivkumar Budihal, Krish Ragunath
    Cardiac ischemia after epinephrine injection during EMR for a large rectal polyp


    Date de mise en ligne : Mardi 18 juillet 2017
    Jiaqi Dong, Kunyan Wei, Jiaqi Deng, Xi Zhou, Xiaomei Huang, MingMing Deng, Muhan LĂĽ
    Effects of antithrombotic therapy on bleeding after endoscopic submucosal dissection
    Bleeding is the most common adverse event after endoscopic submucosal dissection (ESD). Although several studies have reported on the use of antithrombotic agents and post-ESD bleeding, many issues remain controversial. We conducted a meta-analysis and systematic review to evaluate the effects of antithrombotic therapy on post-ESD bleeding.


    Date de mise en ligne : Samedi 15 juillet 2017
    Haruka Toyonaga, Masashi Fukushima, Tetsuro Inokuma, Yukihiro Imai
    Mantle cell lymphoma involving the esophagus evaluated by magnifying endoscopy with narrow-band imaging
    A 62-year-old man was referred because of intestinal polyposis. Physical examination revealed diffuse lymphadenopathy and splenomegaly. Laboratory tests showed lactate dehydrogenase of 173 U/L (reference range [RR] 120-250 U/L) and soluble interleukin-2 receptor of 3264 U/mL (RR 220-530 U/mL). Colonoscopy revealed multiple smooth polyps (<10 mm) in the terminal ileum and colon. EGD to determine the extent of the disease revealed multiple whitish flat nodules (<5 mm) in the pharynx and esophagus by white light (A) and narrow-band imaging (B).


    Date de mise en ligne : Samedi 15 juillet 2017
    Bing-Rong Liu, Ji-Tao Song, Zhong-Hong Liu, Ge Lou, Ling-Jian Kong
    Endoscopic transcecal appendectomy: the first human case report
    A 53-year-old man was transferred to our hospital for the management of a cecal polyp near the appendiceal orifice. At colonoscopy, no appendiceal orifice was seen; instead, a mucosal bulge was seen (A). An appendiceal cyst was considered. Because the appendiceal lumen directly connects to the cecum, colonoscopic appendectomy was considered. After informed consent was obtained from the patient, an endoscopic full-thickness incision was made around the appendiceal orifice with a Hook (Olympus, Tokyo, Japan) and IT2 knife (Olympus, Tokyo, Japan).


    Date de mise en ligne : Samedi 15 juillet 2017
    Tatsuya Koshitani, Shuji Nakagawa, Yoshito Itoh
    EUS-guided antegrade stent placement for unresectable malignant hilar biliary strictures by use of a stent-in-stent method
    EUS-guided biliary drainage (EUS-BD) used for treating unresectable malignant hilar biliary strictures (UMHBS) is still challenging; however, a bilateral self-expandable metal stent (SEMS) can be deployed by a stent-in-stent method under EUS guidance. A 65-year-old woman had UMHBS caused by hilar lymph node metastasis originating from ovarian cancer (A). EUS-guided antegrade stent placement was selected for obstructive jaundice because she had a duodenal stenosis and massive ascites. The intrahepatic bile duct (B3) was punctured by a 19-gauge needle from the upper body of the stomach under EUS guidance (B), and a 0.025-inch guidewire with an angled tip was introduced to the right anterior sectoral duct, followed by the deployment of a SEMS (Zilver 635 biliary self-expanding metal stent; Cook Medical, Tokyo, Japan) bridging between the right and left hepatic ducts (C).


    Date de mise en ligne : Samedi 15 juillet 2017
    Marcia Irene Canto, Julian A. Abrams, Hannah T. KĂĽnzli, Bas Weusten, Yoshihiro Komatsu, Blair A. Jobe, Charles J. Lightdale
    Nitrous oxide cryotherapy for treatment of esophageal squamous cell neoplasia: initial multicenter international experience with a novel portable cryoballoon ablation system (with video)
    Early esophageal squamous cell neoplasia (ESCN) can be successfully treated by EMR, endoscopic submucosal dissection (ESD), or radiofrequency ablation. A new portable, battery-powered cryotherapy system using nitrous oxide (cryoballoon focal ablation system [CbFAS]) has been used for Barrett’s esophagus. It consists of a small hand-held device containing liquid nitrous oxide, which converts to gas within a low-pressure–compliant through-the-scope balloon and freezes targeted mucosa in contact with the balloon.


    Date de mise en ligne : Samedi 15 juillet 2017
    Mohammad Esmadi, Dina Ahmad, Kurt Fisher, Alexander Hewlett
    Atypical appearance of a rectal Dieulafoy lesion
    A 22-year-old previously healthy Asian woman presented because of multiple episodes of profuse bright red blood from her rectum for 1 day. Colonoscopy revealed a 5-mm pedunculated “polyp” with superficial erosion in the rectum (A). Because of the atypical appearance and a fear about the underlying vascular structure, the polyp was lifted with normal saline solution and epinephrine (B) and then removed with a hot snare (C). The defect was closed with a clip. There was no bleeding after polypectomy.


    Date de mise en ligne : Samedi 15 juillet 2017
    Shoichiro Mine, Eisuke Ozawa, Ken Ohnita, Kuniko Abe, Kazuhiko Nakao
    A case of IgG4-related disease presenting with multiple gastric submucosal tumors
    A 64-year-old man with swelling of the bilateral submandibular salivary glands was referred to our hospital in July 2016. EGD revealed numerous small submucosal nodules ranging from 3 to 10 mm in size, mainly distributed in the gastric fundus and body (A). The papilla of Vater was also swollen (B). Histopathologic examination of biopsy specimens taken from these submucosal nodules gave inconclusive results. Laboratory data showed high serum levels of total immunoglobulin G (IgG) (2817 mg/dL) and IgG4 (1210 mg/dL).


    Date de mise en ligne : Vendredi 14 juillet 2017
    EvĹľen Machytka, Marek BuĹľga, Pavel Zonca, David B. Lautz, Marvin Ryou, Donald C. Simonson, Christopher C. Thompson
    Partial jejunal diversion using an incisionless magnetic anastomosis system: 1-year interim results in patients with obesity and diabetes
    Most patients with type 2 diabetes mellitus have obesity. Studies show that bariatric surgery is superior to medical treatment for remission of type 2 diabetes mellitus. Nevertheless, very few patients undergo surgery, and a less-invasive endoscopic alternative is desirable.


    Date de mise en ligne : Vendredi 14 juillet 2017
    Seiichiro Abe, Prasad G. Iyer, Ichiro Oda, Nobuo Kanai, Yutaka Saito
    Approaches for stricture prevention after esophageal endoscopic resection
    Endoscopic resection of extensive esophageal lesions has become more common as endoscopic resection techniques and equipment have developed. However, extensive esophageal endoscopic resections can cause postoperative esophageal strictures, which have a negative impact on the quality of life of patients. We aimed to review current treatments and innovative approaches to prevent esophageal strictures after widespread endoscopic resection of esophageal lesions.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Hai Yun Shi, Francis K.L. Chan, Akira Higashimori, Moe Kyaw, Jessica Y.L. Ching, Heyson C.H. Chan, Joey C.H. Chan, Anthony W.H. Chan, Kelvin L.Y. Lam, Raymond S.Y. Tang, Justin C.Y. Wu, Joseph J.Y. Sung, Siew C. Ng
    A prospective study on second-generation colon capsule endoscopy to detect mucosal lesions and disease activity in ulcerative colitis (with video)
    Mucosal healing is the goal for ulcerative colitis (UC) therapy, but it needs to be confirmed via colonoscopy. Colon capsule endoscopy (CCE) is a noninvasive technique for colon investigation. Our study investigated the accuracy of second-generation CCE (CCE-2) in assessing mucosal lesions and disease activity in UC.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Hyo-Joon Yang, Sang Gyun Kim, Joo Hyun Lim, Ji Min Choi, Sooyeon Oh, Jae Yong Park, Seung Jun Han, Jung Kim, Hyunsoo Chung, Hyun Chae Jung
    Novel risk stratification for metachronous recurrence after curative endoscopic submucosal dissection for early gastric cancer
    This study stratified the risk of developing metachronous gastric cancer (MGC) after curative endoscopic submucosal dissection (ESD) of early gastric cancer (EGC) to enable customization of endoscopic surveillance for MGC.


    Date de mise en ligne : Jeudi 13 juillet 2017
    David J. Tate, Mahesh Jayanna, Halim Awadie, Lobke Desomer, Ralph Lee, Steven J. Heitman, Mayenaaz Sidhu, Kathleen Goodrick, Nicholas G. Burgess, Hema Mahajan, Duncan McLeod, Michael J. Bourke
    A standardized imaging protocol for the endoscopic prediction of dysplasia within sessile serrated polyps (with video)
    Dysplasia within sessile serrated polyps (SSPs) is difficult to detect and may be mistaken for an adenoma, risking incomplete resection of the background serrated tissue, and is strongly implicated in interval cancer after colonoscopy. The use of endoscopic imaging to detect dysplasia within SSPs has not been systematically studied.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Julian A. Abrams, Sri Komanduri, Nicholas J. Shaheen, Zengri Wang, Richard I. Rothstein
    Radiofrequency ablation for the treatment of weight regain after Roux-en-Y gastric bypass surgery
    Roux-en-Y gastric bypass (RYGB) surgery is an established modality for the treatment of morbid obesity. However, approximately one-quarter of patients experience weight regain after initially successful weight loss. Endoscopic therapy targeting the gastric remnant pouch represents a novel potential strategy to re-induce weight loss in this population. We performed a pilot trial of radiofrequency ablation (RFA) of the gastric remnant pouch after RYGB to determine feasibility, safety, and efficacy for weight loss.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Gabriel D. Lang, Cassandra Fritz, Trisha Bhat, Koushik K. Das, Faris M. Murad, Dayna S. Early, Steven A. Edmundowicz, Vladimir M. Kushnir, Daniel K. Mullady
    EUS-guided drainage of peripancreatic fluid collections with lumen-apposing metal stents and plastic double-pigtail stents: comparison of efficacy and adverse event rates
    Transmural drainage with double-pigtail plastic stents (DPPSs) was the mainstay of endoscopic therapy for symptomatic peripancreatic fluid collections (PPFCs) until the introduction of lumen-apposing covered self-expanding metal stents (LAMSs). Currently, there are limited data regarding the efficacy and adverse event rate of LAMSs compared with DPPSs.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Laurien J. van Nimwegen, Leon M.G. Moons, Joost M.J. Geesing, L. René Arensman, Miangela Laclé, Ivo A.M.J. Broeders, Peter P. Viergever, John N. Groen, Koen Kessels, Matthijs P. Schwartz
    Extent of unnecessary surgery for benign rectal polyps in the Netherlands
    Minimally invasive techniques are available to safely and efficaciously remove even the largest rectal polyps. This study aimed to investigate the magnitude of cases still referred for radical rectal surgery and the reasons for these referrals and to perform a re-evaluation of cases potentially suitable for endoscopic therapy.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Rajat Garg, Heidi D. Lehrke, Barham K. AbuDayyeh, Tarun Rustagi
    Incidental giardiasis diagnosed during transduodenal EUS-FNA
    A 64-year-old man underwent staging EUS for evaluation of cholangiocarcinoma before liver transplantation. EUS showed a hilar mass consistent with cholangiocarcinoma along with 2 small lymph nodes in the aortocaval space. EUS-guided transduodenal FNA of the larger lymph node was performed. Rapid on-site cytologic examination showed an adequate specimen with no evidence of malignancy; however, numerous pear-shaped, binucleated, flagellated organisms consistent with trophozoites of Giardia lamblia were identified (A and B, May-Grunwald-Giemsa, orig.


    Date de mise en ligne : Vendredi 07 juillet 2017
    Yoshihiro Furuichi, Takuji Gotoda, Yoshitaka Kasai, Hirohito Takeuchi, Yuu Yoshimasu, Takashi Kawai, Takao Itoi
    Role of dual red imaging to guide intravariceal sclerotherapy injection of esophageal varices (with videos)
    Dual red imaging (DRI) is a novel image-enhanced endoscopy technique that can increase the visibility and predict the depth of esophageal varices (EVs). The recurrence rate of EVs after endoscopic injection sclerotherapy (EIS) reportedly decreases by intravariceal injection of a sclerosant. We evaluated prospectively whether the EIS success rate was increased by DRI compared with the white-light imaging (WLI) mode.


    Date de mise en ligne : Mercredi 05 juillet 2017
    Emma Z. Mi, Ella Z. Mi, Massimiliano di Pietro, Maria O’Donovan, Richard H. Hardwick, Susan Richardson, Hisham Ziauddeen, Paul C. Fletcher, Carlos Caldas, Marc Tischkowitz, Krish Ragunath, Rebecca C. Fitzgerald
    Comparative study of endoscopic surveillance in hereditary diffuse gastric cancer according to CDH1 mutation status
    Hereditary diffuse gastric cancer (HDGC) accounts for 1% of gastric cancer cases. For patients with a germline CDH1 mutation, risk-reducing gastrectomy is recommended. However, for those delaying surgery or for families with no causative mutation identified, regular endoscopy is advised. This study aimed to determine the yield of signet ring cell carcinoma (SRCC) foci in individuals with a CDH1 pathogenic variant compared with those without and how this varies with successive endoscopies.


    Date de mise en ligne : Mardi 04 juillet 2017
    Roberto Di Mitri, Filippo Mocciaro, Maurizio Lipani
    One-session “2-step” technique for endoscopic full-thickness resection of a large rectal adenocarcinoma: when it is possible, overcome the lesion’s size
    A 73-year-old man with a history of serious comorbidities underwent screening colonoscopy with evidence of a large rectal polypoid lesion (30 mm in diameter) 4 cm from the anal verge (A). Examination of biopsy specimens showed a well-differentiated adenocarcinoma (AC), and at EUS the tumor did not cross the muscularis propria (MP); invasion of the perirectal lymph nodes was also excluded (B). CT scans of the chest and abdomen were negative for metastasis. Because of the patient’s high anesthesiologic and surgical risk, after obtaining informed consent, we decided to perform a “2-step” endoscopic full-thickness resection (EFTR).


    Date de mise en ligne : Mardi 04 juillet 2017
    Michael J. Bartel, Amitabh Srivastava, Stuart Gordon, Richard I. Rothstein, Heiko Pohl
    Subsquamous intestinal metaplasia is common in treatment-naïve Barrett’s esophagus
    Barrett’s intestinal metaplasia may extend beneath normal squamous epithelium at the squamocolumnar junction (SCJ) and therefore escape surveillance biopsy sampling. The prevalence of subsquamous intestinal metaplasia (SSIM) in patients undergoing Barrett's esophagus (BE) surveillance is unknown. Our aim was to examine the prevalence and distribution of SSIM proximal to the SCJ in patients undergoing BE surveillance.


    Date de mise en ligne : Vendredi 30 juin 2017
    Silvia Carrara, Milena Di Leo, Paola Spaggiari, Pietro Francesco Bagnoli, Alessandro Repici
    Rectal metastases from malignant mucinous cystic neoplasm of the pancreas mimicking a rectal carcinoma
    A 38-year-old woman was admitted with abdominal pain. She underwent colonoscopy and CT scan, which revealed a rectal adenocarcinoma and a pancreatic tail tumor. Pancreatic EUS and EUS-FNA showed a malignant mucinous cystic neoplasm of the pancreas with infiltration of the surrounding parenchyma. Rectal EUS showed a 20-mm ulcerative depressed lesion (A), with convergence of mucosal folds. The lesion corresponded to a thickened rectal wall with loss of layer structure, strictly adherent to a hypoechoic, hypovascularized hard nodule with irregular margins in the mesorectum (B).


    Date de mise en ligne : Vendredi 30 juin 2017
    Sabrina Sy, Hassan Siddiki, Jennifer Horsley-Silva, Thomas Byrne, Dora Lam-Himlin
    Sevelamer resin bezoar presenting as a cecal mass
    A 69-year-old man with a history of type 2 diabetes, hypertension, diabetic nephropathy, chronic kidney disease, and gastroesophageal reflux disease presented to the emergency department with abdominal pain described as 9 out of 10 with band-like wrapping around his back. A physical examination revealed a soft nondistended abdomen, and after an unremarkable abdominal CT scan, the patient was discharged. Outpatient follow-up consisted of colonoscopy, which revealed a 35-mm mass lesion in the cecum occupying 40% of the lumen (A).


    Date de mise en ligne : Vendredi 30 juin 2017
    Ken Kamata, Mamoru Takenaka, Kosuke Minaga, Masatoshi Kudo
    Utility of contrast-enhanced harmonic EUS for evaluating the effects of steroid therapy in a case of immunoglobulin G4–negative focal autoimmune pancreatitis
    A 75-year-old woman was asymptomatic, but contrast-enhanced abdominal CT for hyperamylasemia (1302 U/L) revealed a hypovascular lesion in the pancreatic body and a slightly dilatated pancreatic duct on the tail side of the lesion. Her serum immunoglobulin G4 level was 62.9 mg/dL. On positron emission tomography (PET)-CT, the maximum standardized uptake value at the mass lesion was 3.22. Conventional EUS revealed a 25-mm hypoechoic lesion in the pancreatic body. Contrast-enhanced harmonic EUS was then performed with contrast agent (0.015 mL/kg; Sonazoid; Daiichi-Sankyo, Tokyo, Japan).


    Date de mise en ligne : Samedi 24 juin 2017
    Ramkaji Baniya, Sunil Upadhaya, Subash Chandra Subedi, Jahangir Khan, Prabin Sharma, Tabrez Shaik Mohammed, Ghassan Bachuwa, Laith H. Jamil
    Balloon enteroscopy versus spiral enteroscopy for small-bowel disorders: a systematic review and meta-analysis
    Two novel enteroscopic procedures, balloon enteroscopy and spiral enteroscopy, have revolutionized the diagnostic and therapeutic approach to small-bowel disorders. These disorders that historically required surgical interventions are now investigated and managed nonsurgically. Only a few weakly powered studies have compared the outcomes of spiral enteroscopy and balloon enteroscopy. We conducted a systematic review and meta-analysis to compare the efficacy and safety of these 2 procedures.


    Date de mise en ligne : Jeudi 22 juin 2017
    Wai K. Leung, Hsiu J. Ho, Jaw-Town Lin, Ming-Shiang Wu, Chun-Ying Wu
    Prior gastroscopy and mortality in patients with gastric cancer: a matched retrospective cohort study
    The role of prior gastroscopy on the outcome of patients with gastric cancer remains unknown. This study determines the association between intervals of prior gastroscopy and mortality in patients with gastric cancer.


    Date de mise en ligne : Jeudi 22 juin 2017
    Matthew A. Kluge, J. Lucas Williams, Connie K. Wu, Brian C. Jacobson, Paul C. Schroy, David A. Lieberman, Audrey H. Calderwood
    Inadequate Boston Bowel Preparation Scale scores predict the risk of missed neoplasia on the next colonoscopy
    The risks of missed findings after inadequate bowel preparation are not fully characterized in a diverse cohort. We aimed to evaluate the likelihood of missed polyps after an inadequate preparation as assessed by using the Boston Bowel Preparation Scale (BBPS).


    Date de mise en ligne : Jeudi 22 juin 2017
    Zhouwen Tang, Daniel S. Zhang, Aaron P. Thrift, Kalpesh K. Patel
    Impact of cap-assisted colonoscopy on the learning curve and quality in colonoscopy: a randomized controlled trial
    Colonoscopy competency assessment in trainees traditionally has been informal. Comprehensive metrics such as the Assessment of Competency in Endoscopy (ACE) tool suggest that competency thresholds are higher than assumed. Cap-assisted colonoscopy (CAC) may improve competency, but data regarding novice trainees are lacking. We compared CAC versus standard colonoscopy (SC) performed by novice trainees in a randomized controlled trial.


    Date de mise en ligne : Mercredi 21 juin 2017
    Qisheng Zhang, Peng Gao, Bin Han, Jianhua Xu, Yucui Shen
    Polypectomy for complete endoscopic resection of small colorectal polyps
    Small colorectal polyps are encountered frequently and may be incompletely removed during colonoscopy. The optimal technique for removal of small colorectal polyps is uncertain. The aim of this study was to compare the incomplete resection rate (IRR) by using EMR or cold snare polypectomy (CSP) for the removal of small adenomatous polyps.


    Date de mise en ligne : Mardi 20 juin 2017
    Yaser Meeralam, Khalil Al-Shammari, Mohammad Yaghoobi
    Diagnostic accuracy of EUS compared with MRCP in detecting choledocholithiasis: a meta-analysis of diagnostic test accuracy in head-to-head studies
    There is a wide range of reported sensitivity and specificity for EUS and MRCP in the diagnosis of choledocholithiasis, with lack of a proper meta-analysis of diagnostic test accuracy by using head-to-head comparison. Here, we aimed to compare the diagnostic accuracy of EUS and MRCP in detecting choledocholithiasis by using appropriate methodology recommended by the Cochrane Collaboration.


    Date de mise en ligne : Mercredi 14 juin 2017
    Hyun Gun Kim, Young-Seok Cho, Jae Myung Cha, Jeong Eun Shin, Kyeong Ok Kim, Hyo-Joon Yang, Hoon Sup Koo, Young-Eun Joo, Sun-Jin Boo
    Risk of metachronous neoplasia on surveillance colonoscopy in young patients with colorectal neoplasia
    Few prior reports exist that address the appropriate colonoscopy surveillance interval for individuals <50 years old. We compared the risk of metachronous neoplasia between younger (20-49 years) and older (50-54 years) cohorts.


    Date de mise en ligne : Mercredi 14 juin 2017
    Ken Kamata, Mamoru Takenaka, Shunsuke Omoto, Takeshi Miyata, Kosuke Minaga, Kentaro Yamao, Hajime Imai, Toshiharu Sakurai, Naoshi Nishida, Takaaki Chikugo, Yasutaka Chiba, Ippei Matsumoto, Yoshifumi Takeyama, Masatoshi Kudo
    Impact of avascular areas, as measured by contrast-enhanced harmonic EUS, on the accuracy of fine-needle aspiration for pancreatic adenocarcinoma
    Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is used for the diagnosis of pancreatic adenocarcinoma, but sometimes the method results in a false negative. Occasionally, an avascular area may be observed within the pancreatic adenocarcinoma tumor during contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS). The aim of this study was to evaluate whether the diagnostic sensitivity of EUS-FNA for pancreatic adenocarcinoma was affected by the presence of avascularity on CH-EUS.


    Date de mise en ligne : Mardi 13 juin 2017
    Kazuki Boda, Shiro Oka, Shinji Tanaka, Shinji Nagata, Masaki Kunihiro, Toshio Kuwai, Yuko Hiraga, Akira Furudoi, Motomi Terasaki, Koichi Nakadoi, Makoto Higashiyama, Hideharu Okanobu, Morihisa Akagi, Kazuaki Chayama
    Clinical outcomes of endoscopic submucosal dissection for colorectal tumors: a large multicenter retrospective study from the Hiroshima GI Endoscopy Research Group
    Although advanced high-volume centers have reported good outcomes of colorectal endoscopic submucosal dissection (ESD), a limited number of highly skilled experts in specialized institutions performed these procedures. We undertook a retrospective multicenter survey, which included nonspecialized hospitals, to investigate the clinical outcomes of colorectal ESD.


    Date de mise en ligne : Samedi 10 juin 2017
    Chan Hyuk Park, Se Woo Park, Bomi Hyun, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi
    Efficacy and safety of etomidate-based sedation compared with propofol-based sedation during ERCP in low-risk patients: a double-blind, randomized, noninferiority trial
    Etomidate is a short-acting intravenous hypnotic with a safety profile that is superior to alternative drugs such as propofol. However, there is a lack of evidence on the safety of etomidate in ERCP. The objective of this study was to compare efficacy and safety profiles of etomidate and propofol for endoscopic sedation.


    Date de mise en ligne : Jeudi 08 juin 2017
    Stephen M. Vindigni, Hejin Hahn, Qing Zhang
    Intermittent obstructive symptoms in a patient with diphyllobothriasis
    A 68-year-old man with hypertension, sleep apnea, and GERD presented to an outpatient gastroenterology clinic with worsening constipation, bloating, mild diffuse abdominal pain, and nausea. He described passing formed, nonbloody stools with mucus, for which he had been using saline solution enemas, with minimal relief. He described a feeling of incomplete evacuation with associated abdominal pressure and had modified his diet to mostly liquids, with an improvement in symptoms. The results of his examination were normal overall, with bowel sounds present and a nontender abdomen.


    Date de mise en ligne : Mardi 06 juin 2017
    Iyad Khamaysi, Alain Suissa
    Hemobilia
    A 69-year-old woman was admitted with right upper quadrant abdominal pain, melena, and jaundice (Quincke's triad). Her medical history was remarkable for hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease), with multiple prior episodes of epistaxis and the need for packed red blood cell transfusions. On physical examination, she appeared to be jaundiced and had right upper quadrant tenderness to palpation. Laboratory tests revealed elevated liver transaminases and direct hyperbilirubinemia.


    Date de mise en ligne : Mardi 06 juin 2017
    Eric M. Nelsen, Daniel E. Abbott, Patrick R. Pfau, Mark E. Benson
    EUS core biopsy leading to duodenal brunneroma diagnosis
    A 56-year-old man presented with vague symptoms of fullness and early satiety. Ultimately, upper endoscopy revealed a large duodenal polyp at least 4 cm long with occasional retrograde protrusion through the pylorus into the stomach (A). Biopsy specimens from upper endoscopy demonstrated duodenal mucosa with gastric foveolar metaplasia. The patient underwent EUS to better characterize the lesion, which confirmed a 3.9-cm lesion that appeared to originate from within the deep mucosa, with no involvement of the muscularis propria (B).


    Date de mise en ligne : Lundi 05 juin 2017
    Roberto Di Mitri, Filippo Mocciaro, Antonio Maiorana, Walter Alio, Ambrogio Orlando
    Endoscopic rescue treatment in a pregnant ulcerative colitis patient with a severe colonic stricture: a conservative approach to bring the pregnancy to term
    A 28-year-old woman with ulcerative colitis, 29 weeks into her first pregnancy, was admitted because of constipation, vomiting, and severe bloating. An abdominal radiograph and MRI revealed a transverse colon of 12.8 cm (A) secondary to a sigmoid stricture (B). The abdominal radiograph (A, left) and MRI (A, right) showed the dilated colon (yellow arrow) resulting from colonic stricture (red arrow) and the fetus (green arrow).


    Date de mise en ligne : Samedi 03 juin 2017
    Noelia Alcaide, Sara Lorenzo Pelayo, Carmen Alonso Martin, Ana Macho Conesa, Francisco Blanco-Antona
    Colovesical fistula: visualization of the bladder during colonoscopy
    An 82-year-old man with hypogastric pain, fecaluria, and pneumaturia was admitted to the hospital. The patient had undergone surgery for rectal carcinoma with adjuvant radiotherapy 15 years earlier and 2 transurethral resections for bladder carcinoma 7 years earlier. Subsequently, the patient experienced several adverse events, including intestinal obstruction that required surgery, anastomotic stenosis treated with endoscopic dilations, radiation colitis, intravesical lithiasis, and ureteral stenosis managed with percutaneous nephrostomy.


    Date de mise en ligne : Samedi 03 juin 2017
    Xiaoyan Ning, Biao Liang, Qinyi Liu, Xiaowu Chen, Ming Xu
    Gastric inflammatory myofibroblastic tumor identified as ectopic pancreas and treated by endoscopic submucosal dissection


    Date de mise en ligne : Vendredi 02 juin 2017
    Jessica R. Allegretti, Zain Kassam, Majdi Osman, Shrish Budree, Monika Fischer, Colleen R. Kelly
    The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection
    Clostridium difficile infection is the most common health care–associated infection in the United States. Recently, fecal microbiota transplantation (FMT) has emerged as an effective and safe therapy for recurrent C difficile infection; however, despite rapid adoption there is no standardized clinical approach. Given the rapid adoption of FMT, in part because of stool banks, there is a need for a practical primer for clinicians to safely perform FMT. Accordingly, we aim to provide a simple approach entitled the 5D FMT framework to guide physicians.


    Date de mise en ligne : Vendredi 02 juin 2017
    Hiroyuki Hatamori, Masaya Wada, Youhei Taniguchi, Tetsuro Inokuma
    Pancreatic pseudocyst localized in the gastric wall after EUS-guided FNA of type 1 autoimmune pancreatitis
    A 67-year-old man with diffuse enlargement of the pancreas suspected to have type 1 autoimmune pancreatitis (AIP) underwent EUS-guided FNA to confirm the pathologic diagnosis (A). FNA was performed through a transgastric approach, and 5 passes were made with a 21G needle with attention to avoid puncture of the main pancreatic duct. The pathologic result was consistent with AIP. Five days later, the patient was admitted to our hospital with abdominal pain and vomiting. A CT scan showed a newly developed 7 × 6 cm cystic mass in the gastric wall with no fluid collection in the retroperitoneal space (B, C).


    Date de mise en ligne : Jeudi 01 juin 2017
    Wouter F.W. Kappelle, Daisy Walter, Paul H. Stadhouders, Hendrik J.A. Jebbink, Frank P. Vleggaar, Peter J. van der Schaar, Jan Willem Kappelle, Ingeborg van der Tweel, Medard F.M. Van den Broek, Frank J. Wessels, Peter D. Siersema, Jan F. Monkelbaan
    Electromagnetic-guided placement of nasoduodenal feeding tubes versus endoscopic placement: a randomized, multicenter trial
    Electromagnetic-guided placement (EMP) of a nasoduodenal feeding tube by trained nurses is an attractive alternative to EGD-guided placement (EGDP). We aimed to compare EMP and EGDP in outpatients, ward patients, and critically ill patients with normal upper GI anatomy.


    Date de mise en ligne : Jeudi 01 juin 2017
    Bram Verstockt, Annelien Van Driessche, Marc De Man, Pieter van der Spek, Koen Hendrickx, Veerle Casneuf, Pieter Dobbels, Yves Van Molhem, Jo Vandervoort
    Ten-year survival after endoscopic stent placement as a bridge to surgery in obstructing colon cancer
    Self-expandable metal stents are used increasingly in the treatment of obstructing colorectal cancer (CRC). Although endoscopic colon stenting is widely accepted in palliation, disagreement exists about its role in a curative setting. This study aims to describe long-term survival data in a large patient group treated with colon stenting as a bridge to surgery for CRC.


    Date de mise en ligne : Mardi 30 mai 2017
    Yutaka Mitsunaga, Toshihiro Nishizawa, Ai Fujimoto, Aya Sasaki, Naohisa Yahagi
    Successful endoscopic submucosal dissection for superficial esophageal cancer on solitary esophageal varix
    Solitary esophageal varix is found in approximately 1% of all patients undergoing upper digestive endoscopy. Here we report a unique case of superficial esophageal cancer on a solitary esophageal varix successfully resected by endoscopic submucosal dissection (ESD). An 80-year-old man underwent upper GI endoscopy at his annual checkup. A slight reddish area was found on an esophageal solitary varix (A), and it was diagnosed as esophageal cancer by narrow-band imaging (NBI) magnification, which showed a brownish area (B) and a dilated irregular intrapapillary capillary loop (C).


    Date de mise en ligne : Mardi 30 mai 2017
    Kyosuke Tanaka, Yasuhiko Hamada, Misaki Nakamura, Reiko Yamada, Yoshiyuki Takei
    Hymenolepis nana infection detected by magnifying colonoscopy with narrow-band imaging (with video)
    A 29-year-old man with Crohn’s disease underwent colonoscopy because of postprandial abdominal pain without diarrhea. Remission of Crohn’s ileocolitis had been achieved by the administration of infliximab every 8 weeks. Colonoscopy revealed a thin white object (A), which looked like a small strand of white mucus. Magnifying endoscopy revealed slow movement (B), and narrow-band imaging (NBI) produced a clearer image (C; Video 1, available online at www.giejournal.org). Endoscopic removal of the tapeworm by biopsy forceps was performed.


    Date de mise en ligne : Mardi 30 mai 2017
    Nitin Vashistha, Suneel Chakravarty, Dinesh Singhal
    Cronkhite-Canada syndrome
    A 36-year-old man was seen with generalized weakness, watery diarrhea, and loss of weight (>15 kg) for 4 months. On examination he had a thin build and his vital signs were stable. He had a dry, swollen tongue with loss of papillae (A). His nail beds were soft and spongy, and the distal parts were discolored. Furthermore, there were hyperpigmented patches over his palms (B). EGD revealed a normal esophagus with marked hypertrophy of the gastric folds (C). A colonoscopy showed multiple sessile polyps throughout the colon and rectum (D).


    Date de mise en ligne : Mardi 30 mai 2017
    Yuji Maehata, Yoshifumi Hori, Minako Hirahashi, Hidetaka Yamamoto, Motohiro Esaki
    Diffuse gastric metastases from salivary duct carcinoma
    A 64-year-old man underwent a right parotidectomy for a parotid gland tumor. Histologic examination revealed poorly differentiated adenocarcinoma with lymph node metastases, and the tumor was diagnosed as salivary duct carcinoma (SDC). Adjuvant chemotherapy was performed for 8 months until CT revealed no residual lesions of SDC. Thirteen months after the surgery, he underwent surveillance EGD and was referred to our hospital for scrutiny of the gastric lesions. Under EGD, thickened gastric folds in the greater curvature of the gastric corpus were discontinuously and ambiguously identified (A), and the surface of these lesions was reddish and coarse (B).


    Date de mise en ligne : Samedi 27 mai 2017
    Yoshinobu Okabe, Tomoyuki Ushijima, Masafumi Yasunaga, Yutarou Mihara, Takuji Torimura
    A rare case of sarcoidosis in accessory spleen
    A 73-year-old woman with sarcoidosis of the heart, lungs, and eyes had been receiving steroid therapy for 12 years (maintenance dose at prednisolone 5 mg/day) and had undergone pacemaker implantation 4 years earlier for complete atrioventricular block. Fluorodeoxyglucose (FDG) positron emission tomography for scrutiny of cardiac sarcoidosis incidentally revealed abnormal accumulation (FDG maximum standardized uptake value, 4.8) in the pancreatic tail (A), and she was referred to our department on suspicion of pancreatic cancer.


    Date de mise en ligne : Vendredi 26 mai 2017
    Andrea Parodi, Geoffroy Vanbiervliet, Cesare Hassan, Xavier Hebuterne, Antonella De Ceglie, Rosa Angela Filiberti, Cristano Spada, Massimo Conio
    Colon capsule endoscopy to screen for colorectal neoplasia in those with family histories of colorectal cancer
    Colon capsule endoscopy (CCE) has been recognized as an alternative for colorectal cancer (CRC) screening in average-risk people. Our aim was to prospectively assess the accuracy of CCE as a screening tool in first-degree relatives (FDRs) of people with CRC by using optical colonoscopy (OC) with segmental unblinding as the reference standard.


    Date de mise en ligne : Vendredi 26 mai 2017
    Aymeric Becq, Gabriel Rahmi, Guillaume Perrod, Christophe Cellier
    Hemorrhagic angiodysplasia of the digestive tract: pathogenesis, diagnosis, and management
    GI angiodysplasia (GIA) is an acquired vascular superficial lesion, which presents typically as a bright red, irregular, round, slightly elevated lesion. GIAs are often seen in patients aged >60 years and are mostly located in the colon (cecum and ascending colon). The cause and mechanisms of GIA have yet to be completely understood. Small-bowel GIAs often are diagnosed in the setting of obscure GI bleeding. In some cases, GIAs are associated with aortic stenosis, von Willebrand’s disease, chronic renal disease, and liver disease.


    Date de mise en ligne : Vendredi 26 mai 2017
    Daniela Guerrero Vinsard, Mark E. Stark, Jason T. Lewis, Ming-Hsi Wang
    Nonsteroidal anti-inflammatory drug–induced protein-losing enteropathy: a great masquerade of Crohn’s disease
    A 29-year-old woman was referred to our facility because of a 2-year history of relapsing abdominal pain associated with melena, diarrhea, chronic arthralgia, and new onset of lower extremity edema. Previous workup in an outside center included negative results for HLA B-27 testing without radiologic features of spondyloarthropathy. Capsule endoscopy revealed erosions, circular ulcers, and concentric stenosis in the proximal jejunum and ileum (A, B). An abdominal CT scan revealed nonobstructing dilatated and stenotic segments within the ileum (C).


    Date de mise en ligne : Mercredi 24 mai 2017
    Jose Nieto, Huda Khaleel, Youssef Challita, Melissa Jimenez, Todd H. Baron, Laura Walters, Kelli Hathaway, Ketul Patel, Ali Lankarani, Michael Herman, David Holloman, Sammy Saab
    EUS-guided fine-needle core liver biopsy sampling using a novel 19-gauge needle with modified 1-pass, 1 actuation wet suction technique
    EUS-guided fine-needle core biopsy sampling is a safe and effective technique for diagnosis of focal liver lesions. However, data are limited in its role in parenchymal disease. We evaluated the utility of EUS-guided parenchymal liver biopsy sampling with a modified 1-pass wet suction technique (EUS-modified liver biopsy sampling [EUS-MLB]) in patients with unexplained increase in liver-associated tests.


    Date de mise en ligne : Mardi 23 mai 2017
    Sajan Jiv Singh Nagpal, Dhruvika Mukhija, Madhusudhan Sanaka, Rocio Lopez, Carol A. Burke
    Metachronous colon polyps in younger versus older adults: a case-control study
    The incidence of colorectal cancer in the United States has decreased substantially in individuals aged 50 and older. In contrast, it is increasing in young adults. The polyp characteristics on baseline and follow-up colonoscopy in young adults are not well characterized. We describe the polyp characteristics on baseline and follow-up colonoscopy in adults <40 years and determined factors associated with the occurrence of metachronous, advanced neoplasia or high-risk (HR) polyp features. We compared the occurrence of metachronous advanced neoplasia in young adults with those 50 years and older to assess whether postpolypectomy surveillance guidelines seem appropriate for polyp-bearing adults less than age 40 years.


    Date de mise en ligne : Mercredi 17 mai 2017
    Marco Bassi, Carmelo Luigiano, Stefania Ghersi, Carlo Fabbri, Giulia Gibiino, Lucio Balzani, Giuseppe Iabichino, Alberto Tringali, Raffaele Manta, Massimiliano Mutignani, Vincenzo Cennamo
    A multicenter randomized trial comparing the use of touch versus no-touch guidewire technique for deep biliary cannulation: the TNT study
    There are 2 techniques described for selective bile duct guidewire cannulation, the touch (T) technique (engaging the papilla with a sphincterotome and then advancing the guidewire) and the no-touch (NT) technique (engaging the papilla only with the guidewire). The aim of this prospective, multicenter randomized study was to compare the outcomes of the 2 guidewire cannulation techniques.


    Date de mise en ligne : Mercredi 10 mai 2017
    Yoshihito Tanaka, Hiro-o Yamano, Eiichiro Yamamoto, Hiro-o Matushita, Hironori Aoki, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Michiko Nakaoka, Yuko Yoshida, Makoto Eizuka, Tamotsu Sugai, Hiromu Suzuki, Hiroshi Nakase
    Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia
    Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with BRAF mutation and the CpG island methylator phenotype (CIMP), develop cytologic dysplasia (CD) during the progression of colorectal tumorigenesis. In the present study we aimed to clarify the endoscopic and molecular signatures of SSA/Ps, with and without CD.


    Date de mise en ligne : Mercredi 10 mai 2017
    Navin L. Kumar, Guillaume Kugener, Molly L. Perencevich, John R. Saltzman
    The SAFE-T assessment tool: derivation and validation of a web-based application for point-of-care evaluation of gastroenterology fellow performance in colonoscopy
    Attending assessment is a critical part of endoscopic education for gastroenterology fellows. The aim of this study was to develop and validate a concise assessment tool to evaluate real-time fellow performance in colonoscopy administered via a web-based application.


    Date de mise en ligne : Mercredi 10 mai 2017
    Eisuke Ueshima, Mark Schattner, Robin Mendelsohn, Hans Gerdes, Sebastien Monette, Haruyuki Takaki, Jeremy C. Durack, Stephen B. Solomon, Govindarajan Srimathveeravalli
    Transmural ablation of the normal porcine common bile duct with catheter-directed irreversible electroporation is feasible and does not affect duct patency
    The aim of this study was to evaluate the feasibility and early safety of catheter-directed irreversible electroporation (IRE) of the normal common bile duct (CBD) in swine.


    Date de mise en ligne : Mardi 09 mai 2017
    Gene K. Ma, David A. Pegues, Michael L. Kochman, Kevin Alby, Neil O. Fishman, Marianne Saunders, Carolyn Grous, Daniel T. Dempsey, Gregory G. Ginsberg
    Implementation of a systematic culturing program to monitor the efficacy of endoscope reprocessing: outcomes and costs
    In 2015, the U.S. Food and Drug Administration and Centers for Disease Control and Prevention (CDC) issued guidance for duodenoscope culturing and reprocessing in response to outbreaks of carbapenem-resistant Enterobacteriaceae (CRE) duodenoscope-related infections. Based on this guidance, we implemented best practices for reprocessing and developed a systematic process for culturing endoscopes with elevator levers. The aim of this study is to report the outcomes and direct costs of this program.


    Date de mise en ligne : Jeudi 04 mai 2017
    Andreas Oberbach, Nadine Schlichting, Marco Heinrich, Yvonne Kullnick, Ulf Retschlag, Stefanie Lehmann, Mouen A. Khashab, Anthony N. Kalloo, Vivek Kumbhari
    Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats
    The gastric mucosa is an endocrine organ that regulates satiation pathways by expression of orexigenic and anorexigenic hormones. Vertical sleeve gastrectomy (VSG) excludes gastric mucosa and reduces gastric volume. Our study aimed to investigate the independent effects of altering gastric mucosa on obesity and its related comorbidities.


    Date de mise en ligne : Jeudi 04 mai 2017
    Tae Hoon Lee, Tae Hyeon Kim, Jong Ho Moon, Sang Hyub Lee, Hyun Jong Choi, Young Hwangbo, Jong Jin Hyun, Jun-Ho Choi, Seok Jeong, Jong Hyeok Kim, Do Hyun Park, Joung-Ho Han, Sang-Heum Park
    Bilateral versus unilateral placement of metal stents for inoperable high-grade malignant hilar biliary strictures: a multicenter, prospective, randomized study (with video)
    The efficacy of palliative biliary drainage by using bilateral or unilateral self-expandable metal stents (SEMSs) for a malignant hilar biliary stricture (MHS) remains controversial. This prospective, randomized, multicenter study investigated whether bilateral drainage by using SEMSs is superior to unilateral drainage in patients with inoperable MHSs.


    Date de mise en ligne : Mercredi 03 mai 2017
    Froukje B. van Hoeij, Fraukje A. Ponds, Yuki Werner, Joel M. Sternbach, Paul Fockens, Barbara A. Bastiaansen, André J.P.M. Smout, John E. Pandolfino, Thomas Rösch, Albert J. Bredenoord
    Management of recurrent symptoms after per-oral endoscopic myotomy in achalasia
    Per-oral endoscopic myotomy (POEM) has been rapidly gaining ground as a treatment for achalasia. Although POEM is a safe and effective treatment, a subset of patients has persistent or recurrent symptoms after POEM. This study aimed to examine the efficacy of different retreatments after failed POEM.


    Date de mise en ligne : Mercredi 03 mai 2017
    Douglas K. Rex, Prasanna L. Ponugoti, Cynthia S. Johnson, Lisa Kittner, Randy J. Yanda
    Neoplasia at 10-year follow-up screening colonoscopy in a private U.S. practice: comparison of yield to first-time examinations
    Prior studies assessing the yield of a second screening colonoscopy performed 10 years after an initial screening colonoscopy with negative results did not include a control group of persons undergoing a first screening colonoscopy during the same time interval. Our aim was to describe the incidence of neoplasia at a second screening colonoscopy (performed at least 8 years after the first colonoscopy) in average-risk individuals and compare it with the yield of first screening examinations performed during the same time interval.


    Date de mise en ligne : Mercredi 03 mai 2017
    Yun Duk Jung, Woo Chul Chung, Yeon-Ji Kim, Kyong-Hwa Jun, Hyung-Min Chin
    Gastric neuroendocrine tumor mimicking early gastric cancer
    A 55-year-old man visited the gastroenterology department because of an abnormal endoscopic finding on health screening. The patient had no relevant medical history. On endoscopy, a 1.0-cm ovoid, depressed mucosal lesion was observed in the greater curvature side of the lower body (A). It had cutting edges and looked like an early gastric cancer type IIc (B). At pathologic report, a neuroendocrine tumor (NET, G1) was diagnosed (C), and a positive reaction of chromogranin was found. Mitosis was less than 1/10 high-power field, and the Ki-67 index was 1%.


    Date de mise en ligne : Mercredi 03 mai 2017
    Masanori Kobayashi, Ou Yamaguchi, Koji Nagata, Kouichi Nonaka, Shomei Ryozawa
    Acute hemorrhagic gastritis after nivolumab treatment
    A 77-year-old man was admitted with a history of epigastralgia that had lasted for several months and hematemesis. Before admission, nivolumab (3 mg/kg) had been started for epidermal growth factor receptor—mutant metastatic lung cancer in 10 courses over 4 months. After admission, upper endoscopy revealed hemorrhagic gastritis evenly spreading over the entire gastric mucosa with a white coating (A-D). Histologically, there was marked lymphoplasmacytic and neutrophilic infiltration in the fundic gland mucosa.


    Date de mise en ligne : Mercredi 03 mai 2017
    Barham K. Abu Dayyeh, Saurabh Mukewar, Shounak Majumder, Raja Zaghlol, Eric J. Vargas Valls, Fateh Bazerbachi, Michael J. Levy, Todd H. Baron, Christopher J. Gostout, Bret T. Petersen, John Martin, Ferga C. Gleeson, Randall K. Pearson, Suresh T. Chari, Santhi S. Vege, Mark D. Topazian
    Large-caliber metal stents versus plastic stents for the management of pancreatic walled-off necrosis
    Symptomatic pancreatic walled-off necrosis (WON) may be managed by endoscopic transmural drainage and endoscopic transmural necrosectomy, with stent placement at endoscopic drainage sites. The optimal stent choice is yet to be determined. We compared outcomes after endoscopic management of WON using either large-caliber fully covered self-expandable metal stents (LC-SEMSs) or double-pigtail plastic stents (DPPSs).


    Date de mise en ligne : Mardi 02 mai 2017
    Timothy D. Imler, Stuart Sherman, Thomas F. Imperiale, Huiping Xu, Fangqian Ouyang, Christopher Beesley, Charity Hilton, Gregory A. Coté
    Provider-specific quality measurement for ERCP using natural language processing
    Natural language processing (NLP) is an information retrieval technique that has been shown to accurately identify quality measures for colonoscopy. There are no systematic methods by which to track adherence to quality measures for ERCP, the highest risk endoscopic procedure widely used in practice. Our aim was to demonstrate the feasibility of using NLP to measure adherence to ERCP quality indicators across individual providers.


    Date de mise en ligne : Vendredi 28 avril 2017
    Michael Dougherty, Thomas M. Runge, Swathi Eluri, Evan S. Dellon
    Esophageal dilation with either bougie or balloon technique as a treatment for eosinophilic esophagitis: a systematic review and meta-analysis
    Esophageal dilation is a now recognized to be an important therapeutic modality in eosinophilic esophagitis (EoE). We aimed to evaluate the safety of esophageal dilation in EoE, especially regarding perforation risk, and to examine perforation risk by dilator type.


    Date de mise en ligne : Vendredi 28 avril 2017
    Carlos Robles-Medranda, Miguel Puga-Tejada, Jesenia Ospina, Manuel Valero, Hannah Pitanga Lukashok
    Over-the-scope clip in the management of fibrotic esophageal variceal bleeding (with video)
    We report the feasibility and technical success of the over-the-scope clip (OTSC) (Ovesco Endoscopy AG, Tuebingen, Germany) in the mechanical closure of esophageal variceal bleeding (VB) in a cirrhotic patient with variceal wall disruption associated with fibrosis secondary to long-term treatment of endoscopy band ligation (EBL).


    Date de mise en ligne : Vendredi 28 avril 2017
    Eddie Y. Liu, Paul J. Belletrutti
    Isolated esophageal tears from deceleration trauma
    A 30-year-old woman, while snowboarding, fell 15 feet from a jump onto hard-packed snow and sustained soft tissue injuries to her left hip and chest wall. Forty-eight hours later, she experienced retrosternal pleuritic chest pain and progressive odynophagia. An empirical trial with a proton-pump inhibitor (PPI) for 5 days did not resolve her symptoms. Medical evaluation 10 days later revealed unremarkable results of physical examination, no fever, and a normal white blood count. CT of the chest and abdomen showed no abnormalities.


    Date de mise en ligne : Mardi 25 avril 2017
    James P. Moriarty, Nilay D. Shah, Joel H. Rubenstein, Christopher H. Blevins, Michele Johnson, David A. Katzka, Kenneth K. Wang, Louis Michel Wongkeesong, David A. Ahlquist, Prasad G. Iyer
    Costs associated with Barrett’s esophagus screening in the community: an economic analysis of a prospective randomized controlled trial of sedated versus hospital unsedated versus mobile community unsedated endoscopy
    Data on the economic impact associated with screening for Barrett’s esophagus (BE) are limited. As part of a comparative effectiveness randomized trial of unsedated transnasal endoscopy (uTNE) and sedated EGD (sEGD), we assessed costs associated with BE screening.


    Date de mise en ligne : Mardi 25 avril 2017
    Kamar Belghazi, Frederike G.I. van Vilsteren, Bas L.A.M. Weusten, Sybren L. Meijer, Jacques J.G.H.M. Bergman, Roos E. Pouw
    Long-term follow-up results of stepwise radical endoscopic resection for Barrett’s esophagus with early neoplasia
    Stepwise radical endoscopic resection (SRER) has shown to be effective in eradicating Barrett’s esophagus (BE) and its associated dysplasia. The aim of this study was to assess the long-term durability after successful SRER for early Barrett’s neoplasia.


    Date de mise en ligne : Mardi 25 avril 2017
    Rachel S. van der Post, Jolanda van Dieren, Anna Grelack, Nicoline Hoogerbrugge, Lizet E. van der Kolk, Petur Snaebjornsson, Iris Lansdorp-Vogelaar, J. Han van Krieken, Tanya M. Bisseling, Annemieke Cats
    Outcomes of screening gastroscopy in first-degree relatives of patients fulfilling hereditary diffuse gastric cancer criteria
    The aim of this study was to determine the yield of endoscopic screening in first-degree relatives (FDRs) of CDH1-negative hereditary diffuse-type gastric cancer (HDGC) patients.


    Date de mise en ligne : Mardi 25 avril 2017
    Peter B. Cotton, Qi Pauls, Jamila Keith, Andre Thornhill, Douglas Drossman, April Williams, Valerie Durkalski-Mauldin
    The EPISOD study: long-term outcomes
    The EPISOD (Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction) study randomized patients with post-cholecystectomy pain, and little or no objective evidence for biliary obstruction, to sphincterotomy or sham intervention. Results at 1 year showed no benefit for the active treatment. We now report the outcomes at up to 5 years.


    Date de mise en ligne : Mardi 25 avril 2017
    Fernanda Prata Martins, Gustavo Andrade De Paulo, MĂ´nica L.C. Contini, Angelo Paulo Ferrari
    Metal versus plastic stents for anastomotic biliary strictures after liver transplantation: a randomized controlled trial
    Biliary anastomotic stricture occurs in 15% to 20% of patients after deceased orthotopic liver transplantation (OLT). It is usually treated endoscopically with multiple plastic stents (MPSs), although the use of fully covered self-expandable metal stents (cSEMSs) is emerging. This study aims to compare the efficacy and safety of cSEMSs versus MPSs in these patients.


    Date de mise en ligne : Jeudi 20 avril 2017
    Ming Tan, Ove B. Schaffalitzky de Muckadell, Stig B. Laursen
    Association between early ERCP and mortality in patients with acute cholangitis
    Acute cholangitis (AC) is associated with high mortality of up to 10%. The association between timing of ERCP and mortality in patients with AC remains unclear. The aim of this study was to investigate whether early ERCP within 24 hours was associated with improved survival.


    Date de mise en ligne : Mardi 18 avril 2017
    Chen Chen, Christian Stock, Michael Hoffmeister, Hermann Brenner
    Public health impact of colonoscopy use on colorectal cancer mortality in Germany and the United States
    Colonoscopy has been demonstrated to be effective in reducing colorectal cancer (CRC) incidence and mortality and has been widely used for primary CRC screening in Germany and the United States. We performed a population-based analysis to evaluate and compare the public health impact of recent colonoscopy use on CRC deaths among adults aged 55 to 79 years in Germany and the United States from 2008 to 2011.


    Date de mise en ligne : Mardi 18 avril 2017
    Hee Seung Lee, Sung Bae Kim, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim
    Postoperative adjuvant chemotherapy is associated with a lower incidence of colorectal adenomas in patients with previous colorectal cancer
    The effects of chemotherapeutic agents on the development of colorectal adenomas in patients with previous colorectal cancer (CRC) are not defined. Therefore, we evaluated the potential effect of adjuvant chemotherapy on the incidence of colorectal adenomas in patients with previous CRC.


    Date de mise en ligne : Jeudi 13 avril 2017
    Zacharias P. Tsiamoulos, Ravi Misra, Rajaratanam Rameshshanker, Timothy R. Elliott, Iosif Beintaris, Siwan Thomas-Gibson, Adam Haycock, Noriko Suzuki, Colin Rees, Brian P. Saunders
    Impact of a new distal attachment on colonoscopy performance in an academic screening center
    Distal attachments placed on the colonoscope tip may positively affect performance by assisting insertion and polyp detection. The original Endocuff (ARC Medical Design, Leeds, United Kingdom) appears to improve adenoma detection rate (ADR), but no data assess the performance of the second-generation Endocuff Vision.


    Date de mise en ligne : Lundi 10 avril 2017
    Anne F. Peery, Nicholas J. Shaheen, Katherine S. Cools, Todd H. Baron, Mark Koruda, Joseph A. Galanko, Ian S. Grimm
    Morbidity and mortality after surgery for nonmalignant colorectal polyps
    Despite evidence that most nonmalignant colorectal polyps can be managed endoscopically, a substantial proportion of patients with a nonmalignant colorectal polyp are still sent to surgery. Risks associated with this surgery are not well characterized. We describe 30-day postoperative morbidity and mortality and explore risk factors for adverse events in patients undergoing surgical resection for nonmalignant colorectal polyps.


    Date de mise en ligne : Vendredi 07 avril 2017
    Loren Laine, Stig B. Laursen, Harry R. Dalton, Jing H. Ngu, Michael Schultz, Adrian J. Stanley
    Relationship of time to presentation after onset of upper GI bleeding with patient characteristics and outcomes: a prospective study
    We performed a prospective multi-national study of patients presenting to the emergency department with upper GI bleeding (UGIB) and assessed the relationship of time to presentation after onset of UGIB symptoms with patient characteristics and outcomes.


    Date de mise en ligne : Vendredi 07 avril 2017
    Benjamin L. Bick, Thomas F. Imperiale, Cynthia S. Johnson, John M. DeWitt
    Endoscopic suturing of esophageal fully covered self-expanding metal stents reduces rates of stent migration
    Endoscopic suturing of fully covered self-expanding metal stents (FC-SEMSs) may prevent migration. The aim of this study was to compare rates of migration between sutured FC-SEMSs (S-FCSEMSs), unsecured FC-SEMSs, and partially covered SEMSs (PC-SEMSs) placed for benign esophageal leaks and strictures.


    Date de mise en ligne : Vendredi 07 avril 2017
    Nisa Netinatsunton, Jaksin Sottisuporn, Siriboon Attasaranya, Teepawit Witeerungrot, Aroon Siripun, Tanawat Pattarapuntakul, Bancha Ovartlarnporn
    Prospective randomized trial of EUS-assisted ERCP without fluoroscopy versus ERCP in common bile duct stones
    ERCP with stone removal is the standard treatment for common bile duct stones (CBDSs). Radiation exposure is a risk to the endoscopist and patient. EUS-guided ERCP without fluoroscopy (EGEWF) in patients with CBDSs is feasible, but the efficacy and safety compared with ERCP is unknown. We aimed to compare the efficacy and safety of EGEWF with ERCP in CBDS removal.


    Date de mise en ligne : Vendredi 07 avril 2017
    Ye Han, Jintao Guo, Siyu Sun, Weichao Wu, Sheng Wang, Nan Ge, Xiang Liu, Guoxin Wang, Shupeng Wang
    Acellular dermal matrix for esophageal stricture prevention after endoscopic submucosal dissection in a porcine model
    Endoscopic submucosal dissection (ESD) is considered an effective treatment for early esophageal cancer and precancerous lesions. Esophageal stenosis is closely associated with quasi-circumferential ESD. We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane.


    Date de mise en ligne : Jeudi 06 avril 2017
    Sung Yong Han, Gwang Ha Kim
    Collision tumor arising from a gastric duplication cyst
    A 41-year-old woman presented with a gastric subepithelial lesion. Upper endoscopy revealed a 6-cm subepithelial mass with surface erosions at the posterior wall of the upper body of the stomach (A). Endoscopic ultrasonography revealed a homogenous cystic lesion with inner mucus debris and a solid mass in the periphery, which invaded the pancreatic tail (B, arrow). Total gastrectomy and distal pancreatectomy were performed. The cyst was located in the muscularis propria of the stomach (C, arrowhead), and a histopathologic examination showed that the cystic space was lined by columnar or squamous epithelial mucosa.


    Date de mise en ligne : Jeudi 06 avril 2017
    Yasser Shaib, Lara Hassoun
    Double-lumen duodenum
    A 33-year-old man with a history of Hodgkin lymphoma was seen 92 days after allogenic stem cell transplantation; he presented with a 5-day history of large-volume watery diarrhea. The results of laboratory evaluation and stool studies were noncontributory. Flexible sigmoidoscopy with examination of biopsy specimens revealed mild chronic colitis with no evidence of graft-versus-host disease (GVHD). Nevertheless, the patient was given systemic and nonabsorbable steroid agents. However, he continued to have large-volume diarrhea, worsening anorexia, and malnutrition.


    Date de mise en ligne : Mardi 04 avril 2017
    Antonio D’Antonio, Patrizia Borgheresi, Maria Addesso
    An unexpected adverse event of gastric bypass: giant hyperplastic polyp showing an intramucosal adenocarcinoma
    A 58-year-old woman underwent a gastroscopy for iron deficiency anemia, epigastric pain, outlet obstruction, and abdominal distension. The patient had undergone open gastric bypass 4 years earlier because of morbid obesity. The gastroscopy showed a pedunculated 8-cm polyp with a thick stalk on the anterior wall of the antrum (A). The polyp surface appeared composed of multiple villous-like projections with a smooth surface (B). Examination of repeated biopsy specimens from the polypoid lesion showed a hyperplastic polyp.


    Date de mise en ligne : Mardi 04 avril 2017
    Douglas G. Adler
    Use of a lumen-apposing metal stent to treat pyloric stenosis
    A 77-year-old woman with a 100 pack/year history of tobacco use presented to our center with failure to thrive, weight loss, and intolerance of oral intake. Chest, abdominal, and pelvic CT revealed multiple lung masses and liver metastases. Examination of a biopsy specimen from her lung mass revealed squamous cell carcinoma of the lung. A positron emission tomography scan did not show hypermetabolic activity at the pylorus. An EGD was performed to investigate her eating issues and revealed a high-grade stenosis of her pylorus with an overall benign appearance suggestive of scarring secondary to prior peptic ulcer disease (A).


    Date de mise en ligne : Mardi 04 avril 2017
    Harry D.S. Soar, Muhammad H. Shiwani
    Successful endoscopic removal of a telescopic radio aerial from the stomach
    Ingestion of a foreign body is a common reason for attendance at the emergency department. Each case provides a unique challenge depending on the size, shape, and consistency of the object swallowed. We present a challenging case of a rarely ingested and unusually shaped object: a telescopic radio aerial and the techniques we used to successfully manage it. A 23-year-old woman from a local psychiatric hospital had swallowed a biro pen and a metal telescopic radio aerial that she had broken off from an FM radio.


    Date de mise en ligne : Lundi 03 avril 2017
    Luis F. Lara, Morihito Takita, James S. Burdick, Daniel C. DeMarco, Ronnie R. Pimentel, Tolga Erim, Marlon F. Levy
    A study of the clinical utility of a 20-minute secretin-stimulated endoscopic pancreas function test and performance according to clinical variables
    Direct pancreas juice testing of bicarbonate, lipase, or trypsin after stimulation by secretin or cholecystokinin is used to determine exocrine function, a surrogate for diagnosing chronic pancreatitis (CP). Endoscopic pancreas function tests (ePFTs), where a peak bicarbonate concentration (PBC) ≥80 mEq/L in pancreas juice is considered normal, are now used more frequently. In this ePFT, aspirates start 35 minutes after secretin administration because pancreas output peaks 30 minutes after secretagogue administration.


    Date de mise en ligne : Lundi 03 avril 2017
    Yoon Suk Jung, Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn
    Colorectal cancer screening with the fecal immunochemical test in persons aged 30 to 49 years: focusing on the age for commencing screening
    The fecal immunochemical test (FIT) can be an alternative screening method for colorectal cancer in individuals aged <50 years. However, debate continues concerning the age at which commencing FIT is beneficial.


    Date de mise en ligne : Samedi 01 avril 2017
    Navin L. Kumar, Brian L. Claggett, Aaron J. Cohen, Jennifer Nayor, John R. Saltzman
    Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding
    An increase in blood urea nitrogen (BUN) at 24 hours is a solitary and significant predictor of mortality in patients with acute pancreatitis, which may predict worse outcomes in the similarly resuscitation-requiring condition of acute nonvariceal upper GI bleeding (UGIB). The aim of our study was to assess whether an increase in BUN at 24 hours is predictive of worse clinical outcomes in acute nonvariceal UGIB.


    Date de mise en ligne : Jeudi 30 mars 2017
    Peter B. Cotton, Derek Feussner, Darin Dufault, Gregory Cote
    A survey of credentialing for ERCP in the United States
    There are limited data measuring the variability in standards used by hospitals for credentialing physicians to ERCP in the United States.


    Date de mise en ligne : Jeudi 30 mars 2017
    Samir C. Grover, Michael A. Scaffidi, Rishad Khan, Ankit Garg, Ahmed Al-Mazroui, Tareq Alomani, Jeffrey J. Yu, Ian S. Plener, Mohamed Al-Awamy, Elaine L. Yong, Maria Cino, Nikila C. Ravindran, Mark Zasowski, Teodor P. Grantcharov, Catharine M. Walsh
    Progressive learning in endoscopy simulation training improves clinical performance: a blinded randomized trial
    A structured comprehensive curriculum (SCC) that uses simulation-based training (SBT) can improve clinical colonoscopy performance. This curriculum may be enhanced through the application of progressive learning, a training strategy centered on incrementally challenging learners. We aimed to determine whether a progressive learning-based curriculum (PLC) would lead to superior clinical performance compared with an SCC.


    Date de mise en ligne : Jeudi 30 mars 2017
    James L. Buxbaum, David Hormozdi, Mario Dinis-Ribeiro, Christianne Lane, Diogo Dias-Silva, Ara Sahakian, Preeth Jayaram, Pedro Pimentel-Nunes, Daniel Shue, Michael Pepper, Daniel Cho, Loren Laine
    Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial
    Gastric intestinal metaplasia (GIM) is a gastric cancer precursor. Narrow-band imaging (NBI) may improve detection of GIM. We compared detection of GIM with high-definition white-light (HD-WL) endoscopy, NBI, and mapping biopsies in a population with increased gastric cancer risk.


    Date de mise en ligne : Mercredi 29 mars 2017
    Enqiang Linghu, Chen Du, Ningli Chai, Huikai Li, Zhiqiang Wang, Yufa Sun, Wei Xu, Xu Guo, Bo Ning, Lihua Sun, Wei Zhang, Xiangdong Wang, Ping Tang, Jia Feng
    A prospective study on the safety and effectiveness of using lauromacrogol for ablation of pancreatic cystic neoplasms with the aid of EUS
    With the development of imaging techniques, the detection rate of pancreatic cystic neoplasms (PCNs) has increased. The surgical morbidity and mortality rates of PCNs are quite high. This study is intended to evaluate the safety and effectiveness of a minimally invasive treatment, EUS-guided PCN ablation with lauromacrogol.


    Date de mise en ligne : Samedi 18 mars 2017
    Marietta Iacucci, Marco Daperno, Mark Lazarev, Razvan Arsenascu, Gian Eugenio Tontini, Oluseyi Akinola, Xianyong Sean Gui, Vincenzo Villanacci, Martin Goetz, Mark Lowerison, Brendan Cord Lethebe, Maurizio Vecchi, Helmut Neumann, Subrata Ghosh, Raf Bisschops, Ralf Kiesslich
    Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis
    Endoscopic inflammation and healing are important therapeutic endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual chromoendoscopy (EVC) score that could reflect the full spectrum of mucosal and vascular changes including mucosal healing in UC.


    Date de mise en ligne : Samedi 18 mars 2017
    Anne-Fré Swager, Fons van der Sommen, Sander R. Klomp, Sveta Zinger, Sybren L. Meijer, Erik J. Schoon, Jacques J.G.H.M. Bergman, Peter H. de With, Wouter L. Curvers
    Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy
    Volumetric laser endomicroscopy (VLE) is an advanced imaging system that provides a near-microscopic resolution scan of the esophageal wall layers up to 3-mm deep. VLE has the potential to improve detection of early neoplasia in Barrett’s esophagus (BE). However, interpretation of VLE images is complex because of the large amount of data that need to be interpreted in real time. The aim of this study was to investigate the feasibility of a computer algorithm to identify early BE neoplasia on ex vivo VLE images.


    Date de mise en ligne : Lundi 13 mars 2017
    Andrea Oliver Tal, Fabian Finkelmeier, Natalie Filmann, Leena Kylänpää, Marianne Udd, Ilaria Parzanese, Paolo Cantù, Alexander Dechêne, Volker Penndorf, Andreas Schnitzbauer, Mireen Friedrich-Rust, Stefan Zeuzem, Jörg G. Albert
    Multiple plastic stents versus covered metal stent for treatment of anastomotic biliary strictures after liver transplantation: a prospective, randomized, multicenter trial
    Treatment of anastomotic biliary strictures (ABSs) after orthotopic liver transplantation by endoscopic insertion of multiple plastic stents (MPSs) is well established. The use of covered self-expandable metal stents (cSEMSs) for this indication is less investigated.


    Date de mise en ligne : Vendredi 10 mars 2017
    Hae Won Kim, Jie-Hyun Kim, Jun Chul Park, Mi Young Jeon, Yong Chan Lee, Sang Kil Lee, Sung Kwan Shin, Hyun Soo Chung, Sung Hoon Noh, Jong Won Kim, Seung Ho Choi, Jae Jun Park, Young Hoon Youn, Hyojin Park
    Additive endoscopic resection may be sufficient for patients with a positive lateral margin after endoscopic resection of early gastric cancer
    No well-established treatment strategies exist for lateral margin positivity (LM+) alone after endoscopic resection (ER) of early gastric cancer (EGC). Thus, we aimed to clarify a treatment strategy for non-curative resection (non-CR) with LM+ alone after ER in EGC.


    Date de mise en ligne : Vendredi 10 mars 2017
    Wenjie Liu, Min Wang, Lili Zhao, Min Wang, Xiang Wang, Zhining Fan, Li Liu
    Thermo-sensitive isopentane aerification for mucosal lift during endoscopic resection in animal models (with video)
    Mucosal lift is critical for successful endoscopic treatment. Normal saline (NS) solution is widely used as the submucosal filler, but its short persistency restricts clinical endoscopic submucosal dissection (ESD). In this study, thermo-sensitive isopentane was introduced for submucosal injection. With a boiling point at 27.8°C, liquid isopentane can be easily applied, and gasification inflation can provide great support for submucosal lifting at body temperature. The feasibility and efficiency of isopentane were evaluated in this study.


    Date de mise en ligne : Jeudi 09 mars 2017
    Min Min, Pei Deng, Wenhua Zhang, Xiaomin Sun, Yan Liu, Bing Nong
    Comparison of linked color imaging and white-light colonoscopy for detection of colorectal polyps: a multicenter, randomized, crossover trial
    Linked color imaging (LCI), a recently developed technology, uses a laser endoscopic system to enhance the color separation of red color to depict red and white colors more vividly. The benefits of LCI in the detection of colorectal polyps remain unknown. The aim of this study was to assess the ability of LCI to improve the detection of colorectal polyps compared with white-light (WL) endoscopy.


    Date de mise en ligne : Jeudi 09 mars 2017
    Somashekar G. Krishna, William R. Brugge, John M. Dewitt, Pradermchai Kongkam, Bertrand Napoleon, Carlos Robles-Medranda, Damien Tan, Samer El-Dika, Sean McCarthy, Jon Walker, Mary E. Dillhoff, Andrei Manilchuk, Carl Schmidt, Benjamin Swanson, Zarine K. Shah, Phil A. Hart, Darwin L. Conwell
    Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos)
    EUS-guided needle-based confocal laser endomicroscopy (nCLE) characteristics of common types of pancreatic cystic lesions (PCLs) have been identified; however, surgical histopathology was available in a minority of cases. We sought to assess the performance characteristics of EUS nCLE for differentiating mucinous from non-mucinous PCLs in a larger series of patients with a definitive diagnosis.


    Date de mise en ligne : Jeudi 09 mars 2017
    Rui Huang, Hongwei Cai, Xin Zhao, Xiaoqiang Lu, Min Liu, Wenhao Lv, Zhiguo Liu, Kaichun Wu, Ying Han
    Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma: a propensity score matching analysis
    Esophageal endoscopic submucosal dissection (ESD) is technically challenging because of the thinner wall and narrow lumen. The tunnel technique was proposed previously. This current retrospective study aimed to evaluate the efficacy of the tunnel technique in ESD of superficial esophageal squamous cell carcinoma (ESCC).


    Date de mise en ligne : Mercredi 08 mars 2017
    Orly Sneh Arbib, Valentina Zemser, Yaara Leibovici Weissman, Rachel Gingold-Belfer, Alex Vilkin, Sapir Eizenstein, Arnon Cohen, Doron Comaneshter, Shochat Tzipora, Yaron Niv, Yeuda Ringel, David Lieberman, Zohar Levi
    Risk of advanced lesions at the first follow-up colonoscopy after polypectomy of diminutive versus small adenomatous polyps of low-grade dysplasia
    The current guidelines for surveillance after polypectomy do not distinguish between diminutive (1-5 mm) and small (6-9 mm) polyps with low-grade dysplasia (LGD). We aimed to evaluate the risk for advanced neoplasia on follow-up colonoscopy.


    Date de mise en ligne : Mercredi 01 mars 2017
    Markus Dollhopf, Alberto Larghi, Uwe Will, Mihai RimbaĹź, Andrea Anderloni, Andres Sanchez-Yague, Anthony Yuen Bun Teoh, Rastislav Kunda
    EUS-guided gallbladder drainage in patients with acute cholecystitis and high surgical risk using an electrocautery-enhanced lumen-apposing metal stent device
    In high-risk surgical patients, the treatment of choice of acute cholecystitis is percutaneous transhepatic gallbladder drainage (PTGBD). Recently, a novel endoscopic device containing a lumen-apposing metal stent with an electrocautery (ECE-LAMS) on the tip has been developed.


    Date de mise en ligne : Mercredi 01 mars 2017
    Masaya Suenaga, Yoshihiko Sadakari, Jose Alejandro Almario, Michael Borges, Anne-Marie Lennon, Eun-Ji Shin, Marcia Irene Canto, Michael Goggins
    Using an endoscopic distal cap to collect pancreatic fluid from the ampulla (with video)
    Duodenal collections of pancreatic fluid can be used as a source of mutations and other markers of pancreatic ductal neoplasia, but admixing pancreatic juice with duodenal contents lowers the concentrations of mutations. Collecting pancreatic fluid directly from the ampulla could yield a purer sample of pancreatic fluid.


    Date de mise en ligne : Mardi 28 février 2017
    Laith H. Jamil, Amir Kashani, Neiveen Peter, Simon K. Lo
    Safety and efficacy of cap-assisted EMR for sporadic nonampullary duodenal adenomas
    Eradication of sporadic nonampullary duodenal adenomas (SNADAs) is essential because of their high rate of malignant transformation. EMR techniques are the alternative to the traditional surgical treatments of SNADAs. There are very limited data on the safety and efficacy of cap-assisted EMR (C-EMR) in the treatment of SNADA.


    Date de mise en ligne : Mardi 28 février 2017
    Kyoku Sumimoto, Shinji Tanaka, Kenjiro Shigita, Nana Hayashi, Daiki Hirano, Yuzuru Tamaru, Yuki Ninomiya, Shiro Oka, Koji Arihiro, Fumio Shimamoto, Masaharu Yoshihara, Kazuaki Chayama
    Diagnostic performance of Japan NBI Expert Team classification for differentiation among noninvasive, superficially invasive, and deeply invasive colorectal neoplasia
    The Japan NBI Expert Team (JNET) classification is the first universal narrow-band imaging magnifying endoscopic classification of colorectal tumors. Considering each type in this classification, the diagnostic ability of Type 2B is the weakest. Generally, clinical behavior is believed to be different in each gross type of colorectal tumor. We evaluated the differences in the diagnostic performance of JNET classification for each gross type (polypoid and superficial) and examined whether the diagnostic performance of Type 2B could be improved by subtyping.


    Date de mise en ligne : Mardi 21 février 2017
    Yen-I Chen, Haruhiro Inoue, Michael Ujiki, Peter V. Draganov, Paul Colavita, Francois Mion, John Romanelli, Philip Chiu, Valerio Balassone, Lava Patel, Ali Abbas, Dennis Yang, Christy Dunst, Mathieu Pioche, Sabine Roman, JĂ©rĂ´me Rivory, Thierry Ponchon, David Desilets, Roberta Maselli, Manabu Onimaru, Jun Nakamura, Yoshitaka Hata, Gulara Hajiyeva, Amr Ismail, Saowanee Ngamruengphong, Majidah Bukhari, Yamile Haito Chavez, Vivek Kumbhari, Alessandro Repici, Mouen A. Khashab
    An international multicenter study evaluating the clinical efficacy and safety of per-oral endoscopic myotomy in octogenarians
    Per-oral endoscopic myotomy (POEM) for achalasia is particularly appealing in the elderly because it is minimally invasive. However, data in patients aged ≥80 years are scarce. The aim of this study was to assess the clinical outcome of POEM in octogenarians.


    Date de mise en ligne : Mardi 21 février 2017
    Fariha H. Ramay, Qingping Cui, Bruce D. Greenwald
    Outcomes after liquid nitrogen spray cryotherapy in Barrett's esophagus–associated high-grade dysplasia and intramucosal adenocarcinoma: 5-year follow-up
    Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett’s esophagus (BE)–associated high-grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking.


    Date de mise en ligne : Vendredi 10 février 2017
    Takuto Suzuki, Taro Hara, Yoshiyasu Kitagawa, Hideyuki Takashiro, Rino Nankinzan, Osamu Sugita, Taketo Yamaguchi
    Linked-color imaging improves endoscopic visibility of colorectal nongranular flat lesions
    As a newly developed image-enhanced endoscopy (IEE) technique, linked-color imaging (LCI) provides very bright images with enhanced color tones. With the objective of improving the detection rate of colorectal flat tumor lesions, which are difficult to detect, we examined the usefulness of LCI from the viewpoint of visibility.


    Date de mise en ligne : Mardi 07 février 2017
    Wouter F.W. Kappelle, Ronald L.A.W. Bleys, Albert J.M. van Wijck, Peter D. Siersema, Frank P. Vleggaar
    EUS-guided celiac ganglia neurolysis: a clinical and human cadaver study (with video)
    There is little evidence that structures targeted during EUS-guided celiac ganglia neurolysis (EUS-CGN) are celiac ganglia and that selective ethanol injection into ganglia is feasible. We aimed to visualize celiac ganglia, confirm that these structures are ganglia, and visualize ethanol spread after EUS-CGN and EUS-guided celiac plexus neurolysis (EUS-CPN).


    Date de mise en ligne : Mardi 07 février 2017
    Ankie Reumkens, Ad A. Masclee, Bjorn Winkens, Cees T. van Deursen, Silvia Sanduleanu, Christine M. Bakker
    Prevalence of hypokalemia before and after bowel preparation for colonoscopy in high-risk patients
    Bowel preparation for colonoscopy should not cause significant shifts in systemic electrolyte concentrations. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal consequences, prompting us to conduct a study to explore the magnitude of and risk factors for hypokalemia associated with bowel preparation. We paid specific attention to higher-risk subgroups, in particular, diuretic users, hospitalized patients, and patients estimated to be at high risk by the gastroenterologist.


    Date de mise en ligne : Samedi 04 février 2017
    Tannaz Guivatchian, Erika S. Koeppe, Jason R. Baker, Cristina Moisa, Matthew Demerath, Caitlin Foor-Pessin, William D. Chey, Shanti L. Eswaran, Joseph C. Kolars, Stacy B. Menees, Michael Rajala, Michael D. Rice, Rafat Rizk, Joel H. Rubenstein, Pratima Sharma, Andrea Todisco, Elena M. Stoffel
    Family history in colonoscopy patients: feasibility and performance of electronic and paper-based surveys for colorectal cancer risk assessment in the outpatient setting
    Family history is crucial in stratifying patients’ risk for colorectal cancer (CRC). Previous risk assessment tools developed for use in clinic or endoscopy settings have demonstrated suboptimal specificity for identifying patients with hereditary cancer syndromes. Our aim was to test the feasibility and performance of 2 family history surveys (paper and electronic) in individuals presenting for outpatient colonoscopy.


    Date de mise en ligne : Mardi 31 janvier 2017
    Hamita Sachar, Nipaporn Pichetshote, Kavitha Nandigam, Keta Vaidya, Loren Laine
    Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial
    Current guidelines recommend diphenhydramine in patients undergoing endoscopy who are not adequately sedated with a benzodiazepine and opioid combination. Because this practice has not been adequately assessed, we performed a randomized, double-blind trial comparing diphenhydramine with continued midazolam in such patients.


    Date de mise en ligne : Mardi 31 janvier 2017
    Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft-Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
    Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST)
    Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett’s neoplasia and has advantages over conventional EMR in that it enables en-bloc resection and accurate histopathologic analysis of cancer resection margins. However, its long learning curve and higher adverse event rate have tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett’s neoplasia. The primary endpoint was the en-bloc and R0 resection rate.


    Date de mise en ligne : Lundi 30 janvier 2017
    Zibing Woodward, Zaida Rodriguez, Janice H. Jou, Kian Keyashian, Yiyi Chen, Charles R. Thomas, Grace H. Elta, Sharlene L. D’Souza
    Gender disparities in gastroenterology fellowship director positions in the United States
    Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims to determine whether this trend exists in 3-year gastroenterology fellowships in the United States and to evaluate for any factors that may affect these differences.


    Date de mise en ligne : Lundi 09 janvier 2017
    Giovanni D. De Palma, Mariano C. Giglio, Dario Bruzzese, Nicola Gennarelli, Francesco Maione, Saverio Siciliano, Benedetta Manzo, Gianluca Cassese, Gaetano Luglio
    Cap cuff–assisted colonoscopy versus standard colonoscopy for adenoma detection: a randomized back-to-back study
    EndoCuff is a disposable device applied to standard colonoscopes to improve mucosal visualization. Randomized parallel trials have shown that EndoCuff increases the adenoma detection rate (ADR). The primary aim of this study was to compare the ADR between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopies within a randomized back-to-back trial.


    Date de mise en ligne : Lundi 26 septembre 2016
    Dennis Yang, Roxana M. Coman, Michel Kahaleh, Irving Waxman, Andrew Y. Wang, Amrita Sethi, Ashish R. Shah, Peter V. Draganov
    Endoscopic submucosal dissection for Barrett’s early neoplasia: a multicenter study in the United States
    The role of endoscopic submucosal dissection (ESD) in Barrett’s early neoplasia is not well defined, with most studies originating from Asia and Europe. We aimed to assess the efficacy, safety, and results of ESD in Barrett’s esophagus (BE) with high-grade dysplasia (HGD) and early adenocarcinoma (EAC) across centers in the United States.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Information for readers


    Date de mise en ligne : Jeudi 01 janvier 1970
    In upcoming issues...


    Date de mise en ligne : Jeudi 01 janvier 1970
    ASGE update


    Date de mise en ligne : Jeudi 01 janvier 1970
    Focus on...


    Date de mise en ligne : Jeudi 01 janvier 1970
    Editors


    Date de mise en ligne : Jeudi 01 janvier 1970
    Contents


    Date de mise en ligne : Jeudi 01 janvier 1970
    James Buxbaum, Karthik Ravi, William Ross, Brian Weston, Prasad G. Iyer, Amit Rastogi, Michael B. Wallace
    Continuing Medical Education Exam: October 2017


    Date de mise en ligne : Jeudi 01 janvier 1970
    George Triadafilopoulos, Glenn Eisen, Michael B. Wallace
    In Memoriam: Lauren Battat Gerson, MD, MS
    Dr. Lauren Battat Gerson passed away July 21, 2017 after a battle with melanoma. It is always with deep sadness that we mourn the loss of colleague but especially so when we lose someone in the pinnacle of their life.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Sachin Wani, Robert Sedlack, John Dewitt, Kenneth McQuaid, Karen L. Woods
    Response:
    We thank Dr Jones et al1 for their interest and comments in their letter to the editor regarding our recent document, the American Society for Gastrointestinal Endoscopy (ASGE) guidelines for privileging, credentialing, and proctoring to perform GI endoscopy.2 We also thank the Journal for the opportunity to respond to the issues raised in this letter and offer the following responses.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Karen Hartery, Garret Cullen, Hugh E. Mulcahy
    Response:
    We thank Dr Tringali and colleagues1 for their interest in our article, “Covered self-expanding metal stents for the management of common bile duct stones.”2 It provides further evidence that biliary stenting not only ensures biliary drainage but also aids in stone extraction. Their 6 cases add to the 5 retrospective series (including Hartery et al2) and a single case report, including a total of 160 patients, currently published reporting common bile duct (CBD) stone clearance rates varying from 82% to 95% in patients from whom the stent was removed (Table 1).


    Date de mise en ligne : Jeudi 01 janvier 1970
    Daniel B. Jones, John G. Hunter, Courtney M. Townsend, Rebecca M. Minter, Patricia L. Roberts, Stacy Brethauer, Nathaniel J. Soper
    SAGES rebuttal
    We read with disappointment the updated “Guidelines for privileging, credentialing, and proctoring to perform GI endoscopy” authored by the American Society for Gastrointestinal Endoscopy (ASGE) Standards of Practice Committee and have major concerns regarding inconsistencies in the recommendations.1 Having recently published similar guideline recommendations from the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES),2 we offer the following observations on this important topic.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Badr Al-Bawardy, Elizabeth Rajan, Louis M. Wong Kee Song
    Response:
    We thank Coman et al1 for their letter and interest in our article “Over-the-scope clip-assisted endoscopic full-thickness resection of epithelial and subepithelial GI lesions.” They describe a case of delayed gastric perforation in a patient with gastroparesis after undergoing over-the-scope-clip (OTSC)-assisted full-thickness biopsy. This case highlights that advanced resection techniques, such as OTSC-assisted endoscopic full-thickness resection (EFTR), are associated with procedure-related risks, and close postprocedural monitoring is essential to detect and promptly manage adverse events.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Hassan Siddiki, Norio Fukami
    Endoscopic submucosal dissection for Barrett’s neoplasia: decade of experience, little progress. Is ESD thE-BEST for complex Barrett’s neoplasia?
    The most recent American College of Gastroenterology (ACG) and American Society for Gastrointestinal Endoscopy (ASGE) guideline on Barrett’s esophagus1,2 recommends endoscopic eradication therapy as the procedure of choice for patients with high-grade dysplasia (HGD) or intramucosal carcinoma (IMC).


    Date de mise en ligne : Jeudi 01 janvier 1970
    Sarah K. McGill, Roy Soetikno, Tonya Kaltenbach
    Optical diagnosis of early colorectal cancer: riding the highs and lows of the Japanese Narrow-Band Imaging Expert Team classification
    Recent initiatives in the optical diagnosis of colorectal polyps have the potential to improve our management of neoplasia found at colonoscopy. If endoscopists can predict histologic features with high accuracy, they could resect and discard diminutive adenomas without pathologic evaluation and save costs. They potentially could leave in situ diminutive hyperplastic polyps of the rectosigmoid colon that do not have malignant potential.1 They could ensure careful en bloc endoscopic resection for polyps with advanced pathologic features that have not deeply invaded the submucosa.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Yen-I Chen, Mouen A. Khashab
    Response:
    We thank Matsushita and colleagues1 for their comments regarding our report comparing EUS-guided pancreatic duct drainage (EUS-PDD) with enteroscopy-assisted endoscopic retrograde pancreatography (e-ERP) in post-Whipple anatomy.2 Pancreaticojejunostomy (PJ) adverse events after Whipple surgery such as anastomotic stricture, pancreatic fistula, and recurrent pancreatitis are common and are associated with significant morbidity.3-5 E-ERP in this patient population is difficult, and the technical success rates have been shown to be as low as 8% in expert hands.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Gautam Mankaney, Carol A. Burke
    Risk of metachronous advanced neoplasia in patients with diminutive versus small tubular adenomas: Is the juice worth the squeeze?
    One major goal of colonoscopy is to prevent death resulting from colorectal cancer. Colorectal cancer mortality is reduced by the use of screening colonoscopy1 and colonoscopy with polypectomy.2-4 The performance of colonoscopy and its protective benefit on colorectal cancer has been shown to vary according to several factors, including the specialty of the endoscopist, quality of bowel preparation, completeness of examination, adenoma detection rate (ADR), and effectiveness of polypectomy, to name a few.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Roxana M. Coman, Dennis Yang, Peter V. Draganov
    Endoscopic full-thickness resection with use of the over-the-scope clip: a word of caution!
    In the recent article “Over-the-scope clip-assisted endoscopic full-thickness resection of epithelial and subepithelial GI lesions.” by Al-Bawardy et al,1 the authors describe an elegant and simple approach in obtaining endoscopic full-thickness resection (EFTR) using the over-the-scope clip (OTSC) for both definitive diagnosis and potential curative treatment of lesions involving any layer of the GI wall. In that case series, there were no reported adverse events. Similarly, several other case series describing the use of OTSCs reported no adverse events.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Joel E. Richter
    Esophageal dilation for eosinophilic esophagitis: it’s safe! Why aren’t we doing more dilations?
    Eosinophilic esophagitis (EoE) was first recognized as an inflammatory disease of the esophagus with mucosal eosinophilia, but over the past 10 years it has been slowly realized that esophageal remodeling with stricture disease is an important feature, especially in adult patients. Esophageal strictures are present in 30% to 80% of adults with EoE.1 Several studies confirm that the presence and severity of stricture disease coincides with the longer duration of undiagnosed disease.1,2 In this latter stage, proton pump inhibitors (PPIs), topical steroids, dietary therapy, or a combination of these measures may improve any ongoing inflammation, but symptoms often persist until the fibrostenosis is disrupted by esophageal dilation.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Mitsunobu Matsushita, Masanori Koyabu, Akiyoshi Nishio, Toshihito Seki, Kazuichi Okazaki
    Techniques of ERCP with a conventional endoscope in pancreatoduodenectomy anatomy
    We read with interest the article by Chen et al1 on the study comparing EUS-guided pancreatic duct drainage (EUS-PDD) with enteroscopy-assisted endoscopic retrograde pancreatography (e-ERP) in pancreatoduodenectomy anatomy. Technical success was achieved in 92.5% of cases (EUS-PDD) and 20% of cases (e-ERP) (P < .001). In e-ERP, the reasons for technical failure included failed cannulation (42.9%), inability to identify the pancreatojejunostomy (35.7%), and inability to reach the pancreatojejunostomy (21.4%).


    Date de mise en ligne : Jeudi 01 janvier 1970
    Hazem Hammad, Tonya Kaltenbach, Roy Soetikno
    Image-enhanced endoscopy: How far do we need to go?
    Flat tumors and laterally spreading tumors (LSTs) have greater malignant potential than polypoid lesions and are harder to detect during colonoscopy.1,2 Yet, their detection and detection of sessile serrated polyps (SSPs) continue to be a challenge. Tandem colonoscopy studies showed that 1 in 4 adenomas (particularly flat ones) could be missed during colonoscopy.3 When missed, they can lead to cancers. Close to 60% of postcolonoscopy colorectal cancers were attributed to missed lesions during prior colonoscopy.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Alberto Tringali, Marcello Cintolo, Massimiliano Mutignani
    Do we really need a fully covered self-expanding metal stent for the treatment of difficult common bile duct stones?
    We read with interest the article by Hartery et al1 about the use of fully covered self-expanding metal stents (FCSEMSs) in the management of common bile duct (CDB) stones. Approximately 85% to 90% of bile duct stones can be extracted by use of a retrieval basket or balloon catheter after endoscopic sphincterotomy (EST),2 but 10% to 15% of stones may be difficult to remove.3 In those cases. treatment includes endoscopic papillary balloon dilation,4 fragmentation by use of mechanical lithotripsy (ML),5 electrohydraulic lithotripsy,6 extracorporeal lithotripsy, or laser lithotripsy.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Cesare Hassan, Gianluigi Condorelli, Alessandro Repici
    Bowel preparation for colonoscopy and hypokalemia: at the heart of the problem!
    Colonoscopy has quickly become the preferred primary test for colorectal cancer (CRC) screening in the United States,1 and it is also extensively used for the same indication or similar indications (ie, workup after a positive fecal test result) in Europe.2 The success of colonoscopy is mainly explained by its high accuracy in detecting (advanced) neoplasia, which in turn has been related to a remarkable degree of CRC incidence and mortality prevention.3,4 In addition, the strict association between quality of the colonoscopy and the risk of postcolonoscopy cancer has prompted strategies to maximize the performance of the endoscopist in terms of detection, to minimize the risk of postcolonoscopy interval cancer.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Koushik K. Das, Gary W. Falk
    Long-term outcomes for cryotherapy in Barrett’s esophagus with high-grade dysplasia: just cracking the ice
    Although the progression from Barrett’s esophagus (BE) to esophageal adenocarcinoma (EAC) is well established, it has been increasingly recognized that there is an overall low frequency of this progression in the absence of dysplasia.1 Indeed, multiple, large population–based cohorts have demonstrated that the annual incidence of EAC in BE without dysplasia is 0.1% to 0.3% per year.1,2 In sharp contrast, the annual risk of progression to EAC in patients with high-grade dysplasia (HGD) is estimated at 6%.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Anand V. Sahai
    EUS-guided celiac ganglia neurolysis versus celiac plexus neurolysis: dying to know which is better
    In this issue of Gastrointestinal Endoscopy, Kapelle et al1 took on the daunting task of finding out what actually happens during attempted EUS-guided celiac plexus neurolysis (CPN) and EUS-guided ganglia neurolysis (CGN) in a cadaver model. In the former, the neurolytic agent is injected around the ganglia, whereas in the latter, it is injected in the ganglia.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Prasad G. Iyer
    Endoscopic submucosal dissection in endotherapy for Barrett’s esophagus–related dysplasia and neoplasia: An essential or optional technique?
    Endotherapy for dysplasia or neoplasia arising in Barrett’s esophagus (BE) is now established as the standard of care, being recommended by several gastroenterology society guidelines.1,2 The cornerstones of this strategy are as follows: (1) endoscopic resection to remove visible lesions, which serves to provide accurate histologic staging (distinguishing dysplasia and mucosal adenocarcinoma [EAC] from submucosal adenocarcinoma) and prognostic information (such as grade of differentiation and lymphovascular invasion); followed by (2) ablation by the use of thermal therapy or cryogens to destroy the metaplastic epithelium, which when accompanied by acid suppression ensures squamous re-epithelialization.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Erratum
    In the article, “Colorectal endoscopic submucosal dissection in the United States: Why do we hear so much about it and do so little of it?” by Rex et al. (Gastrointest Endosc 2017;85:554-8), Dr Hassan’s name was misspelled. It should be Cesare Hassan.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Ankie Reumkens, Ad A.M. Masclee, Christine M. Bakker
    Postcolonoscopy mortality: Bowel preparation to blame?
    Bowel preparation for colonoscopy should be safe, without clinically relevant shifts in serum potassium levels. It has been shown that polyethylene glycol (PEG) solutions may cause hypokalemia, but the prevalence, magnitude, and clinical consequences of hypokalemia associated with low-volume PEG bowel preparation are not known. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal outcome at our secondary care hospital.