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Mise à jour le : 25-07-2017




Les derniers abstracts de la revue Gastrointestinal Endoscopy :


    Date de mise en ligne : Lundi 24 juillet 2017
    Diane Lorenzo, Théophile Guilbaud, Jean Michel Gonzalez, Alban Benezech, Anne Dutour, Sandrine Boullu, Stéphane Berdah, Thierry BÚge, Marc Barthet
    Endoscopic treatment of fistulas after sleeve gastrectomy: a comparison of internal drainage versus closure
    Post-sleeve gastrectomy fistulas (PSGF) are major adverse events of bariatric surgery. The endoscopic management strategy evolved from closure to internal drainage (ID) after 2013. The main objective was to evaluate and compare these different approaches.


    Date de mise en ligne : Lundi 24 juillet 2017
    Yen-I. Chen, Rastislav Kunda, Andrew C. Storm, Hanaa Dakour Aridi, Christopher C. Thompson, Jose Nieto, Ali A. Siddiqui, Theodore James, Shayan Irani, Majidah Bukhari, Olaya Brewer Gutierrez, Amol Agarwal, Lea Fayad, Robert Moran, Nuha Alammar, Omid Sanaei, Marcia I. Canto, Vikesh K. Singh, Todd H. Baron, Mouen A. Khashab
    EUS-guided gastroenterostomy: a multicenter study comparing the direct and balloon-assisted techniques
    Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is a developing modality in the management of gastric outlet obstruction (GOO) with several technical approaches including the direct and balloon-assisted techniques. The aim of this study is to compare the direct with the balloon-assisted modality while further defining the role of EUS-GE in GOO.


    Date de mise en ligne : Lundi 24 juillet 2017
    Anthony Yuen Bun Teoh, Charing Ching Ning Chong, Wing Wa Leung, Simon Kin Cheong Chan, Yee Kit Tse, Enders Kwok Wai Ng, Paul Bo San Lai, Justin Che Yuen Wu, James Yun Wong Lau
    Electroacupuncture-reduced sedative and analgesic requirements for diagnostic EUS: a prospective, randomized, double-blinded, sham-controlled study
    The role of electroacupuncture (EA) in reducing sedative and analgesic requirements during EUS is uncertain. The aim of the current study is to investigate the efficacy of EA in reducing procedure-related pain and discomfort during EUS.


    Date de mise en ligne : Lundi 24 juillet 2017
    Brisas M. Flores, Anthony OÊŒConnor, Alan C. Moss
    Impact of Mucosal Inflammation on Risk of Colorectal Neoplasia in Patients with Ulcerative Colitis: A Systematic Review and Meta-Analysis
    Long-standing ulcerative colitis is an established risk factor for colorectal neoplasia. A number of observational studies have suggested that evidence of mucosal inflammation (endoscopic or histologic) is associated with a greater risk for colorectal neoplasia than is mucosal healing. Our goal was to systematically analyze the risk of colorectal neoplasia in ulcerative colitis patients with ongoing mucosal inflammation to better inform surveillance strategies.


    Date de mise en ligne : Vendredi 21 juillet 2017
    John C. Fang, Gary Faerber, Jewel Samadder
    Digital rectal examination for prostate cancer screening performed with colonoscopy for colon cancer screening: Two for the price of one


    Date de mise en ligne : Jeudi 20 juillet 2017
    Soo Jung Park, Hyojin Park, Yong Chan Lee, Chang Hwan Choi, Tae Joo Jeon, Jun Chul Park, Jie-Hyun Kim, Young Hoon Youn, Yu Jin Kim, Jae Hak Kim, Kwang Jae Lee, Sun Gyo Lim, Hyung Gil Kim, Byoung Wook Bang
    Effect of scheduled second-look endoscopy on peptic ulcer bleeding: a prospective randomized multicenter trial
    This study aimed to investigate the effectiveness of scheduled second-look EGD with endoscopic hemostasis on peptic ulcer rebleeding and sought to identify the risk factors related to the need for second-look EGD.


    Date de mise en ligne : Mercredi 19 juillet 2017
    E. Rajan, B. Al-Bawardy, C.J. Gostout, L.M. Wong Kee Song, J.L. Deters, M.A. Knipschield, C.E. Bernard, G. Farrugia
    Endoscopic Muscle Biopsy (EMB) of the Duodenum and Rectum: A Pilot Survival Study in a Porcine Model to Detect Myenteric Neurons
    Small bowel and colorectal muscle biopsies require a surgical approach. Advancing our understanding of the pathophysiology of motility disorders, such as functional bowel disorders, intestinal pseudo-obstruction and slow transit constipation, is hindered by our inability to non-invasively obtain muscularis propria (MP) for evaluation of multiple cell types, including myenteric neurons. The aims of this study were to determine (1) technical feasibility, reproducibility and safety of performing duodenal endoscopic muscle biopsy (dEMB) and rectal endoscopic muscle biopsy (rEMB) using a clip-assist technique; and (2) presence of myenteric neurons in tissue samples.


    Date de mise en ligne : Mercredi 19 juillet 2017
    Akira Dobashi, Elizabeth Rajan, Mary A. Knipschield, Christopher J. Gostout
    Endoscopic full-thickness resection using suture loop needle-T-tag tissue anchors in the porcine stomach (with video)
    Endoscopic full-thickness resection (EFTR) is still challenging and a reliable technique is desirable. The aim of this study was to evaluate the feasibility of controlled EFTR using a pseudopolyp made from suture loop needle-T-tag (SLNT) tissue anchors in ex vivo porcine stomachs.


    Date de mise en ligne : Mercredi 19 juillet 2017
    Shivkumar Budihal, Krish Ragunath
    Cardiac ischemia after epinephrine injection during EMR for a large rectal polyp


    Date de mise en ligne : Mardi 18 juillet 2017
    Jiaqi Dong, Kunyan Wei, Jiaqi Deng, Xi Zhou, Xiaomei Huang, MingMing Deng, Muhan LĂŒ
    Effects of antithrombotic therapy on bleeding after endoscopic submucosal dissection: A systematic review and meta-analysis
    Bleeding is the most common adverse event after ESD. Although several studies have been reported about the use of antithrombotic agents and post-ESD bleeding, many issues remain controversial. We conducted a meta-analysis and systematic review to evaluate the effects of antithrombotic therapy for post-ESD bleeding.


    Date de mise en ligne : Samedi 15 juillet 2017
    Haruka Toyonaga, Masashi Fukushima, Tetsuro Inokuma, Yukihiro Imai
    Mantle cell lymphoma involving the esophagus evaluated by magnifying endoscopy with narrow-band imaging


    Date de mise en ligne : Samedi 15 juillet 2017
    Bing-Rong Liu, Ji-Tao Song, Zhong-Hong Liu, Ge Lou, Ling-Jian Kong
    Endoscopic transcecal appendectomy: the first human case report


    Date de mise en ligne : Samedi 15 juillet 2017
    Tatsuya Koshitani, Shuji Nakagawa, Yoshito Itoh
    EUS-guided antegrade stent placement for unresectable malignant hilar biliary strictures using a stent-in-stent method


    Date de mise en ligne : Samedi 15 juillet 2017
    Marcia Irene Canto, Julian Abrams, Hannah Kunzli, Bas Weusten, Yoshihiro Komatsu, Blair Jobe, Charles J. Lightdale
    Nitrous oxide cryotherapy for treatment of esophageal squamous cell neoplasia: initial multicenter international experience with a novel portable cryoballoon ablation system (with video)
    Early esophageal squamous cell neoplasia (ESCN) can be successfully treated by endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), or radiofrequency ablation (RFA). A new portable, battery-powered cryotherapy system using nitrous oxide (cryoballoon focal ablation system (CbFAS) has been used for Barrett’s esophagus. It consists of a small hand-held device containing liquid nitrous oxide, which converts to gas within a low-pressure–compliant through-the-scope balloon and freezes targeted mucosa in contact with the balloon.


    Date de mise en ligne : Samedi 15 juillet 2017
    Mohammad Esmadi, Dina Ahmad, Kurt Fisher, Alexander Hewlett
    Atypical appearance of a rectal Dieulafoy's lesion


    Date de mise en ligne : Samedi 15 juillet 2017
    Shoichiro Mine, Eisuke Ozawa, Ken Ohnita, Kuniko Abe, Kazuhiko Nakao
    A case of IgG4-related disease presenting with multiple gastric submucosal tumors


    Date de mise en ligne : Vendredi 14 juillet 2017
    EvĆŸen Machytka, Marek BuĆŸga, Pavel Zonca, David B. Lautz, Marvin Ryou, Donald C. Simonson, Christopher C. Thompson
    Partial jejunal diversion using an incisionless magnetic anastomosis system: 1-year interim results in subjects with obesity and diabetes
    The majority of patients with type 2 diabetes mellitus (T2DM) have obesity. Studies show that bariatric surgery is superior to medical treatment for remission of T2DM. Nevertheless, very few patients undergo surgery, and a less-invasive endoscopic alternative is desirable.


    Date de mise en ligne : Vendredi 14 juillet 2017
    Seiichiro Abe, Prasad G. Iyer, Ichiro Oda, Nobuo Kanai, Yutaka Saito
    Approaches for stricture prevention after esophageal endoscopic resection
    Endoscopic resection of extensive esophageal lesions has become more common as endoscopic resection techniques and equipment has developed. However, extensive esophageal endoscopic resections can cause postoperative esophageal strictures, which have a negative impact on the quality of life of patients. We aimed to review current treatments and innovative approaches to prevent esophageal strictures after widespread endoscopic resection of esophageal lesions.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Hai Yun Shi, Francis KL. Chan, Akira Higashimori, Moe Kyaw, Jessica YL. Ching, Heyson CH. Chan, Joey CH. Chan, Anthony WH. Chan, Kelvin LY. Lam, Raymond SY. Tang, Justin CY. Wu, Joseph JY. Sung, Siew C. Ng
    A prospective study on second-generation colon capsule endoscopy to detect mucosal lesions and disease activity in ulcerative colitis (with video)
    Mucosal healing is the goal for ulcerative colitis (UC) therapy, but needs to be confirmed under colonoscopy. Colon capsule endoscopy (CCE) is a noninvasive technique for colon investigation. Our study investigated the accuracy of the second-generation CCE (CCE-2) to assess mucosal lesions and disease activity in UC.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Hyo-Joon Yang, Sang Gyun Kim, Joo Hyun Lim, Ji Min Choi, Sooyeon Oh, Jae Yong Park, Seung Jun Han, Jung Kim, Hyunsoo Chung, Hyun Chae Jung
    Novel risk stratification for metachronous recurrence after curative endoscopic submucosal dissection for early gastric cancer
    This study stratified the risk of developing metachronous gastric cancer (MGC) after curative endoscopic submucosal dissection (ESD) of early gastric cancer (EGC) to enable the customization of endoscopic surveillance for MGC.


    Date de mise en ligne : Jeudi 13 juillet 2017
    David J. Tate, Mahesh Jayanna, Halim Awadie, Lobke Desomer, Ralph Lee, Stephen J. Heitman, Mayenaaz Sidhu, Kathleen Goodrick, Nicholas G. Burgess, Hema Mehajan, Duncan McLeod, Michael J. Bourke
    A standardized imaging protocol for the endoscopic prediction of dysplasia within sessile serrated polyps (with video)
    Dysplasia within sessile serrated polyps (SSPs) is difficult to detect, may be mistaken for an adenoma risking incomplete resection of the background serrated tissue, and is strongly implicated in interval cancer after colonoscopy. The use of endoscopic imaging to detect dysplasia within SSP has not been systematically studied.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Julian A. Abrams, Sri Komanduri, Nicholas J. Shaheen, Zengri Wang, Richard I. Rothstein
    Radiofrequency ablation for the treatment of weight regain after Roux-en-Y gastric bypass surgery
    Roux-en-Y gastric bypass (RYGB) surgery is an established modality for the treatment of morbid obesity. However, approximately one-quarter of patients experience weight regain after initially successful weight loss. Endoscopic therapy targeting the gastric remnant pouch represents a novel potential strategy to re-induce weight loss in this population. We performed a pilot trial of radiofrequency ablation (RFA) of the gastric remnant pouch after RYGB to determine feasibility, safety and efficacy for weight loss.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Gabriel D. Lang, Cassandra Fritz, Trisha Bhat, Koushik K. Das, Faris M. Murad, Dayna S. Early, Steven A. Edmundowicz, Vladimir M. Kushnir, Daniel K. Mullady
    EUS-guided drainage of peripancreatic fluid collections with lumen-apposing metal stents and plastic double-pigtail stents: comparison of efficacy and adverse event rates
    Transmural drainage with double-pigtail plastic stents (DPPSs) was the mainstay of endoscopic therapy for symptomatic peri-pancreatic fluid collections (PPFCs) until the introduction of lumen-apposing covered self-expanding metal stents (LAMSs). Currently, there is limited data regarding the efficacy and adverse event rate of LAMS compared with DPPS.


    Date de mise en ligne : Jeudi 13 juillet 2017
    L.(Laurien) J. van Nimwegen, L. (Leon) M.G. Moons, J. (Joost) M.J. Geesing, L. (Rene) Arensman, M.M. (Miangela) Laclé, I. (Ivo) A.M.J. Broeders, P. (Peter)P. Viergever, J. (John) N. Groen, K. (Koen) Kessels, M. (Thijs) P. Schwartz
    The Extent of Unnecessary Surgery for Benign Rectal Polyps in the Netherlands
    Minimally invasive techniques are available to safely and efficaciously remove even the largest rectal polyps. This study aimed to investigate the magnitude of cases still referred for radical rectal surgery, the reasons for theses referrals, and to perform a re-evaluation of cases potentially suitable for endoscopic therapy.


    Date de mise en ligne : Jeudi 13 juillet 2017
    Rajat Garg, Heidi D. Lehrke, Barham K. AbuDayyeh, Tarun Rustagi
    Incidental Giardiasis Diagnosed during Transduodenal EUS-FNA


    Date de mise en ligne : Vendredi 07 juillet 2017
    Yoshihiro Furuichi, Takuji Gotoda, Yoshitaka Kasai, Hirohito Takeuchi, Yuu Yoshimasu, Takashi Kawai, Takao Itoi
    Role of dual red imaging to guide intravariceal sclerotherapy injection of esophageal varices (with videos)
    Dual red imaging (DRI) is a novel image-enhanced endoscopy technique that can increase the visibility and predict the depth of esophageal varices (EVs). The recurrence rate of EVs after endoscopic injection sclerotherapy (EIS) reportedly decreases by intravariceal injection of a sclerosant. We evaluated prospectively whether the EIS success rate was increased by DRI compared with the white light (WLI) mode.


    Date de mise en ligne : Mercredi 05 juillet 2017
    Emma Z. Mi, Ella Z. Mi, Massimiliano di Pietro, Maria O’Donovan, Richard H. Hardwick, Susan Richardson, Hisham Ziauddeen, Paul C. Fletcher, Carlos Caldas, Marc Tischkowitz, Krish Ragunath, Rebecca C. Fitzgerald
    A comparative study of endoscopic surveillance in hereditary diffuse gastric cancer according to CDH1 mutation status
    Hereditary diffuse gastric cancer (HDGC) accounts for 1% of gastric cancer cases. For patients with a germline CDH1 mutation, risk-reducing gastrectomy is recommended. However, for those delaying surgery or families with no causative mutation identified, regular endoscopy is advised. This study aimed to determine the yield of signet ring cell carcinoma (SRCC) foci in individuals with a CDH1 pathogenic variant compared with those without and how this varies with successive endoscopies.


    Date de mise en ligne : Mardi 04 juillet 2017
    Roberto Di Mitri, Filippo Mocciaro, Maurizio Lipani
    One-session “two-step” technique for endoscopic full-thickness resection of a large rectal adenocarcinoma: when it is possible, overcome the lesion’s size


    Date de mise en ligne : Mardi 04 juillet 2017
    Michael J. Bartel, Amitabh Srivastava, Stuart Gordon, Richard I. Rothstein, Heiko Pohl
    Subsquamous intestinal metaplasia is common in treatment-naïve Barrett’s esophagus
    Barrett’s intestinal metaplasia may extent beneath normal squamous epithelium at the squamocolumnar junction (SCJ) and therefore escape surveillance biopsies. The prevalence of subsquamous intestinal metaplasia (SSIM) in patients undergoing Barrett's esophagus (BE) surveillance is unknown. Our aim was to examine the prevalence and distribution of SSIM proximal to the SCJ in patients undergoing BE surveillance.


    Date de mise en ligne : Vendredi 30 juin 2017
    Silvia Carrara, Milena Di Leo, Paola Spaggiari, Pietro Francesco Bagnoli, Alessandro Repici
    A rectal metastases from malignant mucinous cystic neoplasm of the pancreas mimicking a rectal carcinoma


    Date de mise en ligne : Vendredi 30 juin 2017
    Sabrina Sy, Hassan Siddiki, Jennifer Horsley-Silva, Thomas Byrne, Dora Lam-Himlin
    Sevelamer Resin Bezoar Presenting as a Cecal Mass


    Date de mise en ligne : Vendredi 30 juin 2017
    Ken Kamata, Mamoru Takenaka, Kosuke Minaga, Masatoshi Kudo
    Utility of contrast-enhanced harmonic EUS for evaluating the effects of steroid therapy in a case of IgG4-negative focal autoimmune pancreatitis


    Date de mise en ligne : Samedi 24 juin 2017
    Ramkaji Baniya, Sunil Upadhya, Subash Chandra Subedi, Jahangir Khan, Prabin Sharma, Tabrez Shaik Mohammed, Ghassan Bachuwa, Laith H. Jamil
    Balloon enteroscopy versus spiral enteroscopy for small-bowel disorders: a systematic review and meta-analysis
    Two novel enteroscopic procedures, balloon enteroscopy (BE) and spiral enteroscopy (SE), have revolutionized the diagnostic and therapeutic approach to small-bowel disorders. These disorders that historically required surgical interventions are now investigated and managed nonsurgically. There are only a few weakly powered studies comparing the outcomes of SE and BE. We conducted a systematic review and meta-analysis to compare the efficacy and safety of these 2 procedures.


    Date de mise en ligne : Jeudi 22 juin 2017
    Wai K. Leung, Hsiu J. Ho, Jaw-Town Lin, Ming-Shiang Wu, Chun-Ying Wu
    Prior gastroscopy and mortality in patients with gastric cancer: a matched retrospective cohort study
    The role of prior gastroscopy on outcome of gastric cancer patients remains unknown. This study determines the association between intervals of prior gastroscopy and mortality in patients with gastric cancer.


    Date de mise en ligne : Jeudi 22 juin 2017
    Matthew A. Kluge, J. Luke Williams, Connie K. Wu, Brian C. Jacobson, Paul C. Schroy, David A. Lieberman, Audrey H. Calderwood
    Inadequate Boston Bowel Preparation Scale Scores Predict the Risk of Missed Neoplasia on Next Colonoscopy
    The risks of missed findings after inadequate bowel preparation are not fully characterized in a diverse cohort. We aimed to evaluate the likelihood of missed polyps after an inadequate preparation as assessed using the Boston Bowel Preparation Scale (BBPS).


    Date de mise en ligne : Jeudi 22 juin 2017
    Zhouwen Tang, Daniel S. Zhang, Aaron P. Thrift, Kalpesh K. Patel
    Impact of cap-assisted colonoscopy on learning curve and quality in colonoscopy: a randomized controlled trial
    Colonoscopy competency assessment in trainees have traditionally been informal. Comprehensive metrics such as the Assessment of Competency in Endoscopy (ACE) tool suggest competency thresholds are higher than assumed. cap-assisted colonoscopy (CAC) may improve competency but data in novice trainees are lacking. We compare CAC versus standard colonoscopy (SC) among novice trainees in a randomized controlled trial.


    Date de mise en ligne : Mercredi 21 juin 2017
    Qisheng Zhang, Peng Gao, Bin Han, Jianhua Xu, Yucui Shen
    Polypectomy for complete endoscopic resection of small colorectal polyps
    Small colorectal polyps are encountered frequently and may be incompletely removed during colonoscopy. The optimal technique for removal of small colorectal polyps is uncertain. The aim of this study was to compare the incomplete resection rate (IRR) by using EMR or cold snare polypectomy (CSP) for the removal of small adenomatous polyps.


    Date de mise en ligne : Mardi 20 juin 2017
    Mohammad Yaghoobi, Yaser Meeralam, Khalil Al-Shammari
    Diagnostic accuracy of EUS compared with MRCP in detecting choledocholithiasis: a meta-analysis of diagnostic test accuracy of head-to-head studies
    There is a wide range of reported sensitivity and specificity for endoscopic ultrasound (EUS) and magnetic resonance cholangiopancreatography (MRCP) in the diagnosis of the choledocholithiasis with lack of a proper meta-analysis of diagnostic test accuracy (DTA) using head-to-head comparison. Here, we aimed at comparing the diagnostic accuracy of EUS and MRCP in detecting choledocholithiasis using appropriate methodology recommended by the Cochrane Collaboration.


    Date de mise en ligne : Mercredi 14 juin 2017
    Hyun Gun Kim, Young-Seok Cho, Jae Myung Cha, Jeong Eun Shin, Kyeong Ok Kim, Hyo-Joon Yang, Hoon Sup Koo, Young-Eun Joo, Sun-Jin Boo
    Risk of metachronous neoplasia on surveillance colonoscopy in young patients with colorectal neoplasia
    Few prior reports exist that address the appropriate colonoscopy surveillance interval for individuals <50 years old. We compared the risk of metachronous neoplasia between younger (20-49 years) and older (50-54 years) cohorts.


    Date de mise en ligne : Mercredi 14 juin 2017
    Ken Kamata, Mamoru Takenaka, Shunsuke Omoto, Takeshi Miyata, Kosuke Minaga, Kentaro Yamao, Hajime Imai, Toshiharu Sakurai, Naoshi Nishida, Takaaki Chikugo, Yasutaka Chiba, Ippei Matsumoto, Yoshifumi Takeyama, Masatoshi Kudo
    Impact of avascular areas, as measured by contrast-enhanced harmonic EUS, on the accuracy of fine-needle aspiration for pancreatic adenocarcinoma
    Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is used for the diagnosis of pancreatic adenocarcinoma, but sometimes the method results in a false negative. Occasionally, an avascular area may be observed within the pancreatic adenocarcinoma tumor during contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS). The aim of this study was to evaluate whether the diagnostic sensitivity of EUS-FNA for pancreatic adenocarcinoma was affected by the presence of avascularity on CH-EUS.


    Date de mise en ligne : Mardi 13 juin 2017
    Kazuki Boda, Shiro Oka, Shinji Tanaka, Shinji Nagata, Masaki Kunihiro, Toshio Kuwai, Yuko Hiraga, Akira Furudoi, Motomi Terasaki, Koichi Nakadoi, Makoto Higashiyama, Hideharu Okanobu, Morihisa Akagi, Kazuaki Chayama
    Clinical outcomes of endoscopic submucosal dissection for colorectal tumors: a large multicenter retrospective study from the Hiroshima GI Endoscopy Research Group
    Although advanced high-volume centers have reported good outcomes of colorectal endoscopic submucosal dissection (ESD), a limited number of highly skilled experts in specialized institutions performed these procedures. We undertook a retrospective multicenter survey, which included nonspecialized hospitals, to investigate the clinical outcomes of colorectal ESD.


    Date de mise en ligne : Samedi 10 juin 2017
    Chan Hyuk Park, Se Woo Park, Bomi Hyun, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi
    Efficacy and safety of etomidate-based sedation compared with propofol-based sedation during ERCP in low-risk patients: a double-blind, randomized, noninferiority trial
    Etomidate is a short-acting intravenous hypnotic with a safety profile that is superior to alternative drugs such as propofol. However, there is a lack of evidence on the safety of etomidate in ERCP. The objective of this study was to compare efficacy and safety profiles of etomidate and propofol for endoscopic sedation.


    Date de mise en ligne : Jeudi 08 juin 2017
    Stephen M. Vindigni, Hejin Hahn, Qing Zhang
    Intermittent obstructive symptoms in a patient with diphyllobothriasis
    A 68-year-old man with hypertension, sleep apnea, and GERD presented to an outpatient gastroenterology clinic with worsening constipation, bloating, mild diffuse abdominal pain, and nausea. He described passing formed, nonbloody stools with mucus, for which he had been using saline solution enemas, with minimal relief. He described a feeling of incomplete evacuation with associated abdominal pressure and had modified his diet to mostly liquids, with an improvement in symptoms. The results of his examination were normal overall, with bowel sounds present and a nontender abdomen.


    Date de mise en ligne : Mardi 06 juin 2017
    Iyad Khamaysi, Alain Suissa
    Hemobilia
    A 69-year-old woman was admitted with right upper quadrant abdominal pain, melena, and jaundice (Quincke's triad). Her medical history was remarkable for hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease), with multiple prior episodes of epistaxis and the need for packed red blood cell transfusions. On physical examination, she appeared to be jaundiced and had right upper quadrant tenderness to palpation. Laboratory tests revealed elevated liver transaminases and direct hyperbilirubinemia.


    Date de mise en ligne : Mardi 06 juin 2017
    Eric M. Nelsen, Daniel E. Abbott, Patrick R. Pfau, Mark E. Benson
    EUS core biopsy leading to duodenal brunneroma diagnosis
    A 56-year-old man presented with vague symptoms of fullness and early satiety. Ultimately, upper endoscopy revealed a large duodenal polyp at least 4 cm long with occasional retrograde protrusion through the pylorus into the stomach (A). Biopsy specimens from upper endoscopy demonstrated duodenal mucosa with gastric foveolar metaplasia. The patient underwent EUS to better characterize the lesion, which confirmed a 3.9-cm lesion that appeared to originate from within the deep mucosa, with no involvement of the muscularis propria (B).


    Date de mise en ligne : Lundi 05 juin 2017
    Roberto Di Mitri, Filippo Mocciaro, Antonio Maiorana, Walter Alio, Ambrogio Orlando
    Endoscopic rescue treatment in a pregnant ulcerative colitis patient with a severe colonic stricture: a conservative approach to bring the pregnancy to term
    A 28-year-old woman with ulcerative colitis, 29 weeks into her first pregnancy, was admitted because of constipation, vomiting, and severe bloating. An abdominal radiograph and MRI revealed a transverse colon of 12.8 cm (A) secondary to a sigmoid stricture (B). The abdominal radiograph (A, left) and MRI (A, right) showed the dilated colon (yellow arrow) resulting from colonic stricture (red arrow) and the fetus (green arrow).


    Date de mise en ligne : Samedi 03 juin 2017
    Noelia Alcaide, Sara Lorenzo Pelayo, Carmen Alonso Martin, Ana Macho Conesa, Francisco Blanco-Antona
    Colovesical fistula: visualization of the bladder during colonoscopy
    An 82-year-old man with hypogastric pain, fecaluria, and pneumaturia was admitted to the hospital. The patient had undergone surgery for rectal carcinoma with adjuvant radiotherapy 15 years earlier and 2 transurethral resections for bladder carcinoma 7 years earlier. Subsequently, the patient experienced several adverse events, including intestinal obstruction that required surgery, anastomotic stenosis treated with endoscopic dilations, radiation colitis, intravesical lithiasis, and ureteral stenosis managed with percutaneous nephrostomy.


    Date de mise en ligne : Samedi 03 juin 2017
    Xiaoyan Ning, Biao Liang, Qinyi Liu, Xiaowu Chen, Ming Xu
    Gastric inflammatory myofibroblastic tumor identified as ectopic pancreas and treated by endoscopic submucosal dissection


    Date de mise en ligne : Vendredi 02 juin 2017
    Jessica R. Allegretti, Zain Kassam, Majdi Osman, Shrish Budree, Monika Fischer, Colleen R. Kelly
    The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection
    Clostridium difficile infection is the most common health care–associated infection in the United States. Recently, fecal microbiota transplantation (FMT) has emerged as an effective and safe therapy for recurrent C difficile infection; however, despite rapid adoption there is no standardized clinical approach. Given the rapid adoption of FMT, in part because of stool banks, there is a need for a practical primer for clinicians to safely perform FMT. Accordingly, we aim to provide a simple approach entitled the 5D FMT framework to guide physicians.


    Date de mise en ligne : Vendredi 02 juin 2017
    Hiroyuki Hatamori, Masaya Wada, Youhei Taniguchi, Tetsuro Inokuma
    Pancreatic pseudocyst localized in the gastric wall after EUS-guided FNA of type 1 autoimmune pancreatitis
    A 67-year-old man with diffuse enlargement of the pancreas suspected to have type 1 autoimmune pancreatitis (AIP) underwent EUS-guided FNA to confirm the pathologic diagnosis (A). FNA was performed through a transgastric approach, and 5 passes were made with a 21G needle with attention to avoid puncture of the main pancreatic duct. The pathologic result was consistent with AIP. Five days later, the patient was admitted to our hospital with abdominal pain and vomiting. A CT scan showed a newly developed 7 × 6 cm cystic mass in the gastric wall with no fluid collection in the retroperitoneal space (B, C).


    Date de mise en ligne : Jeudi 01 juin 2017
    Wouter F.W. Kappelle, Daisy Walter, Paul H. Stadhouders, Hendrik J.A. Jebbink, Frank P. Vleggaar, Peter J. van der Schaar, Jan Willem Kappelle, Ingeborg van der Tweel, Medard F.M. Van den Broek, Frank J. Wessels, Peter D. Siersema, Jan F. Monkelbaan
    Electromagnetic-guided placement of nasoduodenal feeding tubes versus endoscopic placement: a randomized, multicenter trial
    Electromagnetic-guided placement (EMP) of a nasoduodenal feeding tube by trained nurses is an attractive alternative to EGD-guided placement (EGDP). We aimed to compare EMP and EGDP in outpatients, ward patients, and critically ill patients with normal upper GI anatomy.


    Date de mise en ligne : Jeudi 01 juin 2017
    Bram Verstockt, Annelien Van Driessche, Marc De Man, Pieter van der Spek, Koen Hendrickx, Veerle Casneuf, Pieter Dobbels, Yves Van Molhem, Jo Vandervoort
    Ten-year survival after endoscopic stent placement as a bridge to surgery in obstructing colon cancer
    Self-expandable metal stents are used increasingly in the treatment of obstructing colorectal cancer (CRC). Although endoscopic colon stenting is widely accepted in palliation, disagreement exists about its role in a curative setting. This study aims to describe long-term survival data in a large patient group treated with colon stenting as a bridge to surgery for CRC.


    Date de mise en ligne : Mardi 30 mai 2017
    Yutaka Mitsunaga, Toshihiro Nishizawa, Ai Fujimoto, Aya Sasaki, Naohisa Yahagi
    Successful endoscopic submucosal dissection for superficial esophageal cancer on solitary esophageal varix
    Solitary esophageal varix is found in approximately 1% of all patients undergoing upper digestive endoscopy. Here we report a unique case of superficial esophageal cancer on a solitary esophageal varix successfully resected by endoscopic submucosal dissection (ESD). An 80-year-old man underwent upper GI endoscopy at his annual checkup. A slight reddish area was found on an esophageal solitary varix (A), and it was diagnosed as esophageal cancer by narrow-band imaging (NBI) magnification, which showed a brownish area (B) and a dilated irregular intrapapillary capillary loop (C).


    Date de mise en ligne : Mardi 30 mai 2017
    Kyosuke Tanaka, Yasuhiko Hamada, Misaki Nakamura, Reiko Yamada, Yoshiyuki Takei
    Hymenolepis nana infection detected by magnifying colonoscopy with narrow-band imaging (with video)
    A 29-year-old man with Crohn’s disease underwent colonoscopy because of postprandial abdominal pain without diarrhea. Remission of Crohn’s ileocolitis had been achieved by the administration of infliximab every 8 weeks. Colonoscopy revealed a thin white object (A), which looked like a small strand of white mucus. Magnifying endoscopy revealed slow movement (B), and narrow-band imaging (NBI) produced a clearer image (C; Video 1, available online at www.giejournal.org). Endoscopic removal of the tapeworm by biopsy forceps was performed.


    Date de mise en ligne : Mardi 30 mai 2017
    Nitin Vashistha, Suneel Chakravarty, Dinesh Singhal
    Cronkhite-Canada syndrome
    A 36-year-old man was seen with generalized weakness, watery diarrhea, and loss of weight (>15 kg) for 4 months. On examination he had a thin build and his vital signs were stable. He had a dry, swollen tongue with loss of papillae (A). His nail beds were soft and spongy, and the distal parts were discolored. Furthermore, there were hyperpigmented patches over his palms (B). EGD revealed a normal esophagus with marked hypertrophy of the gastric folds (C). A colonoscopy showed multiple sessile polyps throughout the colon and rectum (D).


    Date de mise en ligne : Mardi 30 mai 2017
    Yuji Maehata, Yoshifumi Hori, Minako Hirahashi, Hidetaka Yamamoto, Motohiro Esaki
    Diffuse gastric metastases from salivary duct carcinoma
    A 64-year-old man underwent a right parotidectomy for a parotid gland tumor. Histologic examination revealed poorly differentiated adenocarcinoma with lymph node metastases, and the tumor was diagnosed as salivary duct carcinoma (SDC). Adjuvant chemotherapy was performed for 8 months until CT revealed no residual lesions of SDC. Thirteen months after the surgery, he underwent surveillance EGD and was referred to our hospital for scrutiny of the gastric lesions. Under EGD, thickened gastric folds in the greater curvature of the gastric corpus were discontinuously and ambiguously identified (A), and the surface of these lesions was reddish and coarse (B).


    Date de mise en ligne : Samedi 27 mai 2017
    Yoshinobu Okabe, Tomoyuki Ushijima, Masafumi Yasunaga, Yutarou Mihara, Takuji Torimura
    A rare case of sarcoidosis in accessory spleen
    A 73-year-old woman with sarcoidosis of the heart, lungs, and eyes had been receiving steroid therapy for 12 years (maintenance dose at prednisolone 5 mg/day) and had undergone pacemaker implantation 4 years earlier for complete atrioventricular block. Fluorodeoxyglucose (FDG) positron emission tomography for scrutiny of cardiac sarcoidosis incidentally revealed abnormal accumulation (FDG maximum standardized uptake value, 4.8) in the pancreatic tail (A), and she was referred to our department on suspicion of pancreatic cancer.


    Date de mise en ligne : Vendredi 26 mai 2017
    Andrea Parodi, Geoffroy Vanbiervliet, Cesare Hassan, Xavier Hebuterne, Antonella De Ceglie, Rosa Angela Filiberti, Cristano Spada, Massimo Conio
    Colon capsule endoscopy to screen for colorectal neoplasia in those with family histories of colorectal cancer
    Colon capsule endoscopy (CCE) has been recognized as an alternative for colorectal cancer (CRC) screening in average-risk people. Our aim was to prospectively assess the accuracy of CCE as a screening tool in first-degree relatives (FDRs) of people with CRC by using optical colonoscopy (OC) with segmental unblinding as the reference standard.


    Date de mise en ligne : Vendredi 26 mai 2017
    Aymeric Becq, Gabriel Rahmi, Guillaume Perrod, Christophe Cellier
    Hemorrhagic angiodysplasia of the digestive tract: pathogenesis, diagnosis, and management
    GI angiodysplasia (GIA) is an acquired vascular superficial lesion, which presents typically as a bright red, irregular, round, slightly elevated lesion. GIAs are often seen in patients aged >60 years and are mostly located in the colon (cecum and ascending colon). The cause and mechanisms of GIA have yet to be completely understood. Small-bowel GIAs often are diagnosed in the setting of obscure GI bleeding. In some cases, GIAs are associated with aortic stenosis, von Willebrand’s disease, chronic renal disease, and liver disease.


    Date de mise en ligne : Vendredi 26 mai 2017
    Daniela Guerrero Vinsard, Mark E. Stark, Jason T. Lewis, Ming-Hsi Wang
    Nonsteroidal anti-inflammatory drug–induced protein-losing enteropathy: a great masquerade of Crohn’s disease
    A 29-year-old woman was referred to our facility because of a 2-year history of relapsing abdominal pain associated with melena, diarrhea, chronic arthralgia, and new onset of lower extremity edema. Previous workup in an outside center included negative results for HLA B-27 testing without radiologic features of spondyloarthropathy. Capsule endoscopy revealed erosions, circular ulcers, and concentric stenosis in the proximal jejunum and ileum (A, B). An abdominal CT scan revealed nonobstructing dilatated and stenotic segments within the ileum (C).


    Date de mise en ligne : Mercredi 24 mai 2017
    Michelle J. Alfa, Maira M. Ribeiro, Cristiana da Costa Luciano, Rodrigo Franca, Nancy Olson, Pat DeGagne, Harminder Singh
    A novel polytetrafluoroethylene-channel model, which simulates low levels of culturable bacteria in buildup biofilm after repeated endoscope reprocessing
    Clinical studies have shown variable culture results from flexible endoscope channels possibly because of low levels of bacteria that are difficult to extract. The aim of this study was to develop a simulated-use buildup biofilm (BBF) model that mimics low levels of viable bacteria after repeated rounds of aldehyde fixation and accumulation.


    Date de mise en ligne : Mercredi 24 mai 2017
    Jose Nieto, Huda Khaleel, Youssef Challita, Melissa Jimenez, Todd H. Baron, Laura Walters, Kelli Hathaway, Ketul Patel, Ali Lankarani, Michael Herman, David Holloman, Sammy Saab
    EUS-guided fine-needle core liver biopsy sampling using a novel 19-gauge needle with modified 1-pass, 1 actuation wet suction technique
    EUS-guided fine-needle core biopsy sampling is a safe and effective technique for diagnosis of focal liver lesions. However, data are limited in its role in parenchymal disease. We evaluated the utility of EUS-guided parenchymal liver biopsy sampling with a modified 1-pass wet suction technique (EUS-modified liver biopsy sampling [EUS-MLB]) in patients with unexplained increase in liver-associated tests.


    Date de mise en ligne : Mardi 23 mai 2017
    Sajan Jiv Singh Nagpal, Dhruvika Mukhija, Madhusudhan Sanaka, Rocio Lopez, Carol A. Burke
    Metachronous colon polyps in younger versus older adults: a case-control study
    The incidence of colorectal cancer in the United States has decreased substantially in individuals aged 50 and older. In contrast, it is increasing in young adults. The polyp characteristics on baseline and follow-up colonoscopy in young adults are not well characterized. We describe the polyp characteristics on baseline and follow-up colonoscopy in adults <40 years and determined factors associated with the occurrence of metachronous, advanced neoplasia or high-risk (HR) polyp features. We compared the occurrence of metachronous advanced neoplasia in young adults with those 50 years and older to assess whether postpolypectomy surveillance guidelines seem appropriate for polyp-bearing adults less than age 40 years.


    Date de mise en ligne : Mercredi 17 mai 2017
    Marco Bassi, Carmelo Luigiano, Stefania Ghersi, Carlo Fabbri, Giulia Gibiino, Lucio Balzani, Giuseppe Iabichino, Alberto Tringali, Raffaele Manta, Massimiliano Mutignani, Vincenzo Cennamo
    A multicenter randomized trial comparing the use of touch versus no-touch guidewire technique for deep biliary cannulation: the TNT study
    There are 2 techniques described for selective bile duct guidewire cannulation, the touch (T) technique (engaging the papilla with a sphincterotome and then advancing the guidewire) and the no-touch (NT) technique (engaging the papilla only with the guidewire). The aim of this prospective, multicenter randomized study was to compare the outcomes of the 2 guidewire cannulation techniques.


    Date de mise en ligne : Mercredi 10 mai 2017
    Yoshihito Tanaka, Hiro-o Yamano, Eiichiro Yamamoto, Hiro-o Matushita, Hironori Aoki, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Michiko Nakaoka, Yuko Yoshida, Makoto Eizuka, Tamotsu Sugai, Hiromu Suzuki, Hiroshi Nakase
    Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia
    Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with BRAF mutation and the CpG island methylator phenotype (CIMP), develop cytologic dysplasia (CD) during the progression of colorectal tumorigenesis. In the present study we aimed to clarify the endoscopic and molecular signatures of SSA/Ps, with and without CD.


    Date de mise en ligne : Mercredi 10 mai 2017
    Navin L. Kumar, Guillaume Kugener, Molly L. Perencevich, John R. Saltzman
    The SAFE-T assessment tool: derivation and validation of a web-based application for point-of-care evaluation of gastroenterology fellow performance in colonoscopy
    Attending assessment is a critical part of endoscopic education for gastroenterology fellows. The aim of this study was to develop and validate a concise assessment tool to evaluate real-time fellow performance in colonoscopy administered via a web-based application.


    Date de mise en ligne : Mercredi 10 mai 2017
    Eisuke Ueshima, Mark Schattner, Robin Mendelsohn, Hans Gerdes, Sebastien Monette, Haruyuki Takaki, Jeremy C. Durack, Stephen B. Solomon, Govindarajan Srimathveeravalli
    Transmural ablation of the normal porcine common bile duct with catheter-directed irreversible electroporation is feasible and does not affect duct patency
    The aim of this study was to evaluate the feasibility and early safety of catheter-directed irreversible electroporation (IRE) of the normal common bile duct (CBD) in swine.


    Date de mise en ligne : Mardi 09 mai 2017
    Gene K. Ma, David A. Pegues, Michael L. Kochman, Kevin Alby, Neil O. Fishman, Marianne Saunders, Carolyn Grous, Daniel T. Dempsey, Gregory G. Ginsberg
    Implementation of a systematic culturing program to monitor the efficacy of endoscope reprocessing: outcomes and costs
    In 2015, the U.S. Food and Drug Administration and Centers for Disease Control and Prevention (CDC) issued guidance for duodenoscope culturing and reprocessing in response to outbreaks of carbapenem-resistant Enterobacteriaceae (CRE) duodenoscope-related infections. Based on this guidance, we implemented best practices for reprocessing and developed a systematic process for culturing endoscopes with elevator levers. The aim of this study is to report the outcomes and direct costs of this program.


    Date de mise en ligne : Jeudi 04 mai 2017
    Andreas Oberbach, Nadine Schlichting, Marco Heinrich, Yvonne Kullnick, Ulf Retschlag, Stefanie Lehmann, Mouen A. Khashab, Anthony N. Kalloo, Vivek Kumbhari
    Gastric mucosal devitalization reduces adiposity and improves lipid and glucose metabolism in obese rats
    The gastric mucosa is an endocrine organ that regulates satiation pathways by expression of orexigenic and anorexigenic hormones. Vertical sleeve gastrectomy (VSG) excludes gastric mucosa and reduces gastric volume. Our study aimed to investigate the independent effects of altering gastric mucosa on obesity and its related comorbidities.


    Date de mise en ligne : Jeudi 04 mai 2017
    Tae Hoon Lee, Tae Hyeon Kim, Jong Ho Moon, Sang Hyub Lee, Hyun Jong Choi, Young Hwangbo, Jong Jin Hyun, Jun-Ho Choi, Seok Jeong, Jong Hyeok Kim, Do Hyun Park, Joung-Ho Han, Sang-Heum Park
    Bilateral versus unilateral placement of metal stents for inoperable high-grade malignant hilar biliary strictures: a multicenter, prospective, randomized study (with video)
    The efficacy of palliative biliary drainage by using bilateral or unilateral self-expandable metal stents (SEMSs) for a malignant hilar biliary stricture (MHS) remains controversial. This prospective, randomized, multicenter study investigated whether bilateral drainage by using SEMSs is superior to unilateral drainage in patients with inoperable MHSs.


    Date de mise en ligne : Mercredi 03 mai 2017
    Froukje B. van Hoeij, Fraukje A. Ponds, Yuki Werner, Joel M. Sternbach, Paul Fockens, Barbara A. Bastiaansen, André J.P.M. Smout, John E. Pandolfino, Thomas Rösch, Albert J. Bredenoord
    Management of recurrent symptoms after per-oral endoscopic myotomy in achalasia
    Per-oral endoscopic myotomy (POEM) has been rapidly gaining ground as a treatment for achalasia. Although POEM is a safe and effective treatment, a subset of patients has persistent or recurrent symptoms after POEM. This study aimed to examine the efficacy of different retreatments after failed POEM.


    Date de mise en ligne : Mercredi 03 mai 2017
    Douglas K. Rex, Prasanna L. Ponugoti, Cynthia S. Johnson, Lisa Kittner, Randy J. Yanda
    Neoplasia at 10-year follow-up screening colonoscopy in a private U.S. practice: comparison of yield to first-time examinations
    Prior studies assessing the yield of a second screening colonoscopy performed 10 years after an initial screening colonoscopy with negative results did not include a control group of persons undergoing a first screening colonoscopy during the same time interval. Our aim was to describe the incidence of neoplasia at a second screening colonoscopy (performed at least 8 years after the first colonoscopy) in average-risk individuals and compare it with the yield of first screening examinations performed during the same time interval.


    Date de mise en ligne : Mercredi 03 mai 2017
    Yun Duk Jung, Woo Chul Chung, Yeon-Ji Kim, Kyong-Hwa Jun, Hyung-Min Chin
    Gastric neuroendocrine tumor mimicking early gastric cancer
    A 55-year-old man visited the gastroenterology department because of an abnormal endoscopic finding on health screening. The patient had no relevant medical history. On endoscopy, a 1.0-cm ovoid, depressed mucosal lesion was observed in the greater curvature side of the lower body (A). It had cutting edges and looked like an early gastric cancer type IIc (B). At pathologic report, a neuroendocrine tumor (NET, G1) was diagnosed (C), and a positive reaction of chromogranin was found. Mitosis was less than 1/10 high-power field, and the Ki-67 index was 1%.


    Date de mise en ligne : Mercredi 03 mai 2017
    Masanori Kobayashi, Ou Yamaguchi, Koji Nagata, Kouichi Nonaka, Shomei Ryozawa
    Acute hemorrhagic gastritis after nivolumab treatment
    A 77-year-old man was admitted with a history of epigastralgia that had lasted for several months and hematemesis. Before admission, nivolumab (3 mg/kg) had been started for epidermal growth factor receptor—mutant metastatic lung cancer in 10 courses over 4 months. After admission, upper endoscopy revealed hemorrhagic gastritis evenly spreading over the entire gastric mucosa with a white coating (A-D). Histologically, there was marked lymphoplasmacytic and neutrophilic infiltration in the fundic gland mucosa.


    Date de mise en ligne : Mercredi 03 mai 2017
    Barham K. Abu Dayyeh, Saurabh Mukewar, Shounak Majumder, Raja Zaghlol, Eric J. Vargas Valls, Fateh Bazerbachi, Michael J. Levy, Todd H. Baron, Christopher J. Gostout, Bret T. Petersen, John Martin, Ferga C. Gleeson, Randall K. Pearson, Suresh T. Chari, Santhi S. Vege, Mark D. Topazian
    Large-caliber metal stents versus plastic stents for the management of pancreatic walled-off necrosis
    Symptomatic pancreatic walled-off necrosis (WON) may be managed by endoscopic transmural drainage and endoscopic transmural necrosectomy, with stent placement at endoscopic drainage sites. The optimal stent choice is yet to be determined. We compared outcomes after endoscopic management of WON using either large-caliber fully covered self-expandable metal stents (LC-SEMSs) or double-pigtail plastic stents (DPPSs).


    Date de mise en ligne : Mardi 02 mai 2017
    Timothy D. Imler, Stuart Sherman, Thomas F. Imperiale, Huiping Xu, Fangqian Ouyang, Christopher Beesley, Charity Hilton, Gregory A. Coté
    Provider-specific quality measurement for ERCP using natural language processing
    Natural language processing (NLP) is an information retrieval technique that has been shown to accurately identify quality measures for colonoscopy. There are no systematic methods by which to track adherence to quality measures for ERCP, the highest risk endoscopic procedure widely used in practice. Our aim was to demonstrate the feasibility of using NLP to measure adherence to ERCP quality indicators across individual providers.


    Date de mise en ligne : Vendredi 28 avril 2017
    Michael Dougherty, Thomas M. Runge, Swathi Eluri, Evan S. Dellon
    Esophageal dilation with either bougie or balloon technique as a treatment for eosinophilic esophagitis: a systematic review and meta-analysis
    Esophageal dilation is a now recognized to be an important therapeutic modality in eosinophilic esophagitis (EoE). We aimed to evaluate the safety of esophageal dilation in EoE, especially regarding perforation risk, and to examine perforation risk by dilator type.


    Date de mise en ligne : Vendredi 28 avril 2017
    Carlos Robles-Medranda, Miguel Puga-Tejada, Jesenia Ospina, Manuel Valero, Hannah Pitanga Lukashok
    Over-the-scope clip in the management of fibrotic esophageal variceal bleeding (with video)
    We report the feasibility and technical success of the over-the-scope clip (OTSC) (Ovesco Endoscopy AG, Tuebingen, Germany) in the mechanical closure of esophageal variceal bleeding (VB) in a cirrhotic patient with variceal wall disruption associated with fibrosis secondary to long-term treatment of endoscopy band ligation (EBL).


    Date de mise en ligne : Vendredi 28 avril 2017
    Eddie Y. Liu, Paul J. Belletrutti
    Isolated esophageal tears from deceleration trauma
    A 30-year-old woman, while snowboarding, fell 15 feet from a jump onto hard-packed snow and sustained soft tissue injuries to her left hip and chest wall. Forty-eight hours later, she experienced retrosternal pleuritic chest pain and progressive odynophagia. An empirical trial with a proton-pump inhibitor (PPI) for 5 days did not resolve her symptoms. Medical evaluation 10 days later revealed unremarkable results of physical examination, no fever, and a normal white blood count. CT of the chest and abdomen showed no abnormalities.


    Date de mise en ligne : Mardi 25 avril 2017
    James P. Moriarty, Nilay D. Shah, Joel H. Rubenstein, Christopher H. Blevins, Michele Johnson, David A. Katzka, Kenneth K. Wang, Louis Michel Wongkeesong, David A. Ahlquist, Prasad G. Iyer
    Costs associated with Barrett’s esophagus screening in the community: an economic analysis of a prospective randomized controlled trial of sedated versus hospital unsedated versus mobile community unsedated endoscopy
    Data on the economic impact associated with screening for Barrett’s esophagus (BE) are limited. As part of a comparative effectiveness randomized trial of unsedated transnasal endoscopy (uTNE) and sedated EGD (sEGD), we assessed costs associated with BE screening.


    Date de mise en ligne : Mardi 25 avril 2017
    Kamar Belghazi, Frederike G.I. van Vilsteren, Bas L.A.M. Weusten, Sybren L. Meijer, Jacques J.G.H.M. Bergman, Roos E. Pouw
    Long-term follow-up results of stepwise radical endoscopic resection for Barrett’s esophagus with early neoplasia
    Stepwise radical endoscopic resection (SRER) has shown to be effective in eradicating Barrett’s esophagus (BE) and its associated dysplasia. The aim of this study was to assess the long-term durability after successful SRER for early Barrett’s neoplasia.


    Date de mise en ligne : Mardi 25 avril 2017
    Rachel S. van der Post, Jolanda van Dieren, Anna Grelack, Nicoline Hoogerbrugge, Lizet E. van der Kolk, Petur Snaebjornsson, Iris Lansdorp-Vogelaar, J. Han van Krieken, Tanya M. Bisseling, Annemieke Cats
    Outcomes of screening gastroscopy in first-degree relatives of patients fulfilling hereditary diffuse gastric cancer criteria
    The aim of this study was to determine the yield of endoscopic screening in first-degree relatives (FDRs) of CDH1-negative hereditary diffuse-type gastric cancer (HDGC) patients.


    Date de mise en ligne : Mardi 25 avril 2017
    Peter B. Cotton, Qi Pauls, Jamila Keith, Andre Thornhill, Douglas Drossman, April Williams, Valerie Durkalski-Mauldin
    The EPISOD study: long-term outcomes
    The EPISOD (Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction) study randomized patients with post-cholecystectomy pain, and little or no objective evidence for biliary obstruction, to sphincterotomy or sham intervention. Results at 1 year showed no benefit for the active treatment. We now report the outcomes at up to 5 years.


    Date de mise en ligne : Mardi 25 avril 2017
    Fernanda Prata Martins, Gustavo Andrade De Paulo, MĂŽnica L.C. Contini, Angelo Paulo Ferrari
    Metal versus plastic stents for anastomotic biliary strictures after liver transplantation: a randomized controlled trial
    Biliary anastomotic stricture occurs in 15% to 20% of patients after deceased orthotopic liver transplantation (OLT). It is usually treated endoscopically with multiple plastic stents (MPSs), although the use of fully covered self-expandable metal stents (cSEMSs) is emerging. This study aims to compare the efficacy and safety of cSEMSs versus MPSs in these patients.


    Date de mise en ligne : Jeudi 20 avril 2017
    Ming Tan, Ove B. Schaffalitzky de Muckadell, Stig B. Laursen
    Association between early ERCP and mortality in patients with acute cholangitis
    Acute cholangitis (AC) is associated with high mortality of up to 10%. The association between timing of ERCP and mortality in patients with AC remains unclear. The aim of this study was to investigate whether early ERCP within 24 hours was associated with improved survival.


    Date de mise en ligne : Jeudi 20 avril 2017
    Jennifer H. Lai, Gavin Park, Lauren B. Gerson
    Association between breast cancer and the risk of colorectal cancer
    The literature to date has suggested a potential increase in colorectal cancer (CRC) among patients with breast cancer.


    Date de mise en ligne : Jeudi 20 avril 2017
    Luca Elli, Giovanni Casazza, Martina Locatelli, Federica Branchi, Francesca Ferretti, Dario Conte, Mirella Fraquelli
    Use of enteroscopy for the detection of malignant and premalignant lesions of the small bowel in complicated celiac disease: a meta-analysis
    Enteroscopy (wireless or wired) is the reference standard for small-bowel (SB) diseases, and it has been applied to detect SB malignancies in complicated celiac disease (CD) with heterogeneous results. The aim of this meta-analysis was to obtain a diagnostic yield (DY) by pooling the data of studies that investigated the use of enteroscopy to detect SB adverse events in CD.


    Date de mise en ligne : Mardi 18 avril 2017
    Chen Chen, Christian Stock, Michael Hoffmeister, Hermann Brenner
    Public health impact of colonoscopy use on colorectal cancer mortality in Germany and the United States
    Colonoscopy has been demonstrated to be effective in reducing colorectal cancer (CRC) incidence and mortality and has been widely used for primary CRC screening in Germany and the United States. We performed a population-based analysis to evaluate and compare the public health impact of recent colonoscopy use on CRC deaths among adults aged 55 to 79 years in Germany and the United States from 2008 to 2011.


    Date de mise en ligne : Mardi 18 avril 2017
    Hee Seung Lee, Sung Bae Kim, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim
    Postoperative adjuvant chemotherapy is associated with a lower incidence of colorectal adenomas in patients with previous colorectal cancer
    The effects of chemotherapeutic agents on the development of colorectal adenomas in patients with previous colorectal cancer (CRC) are not defined. Therefore, we evaluated the potential effect of adjuvant chemotherapy on the incidence of colorectal adenomas in patients with previous CRC.


    Date de mise en ligne : Jeudi 13 avril 2017
    Zacharias P. Tsiamoulos, Ravi Misra, Rajaratanam Rameshshanker, Timothy R. Elliott, Iosif Beintaris, Siwan Thomas-Gibson, Adam Haycock, Noriko Suzuki, Colin Rees, Brian P. Saunders
    Impact of a new distal attachment on colonoscopy performance in an academic screening center
    Distal attachments placed on the colonoscope tip may positively affect performance by assisting insertion and polyp detection. The original Endocuff (ARC Medical Design, Leeds, United Kingdom) appears to improve adenoma detection rate (ADR), but no data assess the performance of the second-generation Endocuff Vision.


    Date de mise en ligne : Lundi 10 avril 2017
    Anne F. Peery, Nicholas J. Shaheen, Katherine S. Cools, Todd H. Baron, Mark Koruda, Joseph A. Galanko, Ian S. Grimm
    Morbidity and mortality after surgery for nonmalignant colorectal polyps
    Despite evidence that most nonmalignant colorectal polyps can be managed endoscopically, a substantial proportion of patients with a nonmalignant colorectal polyp are still sent to surgery. Risks associated with this surgery are not well characterized. We describe 30-day postoperative morbidity and mortality and explore risk factors for adverse events in patients undergoing surgical resection for nonmalignant colorectal polyps.


    Date de mise en ligne : Vendredi 07 avril 2017
    Loren Laine, Stig B. Laursen, Harry R. Dalton, Jing H. Ngu, Michael Schultz, Adrian J. Stanley
    Relationship of time to presentation after onset of upper GI bleeding with patient characteristics and outcomes: a prospective study
    We performed a prospective multi-national study of patients presenting to the emergency department with upper GI bleeding (UGIB) and assessed the relationship of time to presentation after onset of UGIB symptoms with patient characteristics and outcomes.


    Date de mise en ligne : Vendredi 07 avril 2017
    Douglas K. Rex, Cesare Hassan, Michael J. Bourke
    The colonoscopist's guide to the vocabulary of colorectal neoplasia: histology, morphology, and management
    Prevention of colorectal cancer by colonoscopy requires an effective and safe insertion technique, a high level of detection of pre-cancerous lesions, and skillful use of curative endoscopic resection techniques. Lesion detection, characterization, use of appropriate resection methods, prediction of cancer at colonoscopy, and management of malignant polyps all depend on an accurate and complete understanding of an extensive vocabulary describing the histology and morphology of neoplastic colorectal lesions.


    Date de mise en ligne : Vendredi 07 avril 2017
    Benjamin L. Bick, Thomas F. Imperiale, Cynthia S. Johnson, John M. DeWitt
    Endoscopic suturing of esophageal fully covered self-expanding metal stents reduces rates of stent migration
    Endoscopic suturing of fully covered self-expanding metal stents (FC-SEMSs) may prevent migration. The aim of this study was to compare rates of migration between sutured FC-SEMSs (S-FCSEMSs), unsecured FC-SEMSs, and partially covered SEMSs (PC-SEMSs) placed for benign esophageal leaks and strictures.


    Date de mise en ligne : Vendredi 07 avril 2017
    Nisa Netinatsunton, Jaksin Sottisuporn, Siriboon Attasaranya, Teepawit Witeerungrot, Aroon Siripun, Tanawat Pattarapuntakul, Bancha Ovartlarnporn
    Prospective randomized trial of EUS-assisted ERCP without fluoroscopy versus ERCP in common bile duct stones
    ERCP with stone removal is the standard treatment for common bile duct stones (CBDSs). Radiation exposure is a risk to the endoscopist and patient. EUS-guided ERCP without fluoroscopy (EGEWF) in patients with CBDSs is feasible, but the efficacy and safety compared with ERCP is unknown. We aimed to compare the efficacy and safety of EGEWF with ERCP in CBDS removal.


    Date de mise en ligne : Vendredi 07 avril 2017
    Ye Han, Jintao Guo, Siyu Sun, Weichao Wu, Sheng Wang, Nan Ge, Xiang Liu, Guoxin Wang, Shupeng Wang
    Acellular dermal matrix for esophageal stricture prevention after endoscopic submucosal dissection in a porcine model
    Endoscopic submucosal dissection (ESD) is considered an effective treatment for early esophageal cancer and precancerous lesions. Esophageal stenosis is closely associated with quasi-circumferential ESD. We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane.


    Date de mise en ligne : Jeudi 06 avril 2017
    Sung Yong Han, Gwang Ha Kim
    Collision tumor arising from a gastric duplication cyst
    A 41-year-old woman presented with a gastric subepithelial lesion. Upper endoscopy revealed a 6-cm subepithelial mass with surface erosions at the posterior wall of the upper body of the stomach (A). Endoscopic ultrasonography revealed a homogenous cystic lesion with inner mucus debris and a solid mass in the periphery, which invaded the pancreatic tail (B, arrow). Total gastrectomy and distal pancreatectomy were performed. The cyst was located in the muscularis propria of the stomach (C, arrowhead), and a histopathologic examination showed that the cystic space was lined by columnar or squamous epithelial mucosa.


    Date de mise en ligne : Jeudi 06 avril 2017
    Alberto Arezzo, Roberto Passera, Giacomo Lo Secco, Mauro Verra, Marco Augusto Bonino, Eduardo Targarona, Mario Morino
    Stent as bridge to surgery for left-sided malignant colonic obstruction reduces adverse events and stoma rate compared with emergency surgery: results of a systematic review and meta-analysis of randomized controlled trials
    Twenty years after the first description of the technique, the debate is still open on the role of self-expandable metallic stent (SEMS) placement as a bridge to elective surgery for symptomatic left-sided malignant colonic obstruction. The aim was to compare morbidity rates after colonic stenting bridge to surgery (SBTS) versus emergency surgery (ES) for left-sided malignant obstruction.


    Date de mise en ligne : Jeudi 06 avril 2017
    Yasser Shaib, Lara Hassoun
    Double-lumen duodenum
    A 33-year-old man with a history of Hodgkin lymphoma was seen 92 days after allogenic stem cell transplantation; he presented with a 5-day history of large-volume watery diarrhea. The results of laboratory evaluation and stool studies were noncontributory. Flexible sigmoidoscopy with examination of biopsy specimens revealed mild chronic colitis with no evidence of graft-versus-host disease (GVHD). Nevertheless, the patient was given systemic and nonabsorbable steroid agents. However, he continued to have large-volume diarrhea, worsening anorexia, and malnutrition.


    Date de mise en ligne : Mardi 04 avril 2017
    Antonio D’Antonio, Patrizia Borgheresi, Maria Addesso
    An unexpected adverse event of gastric bypass: giant hyperplastic polyp showing an intramucosal adenocarcinoma
    A 58-year-old woman underwent a gastroscopy for iron deficiency anemia, epigastric pain, outlet obstruction, and abdominal distension. The patient had undergone open gastric bypass 4 years earlier because of morbid obesity. The gastroscopy showed a pedunculated 8-cm polyp with a thick stalk on the anterior wall of the antrum (A). The polyp surface appeared composed of multiple villous-like projections with a smooth surface (B). Examination of repeated biopsy specimens from the polypoid lesion showed a hyperplastic polyp.


    Date de mise en ligne : Mardi 04 avril 2017
    Douglas G. Adler
    Use of a lumen-apposing metal stent to treat pyloric stenosis
    A 77-year-old woman with a 100 pack/year history of tobacco use presented to our center with failure to thrive, weight loss, and intolerance of oral intake. Chest, abdominal, and pelvic CT revealed multiple lung masses and liver metastases. Examination of a biopsy specimen from her lung mass revealed squamous cell carcinoma of the lung. A positron emission tomography scan did not show hypermetabolic activity at the pylorus. An EGD was performed to investigate her eating issues and revealed a high-grade stenosis of her pylorus with an overall benign appearance suggestive of scarring secondary to prior peptic ulcer disease (A).


    Date de mise en ligne : Mardi 04 avril 2017
    Harry D.S. Soar, Muhammad H. Shiwani
    Successful endoscopic removal of a telescopic radio aerial from the stomach
    Ingestion of a foreign body is a common reason for attendance at the emergency department. Each case provides a unique challenge depending on the size, shape, and consistency of the object swallowed. We present a challenging case of a rarely ingested and unusually shaped object: a telescopic radio aerial and the techniques we used to successfully manage it. A 23-year-old woman from a local psychiatric hospital had swallowed a biro pen and a metal telescopic radio aerial that she had broken off from an FM radio.


    Date de mise en ligne : Lundi 03 avril 2017
    Luis F. Lara, Morihito Takita, James S. Burdick, Daniel C. DeMarco, Ronnie R. Pimentel, Tolga Erim, Marlon F. Levy
    A study of the clinical utility of a 20-minute secretin-stimulated endoscopic pancreas function test and performance according to clinical variables
    Direct pancreas juice testing of bicarbonate, lipase, or trypsin after stimulation by secretin or cholecystokinin is used to determine exocrine function, a surrogate for diagnosing chronic pancreatitis (CP). Endoscopic pancreas function tests (ePFTs), where a peak bicarbonate concentration (PBC) ≄80 mEq/L in pancreas juice is considered normal, are now used more frequently. In this ePFT, aspirates start 35 minutes after secretin administration because pancreas output peaks 30 minutes after secretagogue administration.


    Date de mise en ligne : Lundi 03 avril 2017
    Yoon Suk Jung, Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn
    Colorectal cancer screening with the fecal immunochemical test in persons aged 30 to 49 years: focusing on the age for commencing screening
    The fecal immunochemical test (FIT) can be an alternative screening method for colorectal cancer in individuals aged <50 years. However, debate continues concerning the age at which commencing FIT is beneficial.


    Date de mise en ligne : Samedi 01 avril 2017
    Navin L. Kumar, Brian L. Claggett, Aaron J. Cohen, Jennifer Nayor, John R. Saltzman
    Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding
    An increase in blood urea nitrogen (BUN) at 24 hours is a solitary and significant predictor of mortality in patients with acute pancreatitis, which may predict worse outcomes in the similarly resuscitation-requiring condition of acute nonvariceal upper GI bleeding (UGIB). The aim of our study was to assess whether an increase in BUN at 24 hours is predictive of worse clinical outcomes in acute nonvariceal UGIB.


    Date de mise en ligne : Jeudi 30 mars 2017
    Peter B. Cotton, Derek Feussner, Darin Dufault, Gregory Cote
    A survey of credentialing for ERCP in the United States
    There are limited data measuring the variability in standards used by hospitals for credentialing physicians to ERCP in the United States.


    Date de mise en ligne : Jeudi 30 mars 2017
    Samir C. Grover, Michael A. Scaffidi, Rishad Khan, Ankit Garg, Ahmed Al-Mazroui, Tareq Alomani, Jeffrey J. Yu, Ian S. Plener, Mohamed Al-Awamy, Elaine L. Yong, Maria Cino, Nikila C. Ravindran, Mark Zasowski, Teodor P. Grantcharov, Catharine M. Walsh
    Progressive learning in endoscopy simulation training improves clinical performance: a blinded randomized trial
    A structured comprehensive curriculum (SCC) that uses simulation-based training (SBT) can improve clinical colonoscopy performance. This curriculum may be enhanced through the application of progressive learning, a training strategy centered on incrementally challenging learners. We aimed to determine whether a progressive learning-based curriculum (PLC) would lead to superior clinical performance compared with an SCC.


    Date de mise en ligne : Jeudi 30 mars 2017
    James L. Buxbaum, David Hormozdi, Mario Dinis-Ribeiro, Christianne Lane, Diogo Dias-Silva, Ara Sahakian, Preeth Jayaram, Pedro Pimentel-Nunes, Daniel Shue, Michael Pepper, Daniel Cho, Loren Laine
    Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial
    Gastric intestinal metaplasia (GIM) is a gastric cancer precursor. Narrow-band imaging (NBI) may improve detection of GIM. We compared detection of GIM with high-definition white-light (HD-WL) endoscopy, NBI, and mapping biopsies in a population with increased gastric cancer risk.


    Date de mise en ligne : Mercredi 29 mars 2017
    Enqiang Linghu, Chen Du, Ningli Chai, Huikai Li, Zhiqiang Wang, Yufa Sun, Wei Xu, Xu Guo, Bo Ning, Lihua Sun, Wei Zhang, Xiangdong Wang, Ping Tang, Jia Feng
    A prospective study on the safety and effectiveness of using lauromacrogol for ablation of pancreatic cystic neoplasms with the aid of EUS
    With the development of imaging techniques, the detection rate of pancreatic cystic neoplasms (PCNs) has increased. The surgical morbidity and mortality rates of PCNs are quite high. This study is intended to evaluate the safety and effectiveness of a minimally invasive treatment, EUS-guided PCN ablation with lauromacrogol.


    Date de mise en ligne : Mercredi 29 mars 2017
    Madhav Desai, Andre Sanchez-Yague, Abhishek Choudhary, Asad Pervez, Neil Gupta, Prashanth Vennalaganti, Sreekar Vennelaganti, Alessandro Fugazza, Alessandro Repici, Cesare Hassan, Prateek Sharma
    Impact of cap-assisted colonoscopy on detection of proximal colon adenomas: systematic review and meta-analysis
    Proximal colon adenomas can be missed during routine colonoscopy. Use of a cap or hood on the tip of the colonoscope has been shown to improve overall adenoma detection with variable rates. However, it has not been systematically evaluated for detection of proximal colon or right-sided adenomas where the cap may have maximum impact on adenoma detection rate (ADR). Our aim was to perform a systematic review and meta-analysis to evaluate the impact of cap-assisted colonoscopy (CC) on right-sided ADRs (r-ADRs) compared with standard colonoscopy (SC).


    Date de mise en ligne : Mercredi 22 mars 2017
    Yuta Koike
    A rare cause of recurrent acute pancreatitis: duodenum intussusception by a fenestrated duodenal web
    A 13-year-old boy presented with a body weight that was low for his age; he had experienced repeated vomiting episodes and acute pancreatitis of an unknown cause since he was 9 years old. When acute pancreatitis developed for the fifth time, CT of the abdomen revealed severe acute pancreatitis with a duodenum-within-duodenum configuration, indicating the second portion of a duodenal intussusception (A). Duodenal intussusception prevented the normal flow of pancreatic enzymes, which may have caused the acute pancreatitis.


    Date de mise en ligne : Mercredi 22 mars 2017
    Mathew Keegan, Rooshdiya Karim, Arthur Kaffes, Payal Saxena
    A welcome diagnosis for painless biliary dilatation (with video)
    A 59-year-old man presented with acute functional decline and painless liver biochemistry derangement: elevation of aspartate aminotransferase 160 IU/L, alanine aminotransferase 71 IU/L, and γ-glutamyl transferase 63 IU/L, with normal levels of bilirubin and alkaline phosphate. A CT scan demonstrated a 10-mm hypodensity at the ampulla of Vater associated with a prominent extrahepatic biliary duct (A). Assessment with a duodenoscope revealed a bulky ampulla. Normal-appearing overlying mucosa was confirmed on histopathologic examination.


    Date de mise en ligne : Mercredi 22 mars 2017
    Sinkeet Ranketi, Michael Mwachiro, Mark Topazian, Stephen Burgert
    Endoscopic treatment of cervical esophageal transluminal bridge
    A 27-year-old woman presented with dysphagia. She had undergone endoscopic dilation of an idiopathic esophageal stricture at 5 years of age, and she had been swallowing well until 1 month before presentation. EGD revealed a mild stricture at 18 cm from the incisors, a midluminal transverse esophageal mucosal bridge at 20 cm (A), and a tight distal stricture at 30 cm, which was serially dilated over a guidewire with the use of Savary dilators of sizes 18F, 21F, and 24F diameter. The endoscope was then able to advance, and no mucosal injuries were noted.


    Date de mise en ligne : Dimanche 19 mars 2017
    Shani Woolard, Paula Adamson, Emad Qayed
    Esophageal fibrous band causing dysphagia in an HIV+ patient
    A 40-year-old man with a history of HIV/AIDS presented with persistent dysphagia. He had undergone multiple upper endoscopies over the previous year because of dysphagia and odynophagia and had been found to have recurrent idiopathic HIV-associated esophageal ulcers, which required dilations and thalidomide administration. The patient then underwent a repeat upper endoscopy, which showed healed esophageal ulcers and a 5-cm-long band of fibrous tissue in the distal esophagus (A). The proximal and distal ends of the band were located 30 cm and 35 cm, respectively, from the incisors.


    Date de mise en ligne : Samedi 18 mars 2017
    Min Min, Yiliang Bi, Yan Liu, Yang Xu
    Extramedullary gastric relapse of acute lymphoblastic leukemia in an adolescent
    A 16-year-old girl who had undergone hemopoietic stem cell transplantation for acute lymphoblastic leukemia (ALL) 2 years earlier presented with epigastric pain and diarrhea of 1 month’s duration. The full blood count showed normal results. Upper GI endoscopy revealed flat elevated lesions in the greater curvature of the gastric body (A, B). Histopathologic study revealed infiltration of the lamina propria with neoplastic lymphoid cells. Immunohistochemical analysis showed expression of CD3, CD79a, and PAX-5; and Ki-67 was 90% of the cells (C, D).


    Date de mise en ligne : Samedi 18 mars 2017
    Saad A. Khan, Jeremy P. Dwyer, Rhys Vaughan
    Peritoneal carcinomatosis from signet-ring cell adenocarcinoma of the appendix
    A 50-year-old man was seen because of 6 weeks of generalized abdominal pain, anorexia, weight loss, and constipation. CT of the abdomen revealed a large amount of intraperitoneal fluid and nodular, striated soft tissue within the fat anterior to the transverse colon (A), consistent with peritoneal carcinomatosis. No primary site of malignancy or evidence of distant metastases was identified. Tumor marker CA19-9 was elevated at 381 kU/L (normal, <37 kU/L), and the carcinoembryonic antigen level was normal.


    Date de mise en ligne : Samedi 18 mars 2017
    Marietta Iacucci, Marco Daperno, Mark Lazarev, Razvan Arsenascu, Gian Eugenio Tontini, Oluseyi Akinola, Xianyong Sean Gui, Vincenzo Villanacci, Martin Goetz, Mark Lowerison, Brendan Cord Lethebe, Maurizio Vecchi, Helmut Neumann, Subrata Ghosh, Raf Bisschops, Ralf Kiesslich
    Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis
    Endoscopic inflammation and healing are important therapeutic endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual chromoendoscopy (EVC) score that could reflect the full spectrum of mucosal and vascular changes including mucosal healing in UC.


    Date de mise en ligne : Samedi 18 mars 2017
    Anne-Fré Swager, Fons van der Sommen, Sander R. Klomp, Sveta Zinger, Sybren L. Meijer, Erik J. Schoon, Jacques J.G.H.M. Bergman, Peter H. de With, Wouter L. Curvers
    Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy
    Volumetric laser endomicroscopy (VLE) is an advanced imaging system that provides a near-microscopic resolution scan of the esophageal wall layers up to 3-mm deep. VLE has the potential to improve detection of early neoplasia in Barrett’s esophagus (BE). However, interpretation of VLE images is complex because of the large amount of data that need to be interpreted in real time. The aim of this study was to investigate the feasibility of a computer algorithm to identify early BE neoplasia on ex vivo VLE images.


    Date de mise en ligne : Lundi 13 mars 2017
    Andrea Oliver Tal, Fabian Finkelmeier, Natalie Filmann, Leena KylĂ€npÀÀ, Marianne Udd, Ilaria Parzanese, Paolo CantĂč, Alexander DechĂȘne, Volker Penndorf, Andreas Schnitzbauer, Mireen Friedrich-Rust, Stefan Zeuzem, Jörg G. Albert
    Multiple plastic stents versus covered metal stent for treatment of anastomotic biliary strictures after liver transplantation: a prospective, randomized, multicenter trial
    Treatment of anastomotic biliary strictures (ABSs) after orthotopic liver transplantation by endoscopic insertion of multiple plastic stents (MPSs) is well established. The use of covered self-expandable metal stents (cSEMSs) for this indication is less investigated.


    Date de mise en ligne : Vendredi 10 mars 2017
    Hae Won Kim, Jie-Hyun Kim, Jun Chul Park, Mi Young Jeon, Yong Chan Lee, Sang Kil Lee, Sung Kwan Shin, Hyun Soo Chung, Sung Hoon Noh, Jong Won Kim, Seung Ho Choi, Jae Jun Park, Young Hoon Youn, Hyojin Park
    Additive endoscopic resection may be sufficient for patients with a positive lateral margin after endoscopic resection of early gastric cancer
    No well-established treatment strategies exist for lateral margin positivity (LM+) alone after endoscopic resection (ER) of early gastric cancer (EGC). Thus, we aimed to clarify a treatment strategy for non-curative resection (non-CR) with LM+ alone after ER in EGC.


    Date de mise en ligne : Vendredi 10 mars 2017
    Wenjie Liu, Min Wang, Lili Zhao, Min Wang, Xiang Wang, Zhining Fan, Li Liu
    Thermo-sensitive isopentane aerification for mucosal lift during endoscopic resection in animal models (with video)
    Mucosal lift is critical for successful endoscopic treatment. Normal saline (NS) solution is widely used as the submucosal filler, but its short persistency restricts clinical endoscopic submucosal dissection (ESD). In this study, thermo-sensitive isopentane was introduced for submucosal injection. With a boiling point at 27.8°C, liquid isopentane can be easily applied, and gasification inflation can provide great support for submucosal lifting at body temperature. The feasibility and efficiency of isopentane were evaluated in this study.


    Date de mise en ligne : Jeudi 09 mars 2017
    Min Min, Pei Deng, Wenhua Zhang, Xiaomin Sun, Yan Liu, Bing Nong
    Comparison of linked color imaging and white-light colonoscopy for detection of colorectal polyps: a multicenter, randomized, crossover trial
    Linked color imaging (LCI), a recently developed technology, uses a laser endoscopic system to enhance the color separation of red color to depict red and white colors more vividly. The benefits of LCI in the detection of colorectal polyps remain unknown. The aim of this study was to assess the ability of LCI to improve the detection of colorectal polyps compared with white-light (WL) endoscopy.


    Date de mise en ligne : Jeudi 09 mars 2017
    Somashekar G. Krishna, William R. Brugge, John M. Dewitt, Pradermchai Kongkam, Bertrand Napoleon, Carlos Robles-Medranda, Damien Tan, Samer El-Dika, Sean McCarthy, Jon Walker, Mary E. Dillhoff, Andrei Manilchuk, Carl Schmidt, Benjamin Swanson, Zarine K. Shah, Phil A. Hart, Darwin L. Conwell
    Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos)
    EUS-guided needle-based confocal laser endomicroscopy (nCLE) characteristics of common types of pancreatic cystic lesions (PCLs) have been identified; however, surgical histopathology was available in a minority of cases. We sought to assess the performance characteristics of EUS nCLE for differentiating mucinous from non-mucinous PCLs in a larger series of patients with a definitive diagnosis.


    Date de mise en ligne : Jeudi 09 mars 2017
    Rui Huang, Hongwei Cai, Xin Zhao, Xiaoqiang Lu, Min Liu, Wenhao Lv, Zhiguo Liu, Kaichun Wu, Ying Han
    Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma: a propensity score matching analysis
    Esophageal endoscopic submucosal dissection (ESD) is technically challenging because of the thinner wall and narrow lumen. The tunnel technique was proposed previously. This current retrospective study aimed to evaluate the efficacy of the tunnel technique in ESD of superficial esophageal squamous cell carcinoma (ESCC).


    Date de mise en ligne : Mercredi 08 mars 2017
    Orly Sneh Arbib, Valentina Zemser, Yaara Leibovici Weissman, Rachel Gingold-Belfer, Alex Vilkin, Sapir Eizenstein, Arnon Cohen, Doron Comaneshter, Shochat Tzipora, Yaron Niv, Yeuda Ringel, David Lieberman, Zohar Levi
    Risk of advanced lesions at the first follow-up colonoscopy after polypectomy of diminutive versus small adenomatous polyps of low-grade dysplasia
    The current guidelines for surveillance after polypectomy do not distinguish between diminutive (1-5 mm) and small (6-9 mm) polyps with low-grade dysplasia (LGD). We aimed to evaluate the risk for advanced neoplasia on follow-up colonoscopy.


    Date de mise en ligne : Mercredi 08 mars 2017
    Mi Gang Kim, Se Woo Park, Jae Hyun Kim, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi
    Etomidate versus propofol sedation for complex upper endoscopic procedures: a prospective double-blinded randomized controlled trial
    Although a growing body of evidence demonstrates that propofol-induced deep sedation can be effective and performed safely, cardiopulmonary adverse events have been observed frequently. Etomidate is a new emerging drug that provides hemodynamic and respiratory stability, even in high-risk patient groups. The objective of this study was to compare safety and efficacy profiles of etomidate and propofol for endoscopic sedation.


    Date de mise en ligne : Mardi 07 mars 2017
    Dina S. Ahmad, Khalid Sahak, Audrey J. Lazenby, Ishfaq Bhat
    Chronic mesenteric ischemia and gastric ischemia: a bad combination
    An 83-year-old woman with a medical history significant for atrial fibrillation, type 2 diabetes, and chronic obstructive pulmonary disease (COPD) presented with diffuse postprandial abdominal pain, nausea, and vomiting. The results of her examination were significant for moderate epigastric abdominal tenderness. CT of the abdomen without contrast medium revealed extensive calcific atherosclerotic disease of the abdominal aorta. Magnetic resonance angiography showed advanced atherosclerotic vascular disease with high-grade stenosis at the origin of the celiac artery and high-grade narrowing at the origin of the superior mesenteric artery (SMA) (A).


    Date de mise en ligne : Dimanche 05 mars 2017
    Nicolas Musquer, Merzouka Zidane-Marinnes, Mamoun Dib
    Primary mucosa-associated lymphoid tissue lymphoma of the entire esophagus
    An 85-year-old man with no medical history of digestive disease was admitted for dysphagia. A gastroscopy revealed, despite sufficient insufflation, a narrowing of the entire esophagus lumen with normal mucosa (A). Deep biopsies (bite-on-bite biopsies) were performed with conventional-sized biopsy forceps. Chest CT showed an important thickening of the entire esophageal wall (B). EUS confirmed this regular thickening without lymph node metastasis. Histopathologic examination showed an important submucosal infiltration of lymphocytes with B cell markers (CD20+/CD10−) (C) corresponding to a mucosa-associated lymphoid tissue lymphoma (MALT) of the esophagus.


    Date de mise en ligne : Mercredi 01 mars 2017
    Markus Dollhopf, Alberto Larghi, Uwe Will, Mihai RimbaƟ, Andrea Anderloni, Andres Sanchez-Yague, Anthony Yuen Bun Teoh, Rastislav Kunda
    EUS-guided gallbladder drainage in patients with acute cholecystitis and high surgical risk using an electrocautery-enhanced lumen-apposing metal stent device
    In high-risk surgical patients, the treatment of choice of acute cholecystitis is percutaneous transhepatic gallbladder drainage (PTGBD). Recently, a novel endoscopic device containing a lumen-apposing metal stent with an electrocautery (ECE-LAMS) on the tip has been developed.


    Date de mise en ligne : Mercredi 01 mars 2017
    Masaya Suenaga, Yoshihiko Sadakari, Jose Alejandro Almario, Michael Borges, Anne-Marie Lennon, Eun-Ji Shin, Marcia Irene Canto, Michael Goggins
    Using an endoscopic distal cap to collect pancreatic fluid from the ampulla (with video)
    Duodenal collections of pancreatic fluid can be used as a source of mutations and other markers of pancreatic ductal neoplasia, but admixing pancreatic juice with duodenal contents lowers the concentrations of mutations. Collecting pancreatic fluid directly from the ampulla could yield a purer sample of pancreatic fluid.


    Date de mise en ligne : Mardi 28 février 2017
    Laith H. Jamil, Amir Kashani, Neiveen Peter, Simon K. Lo
    Safety and efficacy of cap-assisted EMR for sporadic nonampullary duodenal adenomas
    Eradication of sporadic nonampullary duodenal adenomas (SNADAs) is essential because of their high rate of malignant transformation. EMR techniques are the alternative to the traditional surgical treatments of SNADAs. There are very limited data on the safety and efficacy of cap-assisted EMR (C-EMR) in the treatment of SNADA.


    Date de mise en ligne : Mardi 28 février 2017
    Kyoku Sumimoto, Shinji Tanaka, Kenjiro Shigita, Nana Hayashi, Daiki Hirano, Yuzuru Tamaru, Yuki Ninomiya, Shiro Oka, Koji Arihiro, Fumio Shimamoto, Masaharu Yoshihara, Kazuaki Chayama
    Diagnostic performance of Japan NBI Expert Team classification for differentiation among noninvasive, superficially invasive, and deeply invasive colorectal neoplasia
    The Japan NBI Expert Team (JNET) classification is the first universal narrow-band imaging magnifying endoscopic classification of colorectal tumors. Considering each type in this classification, the diagnostic ability of Type 2B is the weakest. Generally, clinical behavior is believed to be different in each gross type of colorectal tumor. We evaluated the differences in the diagnostic performance of JNET classification for each gross type (polypoid and superficial) and examined whether the diagnostic performance of Type 2B could be improved by subtyping.


    Date de mise en ligne : Jeudi 23 février 2017
    Riccardo Solimando, Alessandro Pezzoli, Viviana CifalĂ , Lucio Trevisani, Paolo Pazzi
    Unexpected finding after gastroduodenal artery embolization
    An 87-year-old woman with melena and anemia was admitted to the hospital and underwent urgent GI endoscopy. During the procedure, a large clot adhering to the posterior wall of the duodenal bulb was identified. Its removal with a retrieval net revealed an underlying visible vessel with active oozing (A). After an ineffective attempt to obtain endoscopic hemostasis with epinephrine injection, argon plasma coagulation, and clips, interventional radiology was performed. Selective arteriography of the celiac trunk revealed no extravasation, so blind embolization of the gastroduodenal artery with 3 platinum coils (SPIRALES.018″, coil ∅ 3 mm, coil length 5 cm; Balt Extrusion, Montmorency, France) was carried out (B, continous arrow: coil; dashed arrow: clip).


    Date de mise en ligne : Jeudi 23 février 2017
    Silvia Carrara, Milena Di Leo, Alessandro Repici
    Not only biliary but also ureteral stones can be detected by EUS
    A 61-year-old woman presented for EUS follow-up of anal squamous carcinoma. She had bilateral sponge kidney and had undergone interventional urological endoscopy for nephrocalcinosis. With the probe positioned 15 cm from the anal verge and oriented to the left anterior, an anechoic tubular structure (12 mm in diameter) was seen and was identified as the left ureter (A). By following the ureter, 3 stones (each 5 mm in length) with shadows were detected within the lumen (A, arrow) and at the entrance to the bladder.


    Date de mise en ligne : Jeudi 23 février 2017
    Rui Gaspar, Pedro Moutinho-Ribeiro, Guilherme Macedo
    Bullous pemphigoid: extensive esophageal involvement
    A 73-year-old woman with a medical history of bullous pemphigoid diagnosed in 2013, who was being treated with prednisolone 20 mg daily, was admitted to our internal medicine department with Escherichia coli urosepsis. She began treatment with ceftriaxone 2 g/day, and the dose of oral prednisolone was lowered to 10 mg/day.


    Date de mise en ligne : Jeudi 23 février 2017
    Ervin Alibegovic, Admir Kurtcehajic, Ahmed Hujdurovic, Adnan Zeco, Dzenita Kurtcehajic
    Acute submucosal hematoma: an adverse event of routine colonoscopy
    A 20-year-old woman underwent diagnostic colonoscopy because of nonspecific lower abdominal pain and problems with elimination (diarrhea and constipation). She had no history of any serious disease or surgery. Her body mass index was 20.2, and the results of physical examination were unremarkable. Her complete blood count was within normal limits, as were nonspecific inflammatory parameters (erythrocyte sedimentation rate, C-reactive protein). The values for biochemical tests including coagulation were within normal ranges.


    Date de mise en ligne : Jeudi 23 février 2017
    Xiaoyu Tang, Yuyong Tan, Deliang Liu
    Angiolipoma: a rare esophageal submucosal tumor
    A 50-year-old man came to our hospital with a 1-month history of chest discomfort. The discomfort increased while he was eating solid food, and he did not describe any retrosternal pain or acid regurgitation. There was no family history of GI cancer. The results of physical examination and laboratory tests were unremarkable. EGD revealed a soft columnar polypoid mass measuring 1.5 × 1.8 cm about 20 cm from the incisors (A), with normal overlying mucosa. EUS showed a homogeneous hyperechoic mass localized in the submucosal layer, without malignant features (B).


    Date de mise en ligne : Mardi 21 février 2017
    Yen-I Chen, Haruhiro Inoue, Michael Ujiki, Peter V. Draganov, Paul Colavita, Francois Mion, John Romanelli, Philip Chiu, Valerio Balassone, Lava Patel, Ali Abbas, Dennis Yang, Christy Dunst, Mathieu Pioche, Sabine Roman, JĂ©rĂŽme Rivory, Thierry Ponchon, David Desilets, Roberta Maselli, Manabu Onimaru, Jun Nakamura, Yoshitaka Hata, Gulara Hajiyeva, Amr Ismail, Saowanee Ngamruengphong, Majidah Bukhari, Yamile Haito Chavez, Vivek Kumbhari, Alessandro Repici, Mouen A. Khashab
    An international multicenter study evaluating the clinical efficacy and safety of per-oral endoscopic myotomy in octogenarians
    Per-oral endoscopic myotomy (POEM) for achalasia is particularly appealing in the elderly because it is minimally invasive. However, data in patients aged ≄80 years are scarce. The aim of this study was to assess the clinical outcome of POEM in octogenarians.


    Date de mise en ligne : Mardi 21 février 2017
    Fariha H. Ramay, Qingping Cui, Bruce D. Greenwald
    Outcomes after liquid nitrogen spray cryotherapy in Barrett's esophagus–associated high-grade dysplasia and intramucosal adenocarcinoma: 5-year follow-up
    Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett’s esophagus (BE)–associated high-grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking.


    Date de mise en ligne : Vendredi 10 février 2017
    Takuto Suzuki, Taro Hara, Yoshiyasu Kitagawa, Hideyuki Takashiro, Rino Nankinzan, Osamu Sugita, Taketo Yamaguchi
    Linked-color imaging improves endoscopic visibility of colorectal nongranular flat lesions
    As a newly developed image-enhanced endoscopy (IEE) technique, linked-color imaging (LCI) provides very bright images with enhanced color tones. With the objective of improving the detection rate of colorectal flat tumor lesions, which are difficult to detect, we examined the usefulness of LCI from the viewpoint of visibility.


    Date de mise en ligne : Mardi 07 février 2017
    Wouter F.W. Kappelle, Ronald L.A.W. Bleys, Albert J.M. van Wijck, Peter D. Siersema, Frank P. Vleggaar
    EUS-guided celiac ganglia neurolysis: a clinical and human cadaver study (with video)
    There is little evidence that structures targeted during EUS-guided celiac ganglia neurolysis (EUS-CGN) are celiac ganglia and that selective ethanol injection into ganglia is feasible. We aimed to visualize celiac ganglia, confirm that these structures are ganglia, and visualize ethanol spread after EUS-CGN and EUS-guided celiac plexus neurolysis (EUS-CPN).


    Date de mise en ligne : Mardi 07 février 2017
    Ankie Reumkens, Ad A. Masclee, Bjorn Winkens, Cees T. van Deursen, Silvia Sanduleanu, Christine M. Bakker
    Prevalence of hypokalemia before and after bowel preparation for colonoscopy in high-risk patients
    Bowel preparation for colonoscopy should not cause significant shifts in systemic electrolyte concentrations. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal consequences, prompting us to conduct a study to explore the magnitude of and risk factors for hypokalemia associated with bowel preparation. We paid specific attention to higher-risk subgroups, in particular, diuretic users, hospitalized patients, and patients estimated at to be high risk by the gastroenterologist.


    Date de mise en ligne : Samedi 04 février 2017
    Huiqin He, Chenfei Tan, Jiaguo Wu, Ning Dai, Weiling Hu, Yawen Zhang, Loren Laine, James Scheiman, John J. Kim
    Accuracy of ASGE high-risk criteria in evaluation of patients with suspected common bile duct stones
    ERCP is recommended for patients considered high risk for choledocholithiasis after biochemical testing and abdominal US. Our aim was to determine whether the American Society for Gastrointestinal Endoscopy (ASGE) guidelines accurately select patients for whom the risk of ERCP is justified.


    Date de mise en ligne : Samedi 04 février 2017
    Shozo Osera, Hiroaki Ikematsu, Satoshi Fujii, Keisuke Hori, Yasuhiro Oono, Tomonori Yano, Kazuhiro Kaneko
    Endoscopic treatment outcomes of laterally spreading tumors with a skirt (with video)
    A “skirt” is a slightly elevated flat lesion with wide pits occasionally observed at the margin of laterally spreading tumors (LSTs). However, the endoscopic treatment outcomes of LSTs with skirts have not been clarified. The aim of this study was to evaluate the endoscopic treatment outcomes of LSTs with skirts.


    Date de mise en ligne : Samedi 04 février 2017
    Tannaz Guivatchian, Erika S. Koeppe, Jason R. Baker, Cristina Moisa, Matthew Demerath, Caitlin Foor-Pessin, William D. Chey, Shanti L. Eswaran, Joseph C. Kolars, Stacy B. Menees, Michael Rajala, Michael D. Rice, Rafat Rizk, Joel H. Rubenstein, Pratima Sharma, Andrea Todisco, Elena M. Stoffel
    Family history in colonoscopy patients: feasibility and performance of electronic and paper-based surveys for colorectal cancer risk assessment in the outpatient setting
    Family history is crucial in stratifying patients’ risk for colorectal cancer (CRC). Previous risk assessment tools developed for use in clinic or endoscopy settings have demonstrated suboptimal specificity for identifying patients with hereditary cancer syndromes. Our aim was to test the feasibility and performance of 2 family history surveys (paper and electronic) in individuals presenting for outpatient colonoscopy.


    Date de mise en ligne : Vendredi 03 février 2017
    Hsiang-Chieh Lee, Osman O. Ahsen, Kaicheng Liang, Zhao Wang, Marisa Figueiredo, Michael G. Giacomelli, Benjamin Potsaid, Qin Huang, Hiroshi Mashimo, James G. Fujimoto
    Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus (with video)
    Angiogenesis is associated with neoplastic progression of Barrett’s esophagus (BE). Volumetric optical coherence tomography angiography (OCTA) visualizes subsurface microvasculature without exogenous contrast agents. We investigated the association of OCTA microvascular features with low-grade dysplasia (LGD) and high-grade dysplasia (HGD).


    Date de mise en ligne : Mercredi 01 février 2017
    Sunil Dacha, Parit Mekaroonkamol, Lianyong Li, Nikrad Shahnavaz, Sonali Sakaria, Steven Keilin, Field Willingham, Jennifer Christie, Qiang Cai
    Outcomes and quality-of-life assessment after gastric per-oral endoscopic pyloromyotomy (with video)
    Gastric per-oral endoscopic pyloromyotomy (GPOEM) is emerging as a promising option for the treatment of gastroparesis. This study assessed outcomes and quality of life after GPOEM for gastroparesis, performed in an endoscopy unit at a major tertiary referral center.


    Date de mise en ligne : Mercredi 01 février 2017
    A. Swager, A.J. de Groof, S.L. Meijer, B.L. Weusten, W.L. Curvers, Jacques J. Bergman
    Feasibility of laser marking in Barrett’s esophagus with volumetric laser endomicroscopy: first-in-man pilot study
    Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers and has potential to improve detection of neoplasia in Barrett’s esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks (LMs) in different esophageal tissue types on white light endoscopy (WLE) and VLE.


    Date de mise en ligne : Mercredi 01 février 2017
    Alessandro Repici, Roberta Maselli, Silvia Carrara, Andrea Anderloni, Markus Enderle, Cesare Hassan
    Standard needle versus needleless injection modality: animal study on different fluids for submucosal elevation
    Submucosal injection is currently used in GI endoscopy to reduce resection risks and to perform submucosal dissection; it is usually performed via an injection needle or a needleless device. The aim of the study was to compare 2 submucosal injection modalities (needle-assisted vs needleless) by using substances with different viscosities


    Date de mise en ligne : Mardi 31 janvier 2017
    Hamita Sachar, Nipaporn Pichetshote, Kavitha Nandigam, Keta Vaidya, Loren Laine
    Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial
    Current guidelines recommend diphenhydramine in patients undergoing endoscopy who are not adequately sedated with a benzodiazepine and opioid combination. Because this practice has not been adequately assessed, we performed a randomized, double-blind trial comparing diphenhydramine with continued midazolam in such patients.


    Date de mise en ligne : Mardi 31 janvier 2017
    Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
    Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST)
    Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett’s neoplasia and has advantages over conventional EMR in that it enables en-bloc resection and accurate histopathologic analysis of cancer resection margins. However, its long learning curve and higher adverse event rate have tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett’s neoplasia. The primary endpoint was the en-bloc and R0 resection rate.


    Date de mise en ligne : Mardi 31 janvier 2017
    Takeshi Mizushima, Shunsuke Ohnishi, Hidetaka Hosono, Kenichi Yamahara, Momoko Tsuda, Yuichi Shimizu, Mototsugu Kato, Masahiro Asaka, Naoya Sakamoto
    Oral administration of conditioned medium obtained from mesenchymal stem cell culture prevents subsequent stricture formation after esophageal submucosal dissection in pigs
    Endoscopic submucosal dissection (ESD) for esophageal cancer often causes postoperative stricture when more than three fourths of the circumference of the esophagus is dissected. Mesenchymal stem cells are a valuable cell source in regenerative medicine, and conditioned medium (CM) obtained from mesenchymal stem cells reportedly inhibits inflammation. In this study we evaluated whether CM could prevent esophageal stricture after ESD.


    Date de mise en ligne : Lundi 30 janvier 2017
    Zibing Woodward, Zaida Rodriguez, Janice H. Jou, Kian Keyashian, Yiyi Chen, Charles R. Thomas, Grace H. Elta, Sharlene L. D’Souza
    Gender disparities in gastroenterology fellowship director positions in the United States
    Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims to determine whether this trend exists in 3-year gastroenterology fellowships in the United States and to evaluate for any factors that may affect these differences.


    Date de mise en ligne : Dimanche 29 janvier 2017
    Hiroaki Ikematsu, Taku Sakamoto, Kazutomo Togashi, Naohisa Yoshida, Takashi Hisabe, Shinsuke Kiriyama, Koji Matsuda, Yoshikazu Hayashi, Takahisa Matsuda, Shozo Osera, Kazuhiro Kaneko, Kenichi Utano, Yuji Naito, Hiroshi Ishihara, Masayuki Kato, Kenichi Yoshimura, Hideki Ishikawa, Hironori Yamamoto, Yutaka Saito
    Detectability of colorectal neoplastic lesions using a novel endoscopic system with blue laser imaging: a multicenter randomized controlled trial
    Most studies have not reported an improvement in the detection of adenomas with the use of image-enhanced colonoscopy methods, possibly because of the darkness of the images. To overcome this limitation, a new-generation endoscopic system has been developed. This system has 2 blue-laser imaging (BLI) observation modes. The BLI observation was set to BLI-bright mode to detect lesions. We aimed to evaluate the efficacy of BLI in detecting lesions.


    Date de mise en ligne : Dimanche 29 janvier 2017
    Fabio S. Kawaguti, Adriana R. de Andrade, Stephanie Wodak, Bruno Costa Martins, Fauze Maluf-Filho
    Complete therapeutic response of a large tubulovillous adenoma after chemotherapy
    We describe the case of a woman who underwent urgent right hemicolectomy for obstructive advanced neoplasia. Histopathologic examination revealed poorly differentiated mucinous adenocarcinoma with invasion to the subserosa without vascular or perineural invasion. Seven of 28 resected regional lymph nodes were metastatic (pT3pN2M0). Immunohistochemical study showed microsatellite instability. Adjuvant chemotherapy with oxaliplatin, 5-fluorouracil, leucovorin, and folinic acid was initiated. Colonoscopy revealed a 40-mm sessile polyp in the sigmoid colon with a noninvasive aspect at magnification.


    Date de mise en ligne : Samedi 28 janvier 2017
    Iyad Khamaysi, Yoram Kluger
    The water-lily sign
    A 23-year-old healthy woman presented with epigastric pain. The result of gastroscopy was normal. CT showed 2 adjacent cysts in the lesser sac: a unilocular cyst (A, black arrow) and a septated cyst (A, white arrow). EUS demonstrated 2 cystic lesions: the first cyst was anechoic unilocular, with a thick calcified wall, and the second lesion contained floating laminated membranes within a dense fibrous cystic wall—a finding termed the water-lily sign (B). A hydatid cyst was suspected. Puncture was not performed.


    Date de mise en ligne : Vendredi 27 janvier 2017
    Timo Rath, Christian Bojarski, Markus F. Neurath, Raja Atreya
    Molecular imaging of mucosal α4ÎČ7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn’s disease
    Molecular imaging is based on the use of fluorescent probes with specificity toward defined molecular targets and their visualization by endoscopic devices such as confocal laser endomicroscopy (CLE). Herein, we describe successful molecular imaging of the α4ÎČ7 integrin through CLE in Crohn’s disease (CD). Five patients with CD refractory to anti-tumor necrosis factor (TNF) therapy and with active mucosal inflammation, as shown by high-definition endoscopy, were studied (A). Before induction therapy with the anti-α4ÎČ7 antibody vedolizumab (VDZ), molecular imaging of α4ÎČ7 with fluorescein isothiocyanate (FITC)–labeled VDZ allowed specific identification of α4ÎČ7 expressing mucosal cells with clear discrimination against FITC-IgG1 isotype control in 2 patients with CD responding to subsequent VDZ therapy (B).


    Date de mise en ligne : Vendredi 27 janvier 2017
    Tomonori Yano, Yusuke Yoda, Shogo Nomura, Kayo Toyosaki, Hiromi Hasegawa, Hiroyuki Ono, Masaki Tanaka, Hiroyuki Morimoto, Takahiro Horimatsu, Satoru Nonaka, Kazuhiro Kaneko, Akihiro Sato
    Prospective trial of biodegradable stents for refractory benign esophageal strictures after curative treatment of esophageal cancer
    Biodegradable stents are reportedly effective for refractory benign esophageal strictures; however, little is known about their use in patients with refractory stricture after endoscopic submucosal dissection (ESD) or chemoradiotherapy (CRT) for esophageal cancer. This study aimed to evaluate the effectiveness of biodegradable stents for these patients.


    Date de mise en ligne : Mercredi 25 janvier 2017
    Abdul Hamid El Chafic, David Loren, Ali Siddiqui, Rawad Mounzer, Natalie Cosgrove, Thomas Kowalski
    Comparison of FNA and fine-needle biopsy for EUS-guided sampling of suspected GI stromal tumors
    Subepithelial lesions are found in about 1% of all EGD procedures, and GI stromal tumors are a type of subepithelial lesion commonly encountered. Although the majority of subepithelial lesions are benign, GI stromal tumors have malignant potential, making a definitive diagnosis important. Currently, the criterion standard for the diagnosis of GI stromal tumors is EUS-directed FNA (EUS-FNA). The definitive diagnosis of GI stromal tumors relies on immunohistochemical staining, which depends on enough tissue being submitted to the pathologist.


    Date de mise en ligne : Lundi 09 janvier 2017
    Giovanni D. De Palma, Mariano C. Giglio, Dario Bruzzese, Nicola Gennarelli, Francesco Maione, Saverio Siciliano, Benedetta Manzo, Gianluca Cassese, Gaetano Luglio
    Cap cuff–assisted colonoscopy versus standard colonoscopy for adenoma detection: a randomized back-to-back study
    EndoCuff is a disposable device applied to standard colonoscopes to improve mucosal visualization. Randomized parallel trials have shown that EndoCuff increases the adenoma detection rate (ADR). The primary aim of this study was to compare the ADR between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopies within a randomized back-to-back trial.


    Date de mise en ligne : Lundi 09 janvier 2017
    Loai Mansour, Ferial El-Kalla, Hanan El-Bassat, Sherief Abd-Elsalam, Mohamed El-Bedewy, Abdelrahman Kobtan, Rehab Badawi, Mohamed Elhendawy
    Randomized controlled trial of scleroligation versus band ligation alone for eradication of gastroesophageal varices
    Gastric varices develop in 5% to 33% of patients with portal hypertension. Their most common form is concomitant gastroesophageal varices. Scleroligation (combined sclerotherapy and band ligation) has been used successfully in management of esophageal varices but has not been evaluated previously in the management of gastroesophageal varices. The aim of this work was evaluation of a new scleroligation technique for management of bleeding gastroesophageal varices regarding efficacy, adverse events, variceal recurrence, and survival.


    Date de mise en ligne : Vendredi 06 janvier 2017
    Eelco C. Brand, Vincent K. Dik, Martijn G.H. van Oijen, Peter D. Siersema
    Missed adenomas with behind-folds visualizing colonoscopy technologies compared with standard colonoscopy: a pooled analysis of 3 randomized back-to-back tandem colonoscopy studies
    The Third Eye Retroscope, Full Spectrum Endoscope (FUSE), and EndoRings devices have been shown to reduce overall adenoma miss rates. We evaluated the characteristics of adenomas and patient subgroups for which these behind-folds visualizing technologies mostly reduce adenoma miss rates.


    Date de mise en ligne : Mardi 03 janvier 2017
    Robert J. Huang, Nirav C. Thosani, Monique T. Barakat, Abhishek Choudhary, Alka Mithal, Gurkirpal Singh, Saurabh Sethi, Subhas Banerjee
    Evolution in the utilization of biliary interventions in the United States: results of a nationwide longitudinal study from 1998 to 2013
    Bile duct surgery (BDS), percutaneous transhepatic cholangiography (PTC), and ERCP are alternative interventions used to treat biliary disease. Our aim was to describe trends in ERCP, BDS, and PTC on a nationwide level in the United States.


    Date de mise en ligne : Mardi 03 janvier 2017
    Zhen-Hua Zhao, Liang-Hao Hu, Hong-Bo Ren, An-Jing Zhao, Yang-Yang Qian, Xiao-Tian Sun, Song Su, Shu-Guang Zhu, Jin Yu, Wen-Bin Zou, Xiao-Rong Guo, Lei Wang, Zhao-Shen Li, Zhuan Liao
    Incidence and risk factors for post-ERCP pancreatitis in chronic pancreatitis
    Almost all studies on post-ERCP pancreatitis (PEP) have mainly involved patients with biliary diseases rather than chronic pancreatitis (CP), and the concept that CP seems to be a protective factor associated with PEP has not been studied in detail. The aim of this study was to determine the incidence of PEP in patients with CP at different clinical stages and to identify the predictive and protective factors of PEP in a large cohort.


    Date de mise en ligne : Vendredi 23 décembre 2016
    Vitor Sousa Medeiros, Bruno Costa Martins, Luciano Lenz, Maria Sylvia Ierardi Ribeiro, Gustavo Andrade de Paulo, Marcelo Simas Lima, Adriana Vaz Safatle-Ribeiro, Fabio Shighuehissa Kawaguti, Caterina Pennacchi, Sebastian N. Geiger, Victor R. Bastos, Ulysses Ribeiro-Junior, Rubens A. Sallum, Fauze Maluf-Filho
    Adverse events of self-expandable esophageal metallic stents in patients with long-term survival from advanced malignant disease
    Self-expandable metallic stents are considered the best palliative treatment of dysphagia for patients with advanced esophageal cancer. Adverse events (AEs) are a major concern, especially in patients with better prognosis and longer survival. The present study aimed to evaluate the AEs of patients who survived longer than 6 months with esophageal stents in place.


    Date de mise en ligne : Mercredi 21 décembre 2016
    Umar Hayat, Peter J. Lee, Hamid Ullah, Shashank Sarvepalli, Rocio Lopez, John J. Vargo
    Association of prophylactic endotracheal intubation in critically ill patients with upper GI bleeding and cardiopulmonary unplanned events
    Prophylactic endotracheal intubation (PEI) is often advocated to mitigate the risk of cardiopulmonary adverse events in patients presenting with brisk upper GI bleeding (UGIB). However, the benefit of such a measure remains controversial. Our study aimed to compare the incidence of cardiopulmonary unplanned events between critically ill patients with brisk UGIB who underwent endotracheal intubation versus those who did not.


    Date de mise en ligne : Dimanche 18 décembre 2016
    Satoshi Kinoshita, Toshihiro Nishizawa, Yasutoshi Ochiai, Toshio Uraoka, Teppei Akimoto, Ai Fujimoto, Tadateru Maehata, Osamu Goto, Takanori Kanai, Naohisa Yahagi
    Accuracy of biopsy for the preoperative diagnosis of superficial nonampullary duodenal adenocarcinoma
    Endoscopic biopsy sampling for the diagnosis of duodenal adenocarcinoma is not perfect. We investigated the accuracy of biopsy specimen diagnoses of superficial nonampullary duodenal epithelial tumors (NADETs).


    Date de mise en ligne : Jeudi 15 décembre 2016
    David S. Zimmon, Fred B. Smith, Forrest Manheimer, Cathy Fan, Chantel Njiwaji, Sergei Aksenov, Premtesh Chattoo
    Endoscopic multiple biopsy and rapid diagnosis by in situ fixation and histopathologic processing
    Endoscopic forceps biopsy and fixation are laborious and prolong the procedure and anesthesia. Multiple biopsy overcomes these shortcomings with a single endoscope pass that cuts, like a needle biopsy, up to 25 biopsy samples of uniform size and depth during endoscope withdrawal. Biopsy specimens are collected in acquisition order and stored in a perforated plastic storage chamber within the perforated metal tip. The tip is cut off, immersed in fixative, and sent to pathology. A formatted log identifies each biopsy specimen by site and position.


    Date de mise en ligne : Mardi 06 décembre 2016
    Takemasa Hayashi, Shin-ei Kudo, Hideyuki Miyachi, Tatsuya Sakurai, Tomoyuki Ishigaki, Yusuke Yagawa, Naoya Toyoshima, Yuichi Mori, Masashi Misawa, Toyoki Kudo, Kunihiko Wakamura, Atushi Katagiri, Toshiyuki Baba, Fumio Ishida
    Management and risk factor of stenosis after endoscopic submucosal dissection for colorectal neoplasms
    Although endoscopic submucosal dissection (ESD) enables en bloc removal of large colorectal neoplasms, the incidence of stenosis after ESD and its risk factors have not been well described. This study aimed to determine the risk factors of stenosis and verify the surveillance and treatment of stenosis.


    Date de mise en ligne : Lundi 05 décembre 2016
    Shinichiro Sakata, Antonio H.S. Lee, Ammar O. Kheir, Nicholas J. Tutticci, Sanjeev Naidu, Andrew R.L. Stevenson, David G. Hewett
    Patient acceptance of the optical diagnosis and misdiagnosis of diminutive colorectal polyps
    Optical diagnosis allows for real-time endoscopic assessment of colorectal polyp histology and consists of the resect and discard and diagnose and leave paradigms. This survey assessed patient acceptance of optical diagnosis and their responses to a hypothetical doomsday scenario.


    Date de mise en ligne : Samedi 26 novembre 2016
    Qing-yuan Li, Yan Meng, Yu-yuan Xu, Qiang Zhang, Jian-qun Cai, Hao-xuan Zheng, Hai-tao Qing, Si-lin Huang, Ze-long Han, Ai-min Li, Ying Huang, Ya-li Zhang, Fa-chao Zhi, Rui-jun Cai, Yue Li, Wei Gong, Si-de Liu
    Comparison of endoscopic submucosal tunneling dissection and thoracoscopic enucleation for the treatment of esophageal submucosal tumors
    Endoscopic submucosal tunneling dissection (ESTD) has been proved to be safe and effective for removal of esophageal submucosal tumors (SMTs) and can maintain the mucosal integrity compared with other endoscopic methods. The aim of the study was to estimate the safety and efficacy of ESTD as well as compare its efficacy with thoracoscopic enucleation for esophageal SMTs, which is used increasingly as a minimally invasive approach.


    Date de mise en ligne : Samedi 26 novembre 2016
    Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim, Hyun Kyun Ki
    A randomized controlled trial of prophylactic antibiotics in the prevention of electrocoagulation syndrome after colorectal endoscopic submucosal dissection
    Endoscopic submucosal dissection (ESD) is currently commonly performed, but colorectal ESD has a substantial risk of adverse events, including post-ESD electrocoagulation syndrome (PEECS). We investigated whether the use of prophylactic antibiotics can reduce the occurrence of PEECS.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Michael J. Bartel, Timothy M. Wallace, Rene D. Gomez-Esquivel, Massimo Raimondo, Herbert C. Wolfsen, Timothy A. Woodward, Michael B. Wallace
    Role of EUS in patients with suspected Barrett’s esophagus with high-grade dysplasia or early esophageal adenocarcinoma: impact on endoscopic therapy
    Endoscopic therapy is the standard treatment for high-grade dysplasia and some cases of T1a esophageal adenocarcinoma (EAC), but it is not appropriate for deeply invasive disease. Data on the value of EUS for patient selection for endoscopic or surgical resection are conflicting. We investigated the outcome of esophageal EUS for the staging and treatment selection of patients with treatment-naive, premalignant Barrett’s esophagus (BE) and suspected superficial EAC.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Seung Hun Kang, Yoon Tae Jeen, Jae Hyung Lee, In Kyung Yoo, Jae Min Lee, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Hong Sik Lee, Hoon Jai Chun, Chang Duck Kim
    Comparison of a split-dose bowel preparation with 2 liters of polyethylene glycol plus ascorbic acid and 1 liter of polyethylene glycol plus ascorbic acid and bisacodyl before colonoscopy
    Recently, a low-volume polyethylene glycol formulation containing ascorbic acid (PEG-Asc) has proven as safe and effective as traditional 4-L PEG solutions for colonoscopy preparation. However, currently available aqueous purgative formulations are poorly tolerated. The aim of this study was to compare a split-dose 2-L PEG-Asc formulation and a 1-L PEG-Asc formulation with bisacodyl (10 mg) to determine the quality of bowel cleansing and patient tolerability.


    Date de mise en ligne : Lundi 26 septembre 2016
    Dennis Yang, Roxana M. Coman, Michel Kahaleh, Irving Waxman, Andrew Y. Wang, Amrita Sethi, Ashish R. Shah, Peter V. Draganov
    Endoscopic submucosal dissection for Barrett’s early neoplasia: a multicenter study in the United States
    The role of endoscopic submucosal dissection (ESD) in Barrett’s early neoplasia is not well defined, with most studies originating from Asia and Europe. We aimed to assess the efficacy, safety, and results of ESD in Barrett’s esophagus (BE) with high-grade dysplasia (HGD) and early adenocarcinoma (EAC) across centers in the United States.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Information for readers


    Date de mise en ligne : Jeudi 01 janvier 1970
    In upcoming issues...


    Date de mise en ligne : Jeudi 01 janvier 1970
    ASGE update


    Date de mise en ligne : Jeudi 01 janvier 1970
    Focus on...


    Date de mise en ligne : Jeudi 01 janvier 1970
    Editors


    Date de mise en ligne : Jeudi 01 janvier 1970
    Contents


    Date de mise en ligne : Jeudi 01 janvier 1970
    James Buxbaum, Karthik Ravi, William Ross, Brian Weston, Prasad G. Iyer, Amit Rastogi, Michael B. Wallace
    Continuing Medical Education Exam: August 2017


    Date de mise en ligne : Jeudi 01 janvier 1970
    Sergey V. Kantsevoy
    Stenosis after colorectal endoscopic submucosal dissection: When to expect, how to manage?
    Endoscopic submucosal dissection (ESD) was developed in Japan for the en bloc removal of early gastrointestinal tract lesions.1-3 This technique is rapidly extending around the world, and it is now used for the removal of lesions inside the stomach, esophagus, small bowel, and large bowel.4-6 Although ESD has numerous advantages over traditional piecemeal EMR (eg, en bloc removal allows adequate histologic assessment of lateral and deep margins; ESD is associated with a high rate of curative resection and lower recurrence rates), ESD has a higher rate of immediate (bleeding, perforation) and delayed (bleeding, perforations, stenosis) adverse events compared with EMR.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Lee L. Swanström
    From the belly of the beast

    “
so the beast went to the well and drank, and the noise was in the beast's belly like unto the questing of thirty hounds;
and therewith the beast departed with great noise
 Pellinore, that time king, followed the questing beast.”–Sir Thomas Malory (d. 1471), “Le Morte d'Arthur” (The Death of King Arthur), Book I, Chapter 19“
out of the belly of hell cried I, [and] thou heardest my voice.”–Jonah 2:2


    Date de mise en ligne : Jeudi 01 janvier 1970
    John Baillie
    Fifteen years of ERCP
    I am pleased to write this editorial because it covers the last half (15 years) of my practice at Duke University Medical Center, and beyond. The statistics are pretty accurate. Despite the admission by Huang et al1 that no Veterans' Administration Medical Center data are contained in this review, and there may have been some blurring of indications for in-patient and out-patient care, I agree that this is the direction in which we are all headed. The article by Huang et al1 is a 15-year retrospective of a very large dataset of United States ERCP, both diagnostic and therapeutic.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Jasper L.A. Vleugels, Evelien Dekker
    Blue laser imaging: A promising new kid on the block or another tool to increase detection of low-risk adenomas?
    The efficacy of colorectal cancer screening and surveillance programs relies heavily on the quality of the colonoscopy procedures. If premalignant lesions remain undetected during colonoscopy, the opportunity to prevent the future development of colorectal cancer by removing these lesions is missed. Subsequently, these missed lesions can develop into postcolonoscopy cancers (defined as cancers after a complete colonoscopy).1 In a systematic review published in 2006, the pooled miss rate of premalignant lesions in back-to-back colonoscopies was as high as 22%,2 underlining the necessity to improve polyp detection rates in colonoscopy.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Loren Laine
    Is there a role for combined sclerotherapy and ligation in the endoscopic treatment of gastroesophageal varices?
    Patients with bleeding varices have outcomes that are worse than in patients with other nonmalignant sources of bleeding and engender trepidation in endoscopists. Gastric varices are a less-common source of bleeding than esophageal varices but have more severe bleeding and higher mortality. Many randomized trials inform our treatment of esophageal varices, but far fewer randomized trials are available regarding gastric varices. Furthermore, treatment recommendations vary based on the location of gastric varices.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Luigi Cavanna, Fabio Fornari, Camilla Di Nunzio
    Distance from hospital in clinical practices
    We congratulate Jackson et al1 for the study monitoring the impact of the distance from hospital on the detection of adverse events after outpatient endoscopy.