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Mise à jour le : 30-03-2017




Les derniers abstracts de la revue Gastrointestinal Endoscopy :


    Date de mise en ligne : Mercredi 29 mars 2017
    Enqiang Linghu, Ningli Chai, Chen Du, Bo Ning, Zhiqiang Wang, Yufa Sun, Wei Xu, Huikai Li, Lihua Sun, Wei Zhang, Xu Guo, Xiangdong Wang, Ping Tang, Jia Feng
    A Prospective Study on the Safety and Effectiveness of Using Lauromacrogol for Ablation of Pancreatic Cystic Neoplasms with the Aid of EUS
    With the development of imaging techniques, the detection rate of pancreatic cystic neoplasms (PCNs) has increased. The surgical morbidity and mortality rates of PCNs are quite high. This study is intended to evaluate the safety and effectiveness of a minimally invasive treatment, EUS-guided PCNs ablation with lauromacrogol.


    Date de mise en ligne : Mercredi 29 mars 2017
    Madhav Desai, Andre Sanchez-Yague, Abhishek Choudhary, Asad Pervez, Neil Gupta, Prashanth Vennalaganti, Sreekar Vennelaganti, Alessandro Fugazza, Alessandro Repici, Cesare Hassan, Prateek Sharma
    Impact of Cap-assisted Colonoscopy on Detection of Proximal Colon Adenomas: Systematic Review and Meta-analysis
    Proximal colon adenomas can be missed during routine colonoscopy. Use of a cap or hood on tip of the colonoscope has shown to improve overall adenoma detection with variable rates. However, it has not been systematically evaluated for detection of proximal colon or right-sided adenomas where the cap may have maximum impact on adenoma detection rate (ADR). Our aim was to perform a systematic review and meta-analysis to evaluate the impact of cap colonoscopy (CC) on right-sided adenoma detection rates (r-ADR) compared with standard colonoscopy (SC).


    Date de mise en ligne : Mardi 28 mars 2017
    Carol Durno, C. Richard Boland, Shlomi Cohen, Jason A. Dominitz, Frank M. Giardiello, David A. Johnson, Tonya Kaltenbach, T.R. Levin, David Lieberman, Douglas J. Robertson, Douglas K. Rex
    Recommendations on surveillance and management of biallelic mismatch repair deficiency (BMMRD) syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer
    The US Multi-Society Task Force on Colorectal Cancer, with invited experts, developed a consensus statement and recommendations to assist health care providers with appropriate management of patients with biallelic mismatch repair deficiency (BMMRD) syndrome, also called constitutional mismatch repair deficiency syndrome. This position paper outlines what is known about BMMRD, the unique genetic and clinical aspects of the disease, and reviews the current management approaches to this disorder. This article represents a starting point from which diagnostic and management decisions can undergo rigorous testing for efficacy.


    Date de mise en ligne : Samedi 25 mars 2017
    R. Sanchez-Ocana, I. Penas-Herrero, F. Santos-Santamarta, C. de la Serna-Higuera, M. Perez-Miranda
    EUS-Guided Removal of a Buried Lumen-Apposing Metal Stent Caused by Delayed Inward Migration after Cyst-Gastrostomy


    Date de mise en ligne : Vendredi 24 mars 2017
    Takeshi Ogura, Akira Miyano, Nobu Nishioka, Shinya Fukunishi, Kazuhide Higuchi
    EUS-guided drainage for pancreatic walled-off necrosis by use of a novel large-diameter metal stent


    Date de mise en ligne : Vendredi 24 mars 2017
    Ippei Matsuzaki, Sho Isobe, Ken Hirose, Takahiro Marukawa, Masaya Esaki
    Magnetic anchor-guided endoscopic submucosal dissection for colonic tumor


    Date de mise en ligne : Vendredi 24 mars 2017
    Sujievvan Chandran, Yuto Shimamura, Christopher Teshima
    Novel endoscopic scissors for the treatment of Zenker’s diverticulum


    Date de mise en ligne : Vendredi 24 mars 2017
    Indu Srinivasan, Shou-jiang Tang, James Q. Sones
    Fecal microbial transplantation


    Date de mise en ligne : Mercredi 22 mars 2017
    Yuta Koike
    A rare cause of recurrent acute pancreatitis: duodenum intussusception by a fenestrated duodenal web


    Date de mise en ligne : Mercredi 22 mars 2017
    Mathew Keegan, Rooshdiya Karim, Arthur Kaffes, Payal Saxena
    A welcome diagnosis for painless biliary dilation


    Date de mise en ligne : Mercredi 22 mars 2017
    Sinkeet Rankeeti, Michael Mwachiro, Mark Topazian, Stephen Burgert
    Endoscopic treatment of cervical esophageal transluminal bridge


    Date de mise en ligne : Dimanche 19 mars 2017
    Shani Woolard, Paula Adamson, Emad Qayed
    Esophageal fibrous band causing dysphagia in an HIV+ patient


    Date de mise en ligne : Samedi 18 mars 2017
    Min Min, Yiliang Bi, Yan Liu, Yang Xu
    Extramedullary gastric relapse of acute lymphoblastic leukemia in an adolescent


    Date de mise en ligne : Samedi 18 mars 2017
    Saad A. Khan, Jeremy P. Dwyer, Rhys Vaughan
    Peritoneal carcinomatosis from signet-ring cell adenocarcinoma of the appendix


    Date de mise en ligne : Samedi 18 mars 2017
    Marietta Iacucci, Marco Daperno, Mark Lazarev, Razvan Arsenascu, Gian Eugenio Tontini, Oluseyi Akinola, Xianyong Sean Gui, Vincenzo Villanacci, Martin Goetz, Mark Lowerison, Brendan Cord Lethebe, Maurizio Vecchi, Helmut Neumann, Subrata Ghosh, Raf Bisschops, Ralf Kiesslich
    Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO score (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis
    Endoscopic inflammation and healing are important therapeutic endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual chromoendoscopy (EVC) score that could reflect the full spectrum of mucosal and vascular changes including mucosal healing in UC.


    Date de mise en ligne : Samedi 18 mars 2017
    A. Swager, F. van der Sommen, S.R. Klomp, S. Zinger, S.L. Meijer, E.J. Schoon, J.J. Bergman, P.H.N. de With, W.L. Curvers
    Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy
    Volumetric laser endomicroscopy (VLE) is an advanced imaging system that provides a near-microscopic resolution scan of the esophageal wall layers up to 3 mm deep. VLE has the potential to improve detection of early neoplasia in Barrett’s esophagus (BE). However, interpretation of VLE images is complex due to the large amount of data that needs to be interpreted in real-time. The aim of this study was to investigate the feasibility of a computer algorithm to identify early BE neoplasia on ex vivo VLE images.


    Date de mise en ligne : Samedi 18 mars 2017
    ASGE Technology Committee, Guru Trikudanathan, Rahul Pannala, Manoop S. Bhutani, Joshua Melson, Udayakumar Navaneethan, Mansour A. Parsi, Nirav Thosani, Arvind J. Trindade, Rabindra R. Watson, John T. Maple
    EUS-guided portal vein interventions
    The American Society for Gastrointestinal Endoscopy (ASGE) Technology Committee provides reviews of existing, new, or emerging endoscopic technologies that have an impact on the practice of GI endoscopy. Evidence-based methods are used, with a MEDLINE literature search to identify pertinent clinical studies on the topic and a MAUDE (Food and Drug Administration Center for Devices and Radiological Health) database search to identify the reported adverse events of a given technology. Both are supplemented by accessing the “related articles” feature of PubMed and by scrutinizing pertinent references cited by the identified studies.


    Date de mise en ligne : Lundi 13 mars 2017
    Andrea Oliver Tal, Fabian Finkelmeier, Natalie Filmann, Leena Kylänpää, Marianne Udd, Ilaria Parzanese, Paolo Cantù, Alexander Dechêne, Volker Penndorf, Andreas Schnitzbauer, Mireen Friedrich-Rust, Stefan Zeuzem, Jörg G. Albert
    Multiple Plastic Stents Versus Covered Metal Stent for Treatment of Anastomotic Biliary Strictures after Liver Transplantation: a Prospective, Randomized, Multicenter Trial
    Treatment of anastomotic biliary strictures (ABSs) after orthotopic liver transplantation (OLT) by endoscopic insertion of multiple plastic stents (MPSs) is well-established. The use of covered self-expandable metal stents (cSEMSs) for this indication is less investigated.


    Date de mise en ligne : Vendredi 10 mars 2017
    Douglas G. Adler, Ali A. Siddiqui
    Endoscopic Management of Esophageal Strictures


    Date de mise en ligne : Vendredi 10 mars 2017
    Hae Won Kim, Jie-Hyun Kim, Jun Chul Park, Mi Young Jeon, Yong Chan Lee, Sang Kil Lee, Sung Kwan Shin, Hyun Soo Chung, Sung Hoon Noh, Jong Won Kim, Seung Ho Choi, Jae Jun Park, Young Hoon Youn, Hyojin Park
    Additive endoscopic resection may be sufficient for the patients with positive lateral margin after endoscopic resection of early gastric cancer
    No well-established treatment strategies exist for lateral margin positivity (LM+) alone after endoscopic resection (ER) of early gastric cancer (EGC). Thus, we aimed to clarify treatment strategy of non-curative resection (non-CR) with LM + alone after ER in EGC.


    Date de mise en ligne : Vendredi 10 mars 2017
    Wenjie Liu, Min Wang, Lili Zhao, Min Wang, Xiang Wang, Zhining Fan, Li Liu
    Thermo-sensitive isopentane aerification for mucosal lift during endoscopic resection in animal models (with video)
    Mucosal lift is critical for successful endoscopic treatment. Normal saline solution (NS) is widely used as the submucosal filler, but its short persistency restricts clinical endoscopic submucosal dissection (ESD) procedure. In this study, thermo-sensitive isopentane was introduced for submucosal injection. With a 27.8°C boiling point, liquid isopentane could be easily applied, whereas gasification inflation could provide great support for submucosal lifting at body temperature. The feasibility and efficiency of isopentane were evaluated in this study.


    Date de mise en ligne : Jeudi 09 mars 2017
    Min Min, Pei Deng, Wenhua Zhang, Xiaomin Sun, Yan Liu, Bing Nong
    Comparison of Linked color imaging and white-light colonoscopy for colorectal polyp detection: a multicenter, randomized, crossover trial
    Linked color imaging (LCI) is a recently developed technology that uses a laser endoscopic system to enhance the color separation of red color to depict red and white colors more vividly. The benefits of LCI in colorectal polyp detection remain unknown. The aim of this study was to assess the ability of LCI to increase colorectal polyp detection compared to white-light (WL) endoscopy.


    Date de mise en ligne : Jeudi 09 mars 2017
    Somashekar G. Krishna, William R. Brugge, John M. Dewitt, Pradermchai Kongkam, Bertrand Napoleon, Carlos Robles-Medranda, Damien Tan, Samer El-Dika, Sean McCarthy, Jon Walker, Mary E. Dillhoff, Andrei Manilchuk, Carl Schmidt, Benjamin Swanson, Zarine K. Shah, Phil A. Hart, Darwin L. Conwell
    Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos)
    EUS-guided nCLE characteristics of common types of PCLs have been identified; however surgical histopathology was available in a minority of subjects. We sought to assess the performance characteristics of EUS-nCLE for differentiating mucinous from non-mucinous PCLs in a larger series of subjects with a definitive diagnosis.


    Date de mise en ligne : Jeudi 09 mars 2017
    Rui Huang, Hongwei Cai, Xin Zhao, Xiaoqiang Lu, Min Liu, Wenhao Lv, Zhiguo Liu, Kaichun Wu, Ying Han
    Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma: a propensity score matching analysis
    Esophageal ESD is technically challenging due to the facts of thinner wall and narrow lumen. Tunnel technique was previously proposed. This current retrospective study aimed to evaluate the efficacy of the tunnel technique in ESD of superficial esophageal squamous cell carcinoma (ESCC).


    Date de mise en ligne : Mercredi 08 mars 2017
    Orly Sneh Arbib, Valentina Zemser, Yaara Leibovici Weissman, Rachel Gingold-Belfer, Alex Vilkin, Sapir Eizenstein, Arnon Cohen, Doron Comaneshter, Shochat Tzipora, Yaron Niv, Yeuda Ringel, David Lieberman, Zohar Levi
    Risk of advanced lesions at the first follow-up colonoscopy after polypectomy of diminutive versus small adenomatous polyps of low-grade dysplasia
    The current guidelines for surveillance after polypectomy do not distinguish between diminutive (1–5 mm) and small (6–9 mm) polyps with low-grade dysplasia (LGD). We aimed to evaluate the risk for advanced neoplasia on follow-up colonoscopy.


    Date de mise en ligne : Mercredi 08 mars 2017
    Mi Gang Kim, Se Woo Park, Jae Hyun Kim, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi
    Etomidate Versus Propofol Sedation For Complex Upper Endoscopic Procedures: A Prospective Double-Blinded Randomized Controlled Trial
    Although a growing body of evidence demonstrates that propofol-induced deep sedation can be effective and performed safely, cardiopulmonary adverse events have been frequently observed. Etomidate is a new emerging drug that provides hemodynamic and respiratory stability, even in high-risk patient groups. The objective of this study was to compare safety and efficacy profiles of etomidate and propofol for endoscopic sedation.


    Date de mise en ligne : Mardi 07 mars 2017
    Bing Hu, Bo Sun, Qiang Cai, James Yun Wong Lau, Shuren Ma, Takao Itoi, Jong Ho Moon, Ichiro Yasuda, Xiaofeng Zhang, Hsiu-Po Wang, Shomei Ryozawa, Rungsun Rerknimitr, Wen Li, Hiromu Kutsumi, Sundeep Lakhtakia, Hideyuki Shiomi, Ming Ji, Xun Li, Dongmei Qian, Zhuo Yang, Xiao Zheng
    Asia–Pacific Consensus Guidelines for Endoscopic Management of Benign Biliary Strictures
    Benign biliary strictures (BBSs) are commonly caused by surgical injury, chronic pancreatitis, and inflammatory cholangiopathies. Although advanced imaging tests and tissue acquisition methods have been developed for evaluation of indeterminate biliary strictures, differentiation of BBSs from biliary malignancies remains a challenge to clinicians. The majority of BBSs have good response to nonsurgical treatment and surgical intervention mainly serves as a rescue when nonsurgical approaches fail.


    Date de mise en ligne : Mardi 07 mars 2017
    Dina S. Ahmad, Khalid Sahak, Audrey J. Lazenby, Ishfaq Bhat
    Chronic mesenteric ischemia and gastric ischemia: A bad combination


    Date de mise en ligne : Dimanche 05 mars 2017
    Nicolas Musquer, Merzouka Zidane-Marinnes, Mamoun Dib
    Primary mucosa-associated lymphoid tissue lymphoma of the entire esophagus


    Date de mise en ligne : Mercredi 01 mars 2017
    Markus Dollhopf, Alberto Larghi, Uwe Will, Mihai Rimbaş, Andrea Anderloni, Andres Sanchez-Yague, Anthony Yuen Bun Teoh, Rastislav Kunda
    Eus-Guided Gallbladder Drainage in Patients with Acute Cholecystitis and High Surgical Risk Using an Electrocautery-Enhanced Lumen-Apposing Metal Stent Device
    In high-risk surgical patients, the treatment of choice of acute cholecystitis is percutaneous transhepatic gallbladder drainage (PTGBD). Recently, a novel endoscopic device containing a lumen-apposing metal stent with an electrocautery (ECE-LAMS) on the tip has been developed.


    Date de mise en ligne : Mercredi 01 mars 2017
    Masaya Suenaga, Yoshihiko Sadakari, Jose Alejandro Almario, Michael Borges, Anne-Marie Lennon, Eun-Ji Shin, Marcia Irene Canto, Michael Goggins
    Using an endoscopic distal cap to collect pancreatic fluid from the ampulla (with video)
    Duodenal collections of pancreatic fluid can be used as a source of mutations and other markers of pancreatic ductal neoplasia, but admixing pancreatic juice with duodenal contents lowers the concentrations of mutations. Collecting pancreatic fluid directly from the ampulla could yield a purer sample of pancreatic fluid.


    Date de mise en ligne : Mardi 28 février 2017
    Lorenzo Fuccio, Cesare Hassan, Thierry Ponchon, Daniele Mandolesi, Andrea Farioli, Alessandro Cucchetti, Leonardo Frazzoni, Pradeep Bhandari, Cristina Bellisario, Franco Bazzoli, Alessandro Repici
    Clinical outcomes after endoscopic submucosal dissection for colorectal neoplasia: a systematic review and meta-analysis
    Endoscopic submucosal dissection (ESD) is an endoscopic resection technique for lesions suspicious of superficial malignancy. It is performed using an ESD knife on its own (standard technique) or by the sequential use of a knife and a snare (hybrid technique). The experience with these techniques is different in Asian and non-Asian countries. We performed a systematic review and meta-analysis of available evidences on colorectal ESD.


    Date de mise en ligne : Mardi 28 février 2017
    Laith H. Jamil, Amir Kashani, Neiveen Peter, Simon K. Lo
    Safety and Efficacy of Cap-Assisted Endoscopic Mucosal Resection for Sporadic Nonampullary Duodenal Adenomas
    Eradication of sporadic non-ampullary duodenal adenomas (SNADAs) is essential due to their high rate of malignant transformation. Endoscopic mucosal resection (EMR) techniques are the alternative to the traditional surgical treatments of SNADAs. There are very limited data on the safety and efficacy of cap-assisted EMR (C-EMR) in the treatment of SNADA.


    Date de mise en ligne : Mardi 28 février 2017
    Kyoku Sumimoto, Shinji Tanaka, Kenjiro Shigita, Nana Hayashi, Daiki Hirano, Yuzuru Tamaru, Yuki Ninomiya, Shiro Oka, Koji Arihiro, Fumio Shimamoto, Masaharu Yoshihara, Kazuaki Chayama
    The diagnostic performance of JNET classification for differentiation among noninvasive, superficially invasive, and deeply invasive colorectal neoplasia
    The Japan NBI Expert Team (JNET) classification is the first universal narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors. Considering each type in this classification, the diagnostic ability of Type 2B is the weakest. Generally, clinical behavior is thought to be different in each gross type of colorectal tumor. We evaluated the differences in the diagnostic performance of JNET classification for each gross type (polypoid and superficial) and examined whether the diagnostic performance of Type 2B could improve by subtyping.


    Date de mise en ligne : Jeudi 23 février 2017
    Riccardo Solimando, Alessandro Pezzoli, Viviana Cifalà, Lucio Trevisani, Paolo Pazzi
    Unexpected finding after gastroduodenal artery embolization
    An 87-year-old woman with melena and anemia was admitted to the hospital and underwent urgent GI endoscopy. During the procedure, a large clot adhering to the posterior wall of the duodenal bulb was identified. Its removal with a retrieval net revealed an underlying visible vessel with active oozing (A). After an ineffective attempt to obtain endoscopic hemostasis with epinephrine injection, argon plasma coagulation, and clips, interventional radiology was performed. Selective arteriography of the celiac trunk revealed no extravasation, so blind embolization of the gastroduodenal artery with 3 platinum coils (SPIRALES.018″, coil ∅ 3 mm, coil length 5 cm; Balt Extrusion, Montmorency, France) was carried out (B, continous arrow: coil; dashed arrow: clip).


    Date de mise en ligne : Jeudi 23 février 2017
    Silvia Carrara, Milena Di Leo, Alessandro Repici
    Not only biliary, but also ureteral stones can be detected by EUS


    Date de mise en ligne : Jeudi 23 février 2017
    Rui Gaspar, Pedro Moutinho-Ribeiro, Guilherme Macedo
    Bullous pemphigoid: extensive esophageal involvement
    A 73-year-old woman with a medical history of bullous pemphigoid diagnosed in 2013, who was being treated with prednisolone 20 mg daily, was admitted to our internal medicine department with Escherichia coli urosepsis. She began treatment with ceftriaxone 2 g/day, and the dose of oral prednisolone was lowered to 10 mg/day.


    Date de mise en ligne : Jeudi 23 février 2017
    Ervin Alibegovic, Admir Kurtcehajic, Ahmed Hujdurovic, Adnan Zeco, Dzenita Kurtcehajic
    Acute submucosal hematoma: an adverse event of routine colonoscopy
    A 20-year-old woman underwent diagnostic colonoscopy because of nonspecific lower abdominal pain and problems with elimination (diarrhea and constipation). She had no history of any serious disease or surgery. Her body mass index was 20.2, and the results of physical examination were unremarkable. Her complete blood count was within normal limits, as were nonspecific inflammatory parameters (erythrocyte sedimentation rate, C-reactive protein). The values for biochemical tests including coagulation were within normal ranges.


    Date de mise en ligne : Jeudi 23 février 2017
    Xiaoyu Tang, Yuyong Tan, Deliang Liu
    Angiolipoma: a rare esophageal submucosal tumor
    A 50-year-old man came to our hospital with a 1-month history of chest discomfort. The discomfort increased while he was eating solid food, and he did not describe any retrosternal pain or acid regurgitation. There was no family history of GI cancer. The results of physical examination and laboratory tests were unremarkable. EGD revealed a soft columnar polypoid mass measuring 1.5 × 1.8 cm about 20 cm from the incisors (A), with normal overlying mucosa. EUS showed a homogeneous hyperechoic mass localized in the submucosal layer, without malignant features (B).


    Date de mise en ligne : Mardi 21 février 2017
    Daniela G. Vinsard, Wei-Chung Chen, Victoria Gómez
    Endoscopic band ligation in diverticular bleeding: a stepwise approach for successful treatment
    A 90-year-old man presented to the emergency department with acute painless hematochezia. A previous colonoscopy 2 years earlier confirmed severe diverticulosis in the sigmoid colon with active bleeding from a diverticulum, which was treated with thermal therapy and endoscopic clipping. Digital rectal examination demonstrated gross bright red blood with no evidence of hemorrhoids. Vital signs were negative for hypotension or orthostasis. Laboratory findings included normal hemoglobin and hematocrit: 15.6 g/dL and 44.7%, respectively.


    Date de mise en ligne : Mardi 21 février 2017
    Sindhu Barola, Yen-I Chen, Saowanee Ngamruengphong, Anthony N. Kalloo, Mouen A. Khashab, Vivek Kumbhari
    Technical aspects of endoscopic sleeve gastroplasty
    Of the currently available endoscopic bariatric options in the United States, endoscopic sleeve gastroplasty (ESG) appears to be the most effective and durable. However, it is highly operator dependent. In ESG, the volume of the stomach is reduced by approximately 70% through the creation of a small-diameter sleeve along the lesser curvature of the stomach by use of an endoscopic suturing device (OverStitch, Apollo Endosurgery, Austin, Tex). We present a case that demonstrates important technical aspects of the ESG procedure.


    Date de mise en ligne : Mardi 21 février 2017
    Takao Nishikawa, Shinichiro Okabe, Toshio Tsuyuguchi, Soichiro Kiyono, Shuichi Saito
    Endoscopic recovery of multiple migrated plastic stents during EUS-guided transmural drainage of pancreatic fluid collections
    EUS-guided transmural drainage of pancreatic fluid collections is widely used, and multiple stents and nasocystic drainage are necessary for effective drainage in cases of pancreatic necrosis. Stent migration into the necrotic cyst is a possible adverse event of such procedures. Retrieval of migrated stents by the direct insertion of an endoscope into the cyst can be considered, but there is a high incidence of severe adverse events. We describe a case of multiple plastic stent migration into a pancreatic necrotic cyst, in which the stents were successfully recovered by use of a minimally invasive endoscopic technique.


    Date de mise en ligne : Mardi 21 février 2017
    Yen-I. Chen, Haruhiro Inoue, Michael Ujiki, Peter V. Draganov, Paul Colavita, Francois Mion, John Romanelli, Philip Chiu, Valerio Balassone, Lava Patel, Ali Abbas, Dennis Yang, Christy Dunst, Mathieu Pioche, Sabine Roman, Jérôme Rivory, Thierry Ponchon, David Desilets, Roberta Maselli, Manabu Onimaru, Jun Nakamura, Yoshitaka Hata, Gulara Hajiyeva, Amr Ismail, Saowanee Ngamruengphong, Majidah Bukhari, Yamile Haito Chavez, Vivek Kumbhari, Alessandro Repici, Mouen A. Khashab
    An international multicenter study evaluating the clinical efficacy and safety of per-oral endoscopic myotomy in octogenarians
    Per-oral endoscopic myotomy (POEM) for achalasia is particularly appealing in the elderly due to its minimally invasiveness; however, data in patients age ≥ 80 years are scarce. The aim of this study was to assess the clinical outcome of POEM in octogenarians.


    Date de mise en ligne : Mardi 21 février 2017
    Fariha H. Ramay, Qingping Cui, Bruce D. Greenwald
    Outcomes after liquid nitrogen spray cryotherapy in Barrett's esophagus-associated high-grade dysplasia and intramucosal adenocarcinoma: 5-year follow-up
    Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett’s esophagus (BE)-associated high grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking.


    Date de mise en ligne : Lundi 20 février 2017
    Tejas Kirtane, Bharat Bhandari, Larry D. Scott, Shashideep Singhal
    Overtube-assisted pneumatic dilation for achalasia in Megaesophagus


    Date de mise en ligne : Vendredi 10 février 2017
    Takuto Suzuki, Taro Hara, Yoshiyasu Kitagawa, Hideyuki Takashiro, Rino Nankinzan, Osamu Sugita, Taketo Yamaguchi
    Linked-color imaging improves endoscopic visibility of colorectal nongranular flat lesions
    As a newly developed image-enhanced endoscopy (IEE) technique, linked-color imaging (LCI) provides very bright images with enhanced color tones. With the objective of improving the detection rate of colorectal flat tumor lesions, which are difficult to detect, we examined the usefulness of LCI from the viewpoint of visibility.


    Date de mise en ligne : Mercredi 08 février 2017
    Shishira Bharadwaj, Bo Shen
    Medical, endoscopic, and surgical management of ileal pouch strictures (with video)
    The construction of ileal pouch-anal anastomosis (IPAA) is the procedure of choice for patients with ulcerative colitis or familial adenomatous polyposis, who require colectomy. Furthermore, IPAA has the advantage of preserving the natural route of defecation unlike the Brooke’s ileostomy or continent ileostomies. On the other hand, the natural history of patients with the ileal pouch can be complicated by various surgical-procedure–associated mechanical adverse events as well as inflammatory and functional disorders.


    Date de mise en ligne : Mardi 07 février 2017
    Wouter F.W. Kappelle, Ronald L.A.W. Bleys, Albert J.M. van Wijck, Peter D. Siersema, Frank P. Vleggaar
    EUS-guided celiac ganglia neurolysis: a clinical and human cadaver study (with video)
    There is little evidence that structures targeted during EUS-guided celiac ganglia neurolysis (EUS-CGN) are celiac ganglia and that selective ethanol injection into ganglia is feasible. We aimed to visualize celiac ganglia, confirm that these structures are ganglia, and visualize ethanol spread after EUS-CGN and EUS-guided celiac plexus neurolysis (EUS-CPN).


    Date de mise en ligne : Mardi 07 février 2017
    Ankie Reumkens, Ad A. Masclee, Bjorn Winkens, Cees T. van Deursen, Silvia Sanduleanu, Christine M. Bakker
    Prevalence of hypokalemia before and after bowel preparation for colonoscopy in high-risk patients
    Bowel preparation for colonoscopy should not cause significant shifts in systemic electrolyte concentrations. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal consequences, prompting us to conduct a study to explore the magnitude of and risk factors for hypokalemia associated with bowel preparation. We paid specific attention to higher-risk subgroups, in particular, diuretic users, hospitalized patients, and patients estimated at to be high risk by the gastroenterologist.


    Date de mise en ligne : Mardi 07 février 2017
    Chai Ning-Li, Feng Jia, Guo Yu-Hang, Li Hui-Kai, Ning Bo Wang, Xiangdong Wang, Wang Ying, Wang Yong-hua, Zhai Ya-qi, Linghu En-Qiang
    A preliminary study of single operator cholangioscopy for diagnosing pancreatic cystic lesions
    Advances in imaging technology have improved the annual detection rate of pancreatic cystic lesions, but the preoperative diagnosis of pancreatic cystic lesions remains unclear. Thus, the usefulness of single operator cholangioscopy (SOC) as a diagnostic imaging tool for pancreatic cystic lesions is worth investigating. We performed an intracystic visual examination of pancreatic cystic lesions using SOC to determine the diagnostic value of SOC for pancreatic cystic lesions.


    Date de mise en ligne : Samedi 04 février 2017
    Huiqin He, Chenfei Tan, Jiaguo Wu, Ning Dai, Weiling Hu, Yawen Zhang, Loren Laine, James Scheiman, John J. Kim
    Accuracy of ASGE high-risk criteria in evaluation of patients with suspected common bile duct stones
    ERCP is recommended for patients considered high risk for choledocholithiasis after biochemical testing and abdominal US. Our aim was to determine whether the American Society for Gastrointestinal Endoscopy (ASGE) guidelines accurately select patients for whom the risk of ERCP is justified.


    Date de mise en ligne : Samedi 04 février 2017
    Shozo Osera, Hiroaki Ikematsu, Satoshi Fujii, Keisuke Hori, Yasuhiro Oono, Tomonori Yano, Kazuhiro Kaneko
    Endoscopic treatment outcomes of laterally spreading tumors with a skirt (with video)
    A “skirt” is a slightly elevated flat lesion with wide pits occasionally observed at the margin of laterally spreading tumors (LSTs). However, the endoscopic treatment outcomes of LSTs with skirts have not been clarified. The aim of this study was to evaluate the endoscopic treatment outcomes of LSTs with skirts.


    Date de mise en ligne : Samedi 04 février 2017
    Tannaz Guivatchian, Erika S. Koeppe, Jason R. Baker, Cristina Moisa, Matthew Demerath, Caitlin Foor-Pessin, William D. Chey, Shanti L. Eswaran, Joseph C. Kolars, Stacy B. Menees, Michael Rajala, Michael D. Rice, Rafat Rizk, Joel H. Rubenstein, Pratima Sharma, Andrea Todisco, Elena M. Stoffel
    Family history in colonoscopy patients: feasibility and performance of electronic and paper-based surveys for colorectal cancer risk assessment in the outpatient setting
    Family history is crucial in stratifying patients’ risk for colorectal cancer (CRC). Previous risk assessment tools developed for use in clinic or endoscopy settings have demonstrated suboptimal specificity for identifying patients with hereditary cancer syndromes. Our aim was to test the feasibility and performance of 2 family history surveys (paper and electronic) in individuals presenting for outpatient colonoscopy.


    Date de mise en ligne : Samedi 04 février 2017
    Abdul M. Kouanda, Ma Somsouk, Justin L. Sewell, Lukejohn W. Day
    Urgent colonoscopy in patients with lower GI bleeding: a systematic review and meta-analysis
    Lower GI bleeding (LGIB) is a common cause of morbidity and mortality. Colonoscopy is indicated in all hospitalized patients with LGIB, yet the time frame for performing colonoscopy remains unclear. Prior studies of outcomes in urgent versus elective colonoscopy have yielded conflicting results and were often underpowered. Our study objective was to compare several outcomes between urgent and elective colonoscopy in patients hospitalized for LGIB.


    Date de mise en ligne : Vendredi 03 février 2017
    Hsiang-Chieh Lee, Osman O. Ahsen, Kaicheng Liang, Zhao Wang, Marisa Figueiredo, Michael G. Giacomelli, Benjamin Potsaid, Qin Huang, Hiroshi Mashimo, James G. Fujimoto
    Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus (with video)
    Angiogenesis is associated with neoplastic progression of Barrett’s esophagus (BE). Volumetric optical coherence tomography angiography (OCTA) visualizes subsurface microvasculature without exogenous contrast agents. We investigated the association of OCTA microvascular features with low-grade dysplasia (LGD) and high-grade dysplasia (HGD).


    Date de mise en ligne : Vendredi 03 février 2017
    Árpád Patai, Norbert Solymosi, László Mohácsi, Árpád V. Patai
    Indomethacin and diclofenac in the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis of prospective controlled trials
    Diclofenac and indomethacin are the most studied drugs for preventing post-ERCP pancreatitis (PEP). However, there are no prospective, randomized multicenter trials with a sufficient number of patients for correct evaluation of their efficacy. Our aim was to evaluate all prospective trials published in full text that studied the efficacy of diclofenac or indomethacin and were controlled with placebo or non-treatment for the prevention of PEP in adult patients undergoing ERCP.


    Date de mise en ligne : Mercredi 01 février 2017
    Sunil Dacha, Parit Mekaroonkamol, Lianyong Li, Nikrad Shahnavaz, Sonali Sakaria, Steven Keilin, Field Willingham, Jennifer Christie, Qiang Cai
    Outcomes and quality-of-life assessment after gastric per-oral endoscopic pyloromyotomy (with video)
    Gastric per-oral endoscopic pyloromyotomy (GPOEM) is emerging as a promising option for the treatment of gastroparesis. This study assessed outcomes and quality of life after GPOEM for gastroparesis, performed in an endoscopy unit at a major tertiary referral center.


    Date de mise en ligne : Mercredi 01 février 2017
    A. Swager, A.J. de Groof, S.L. Meijer, B.L. Weusten, W.L. Curvers, Jacques J. Bergman
    Feasibility of laser marking in Barrett’s esophagus with volumetric laser endomicroscopy: first-in-man pilot study
    Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers and has potential to improve detection of neoplasia in Barrett’s esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks (LMs) in different esophageal tissue types on white light endoscopy (WLE) and VLE.


    Date de mise en ligne : Mercredi 01 février 2017
    Alessandro Repici, Roberta Maselli, Silvia Carrara, Andrea Anderloni, Markus Enderle, Cesare Hassan
    Standard needle versus needleless injection modality: animal study on different fluids for submucosal elevation
    Submucosal injection is currently used in GI endoscopy to reduce resection risks and to perform submucosal dissection; it is usually performed via an injection needle or a needleless device. The aim of the study was to compare 2 submucosal injection modalities (needle-assisted vs needleless) by using substances with different viscosities


    Date de mise en ligne : Mardi 31 janvier 2017
    Hamita Sachar, Nipaporn Pichetshote, Kavitha Nandigam, Keta Vaidya, Loren Laine
    Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial
    Current guidelines recommend diphenhydramine in patients undergoing endoscopy who are not adequately sedated with a benzodiazepine and opioid combination. Because this practice has not been adequately assessed, we performed a randomized, double-blind trial comparing diphenhydramine with continued midazolam in such patients.


    Date de mise en ligne : Mardi 31 janvier 2017
    Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
    Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST)
    Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett’s neoplasia and has advantages over conventional EMR in that it enables en-bloc resection and accurate histopathologic analysis of cancer resection margins. However, its long learning curve and higher adverse event rate have tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett’s neoplasia. The primary endpoint was the en-bloc and R0 resection rate.


    Date de mise en ligne : Mardi 31 janvier 2017
    Bo Shen
    Exploring endoscopic therapy for the treatment of Crohn’s disease–related fistula and abscess
    Fistula and abscess represent penetrating disease phenotypes of Crohn’s disease (CD) and can develop in patients with or without prior history of CD-related surgery. While CD fistula and abscess have been traditionally treated with medical and surgical therapy, the role of endoscopic therapy in this particular phenotype of CD is expanding recently, thanks to advanced endoscopic techniques and a better understanding of pathogenesis and natural history of the disease and principle of treatment. The success of endoscopic treatment for inflammatory bowel disease depends on comprehension and appreciation of principles, then techniques, followed by instrument and device.


    Date de mise en ligne : Mardi 31 janvier 2017
    Takeshi Mizushima, Shunsuke Ohnishi, Hidetaka Hosono, Kenichi Yamahara, Momoko Tsuda, Yuichi Shimizu, Mototsugu Kato, Masahiro Asaka, Naoya Sakamoto
    Oral administration of conditioned medium obtained from mesenchymal stem cell culture prevents subsequent stricture formation after esophageal submucosal dissection in pigs
    Endoscopic submucosal dissection (ESD) for esophageal cancer often causes postoperative stricture when more than three fourths of the circumference of the esophagus is dissected. Mesenchymal stem cells are a valuable cell source in regenerative medicine, and conditioned medium (CM) obtained from mesenchymal stem cells reportedly inhibits inflammation. In this study we evaluated whether CM could prevent esophageal stricture after ESD.


    Date de mise en ligne : Lundi 30 janvier 2017
    Joseph C. Anderson, Lynn F. Butterly, Julia E. Weiss, Christina M. Robinson
    Providing data for serrated polyp detection rate benchmarks: an analysis of the New Hampshire Colonoscopy Registry
    Similar to achieving adenoma detection rate (ADR) benchmarks to prevent colorectal cancer (CRC), achieving adequate serrated polyp detection rates (SDRs) may be essential to the prevention of CRC associated with the serrated pathway. Previous studies have been based on data from high-volume endoscopists at single academic centers. Based on a hypothesis that ADR is correlated with SDR, we stratified a large, diverse group of endoscopists (n = 77 practicing at 28 centers) into high performers and low performers, based on ADR, to provide data for corresponding target SDR benchmarks.


    Date de mise en ligne : Lundi 30 janvier 2017
    Zibing Woodward, Zaida Rodriguez, Janice H. Jou, Kian Keyashian, Yiyi Chen, Charles R. Thomas, Grace H. Elta, Sharlene L. D’Souza
    Gender disparities in gastroenterology fellowship director positions in the United States
    Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims to determine whether this trend exists in 3-year gastroenterology fellowships in the United States and to evaluate for any factors that may affect these differences.


    Date de mise en ligne : Dimanche 29 janvier 2017
    Hiroaki Ikematsu, Taku Sakamoto, Kazutomo Togashi, Naohisa Yoshida, Takashi Hisabe, Shinsuke Kiriyama, Koji Matsuda, Yoshikazu Hayashi, Takahisa Matsuda, Shozo Osera, Kazuhiro Kaneko, Kenichi Utano, Yuji Naito, Hiroshi Ishihara, Masayuki Kato, Kenichi Yoshimura, Hideki Ishikawa, Hironori Yamamoto, Yutaka Saito
    Detectability of colorectal neoplastic lesions using a novel endoscopic system with blue laser imaging: a multicenter randomized controlled trial
    Most studies have not reported an improvement in the detection of adenomas with the use of image-enhanced colonoscopy methods, possibly because of the darkness of the images. To overcome this limitation, a new-generation endoscopic system has been developed. This system has 2 blue-laser imaging (BLI) observation modes. The BLI observation was set to BLI-bright mode to detect lesions. We aimed to evaluate the efficacy of BLI in detecting lesions.


    Date de mise en ligne : Dimanche 29 janvier 2017
    Fabio S. Kawaguti, Adriana R. de Andrade, Stephanie Wodak, Bruno Costa Martins, Fauze Maluf-Filho
    Complete therapeutic response of a large tubulovillous adenoma after chemotherapy
    We describe the case of a woman who underwent urgent right hemicolectomy for obstructive advanced neoplasia. Histopathologic examination revealed poorly differentiated mucinous adenocarcinoma with invasion to the subserosa without vascular or perineural invasion. Seven of 28 resected regional lymph nodes were metastatic (pT3pN2M0). Immunohistochemical study showed microsatellite instability. Adjuvant chemotherapy with oxaliplatin, 5-fluorouracil, leucovorin, and folinic acid was initiated. Colonoscopy revealed a 40-mm sessile polyp in the sigmoid colon with a noninvasive aspect at magnification.


    Date de mise en ligne : Samedi 28 janvier 2017
    Iyad Khamaysi, Yoram Kluger
    The water-lily sign
    A 23-year-old healthy woman presented with epigastric pain. The result of gastroscopy was normal. CT showed 2 adjacent cysts in the lesser sac: a unilocular cyst (A, black arrow) and a septated cyst (A, white arrow). EUS demonstrated 2 cystic lesions: the first cyst was anechoic unilocular, with a thick calcified wall, and the second lesion contained floating laminated membranes within a dense fibrous cystic wall—a finding termed the water-lily sign (B). A hydatid cyst was suspected. Puncture was not performed.


    Date de mise en ligne : Vendredi 27 janvier 2017
    Eun Jung Jun, Jung-Hoon Park, Jiaywei Tsauo, Su-Geun Yang, Dae-Kee Kim, Kun Yung Kim, Min Tae Kim, Sung-Hwan Yoon, Young Je Lim, Ho-Young Song
    EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus
    Self-expanding metallic stent (SEMS) placement is a well-established method for treating malignant esophageal strictures; however, this procedure has not gained widespread acceptance for treating benign esophageal strictures because of granulation tissue formation. The aim of the present study was to investigate whether EW-7197, a novel per-oral transforming growth factor-β type I receptor kinase inhibitor, suppressed granulation tissue formation after SEMS placement in the rat esophagus.


    Date de mise en ligne : Vendredi 27 janvier 2017
    Timo Rath, Christian Bojarski, Markus F. Neurath, Raja Atreya
    Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn’s disease
    Molecular imaging is based on the use of fluorescent probes with specificity toward defined molecular targets and their visualization by endoscopic devices such as confocal laser endomicroscopy (CLE). Herein, we describe successful molecular imaging of the α4β7 integrin through CLE in Crohn’s disease (CD). Five patients with CD refractory to anti-tumor necrosis factor (TNF) therapy and with active mucosal inflammation, as shown by high-definition endoscopy, were studied (A). Before induction therapy with the anti-α4β7 antibody vedolizumab (VDZ), molecular imaging of α4β7 with fluorescein isothiocyanate (FITC)–labeled VDZ allowed specific identification of α4β7 expressing mucosal cells with clear discrimination against FITC-IgG1 isotype control in 2 patients with CD responding to subsequent VDZ therapy (B).


    Date de mise en ligne : Vendredi 27 janvier 2017
    Tomonori Yano, Yusuke Yoda, Shogo Nomura, Kayo Toyosaki, Hiromi Hasegawa, Hiroyuki Ono, Masaki Tanaka, Hiroyuki Morimoto, Takahiro Horimatsu, Satoru Nonaka, Kazuhiro Kaneko, Akihiro Sato
    Prospective trial of biodegradable stents for refractory benign esophageal strictures after curative treatment of esophageal cancer
    Biodegradable stents are reportedly effective for refractory benign esophageal strictures; however, little is known about their use in patients with refractory stricture after endoscopic submucosal dissection (ESD) or chemoradiotherapy (CRT) for esophageal cancer. This study aimed to evaluate the effectiveness of biodegradable stents for these patients.


    Date de mise en ligne : Mercredi 25 janvier 2017
    Abdul Hamid El Chafic, David Loren, Ali Siddiqui, Rawad Mounzer, Natalie Cosgrove, Thomas Kowalski
    Comparison of FNA and fine-needle biopsy for EUS-guided sampling of suspected GI stromal tumors
    Subepithelial lesions are found in about 1% of all EGD procedures, and GI stromal tumors are a type of subepithelial lesion commonly encountered. Although the majority of subepithelial lesions are benign, GI stromal tumors have malignant potential, making a definitive diagnosis important. Currently, the criterion standard for the diagnosis of GI stromal tumors is EUS-directed FNA (EUS-FNA). The definitive diagnosis of GI stromal tumors relies on immunohistochemical staining, which depends on enough tissue being submitted to the pathologist.


    Date de mise en ligne : Mercredi 25 janvier 2017
    Guilherme Piovezani Ramos, Korosh Sharain, Karthik Ravi
    Juvenile polyposis and hereditary hemorrhagic telangiectasia overlap syndrome
    A 67-year-old woman with a history of ulcerative colitis, status postproctocolectomy with end ileostomy, presented with persistent iron-deficiency anemia. Her family history was significant for a daughter with gastric cancer and intracranial aneurysms. Physical examination showed multiple cherry angiomas and superficial telangiectasias on her upper back. An extended upper endoscopy revealed several large nonbleeding angioectasias throughout the stomach and the duodenum (A). Additionally, multiple 2-mm to 12-mm pedunculated and sessile polyps with no bleeding were found throughout the duodenum (B).


    Date de mise en ligne : Mercredi 18 janvier 2017
    Swathi Eluri, Nicholas J. Shaheen
    Barrett's esophagus: diagnosis and management
    Barrett’s esophagus (BE) is characterized by a change of the normal stratified squamous epithelium lining the esophagus to a metaplastic columnar epithelium with goblet cells. The prevalence of BE is estimated to be 1.5% in the general population1,2 and as high as 15% in those with GERD.3,4 Other risk factors associated with BE are older age, male sex, smoking, central obesity, and white ethnicity.5-10 There also appears to be an increased genetic predisposition among those with first-degree relatives with BE.


    Date de mise en ligne : Lundi 09 janvier 2017
    Giovanni D. De Palma, Mariano C. Giglio, Dario Bruzzese, Nicola Gennarelli, Francesco Maione, Saverio Siciliano, Benedetta Manzo, Gianluca Cassese, Gaetano Luglio
    Cap cuff–assisted colonoscopy versus standard colonoscopy for adenoma detection: a randomized back-to-back study
    EndoCuff is a disposable device applied to standard colonoscopes to improve mucosal visualization. Randomized parallel trials have shown that EndoCuff increases the adenoma detection rate (ADR). The primary aim of this study was to compare the ADR between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopies within a randomized back-to-back trial.


    Date de mise en ligne : Lundi 09 janvier 2017
    Loai Mansour, Ferial El-Kalla, Hanan El-Bassat, Sherief Abd-Elsalam, Mohamed El-Bedewy, Abdelrahman Kobtan, Rehab Badawi, Mohamed Elhendawy
    Randomized controlled trial of scleroligation versus band ligation alone for eradication of gastroesophageal varices
    Gastric varices develop in 5% to 33% of patients with portal hypertension. Their most common form is concomitant gastroesophageal varices. Scleroligation (combined sclerotherapy and band ligation) has been used successfully in management of esophageal varices but has not been evaluated previously in the management of gastroesophageal varices. The aim of this work was evaluation of a new scleroligation technique for management of bleeding gastroesophageal varices regarding efficacy, adverse events, variceal recurrence, and survival.


    Date de mise en ligne : Vendredi 06 janvier 2017
    Eelco C. Brand, Vincent K. Dik, Martijn G.H. van Oijen, Peter D. Siersema
    Missed adenomas with behind-folds visualizing colonoscopy technologies compared with standard colonoscopy: a pooled analysis of 3 randomized back-to-back tandem colonoscopy studies
    The Third Eye Retroscope, Full Spectrum Endoscope (FUSE), and EndoRings devices have been shown to reduce overall adenoma miss rates. We evaluated the characteristics of adenomas and patient subgroups for which these behind-folds visualizing technologies mostly reduce adenoma miss rates.


    Date de mise en ligne : Vendredi 06 janvier 2017
    Mona Rezapour, Chidi Amadi, Lauren Gerson
    Retention associated with video capsule endoscopy: systematic review and meta-analysis
    Video capsule endoscopy (VCE) has become a major diagnostic tool for small-bowel evaluation. However, retention of the video capsule endoscope remains a major concern.


    Date de mise en ligne : Mercredi 04 janvier 2017
    Reem Z. Sharaiha, Muhammad Ali Khan, Faisal Kamal, Amy Tyberg, Claudio R. Tombazzi, Bilal Ali, Claudio Tombazzi, Michel Kahaleh
    Efficacy and safety of EUS-guided biliary drainage in comparison with percutaneous biliary drainage when ERCP fails: a systematic review and meta-analysis
    EUS-guided biliary drainage (EUS-BD) is increasingly used as an alternate therapeutic modality to percutaneous transhepatic biliary drainage (PTBD) for biliary obstruction in patients who fail ERCP. We conducted a systematic review and meta-analysis to compare the efficacy and safety of these 2 procedures.


    Date de mise en ligne : Mardi 03 janvier 2017
    Robert J. Huang, Nirav C. Thosani, Monique T. Barakat, Abhishek Choudhary, Alka Mithal, Gurkirpal Singh, Saurabh Sethi, Subhas Banerjee
    Evolution in the utilization of biliary interventions in the United States: results of a nationwide longitudinal study from 1998 to 2013
    Bile duct surgery (BDS), percutaneous transhepatic cholangiography (PTC), and ERCP are alternative interventions used to treat biliary disease. Our aim was to describe trends in ERCP, BDS, and PTC on a nationwide level in the United States.


    Date de mise en ligne : Mardi 03 janvier 2017
    Zhen-Hua Zhao, Liang-Hao Hu, Hong-Bo Ren, An-Jing Zhao, Yang-Yang Qian, Xiao-Tian Sun, Song Su, Shu-Guang Zhu, Jin Yu, Wen-Bin Zou, Xiao-Rong Guo, Lei Wang, Zhao-Shen Li, Zhuan Liao
    Incidence and risk factors for post-ERCP pancreatitis in chronic pancreatitis
    Almost all studies on post-ERCP pancreatitis (PEP) have mainly involved patients with biliary diseases rather than chronic pancreatitis (CP), and the concept that CP seems to be a protective factor associated with PEP has not been studied in detail. The aim of this study was to determine the incidence of PEP in patients with CP at different clinical stages and to identify the predictive and protective factors of PEP in a large cohort.


    Date de mise en ligne : Vendredi 23 décembre 2016
    Vitor Sousa Medeiros, Bruno Costa Martins, Luciano Lenz, Maria Sylvia Ierardi Ribeiro, Gustavo Andrade de Paulo, Marcelo Simas Lima, Adriana Vaz Safatle-Ribeiro, Fabio Shighuehissa Kawaguti, Caterina Pennacchi, Sebastian N. Geiger, Victor R. Bastos, Ulysses Ribeiro-Junior, Rubens A. Sallum, Fauze Maluf-Filho
    Adverse events of self-expandable esophageal metallic stents in patients with long-term survival from advanced malignant disease
    Self-expandable metallic stents are considered the best palliative treatment of dysphagia for patients with advanced esophageal cancer. Adverse events (AEs) are a major concern, especially in patients with better prognosis and longer survival. The present study aimed to evaluate the AEs of patients who survived longer than 6 months with esophageal stents in place.


    Date de mise en ligne : Vendredi 23 décembre 2016
    Jasper L.A. Vleugels, Yark Hazewinkel, Paul Fockens, Evelien Dekker
    Natural history of diminutive and small colorectal polyps: a systematic literature review
    Diminutive (1-5 mm) and small (6-9 mm) polyps comprise 90% of detected lesions during colonoscopy and rarely contain advanced histology or colorectal cancer (CRC). Routine removal of these lesions results in a significant burden to colonoscopy programs. At the same time, the risk for progression of these polyps to CRC is unclear. We performed a systematic review to explore the natural history of diminutive and small colorectal polyps.


    Date de mise en ligne : Jeudi 22 décembre 2016
    Lyndon V. Hernandez
    How robust is our peer-review system? A review of emerging models
    Peer review is an enduring institution for ensuring quality and integrity of research. Every year dedicated editors and reviewers carefully sift through thousands of manuscripts and videos from behind the scenes. This scholarly cycle of sorting, correcting, purging, and publishing is almost routine and was taken for granted, until something unthinkable happened that alarmed the scientific world. A submitting author systematically recommended names of potential reviewers to scientific journals and then hacked into their electronic editorial systems to provide fictitious e-mail addresses, enabling him to create favorable reviews that led to his manuscripts being accepted and published.


    Date de mise en ligne : Jeudi 22 décembre 2016
    Rintaro Hashimoto, Dai Hirasawa, Akimichi Chonan, Hajime Yamaoka, Masato Nakahori
    “Small white sign” in Barrett’s esophageal cancer under the squamous epithelium
    A 74-year-old man visited our hospital because of epigastric discomfort. EGD revealed a subtle reddish, flat, elevated lesion 40 mm in diameter in the right anterior wall of the esophagogastric junction (A). Examination of a biopsy specimen revealed a well-differentiated adenocarcinoma. Irregular meshlike vessels were observed within the lesion using magnifying narrow-band imaging (NBI) endoscopy (B). Acetic acid spraying revealed multiple small white spots on the neighboring squamous epithelium (C, arrows).


    Date de mise en ligne : Jeudi 22 décembre 2016
    Bryan Rea, Dale Frank
    An uncommon manifestation of acute leukemia
    A 49-year-old man with no significant medical history presented with melena and persistent hematochezia. Colonoscopy revealed a 2.0-cm erythematous polyp in the distal sigmoid colon (A), which was removed by hot snare polypectomy. Hematoxylin and eosin–stained sections showed adenomatous colonic epithelium. The lamina propria was expanded by an infiltrate of large mitotically active cells with irregular nuclei, fine chromatin, and prominent nucleoli (B). Immunohistochemical stains confirmed that they were CD4+ CD15+ CD68+ (C) CD117+ lysozyme+ MPO+ (D) CD34− blasts.


    Date de mise en ligne : Mercredi 21 décembre 2016
    Yuga Komaki, Fukiko Komaki, Dejan Micic, Akio Ido, Atsushi Sakuraba
    Risk of colorectal cancer in chronic liver diseases: a systematic review and meta-analysis
    The risk of colorectal cancer (CRC) in various chronic liver diseases compared with the general population remains unclear. We performed a systematic review and meta-analysis to assess the risk of CRC in patients with chronic liver diseases before and after liver transplantation.


    Date de mise en ligne : Mercredi 21 décembre 2016
    Umar Hayat, Peter J. Lee, Hamid Ullah, Shashank Sarvepalli, Rocio Lopez, John J. Vargo
    Association of prophylactic endotracheal intubation in critically ill patients with upper GI bleeding and cardiopulmonary unplanned events
    Prophylactic endotracheal intubation (PEI) is often advocated to mitigate the risk of cardiopulmonary adverse events in patients presenting with brisk upper GI bleeding (UGIB). However, the benefit of such a measure remains controversial. Our study aimed to compare the incidence of cardiopulmonary unplanned events between critically ill patients with brisk UGIB who underwent endotracheal intubation versus those who did not.


    Date de mise en ligne : Dimanche 18 décembre 2016
    Satoshi Kinoshita, Toshihiro Nishizawa, Yasutoshi Ochiai, Toshio Uraoka, Teppei Akimoto, Ai Fujimoto, Tadateru Maehata, Osamu Goto, Takanori Kanai, Naohisa Yahagi
    Accuracy of biopsy for the preoperative diagnosis of superficial nonampullary duodenal adenocarcinoma
    Endoscopic biopsy sampling for the diagnosis of duodenal adenocarcinoma is not perfect. We investigated the accuracy of biopsy specimen diagnoses of superficial nonampullary duodenal epithelial tumors (NADETs).


    Date de mise en ligne : Jeudi 15 décembre 2016
    David S. Zimmon, Fred B. Smith, Forrest Manheimer, Cathy Fan, Chantel Njiwaji, Sergei Aksenov, Premtesh Chattoo
    Endoscopic multiple biopsy and rapid diagnosis by in situ fixation and histopathologic processing
    Endoscopic forceps biopsy and fixation are laborious and prolong the procedure and anesthesia. Multiple biopsy overcomes these shortcomings with a single endoscope pass that cuts, like a needle biopsy, up to 25 biopsy samples of uniform size and depth during endoscope withdrawal. Biopsy specimens are collected in acquisition order and stored in a perforated plastic storage chamber within the perforated metal tip. The tip is cut off, immersed in fixative, and sent to pathology. A formatted log identifies each biopsy specimen by site and position.


    Date de mise en ligne : Mercredi 14 décembre 2016
    Yu-Hsi Hsieh, Chih-Wei Tseng, Chi-Tan Hu, Malcolm Koo, Felix W. Leung
    Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation
    Adenoma detection rate (ADR), defined as the proportion of patients with at least one adenoma of any size, is a quality indicator. We tested the hypothesis that water exchange (WE) improves ADR but water immersion (WI) has no adverse effect on ADR compared with air insufflation (AI).


    Date de mise en ligne : Vendredi 09 décembre 2016
    K. Nadine Phoa, Wilda D. Rosmolen, Bas L.A.M. Weusten, Raf Bisschops, Erik J. Schoon, Shefali Das, Krish Ragunath, G. Fullarton, Massimiliano DiPietro, Narayanasamy Ravi, Jan G.P. Tijssen, Marcel G.W. Dijkgraaf, Jacques J.G.H.M. Bergman, SURF investigators
    The cost-effectiveness of radiofrequency ablation for Barrett's esophagus with low-grade dysplasia: results from a randomized controlled trial (SURF trial)
    The Surveillance versus Radiofrequency Ablation (SURF) trial randomized 136 patients with Barrett's esophagus (BE) containing low-grade dysplasia (LGD), to receive radiofrequency ablation (ablation, n = 68) or endoscopic surveillance (control, n = 68). Ablation reduced the risk of neoplastic progression to high-grade dysplasia and esophageal adenocarcinoma (EAC) by 25% over 3 years (1.5% for ablation vs 26.5% for control). We performed a cost-effectiveness analysis from a provider perspective alongside this trial.


    Date de mise en ligne : Jeudi 08 décembre 2016
    Harathi Yandrapu, Madhav Desai, Sameer Siddique, Prashanth Vennalganti, Sreekar Vennalaganti, Sravanthi Parasa, Tarun Rai, Vijay Kanakadandi, Ajay Bansal, Mohammad Titi, Alessandro Repici, Matthew L. Bechtold, Prateek Sharma, Abhishek Choudhary
    Normal saline solution versus other viscous solutions for submucosal injection during endoscopic mucosal resection: a systematic review and meta-analysis
    EMR is being increasingly practiced for the removal of large colorectal polyps. A variety of solutions such as normal saline solution (NS) and other viscous and hypertonic solutions (VS) have been used as submucosal injections for EMR. A systematic review and meta-analysis is presented comparing the efficacy and adverse events of EMR performed using NS versus VS.


    Date de mise en ligne : Mardi 06 décembre 2016
    Takemasa Hayashi, Shin-ei Kudo, Hideyuki Miyachi, Tatsuya Sakurai, Tomoyuki Ishigaki, Yusuke Yagawa, Naoya Toyoshima, Yuichi Mori, Masashi Misawa, Toyoki Kudo, Kunihiko Wakamura, Atushi Katagiri, Toshiyuki Baba, Fumio Ishida
    Management and risk factor of stenosis after endoscopic submucosal dissection for colorectal neoplasms
    Although endoscopic submucosal dissection (ESD) enables en bloc removal of large colorectal neoplasms, the incidence of stenosis after ESD and its risk factors have not been well described. This study aimed to determine the risk factors of stenosis and verify the surveillance and treatment of stenosis.


    Date de mise en ligne : Lundi 05 décembre 2016
    Shinichiro Sakata, Antonio H.S. Lee, Ammar O. Kheir, Nicholas J. Tutticci, Sanjeev Naidu, Andrew R.L. Stevenson, David G. Hewett
    Patient acceptance of the optical diagnosis and misdiagnosis of diminutive colorectal polyps
    Optical diagnosis allows for real-time endoscopic assessment of colorectal polyp histology and consists of the resect and discard and diagnose and leave paradigms. This survey assessed patient acceptance of optical diagnosis and their responses to a hypothetical doomsday scenario.


    Date de mise en ligne : Lundi 05 décembre 2016
    Sheila Kumar, Nirav Thosani, Uri Ladabaum, Shai Friedland, Ann M. Chen, Rajan Kochar, Subhas Banerjee
    Adenoma miss rates associated with a 3-minute versus 6-minute colonoscopy withdrawal time: a prospective, randomized trial
    The 6-minute withdrawal time for colonoscopy, widely considered the standard of care, is controversial. The skill and technique of endoscopists may be as important as, or more important than, withdrawal time for adenoma detection. It is unclear whether a shorter withdrawal time with good technique yields an acceptable lesion detection rate. Our objective was to evaluate a 3-minute versus a 6-minute withdrawal time by using segmental tandem colonoscopy.


    Date de mise en ligne : Lundi 28 novembre 2016
    Shuntaro Mukai, Takayoshi Tsuchiya, Takao Itoi, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Yuichi Nagakawa, Kazuhiko Kasuya, Masaaki Shimatani, Atsushi Sofuni
    Prospective evaluation of a new biflanged metal stent for the treatment of pancreatic fluid collections (with videos)
    EUS-guided transluminal drainage (EUS-TD) and sequential direct endoscopic necrosectomy (DEN) for pancreatic fluid collections (PFCs) by using a dedicated biflanged metal stent (BFMS) has been reported as a useful alternative to using plastic stents or a conventional metal stent. However, current dedicated BFMSs have limitations. Recently, a new BFMS with solidly constructed biflanges and various stent lengths matched to the PFC condition has been developed. Herein, we prospectively evaluated this new BFMS for the treatment of PFCs.


    Date de mise en ligne : Samedi 26 novembre 2016
    Arvind J. Trindade, Sumant Inamdar, Michael S. Smith, Kenneth J. Chang, Cadman L. Leggett, Charles J. Lightdale, Douglas K. Pleskow, Divyesh V. Sejpal, Guillermo J. Tearney, Rebecca M. Thomas, Michael B. Wallace
    Volumetric laser endomicroscopy in Barrett’s esophagus: interobserver agreement for interpretation of Barrett’s esophagus and associated neoplasia among high-frequency users
    Targeting neoplasia in Barrett’s esophagus (BE) is challenging. Volumetric laser endomicroscopy (VLE) is a new imaging technique that allows for real time cross-sectional microstructure imaging that can detect BE neoplasia. The interobserver agreement among users in practice is unknown.


    Date de mise en ligne : Samedi 26 novembre 2016
    Qing-yuan Li, Yan Meng, Yu-yuan Xu, Qiang Zhang, Jian-qun Cai, Hao-xuan Zheng, Hai-tao Qing, Si-lin Huang, Ze-long Han, Ai-min Li, Ying Huang, Ya-li Zhang, Fa-chao Zhi, Rui-jun Cai, Yue Li, Wei Gong, Si-de Liu
    Comparison of endoscopic submucosal tunneling dissection and thoracoscopic enucleation for the treatment of esophageal submucosal tumors
    Endoscopic submucosal tunneling dissection (ESTD) has been proved to be safe and effective for removal of esophageal submucosal tumors (SMTs) and can maintain the mucosal integrity compared with other endoscopic methods. The aim of the study was to estimate the safety and efficacy of ESTD as well as compare its efficacy with thoracoscopic enucleation for esophageal SMTs, which is used increasingly as a minimally invasive approach.


    Date de mise en ligne : Samedi 26 novembre 2016
    Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim, Hyun Kyun Ki
    A randomized controlled trial of prophylactic antibiotics in the prevention of electrocoagulation syndrome after colorectal endoscopic submucosal dissection
    Endoscopic submucosal dissection (ESD) is currently commonly performed, but colorectal ESD has a substantial risk of adverse events, including post-ESD electrocoagulation syndrome (PEECS). We investigated whether the use of prophylactic antibiotics can reduce the occurrence of PEECS.


    Date de mise en ligne : Vendredi 25 novembre 2016
    Dep K. Huynh, Leanne Toscano, Vinh-An Phan, Tsai-Wing Ow, Mark Schoeman, Nam Q. Nguyen
    Ultrathin disposable gastroscope for screening and surveillance of gastroesophageal varices in patients with liver cirrhosis: a prospective comparative study
    This study aims to evaluate the role of unsedated, ultrathin disposable gastroscopy (TDG) against conventional gastroscopy (CG) in the screening and surveillance of gastroesophageal varices (GEVs) in patients with liver cirrhosis.


    Date de mise en ligne : Jeudi 24 novembre 2016
    John M. DeWitt, S. Krishna Murthy, Ramesh Ardhanari, G. Aaron DuVall, Grzegorz Wallner, Paul Litka, Claire Daugherty, Kirk Fowers
    EUS-guided paclitaxel injection as an adjunctive therapy to systemic chemotherapy and concurrent external beam radiation before surgery for localized or locoregional esophageal cancer: a multicenter prospective randomized trial
    OncoGel (Protherics Salt Lake City, Inc, Salt Lake City, UT) is paclitaxel (PTX) formulated in a thermosensitive, biodegradable copolymer for focused cytotoxicity and radiosensitization. A phase 2a study suggested that EUS-guided PTX injection into esophageal tumors subsequently receiving radiotherapy was safe.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Yosuke Toya, Masaki Endo, Shotaro Nakamura, Risaburo Akasaka, Takashi Kosaka, Shunichi Yanai, Keisuke Kawasaki, Keisuke Koeda, Tamotsu Sugai, Takayuki Matsumoto
    Clinical outcomes of non-curative endoscopic submucosal dissection with negative resected margins for gastric cancer
    There has been little information about the long-term outcomes of patients with early gastric cancer (EGC) treated by non-curative endoscopic submucosal dissection (ESD) with negative resected margins (R0 resection). We aimed to compare the clinical outcomes of non-curative ESD with R0 resection between patients who underwent additional gastrectomy and those who did not.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Su Young Kim, Jun-Won Chung, Dong Kyun Park, Kwang An Kwon, Kyoung Oh Kim, Yoon Jae Kim, Jung Ho Kim
    Comparison of carbon dioxide and air insufflation during consecutive EGD and colonoscopy in moderate-sedation patients: a prospective, double-blind, randomized controlled trial
    Endoscopy is performed with air insufflation and is usually associated with abdominal pain. It is well recognized that carbon dioxide (CO2) is absorbed more quickly into the body than air; however, to date, few studies have investigated the use of CO2 insufflation during consecutive EGD and colonoscopy (CEC). Thus, this study evaluated the efficacy of CO2 insufflation compared with air insufflation in CEC.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Jennifer Nayor, John R. Saltzman, Emily J. Campbell, Molly L. Perencevich, Kunal Jajoo, James M. Richter
    Impact of physician compliance with colonoscopy surveillance guidelines on interval colorectal cancer
    Interval colorectal cancer (iCRC) incidence is the criterion standard benchmark for measuring the effectiveness of colonoscopy. Colonoscopy surveillance guidelines are designed to minimize iCRC cases. Our aims were to describe characteristics of iCRC patients and to assess whether development of iCRC is related to colonoscopy surveillance guideline intervals.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Michael J. Bartel, Timothy M. Wallace, Rene D. Gomez-Esquivel, Massimo Raimondo, Herbert C. Wolfsen, Timothy A. Woodward, Michael B. Wallace
    Role of EUS in patients with suspected Barrett’s esophagus with high-grade dysplasia or early esophageal adenocarcinoma: impact on endoscopic therapy
    Endoscopic therapy is the standard treatment for high-grade dysplasia and some cases of T1a esophageal adenocarcinoma (EAC), but it is not appropriate for deeply invasive disease. Data on the value of EUS for patient selection for endoscopic or surgical resection are conflicting. We investigated the outcome of esophageal EUS for the staging and treatment selection of patients with treatment-naive, premalignant Barrett’s esophagus (BE) and suspected superficial EAC.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Michael J. Levy, Steven R. Alberts, William R. Bamlet, Patrick A. Burch, Michael B. Farnell, Ferga C. Gleeson, Michael G. Haddock, Michael L. Kendrick, Ann L. Oberg, Gloria M. Petersen, Naoki Takahashi, Suresh T. Chari
    EUS-guided fine-needle injection of gemcitabine for locally advanced and metastatic pancreatic cancer
    Among the greatest hurdles to pancreatic cancer (PC) therapy is the limited tissue penetration of systemic chemotherapy because of tumor desmoplasia. The primary study aim was to determine the toxicity profile of EUS-guided fine-needle injection (EUS-FNI) with gemcitabine. Secondary endpoints included the ability to disease downstage leading to an R0 resection and overall survival (OS) at 6 months, 12 months, and 5 years after therapy.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Seung Hun Kang, Yoon Tae Jeen, Jae Hyung Lee, In Kyung Yoo, Jae Min Lee, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Hong Sik Lee, Hoon Jai Chun, Chang Duck Kim
    Comparison of a split-dose bowel preparation with 2L polyethylene glycol plus ascorbic acid and 1L polyethylene glycol plus ascorbic acid and bisacodyl before colonoscopy
    Recently a low-volume polyethylene glycol containing ascorbic acid (PEG-Asc) formulation has proven as safe and effective as traditional 4L PEG solutions for colonoscopy preparation. However, currently available aqueous purgative formulations are poorly tolerated. The aim of this study was to compare a split-dose 2L PEG-Asc and a 1L PEG-Asc with bisacodyl (10 mg) formulation to determine the quality of bowel cleansing and patient tolerability.


    Date de mise en ligne : Mardi 22 novembre 2016
    James W. Walter, William Klump, Francis Spitz, Adam Elfant, Henry C. Ho
    A large degenerated GI stromal tumor presenting as a peripancreatic cyst
    A 21-year-old man presented to the hospital with progressive abdominal distension. On examination, there was a palpable midline mass. CT demonstrated a well-circumscribed, septated, cystic mass in the left upper quadrant, measuring approximately 18 cm (A). EUS demonstrated a normal pancreas with a distinct septated mass (B). FNA yielded 30 mL of amber fluid that demonstrated a paucicellular specimen with proteinaceous debris and rare glandular cells. Fluid chemistry determinations showed carcinoembryonic antigen 0.9 ng/mL and amylase 15 U/L.


    Date de mise en ligne : Samedi 19 novembre 2016
    Huiyun Zhu, Yuanhang Dong, Pei Xie, Zhendong Jin, Yiqi Du
    Cumbersome removal of a lumen-apposing metal stent in a case of refractory pancreatic pseudocyst
    A 32-year-old man with previous severe pancreatitis received a diagnosis of pancreatic pseudocyst and was treated by 3 different methods of drainage. There was no communication between the pseudocyst and the pancreatic duct. The pseudocyst was first discovered 3 years previously (A) and was treated by percutaneous drainage. One year later, in August 2014, the patient presented with abdominal pain and distension again, and EUS showed a huge pseudocyst (15 cm × 15 cm) in the body of the pancreas. We placed a biliary metal stent under the guidance of EUS and removed it 4 months later, but the pseudocyst recurred afterward.


    Date de mise en ligne : Samedi 19 novembre 2016
    Roberto Grassia, Elena Iiritano, Katerina Vjero, Fabrizio Cereatti, Pietro Capone, Federico Buffoli
    Severe acute diverticular bleeding: successful treatment with hemostatic powder
    A 50-year-old man was admitted to the intensive coronary care unit for acute myocardial infarction and was treated by coronary artery stenting and dual antiplatelet therapy. On postprocedure day 5, the patient presented with massive hematochezia, anemia (hemoglobin 10.4 g/dL), and hypovolemic shock. After hemodynamic stabilization, a mesenteric angiogram revealed a left-sided colonic hemorrhage highly suggestive of diverticular bleeding (A, white arrow). Selective embolization was ruled out because of the risk of bowel infarction.


    Date de mise en ligne : Jeudi 17 novembre 2016
    Tarun Rustagi, Shayan Irani, D. Nageshwar Reddy, Barham K. Abu Dayyeh, Todd H. Baron, Christopher J. Gostout, Michael J. Levy, John Martin, Bret T. Petersen, Andrew Ross, Mark D. Topazian
    Radiofrequency ablation for intraductal extension of ampullary neoplasms
    Extension of ampullary adenomas into the common bile duct (CBD) or pancreatic duct (PD) may be difficult to treat endoscopically. We evaluated the feasibility, safety, and efficacy of endoscopic radiofrequency ablation (RFA) in the management of ampullary neoplasms with intraductal extension.


    Date de mise en ligne : Vendredi 11 novembre 2016
    Sundeep Lakhtakia, Jahangeer Basha, Rupjyoti Talukdar, Rajesh Gupta, Zaheer Nabi, Mohan Ramchandani, B.V.N. Kumar, Partha Pal, Rakesh Kalpala, P. Manohar Reddy, R. Pradeep, Jagadish R. Singh, G.V. Rao, D. Nageshwar Reddy
    Endoscopic “step-up approach” using a dedicated biflanged metal stent reduces the need for direct necrosectomy in walled-off necrosis (with videos)
    EUS-guided drainage using plastic stents may be inadequate for treatment of walled-off necrosis (WON). Recent studies report variable outcomes even when using covered metal stents. The aim of this study was to evaluate the efficacy of a dedicated covered biflanged metal stent (BFMS) when adopting an endoscopic “step-up approach” for drainage of symptomatic WON.


    Date de mise en ligne : Jeudi 03 novembre 2016
    Saurabh Sethi, Robert J. Huang, Monique T. Barakat, Niaz Banaei, Shai Friedland, Subhas Banerjee
    Adenosine triphosphate bioluminescence for bacteriologic surveillance and reprocessing strategies for minimizing risk of infection transmission by duodenoscopes
    Recent outbreaks of duodenoscope-transmitted infections underscore the importance of adequate endoscope reprocessing. Adenosine triphosphate (ATP) bioluminescence testing allows rapid evaluation of endoscopes for bacteriologic/biologic residue. In this prospective study we evaluate the utility of ATP in bacteriologic surveillance and the effects of endoscopy staff education and dual cycles of cleaning and high-level disinfection (HLD) on endoscope reprocessing.


    Date de mise en ligne : Mercredi 02 novembre 2016
    Shaffer R.S. Mok, Henry C. Ho, Paurush Shah, Milan Patel, John P. Gaughan, Adam B. Elfant
    Lactated Ringer's solution in combination with rectal indomethacin for prevention of post-ERCP pancreatitis and readmission: a prospective randomized, double-blinded, placebo-controlled trial
    Prospective data have shown the benefit of rectal indomethacin (IND) for preventing post-ERCP pancreatitis (PEP). A recent pilot study demonstrated a lower incidence of PEP after an 8-hour lactated Ringer’s solution (LR) infusion. The aim of this study was to evaluate the efficacy of IND with or without bolus LR in patients at high-risk for PEP.


    Date de mise en ligne : Mardi 01 novembre 2016
    Vladimir Milivojevic, Ivan Rankovic, Ljiljana Milic, Vasilije Jeremic, Ivan Jovanovic
    Mobile phone in the stomach: call the emergency endoscopist!
    A 39-year-old man presented to the emergency department with profuse melena accompanied by lightheadedness and vertigo. He reported having had 4 black, tarry stools during the past day and acknowledged having taken nonsteroidal anti-inflammatory drugs (NSAIDs) for the past 2 months for abdominal pain. In his personal history, cerebral palsy was present. Clinical and laboratory investigations yielded a Glasgow-Blatchford score of 8. Emergency endoscopy verified large amounts of hematin in his stomach; thus, the patient was referred to the surgical intensive care unit, where he received supportive and pharmacotherapeutic measures.


    Date de mise en ligne : Mardi 01 novembre 2016
    Layth Al-Jashaami, Rashmi Kumar, Rakesh Nanda
    A ribbon in the esophagus
    A 96-year-old man with a history of hypertension and inguinal hernia presented with a “sore throat” of 6 months’ duration, progressively getting worse, associated with a productive yellowish cough and occasional nausea and vomiting, mainly occurring in the evening after eating dinner. He was very active; he walked 4 to 5 miles daily when playing golf 5 days a week and did not use a golf cart! He had quit smoking at age 50 and abstained from alcohol. The results of his physical examination were unremarkable, and laboratory tests showed normal results.


    Date de mise en ligne : Lundi 31 octobre 2016
    Apostolos V. Tsolakis, Paul D. James, Gilaad G. Kaplan, Robert P. Myers, James Hubbard, Todd Wilson, Scott Zimmer, Rachid Mohamed, Martin Cole, Sydney Bass, Mark G. Swain, Steven J. Heitman
    Clinical prediction rule to determine the need for repeat ERCP after endoscopic treatment of postsurgical bile leaks
    In patients who have undergone ERCP with biliary stenting for postsurgical bile leaks, the optimal method (ERCP or gastroscopy) and timing of stent removal is controversial. We developed a clinical prediction rule to identify cases in which a repeat ERCP is unnecessary.


    Date de mise en ligne : Jeudi 20 octobre 2016
    Tarun Rustagi, Ferga C. Gleeson, Suresh T. Chari, Barham K. Abu Dayyeh, Michael B. Farnell, Prasad G. Iyer, Michael L. Kendrick, Randall K. Pearson, Bret T. Petersen, Elizabeth Rajan, Mark D. Topazian, Mark J. Truty, Santhi S. Vege, Kenneth K. Wang, Michael J. Levy
    Remote malignant intravascular thrombi: EUS-guided FNA diagnosis and impact on cancer staging
    Malignant vascular invasion usually results from gross direct infiltration from a primary tumor and impacts cancer staging, prognosis, and therapy. However, patients may also develop a remote malignant thrombi (RMT), defined as a malignant intravascular thrombus located remote and noncontiguous to the primary tumor. Our aim was to compare EUS, CT, and magnetic resonance imaging (MRI) findings of RMT and to explore the potential impact on cancer staging.


    Date de mise en ligne : Samedi 15 octobre 2016
    Eun Hye Kim, Jun Chul Park, In Ji Song, Yeong Jin Kim, Dong Hoo Joh, Kyu Yeon Hahn, Yong Kang Lee, Ha Yan Kim, Hyunsoo Chung, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
    Prediction model for non-curative resection of endoscopic submucosal dissection in patients with early gastric cancer
    Endoscopic submucosal dissection (ESD) is a useful method for complete resection of early gastric cancer (EGC). However, there are still some patients who undergo additional gastrectomy after ESD because of non-curative resection. There is no model that can accurately predict non-curative resection of ESD. We aimed to create a model for predicting non-curative resection of ESD in patients with EGC.


    Date de mise en ligne : Samedi 15 octobre 2016
    Shinsuke Koshita, Yutaka Noda, Kei Ito, Yoshihide Kanno, Takahisa Ogawa, Kaori Masu, Yoshiharu Masaki, Jun Horaguchi, Masaya Oikawa, Takashi Tsuchiya, Takashi Sawai, Miwa Uzuki, Fumiyoshi Fujishima
    Pancreatic juice cytology with immunohistochemistry to detect malignancy and histologic subtypes in patients with branch duct type intraductal papillary mucinous neoplasms of the pancreas
    The aim of this study was to elucidate the efficacy of pancreatic juice cytology with the cell-block method (CB-PJC) for the determination of surgery in patients with branch duct intraductal papillary mucinous neoplasm (BD-IPMN).


    Date de mise en ligne : Samedi 15 octobre 2016
    Amy Tyberg, Stefan Seewald, Reem Z. Sharaiha, Guadalupe Martinez, Amit P. Desai, Nikhil A. Kumta, Arnon Lambroza, Amrita Sethi, Kevin M. Reavis, Ketisha DeRoche, Monica Gaidhane, Michael Talbot, Payal Saxena, Felipe Zamarripa, Maximilien Barret, Nicholas Eleftheriadis, Valerio Balassone, Haruhiro Inoue, Michel Kahaleh
    A multicenter international registry of redo per-oral endoscopic myotomy (POEM) after failed POEM
    Per-oral endoscopic myotomy (POEM) has become an accepted treatment for patients with achalasia. Despite its excellent efficacy rate of greater than 80%, a small percentage of patients remain symptomatic after the procedure. Limited data exist as to the best management for recurrence of symptoms after POEM. We present the first international, multicenter experience on the efficacy and safety of a repeat POEM in the management of achalasia.


    Date de mise en ligne : Samedi 15 octobre 2016
    Shannon Melissa Chan, Anthony Yuen Bun Teoh, Hon Chi Yip, Vivien Wai Yin Wong, Philip Wai Yan Chiu, Enders Kwok Wai Ng
    Feasibility of per-oral cholecystoscopy and advanced gallbladder interventions after EUS-guided gallbladder stenting (with video)
    The recent development of EUS-guided gallbladder drainage (EGBD) with a lumen-apposing stent has made endoscopic assessment and advanced gallbladder interventions via the stent possible. The aim of this study was to assess the feasibility and safety of per-oral cholecystoscopy and the types of gallbladder interventions that can be performed.


    Date de mise en ligne : Vendredi 14 octobre 2016
    Masau Sekiguchi, Ichiro Oda, Haruhisa Suzuki, Seiichiro Abe, Satoru Nonaka, Shigetaka Yoshinaga, Hirokazu Taniguchi, Shigeki Sekine, Yutaka Saito
    Clinical outcomes and prognostic factors in gastric cancer patients aged ≥85 years undergoing endoscopic submucosal dissection
    Although the number of gastric cancer patients aged ≥85 years indicated for endoscopic submucosal dissection (ESD) has increased, little is known about the outcomes and prognostic factors. This study aimed to investigate the clinical outcomes and prognostic factors for overall survival (OS) of patients aged ≥85 years who underwent ESD for gastric cancer.


    Date de mise en ligne : Vendredi 14 octobre 2016
    Shigehisa Aoki, Yasuhisa Sakata, Ryo Shimoda, Toshiaki Takezawa, Ayumi Oshikata-Miyazaki, Hiromi Kimura, Mihoko Yamamoto, Ryuichi Iwakiri, Kazuma Fujimoto, Shuji Toda
    High-density collagen patch prevents stricture after endoscopic circumferential submucosal dissection of the esophagus: a porcine model
    Extensive excision of the esophageal mucosa by endoscopic submucosal dissection (ESD) frequently evokes a luminal stricture. This study aimed to determine the efficacy of a high-density collagen patch for the prevention of esophageal stricture in extensive ESD.


    Date de mise en ligne : Jeudi 06 octobre 2016
    Seifeldin Hakim, Tusar Desai, Mitchell S. Cappell
    Esophageal hemangiomatosis with chest CT revealing a fine, curvilinear, calcified thrombus within the esophagus simulating acute esophageal fishbone impaction: first reported endoscopic photograph of GI manifestations in Maffucci syndrome
    A 70-year-old-man with known Maffucci syndrome (confirmed by pathologic analysis of biopsy specimens of enchondromas and hemangiomas), who had undergone resection/amputation of left thumb chondrosarcoma 15 years earlier, without known angina or cardiac disease, presented with sudden onset of substernal chest pain, without dysphagia or vomiting, commencing 1 hour after he had eaten a cooked, whole catfish with bones. Physical examination revealed normal vital signs; normal oropharyngeal, cardiac, and abdominal examination results; and numerous 8-mm to 30-mm-wide nodules, mostly on the left arm and leg, with rare right-sided nodules, consisting of 2 tumor populations: indurated pale enchondromas and soft compressible bluish hemangiomas (A, B, numerous enchondromas and hemangiomas on the [A] dorsal and [B] volar surfaces of the left hand).


    Date de mise en ligne : Jeudi 06 octobre 2016
    Vincent Ganapini, Maryconi Jaurigue, Mitual Amin, Gehad Ghaith, Mitchell S. Cappell
    ERCP for diagnosis and extraction of choledochal phytobezoar causing right upper quadrant abdominal pain and cholestasis in a patient without prior sphincterotomy or biliary instrumentation
    A 72-year-old white man with diabetes mellitus and gastroesophageal reflux, with no history of liver disease, hepatobiliary instrumentation, sphincterotomy, or abdominal trauma, presented with acute right upper quadrant abdominal pain and diaphoresis that had started 1 hour earlier. Physical examination revealed a soft and nontender abdomen. The initial serum liver function test results were all within normal limits but rose acutely to a serum alkaline phosphatase of 224 U/L, aspartate aminotransferase of 355 U/L, alanine aminotransferase of 531 U/L, and total bilirubin of 2.4 mg/dL after 48 hours.


    Date de mise en ligne : Mardi 04 octobre 2016
    Douglas G. Adler
    Esophageal placement of a lumen-apposing metal stent in a patient with a chronic anastomotic stricture
    In 2010, a 59-year-old man experienced adenocarcinoma of the distal esophagus, which involved the periesophageal and mediastinal nodes. He received cisplatin and paclitaxel with radiation. He subsequently underwent transhiatal esophagectomy and has been without evidence of cancer since then. Postoperatively, he experienced a chronic anastomotic stricture with dysphagia and several chronic tracheoesophageal fistulas treated with esophageal and airway stents. In the intervening years, the patient has undergone multiple rounds of esophageal stenting for dysphagia with fully covered stents, but these were removed because he was experiencing coughing, discomfort, and mucous production.


    Date de mise en ligne : Lundi 03 octobre 2016
    Linda Zhang, Paul Edwards, Milan Bassan
    Thoracic osteomyelitis: an unusual adverse event of esophageal stenting
    A 51-year-old man presented with a 3-week history of interscapular pain and night sweats. He had been treated with chemoradiotherapy 15 months earlier for a locally advanced esophageal squamous cell carcinoma 25 cm aboral with complete response on subsequent restaging. A tracheoesophageal fistula (TEF) developed 3 months after chemoradiotherapy 30 cm aboral, initially managed with placement of a 23 mm × 105 mm fully covered esophageal self-expandable metal stent (SEMS) and placement of an overlapping 23 mm × 155 mm fully covered SEMS 6 months later because of stent migration and recurrent aspiration.


    Date de mise en ligne : Vendredi 30 septembre 2016
    Adriana Vaz Safatle-Ribeiro, Elisa Ryoka Baba, Sheila Friedrich Faraj, Juliana Trazzi Rios, Marcelo Simas de Lima, Bruno Costa Martins, Sebastian Naschold Geiger, Caterina Pennacchi, Carla Gusman, Fábio Shiguehissa Kawaguti, Ricardo Sato Uemura, Evandro Sobroza de Melo, Ulysses Ribeiro, Fauze Maluf-Filho
    Diagnostic accuracy of probe-based confocal laser endomicroscopy in Lugol-unstained esophageal superficial lesions of patients with head and neck cancer
    Surveillance programs of patients with head and neck cancer (HNC) detect synchronous or metachronous esophageal squamous cell carcinoma (ESCC) in up to 15% of patients. Noninvasive, probe-based confocal laser endomicroscopy (pCLE) technique may improve the diagnosis allowing acquisition of high-resolution in vivo images at the cellular and microvascular levels. The aim of this study was to evaluate the accuracy of pCLE for the differential diagnosis of nonneoplastic and neoplastic Lugol-unstained esophageal lesions in patients with HNC.


    Date de mise en ligne : Jeudi 29 septembre 2016
    Navin L. Kumar, Aaron J. Cohen, Jennifer Nayor, Brian L. Claggett, John R. Saltzman
    Timing of upper endoscopy influences outcomes in patients with acute nonvariceal upper GI bleeding
    Current guidelines advise that upper endoscopy be performed within 24 hours of presentation in patients with acute nonvariceal upper GI bleeding (UGIB). However, the role of urgent endoscopy (<12 hours) is controversial. Our aim was to assess whether patients admitted with acute nonvariceal UGIB with lower-risk versus high-risk bleeding have different outcomes with urgent compared with nonurgent endoscopy.


    Date de mise en ligne : Jeudi 29 septembre 2016
    Selma J. Lekkerkerker, Marc G. Besselink, Olivier R. Busch, Joanne Verheij, Marc R. Engelbrecht, Erik A. Rauws, Paul Fockens, Jeanin E. van Hooft
    Comparing 3 guidelines on the management of surgically removed pancreatic cysts with regard to pathological outcome
    Currently, 3 guidelines are available for the management of pancreatic cysts. These guidelines vary in their indication for resection of high-risk cysts. We retrospectively compared the final pathologic outcome of surgically removed pancreatic cysts with the indications for resection according to 3 different guidelines.


    Date de mise en ligne : Jeudi 29 septembre 2016
    Jason Y. Huang, Jason B. Samarasena, Takeshi Tsujino, John Lee, Ke-Qin Hu, Christine E. McLaren, Wen-Pin Chen, Kenneth J. Chang
    EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study
    Portal hypertension (PH) is a serious adverse event of liver cirrhosis. The hepatic venous pressure gradient or portal pressure gradient (PPG) accurately reflects the degree of PH and is the single best prognostic indicator in liver disease. This is usually obtained by interventional radiology (IR), although it is not routinely performed. Recently, we developed a simple novel technique for EUS-guided PPG measurement (PPGM). Our animal studies showed excellent correlation between EUS-PPGM and IR-PPGM.


    Date de mise en ligne : Lundi 26 septembre 2016
    Dennis Yang, Roxana M. Coman, Michel Kahaleh, Irving Waxman, Andrew Y. Wang, Amrita Sethi, Ashish R. Shah, Peter V. Draganov
    Endoscopic submucosal dissection for Barrett’s early neoplasia: a multicenter study in the United States
    The role of endoscopic submucosal dissection (ESD) in Barrett’s early neoplasia is not well defined, with most studies originating from Asia and Europe. We aimed to assess the efficacy, safety, and results of ESD in Barrett’s esophagus (BE) with high-grade dysplasia (HGD) and early adenocarcinoma (EAC) across centers in the United States.


    Date de mise en ligne : Mardi 20 septembre 2016
    Saowanee Ngamruengphong, Haruhiro Inoue, Philip Wai-Yan Chiu, Hon Chi Yip, Amol Bapaye, Michael Ujiki, Lava Patel, Pankaj N. Desai, Bu Hayee, Amyn Haji, Vivien Wai-yin Wong, Silvana Perretta, Shivangi Dorwat, Mathieu Pioche, Sabine Roman, Jérôme Rivory, François Mion, Thierry Ponchon, Aurélien Garros, Jun Nakamura, Yoshitaka Hata, Valerio Balassone, Manabu Onimaru, Gulara Hajiyeva, Amr Ismail, Yen-I Chen, Majidah Bukhari, Yamile Haito-Chavez, Vivek Kumbhari, Roberta Maselli, Alessandro Repici, Mouen A. Khashab
    Long-term outcomes of per-oral endoscopic myotomy in patients with achalasia with a minimum follow-up of 2 years: an international multicenter study
    Per-oral endoscopic myotomy (POEM) has shown promising safety and efficacy in short-term studies. However, long-term follow-up data are very limited. The aims of this study were to assess (1) clinical outcome of patients with a minimum post-POEM follow-up of 2 years and (2) factors associated with long-term clinical failure after POEM.


    Date de mise en ligne : Mardi 20 septembre 2016
    Cetin Karaca, Ebubekir S. Daglilar, Ozlem Mutluay Soyer, Mine Gulluoglu, William R. Brugge
    Endoscopic submucosal resection of gastric subepithelial lesions smaller than 20 mm: a comparison of saline solution–assisted snare and cap band mucosectomy techniques
    Application of endoscopic submucosal resection (ESMR) in the management of gastric subepithelial lesions (GSLs) less than 20 mm is gradually increasing because it allows diagnosis and treatment at the same operative session. In this study, we compare and evaluate the benefits of ESMR with an endoscopic cap band mucosectomy technique or saline solution–assisted snare technique in GSLs smaller than 20 mm.


    Date de mise en ligne : Lundi 19 septembre 2016
    Anne-Fré Swager, Guillermo J. Tearney, Cadman L. Leggett, Martijn G.H. van Oijen, Sybren L. Meijer, Bas L. Weusten, Wouter L. Curvers, Jacques J.G.H.M. Bergman
    Identification of volumetric laser endomicroscopy features predictive for early neoplasia in Barrett’s esophagus using high-quality histological correlation
    Volumetric laser endomicroscopy (VLE) provides a circumferential scan that enables visualization of the subsurface layers of the esophageal wall at 7 μm resolution. The aims of this study were to identify VLE features of Barrett's esophagus (BE) neoplasia and to develop a VLE prediction score.


    Date de mise en ligne : Samedi 17 septembre 2016
    Kook Hyun Kim, Kathleen McGreevy, Kristin La Fortune, Harvey Cramer, John DeWitt
    Sonographic and cyst fluid cytologic changes after EUS-guided pancreatic cyst ablation
    The effect of EUS-guided pancreatic cyst ablation (PCA) on sonographic morphology and cyst fluid cytology is unknown. The aim of this study was to evaluate morphologic, cytologic, and change in cyst fluid DNA after PCA.


    Date de mise en ligne : Samedi 17 septembre 2016
    Dong Hui Cho, Sang Soo Lee, Dongwook Oh, Tae Jun Song, Do Hyun Park, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim
    Long-term outcomes of a newly developed hybrid metal stent for EUS-guided biliary drainage (with videos)
    Although fully covered self-expandable metal stents (FCSEMSs) have been commonly used for EUS-guided biliary drainage (EUS-BD), FCSEMS migration is a main limitation of this procedure. In the present study we evaluated the technical and clinical success rates, adverse events, and long-term outcomes of a newly developed hybrid stent that has been customized for EUS-BD.


    Date de mise en ligne : Lundi 12 septembre 2016
    Manu K. Nayar, Bharat Paranandi, Muhammad F. Dawwas, John S. Leeds, Antony Darne, Beate Haugk, Debasis Majumdar, Muna M. Ahmed, Kofi W. Oppong
    Comparison of the diagnostic performance of 2 core biopsy needles for EUS-guided tissue acquisition from solid pancreatic lesions
    A new core biopsy needle with a novel tip, opposing bevel, and sheath design has recently been introduced for EUS-guided fine-needle biopsy (FNB). The diagnostic utility of this needle for differentiating solid pancreatic masses is currently unknown. The aim of this study was to compare the diagnostic performance and yield for tissue acquisition from solid pancreatic lesions of the opposing bevel needle with those of a reverse bevel EUS-FNB needle.


    Date de mise en ligne : Lundi 12 septembre 2016
    Shayan Irani, Sujai Jalaj, Andrew Ross, Michael Larsen, Ian S. Grimm, Todd H. Baron
    Use of a lumen-apposing metal stent to treat GI strictures (with videos)
    Benign GI strictures occur typically in the esophagus and pyloric channel but can occur anywhere in the GI tract and at anastomotic sites. Such strictures can be treated with dilation, incisional therapy, steroid injection, and stents. Our aim was to describe the use of a lumen-apposing metal stent (LAMS) to treat short, benign GI strictures.


    Date de mise en ligne : Samedi 10 septembre 2016
    Folasade P. May, Mark W. Reid, Samuel Cohen, Francis Dailey, Brennan M.R. Spiegel
    Predictive overbooking and active recruitment increases uptake of endoscopy appointments among African American patients
    Use of GI endoscopy is historically lower in nonwhite ethnic and racial groups compared with whites. These disparities are multifactorial but likely contribute to differences in GI clinical outcomes. We sought to improve endoscopy uptake overall and in minorities by predictive overbooking and active recruitment in a hospital-based GI clinic.


    Date de mise en ligne : Samedi 10 septembre 2016
    Tomas DaVee, Sunil K. Geevarghese, James C. Slaughter, Patrick S. Yachimski
    Refractory anastomotic bile leaks after orthotopic liver transplantation are associated with hepatic artery disease
    Anastomotic bile leaks are common after orthotopic liver transplant (OLT), and standard treatment consists of placement of a biliary endoprosthesis. The objectives of this study were to identify risk factors for refractory anastomotic bile leaks and to determine the morbidity associated with refractory bile leaks after OLT.


    Date de mise en ligne : Samedi 10 septembre 2016
    Stig B. Laursen, Grigorios I. Leontiadis, Adrian J. Stanley, Morten H. Møller, Jane M. Hansen, Ove B. Schaffalitzky de Muckadell
    Relationship between timing of endoscopy and mortality in patients with peptic ulcer bleeding: a nationwide cohort study
    The optimal timing of endoscopy in patients with peptic ulcer bleeding (PUB) remains unclear. The aim of this study was to examine the association between timing of endoscopy and mortality in PUB.


    Date de mise en ligne : Vendredi 09 septembre 2016
    Sung Ill Jang, Kwang-Hun Lee, Hong Jin Yoon, Dong Ki Lee
    Treatment of completely obstructed benign biliary strictures with magnetic compression anastomosis: follow-up results after recanalization
    Although nonsurgical methods produce high clinical success rates in the treatment of benign biliary stricture (BBS), conventional methods are not always successful in cases of severe biliary stricture or complete obstruction. Therefore, the efficacy of magnetic compression anastomosis (MCA) for treatment of refractory BBS was evaluated in a single-center, nonrandomized study.


    Date de mise en ligne : Mardi 06 septembre 2016
    Mihir S. Wagh, Peter V. Draganov
    Per-oral endoscopic tunneling for restoration of the esophagus: a novel endoscopic submucosal dissection technique for therapy of complete esophageal obstruction
    Total aphagia from complete esophageal obstruction (CEO) can be seen in patients with head–neck or thoracic malignancies undergoing chemoradiation or surgery. Combined antegrade and retrograde endoscopy (via gastrostomy tube [G-tube] tract) is often performed for esophageal reconstruction but is limited by the length of the obstructed esophagus. We describe per-oral endoscopic tunneling for restoration of the esophagus (POETRE) for patients with longer segments of esophageal obstruction. The aim of this study was to assess the efficacy and safety of POETRE for CEO.


    Date de mise en ligne : Lundi 05 septembre 2016
    Yuki B. Werner, Daniel von Renteln, Tania Noder, Guido Schachschal, Ulrike W. Denzer, Stefan Groth, Jan F. Nast, Jan F. Kersten, Martin Petzoldt, Gerhard Adam, Oliver Mann, Alessandro Repici, Cesare Hassan, Thomas Rösch
    Early adverse events of per-oral endoscopic myotomy
    The recently developed technique of per-oral endoscopic myotomy (POEM) has been shown to be effective for the therapy of esophageal motility disorders. Limited information is available about POEM adverse events (AEs).


    Date de mise en ligne : Vendredi 02 septembre 2016
    Young Koog Cheon, Tae Yoon Lee, Soo-Nyung Kim, Chan Sup Shim
    Impact of endoscopic papillary large-balloon dilation on sphincter of Oddi function: a prospective randomized study
    Endoscopic papillary balloon dilation (≤8 mm in diameter) preserves sphincter of Oddi (SO) function. However, it is still unknown whether papillary function is preserved after endoscopic papillary large-balloon dilation (EPLBD, ≥12 mm in diameter). We investigated SO function after EPLBD with or without endoscopic sphincterotomy (EST) by endoscopic manometry, up to 1 year after the procedure.


    Date de mise en ligne : Mardi 30 août 2016
    Basile Njei, Thomas R. McCarty, Shyam Varadarajulu, Udayakumar Navaneethan
    Cost utility of ERCP-based modalities for the diagnosis of cholangiocarcinoma in primary sclerosing cholangitis
    Cholangiocarcinoma (CCA) is a leading cause of morbidity and mortality in patients with primary sclerosing cholangitis (PSC). Although several ERCP-based diagnostic modalities are available for diagnosing CCA, it is unclear whether one modality is more cost-effective than the others. The primary aim of this study was to compare the cost-effectiveness of ERCP-based techniques for diagnosing CCA in patients with PSC-induced biliary strictures.


    Date de mise en ligne : Jeudi 25 août 2016
    Badr Al-Bawardy, Elizabeth Rajan, Louis M. Wong Kee Song
    Over-the-scope clip-assisted endoscopic full-thickness resection of epithelial and subepithelial GI lesions
    Endoscopic full-thickness resection (EFTR) allows for definitive diagnosis and treatment of select subepithelial and epithelial lesions unsuitable to conventional resection techniques. Our aim was to evaluate the efficacy and safety of over-the-scope (OTS) clip-assisted EFTR for these lesions.


    Date de mise en ligne : Jeudi 25 août 2016
    Douglas G. Adler, Georgios I. Papachristou, Linda Jo Taylor, Tyler McVay, Madeleine Birch, Gloria Francis, Andrew Zabolotsky, Sobia N. Laique, Umar Hayat, Tingting Zhan, Rohit Das, Adam Slivka, Mordechai Rabinovitz, Satish Munigala, Ali A. Siddiqui
    Clinical outcomes in patients with bile leaks treated via ERCP with regard to the timing of ERCP: a large multicenter study
    Postsurgical or traumatic bile duct leaks (BDLs) can be safely and effectively managed by endoscopic therapy via ERCP. The early diagnosis of BDL is important because unrecognized leaks can lead to serious adverse events (AEs). Our aim was to evaluate the relationship between timing of endotherapy after BDL and the clinical outcomes, AEs, and long-term results of endoscopic therapy.


    Date de mise en ligne : Mercredi 24 août 2016
    Pouya Iranmanesh, Olivier Tobler, Sandra De Sousa, Jean-Louis Frossard, Philippe Morel, Christian Toso
    Prospective validation of an initial cholecystectomy strategy for patients at intermediate-risk of common bile duct stone
    Initial cholecystectomy for patients at intermediate risk of common bile duct (CBD) stones (including increased liver function tests but bilirubin <4 mg/dL and no cholangitis) showed shorter length of stay and fewer CBD investigations without increased morbidity compared with sequential CBD endoscopic assessment and subsequent cholecystectomy in a randomized controlled trial. The objectives were to prospectively validate these results in daily clinical practice and discuss current guidelines.


    Date de mise en ligne : Mardi 23 août 2016
    Ali A. Siddiqui, Thomas E. Kowalski, David E. Loren, Ammara Khalid, Ayesha Soomro, Syed M. Mazhar, Laura Isby, Michel Kahaleh, Kunal Karia, Joseph Yoo, Andrew Ofosu, Beverly Ng, Reem Z. Sharaiha
    Fully covered self-expanding metal stents versus lumen-apposing fully covered self-expanding metal stent versus plastic stents for endoscopic drainage of pancreatic walled-off necrosis: clinical outcomes and success
    Endoscopic transmural drainage/debridement of pancreatic walled-off necrosis (WON) has been performed using double-pigtail plastic (DP), fully covered self-expanding metal stents (FCSEMSs), or the novel lumen-apposing fully covered self-expanding metal stent (LAMS). Our aim was to perform a retrospective cohort study to compare the clinical outcomes and adverse events of EUS-guided drainage/debridement of WON with DP stents, FCSEMSs, and LAMSs.


    Date de mise en ligne : Mardi 23 août 2016
    Jong Jin Hyun, Tae Hoon Lee, Jin-Seok Park, Joung-Ho Han, Seok Jeong, Seon Mee Park, Hong Sik Lee, Jong Ho Moon, Sang-Heum Park
    A prospective multicenter study of submucosal injection to improve endoscopic snare papillectomy for ampullary adenoma
    Whether or not submucosal injection of a diluted epinephrine solution should be used to lift ampullary tumors during endoscopic snare papillectomy is unclear. This study aimed to investigate the clinical efficacy of a simple snaring method versus submucosal injection for papillectomy.


    Date de mise en ligne : Mardi 23 août 2016
    Erkan Parlak, Aydın Seref Koksal, Fahrettin Kucukay, Ahmet Tarık Eminler, Bilal Toka, Mustafa Ihsan Uslan
    A novel technique for the endoscopic treatment of complete biliary anastomosis obstructions after liver transplantation: through-the-scope magnetic compression anastomosis
    Magnetic compression anastomosis is a rescue technique for recanalization of complete biliary strictures. Here, we present magnetic compression anastomosis with novel through-the-scope magnets in patients with complete duct-to-duct anastomosis obstruction after liver transplantation.


    Date de mise en ligne : Mardi 23 août 2016
    Eelco C. Brand, Raouf E. Nakhleh, Michael B. Wallace
    Pseudoinvasion appearing as a deeply invasive malignant colorectal polyp
    A 50-year-old man with alcoholic liver cirrhosis and a Model for End-Stage Liver Disease score of 15 underwent colonoscopy as part of his evaluation and screening for liver transplantation. A malignant-appearing 20-mm sessile polyp with an ulcerated surface, Paris IIa/III, was seen in a tight area of the sigmoid. Owing to notable contractions, the polyp prolapsed into the lumen. The polyp surface, assessed with high-definition near-focus white-light and narrow-band imaging (CF-HQ190, Olympus Corp, Center Valley, Pa), demonstrated a Sano IIIb and Kudo Vn pattern for the ulcer and Sano II for the sharply demarcated margins, suggestive of deep submucosal invasion (A).


    Date de mise en ligne : Mardi 23 août 2016
    Vincent Huberty, Mostafa Ibrahim, Martin Hiernaux, Alexandre Chau, Sonia Dugardeyn, Jacques Devière
    Safety and feasibility of an endoluminal-suturing device for endoscopic gastric reduction (with video)
    Obesity is a major pandemic disease. Surgical therapy is highly effective, but its availability will likely be overwhelmed by the burden of the disease. Endoscopic technologies that could reproduce some of the clinical effects of surgery may become part of the treatment armamentarium. A simple transoral restrictive procedure could play a role in first-line surgical management.


    Date de mise en ligne : Samedi 13 août 2016
    Lisa S. Cassani, Gandhi Lanke, Hsiang-Chun Chen, Xuemei Wang, Patrick Lynch, Jeffrey H. Lee
    Comparison of nonampullary duodenal adenomas in patients with familial adenomatous polyposis versus patients with sporadic adenomas
    Nonampullary duodenal adenomas are either sporadic or associated with a hereditary syndrome such as familial adenomatous polyposis (FAP). The aim of this study is to compare characteristics and outcomes of sporadic and FAP-associated duodenal adenomas.


    Date de mise en ligne : Lundi 01 août 2016
    Rintaro Hashimoto, Tomoki Matsuda, Hayato Aoki, Toru Okuzono, Masato Nakahori
    Double-balloon assisted trans-anal ERCP in a patient with Roux-en-Y choledochojejunostomy
    A 66-year-old man was referred to our hospital with fever and elevated liver enzymes. His medical history was significant for Roux-en-Y choledochojejunostomy performed because of iatrogenic bile duct injury during cholecystectomy a few years earlier. CT showed biliary tract dilatation and some small liver abscesses. Endoscopic sonography revealed mild dilatation of the common bile duct (CBD). Drip infusion cholecystocholangiography/computed tomography revealed the stenosis at the anastomosis. These results led to a diagnosis of acute cholangitis due to a postoperative CBD stricture.


    Date de mise en ligne : Lundi 01 août 2016
    Yasuyuki Tanaka, Takeharu Nakamura, Shigehiko Fujii, Toshihiro Kusaka
    Successful treatment of a perforated duodenal ulcer with polyglycolic acid sheets
    An 86-year-old woman was admitted to our hospital with severe abdominal and back pain. Abdominal CT revealed a gas-containing retroperitoneal abscess surrounded by the duodenal bulb and anterior part of the right kidney. EGD revealed an active ulcer in the duodenal bulb. Furthermore, a slit-shaped excavation of the ulcer floor (A) and retroperitoneal leakage of contrast medium (B) were detected. Therefore, a perforated duodenal ulcer with a retroperitoneal abscess was diagnosed. The perforation was managed conservatively in consideration of the patient’s poor general condition.


    Date de mise en ligne : Mercredi 27 juillet 2016
    Tae Jun Kim, Hyuk Lee, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Kyoung-Mee Kim, Min-Ji Kim, Kyunga Kim, Poong-Lyul Rhee, Jae J. Kim
    One-dimensional and 2-dimensional tumor size measurement for prediction of lymph node metastasis in differentiated early gastric cancer with minute submucosal invasion
    Differentiated minute submucosal cancers measuring ≤3 cm that exhibit no lymphovascular invasion are considered eligible for endoscopic resection; however, the ≤3-cm criterion remains debatable. The aim of this study was to verify the optimal tumor size cutoff for endoscopic resection eligibility, and to determine whether 2-dimensional tumor size measurement would be more accurate for this purpose.


    Date de mise en ligne : Mercredi 27 juillet 2016
    Ihab I. El Hajj, Brian C. Brauer, Sachin Wani, Norio Fukami, Augustin R. Attwell, Raj J. Shah
    Role of per-oral pancreatoscopy in the evaluation of suspected pancreatic duct neoplasia: a 13-year U.S. single-center experience
    The role of per-oral pancreatoscopy (POP) in the evaluation of occult pancreatic duct (PD) lesions remains limited to case series. The aim of this study was to evaluate the ability of POP to differentiate malignant from benign diseases of the PD.


    Date de mise en ligne : Dimanche 24 juillet 2016
    Satoshi Kinoshita, Toshihiro Nishizawa, Tadakazu Hisamatsu, Takanori Kanai, Naohisa Yahagi
    Polyglycolic acid sheet for closure of esophagobronchial fistula in a patient with Behçet's disease
    Esophagobronchial fistula in Behçet's disease is rare, and this condition is difficult to treat. Here we report successful closure of an esophagobronchial fistula using polyglycolic acid (PGA) sheets and fibrin glue. PGA sheets (Neovail; Gunze, Osaka, Japan) is a suture reinforcement material that is absorbed within 4 to 15 weeks. PGA promotes the formation of granulation tissue.


    Date de mise en ligne : Samedi 23 juillet 2016
    Kyoku Sumimoto, Shinji Tanaka, Kenjiro Shigita, Daiki Hirano, Yuzuru Tamaru, Yuki Ninomiya, Naoki Asayama, Nana Hayashi, Shiro Oka, Koji Arihiro, Masaharu Yoshihara, Kazuaki Chayama
    Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team
    The Japan NBI Expert Team (JNET) was established in 2011 and has proposed a universal narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors. The aim of this study was to evaluate the clinical usefulness of the JNET classification for colorectal lesions.


    Date de mise en ligne : Lundi 18 juillet 2016
    Corlan O. Adebajo, Irving Waxman, Christopher Chapman, Carol Semrad
    Foiled by coils: upper GI bleeding from a rare delayed adverse event of transarterial embolization
    A 99-year-old woman was admitted with presyncope and her second GI bleed. One year earlier, she had experienced a major upper-GI bleed from a large cratered duodenal bulb ulcer with a spurting vessel; attempts at endoscopic hemostasis had failed. Angiography revealed a subcentimeter pseudoanuerysm of her gastroduodenal artery (GDA) just caudal to the endoscopic clips. Her GDA was embolized proximal and distal to the pseudoanuerysm with coils extending to the proximal GDA. At her current admission, she was given an intravenous proton pump inhibitor.


    Date de mise en ligne : Samedi 25 juin 2016
    Eugenia N. Uche-Anya, Ali S. Khan, Christopher D. Packey, Diana Sung, Amrita Sethi
    Gastric pancreatic heterotopia with pancreatic intraepithelial neoplasia
    A 39-year-old man reported a 2-year history of postprandial epigastric pain radiating to his back, with nausea and vomiting. Physical examination revealed mild epigastric tenderness. EGD showed a lobulated, hypoechoic 17-mm × 8-mm submucosal nodule in the gastric greater curvature with no adjacent lymph nodes (A and B). Examination of a biopsy specimen demonstrated pancreatic heterotopia (C). He underwent an endoscopic submucosal dissection, en bloc resection of the lesion, and closure with an endoscopic suture.


    Date de mise en ligne : Samedi 25 juin 2016
    Tomoyuki Ushijima, Yoshinobu Okabe, Yusuke Ishida, Masaru Fukahori, Takuji Torimura
    A case of intragastric wall abscess developing after EUS-FNA in a patient with pancreatic body cancer
    The patient, a 71-year-old man presenting with weight loss, was referred to our hospital with a 41-mm tumor of the pancreatic body as shown by CT (A) and bilateral lung nodules. EUS-FNA with a 22G needle revealed cancer cells with necrotic material, and we made a diagnosis of pancreatic cancer. Systemic chemotherapy with gemcitabine was started 14 days after the EUS-FNA; however, the patient experienced epigastric pain and a high fever. Blood examination revealed elevated levels of inflammatory reactants (white blood cell count 14,900/μL, serum C-reactive protein 16.73 mg/dL), and abdominal CT revealed multilocular cystic lesions extending from the ventral aspect of the pancreatic tumor to the gastric wall, surrounded by irregular fat tissue (B).


    Date de mise en ligne : Mercredi 22 juin 2016
    Masaya Iwamuro, Takehiro Tanaka, Haruo Urata, Katsuhiko Kimoto, Hiroyuki Okada
    Lanthanum phosphate deposition in the duodenum
    A 71-year-old Japanese man on hemodialysis for chronic renal failure underwent EGD screening. He had been taking lanthanum carbonate for 6 years to treat hyperphosphatemia. EGD showed diffuse deposition of white microgranules in the gastric body (A). In addition, white villi were observed in the duodenal second portion (B). Histologic examination of the duodenal biopsy specimen from the duodenal mucosa showed a fine, amorphous, eosinophilic material (C) that was also seen in the gastric mucosa. A diagnosis of lanthanum phosphate deposition in the duodenal and gastric mucosa was made after analysis by scanning electron microscopy and elemental mapping showing the colocation of lanthanum and phosphate (D).


    Date de mise en ligne : Samedi 18 juin 2016
    Imad Elkhatib, Natasha Shah, Thomas J. Savides
    Neuroma of the bile duct mimicking cholangiocarcinoma
    A 75-year-old woman presented with a history of right upper-quadrant and epigastric pain for several months. Her history was notable for cholecystectomy for gallstones and ERCP with sphincterotomy for choledocholithiasis several decades previously. MRCP revealed a 14-mm common bile duct with a 5-mm filling defect within the distal duct (A). EUS revealed a 7-mm hypoechoic well-defined nodule in the distal common bile duct, without shadowing, consistent with a soft-tissue lesion (B). The bile duct was 14-mm upstream of the lesion.


    Date de mise en ligne : Samedi 18 juin 2016
    Viviana Parra, Fanny Acero, Eligio Alvarez, Diego Mauricio Aponte, Luis Carlos Sabbagh
    A case mucinous cystic neoplasm from a gastric ectopic pancreas
    The ectopic pancreas is a relatively common phenomenon. These lesions are usually asymptomatic and discovered incidentally during endoscopy, surgery, or autopsy. Mucinous cystic neoplasm (MCN) is a mucin-producing and septated cyst-forming epithelial neoplasia of the pancreas that does not communicate with the pancreatic ductal system. MCN is a cystic neoplasm with a malignant potential. We report the first case of MCN originating from the antrum ectopic pancreas.


    Date de mise en ligne : Samedi 18 juin 2016
    Jae Hyung Lee, Hoon Jai Chun, Bora Keum, Eun Sun Kim, Yoon Tae Jeen
    A case of esophageal hemangioma treated with endoscopic injection sclerotherapy
    An 87-year-old woman presented with a 1-month history of dysphagia. She underwent an endoscopy, which showed a pale-bluish and engorged submucosal tumor obstructing the mid to lower esophagus (A). EUS showed a hypoechoic mass with numerous irregular anechoic spaces within the muscularis mucosa layer (B). Biopsy sampling was performed, and the histopathologic findings showed a vascular lumen with irregular dilatation below the muscularis mucosa, suggesting esophageal cavernous hemangioma. Immunohistochemistry (CD31 and D2-40) was performed later, which confirmed the diagnosis.


    Date de mise en ligne : Vendredi 17 juin 2016
    Jun Fang, Shu-Ling Wang, Hong-Yu Fu, Zhao-Shen Li, Yu Bai
    Impact of gum chewing on the quality of bowel preparation for colonoscopy: an endoscopist-blinded, randomized controlled trial
    Gum chewing can accelerate motility in the GI tract; clinical studies suggested gum chewing can reduce postoperative ileus. However, no trial has investigated the effect of gum chewing on bowel preparation for colonoscopy in addition to polyethylene glycol (PEG). The objective of this study was to investigate whether gum chewing before colonoscopy can increase the quality of bowel preparation.


    Date de mise en ligne : Mardi 14 juin 2016
    Takeshi Tsujino, Yuxin Lu, Kenneth J. Chang
    Treatment of post-EMR duodenal adenoma: a case of unusual recurrence and novel approach
    A 65-year-old man underwent EMR of a 3-cm duodenal polyp. Piecemeal EMR was performed, which was complicated by a perforation, but was successfully closed using the over-the-scope clip system (A). The patient remained asymptomatic and recovered uneventfully. Pathology showed tubular adenoma. Biopsy specimens from the post-EMR site at 4, 8, 12, and 24 months after the initial EMR were all negative for adenoma. EGD at 3 years after the initial EMR, however, demonstrated granulomatous growth around the clip, and biopsy specimens revealed tubulovillous adenoma with low-grade dysplasia.


    Date de mise en ligne : Samedi 11 juin 2016
    Sho Sasaki, Jun Nishikawa, Atsushi Goto, Takeshi Okamoto, Isao Sakaida
    Papillary adenocarcinoma with tentacular processes (with video)
    An 83-year-old man with diabetes mellitus and hypertension presented with a complaint of belching. EGD revealed a polypoid lesion, 10 mm in diameter (A) (Video 1, available online at www.giejournal.org), with tentacular processes on the greater curvature of the gastric body. After the introduction of water into the stomach, each process floated up and clearly separated (B). This lesion appeared just like a sea anemone undulating in the water. Magnifying endoscopy with narrow-band imaging (M-NBI) revealed that each process was lined with white marginal crypt epithelium and contained irregular microvessels that varied in caliber (C).


    Date de mise en ligne : Samedi 11 juin 2016
    Malay Sharma, Piyush Somani, Amol Patil, Avinash Kumar, Charu Shastri
    EUS of solitary rectal ulcer syndrome
    A 55-year-old woman presented with rectal bleeding and straining at stool for 5 months. Sigmoidoscopy showed a large ulceration in the anterior rectal mucosa approximately 7 cm above the anal verge (A). A biopsy specimen was taken, and linear endoscopic ultrasonography (EUS) of the rectum was performed to rule out rectal cancer. EUS showed thick, hyperechoic submucosa and thick muscularis propria in the area of ulceration. It revealed a transition zone where the first interface layer and the muscularis mucosae disappeared and the submucosa gradually became thicker (B).


    Date de mise en ligne : Mercredi 11 mai 2016
    Jun Liong Chin, Subhasish Sengupta, Martina M. Morrin, Frank E. Murray, Stephen E. Patchett
    Common bile duct duplication: double bile ducts, double trouble
    A 43-year-old woman presented with 3 episodes of intermittent severe epigastric discomfort, associated with chills and rigors, in the previous 3 weeks. An abdominal examination revealed mild tenderness in the epigastrium. Her liver blood tests showed predominant cholestasis, with raised alkaline phosphatase 201 IU/L and γ-glutamyltransferase 552 IU/L but normal bilirubin. Her C-reactive protein was raised at 74.9 mg/L. The result of her gastroscopy was normal, but abdominal US showed grossly dilated bile ducts with at least 2 stones.


    Date de mise en ligne : Mercredi 11 mai 2016
    Rintaro Hashimoto, Hidetaka Hamamoto, Yuko Omori, Tokuma Tanuma
    Early gastric cancer on submucosal heterotopic gastric glands
    A 77-year-old man came to our hospital to investigate the cause of his anemia. EGD revealed a submucosal tumor–like elevated lesion 20 mm in diameter, with a central depression in the lesser curvature of the gastric antrum, and a gastric ulcer scar on the posterior wall (A). The lesion was covered with hyperemic mucosa. With magnifying narrow-band imaging endoscopy, the central depression showed an irregular microsurface pattern (B). Biopsy and examination of the biopsy specimen revealed a well-differentiated adenocarcinoma.


    Date de mise en ligne : Mardi 10 mai 2016
    Eduardo Couchonnal, Jérôme Rivory, Sabine Roman, Thierry Ponchon, Mathieu Pioche
    EUS-guided per-oral endoscopic myotomy to treat an achalasia with relapse after Heller's myotomy
    A 76-year-old man underwent Heller’s myotomy with Dor fundoplication for achalasia 12 years ago. He was referred for a progressive recurrence (12 months' duration) of dysphagia with an Eckardt score of 9. Barium transit showed esophageal dilation and a delayed passage through the cardia. Manometry was not feasible because of an extremely sealed lower sphincter that prevented probe passage. An EUS examination was performed to assess the length and position of the previous myotomy and also to eliminate other etiologies like tumor infiltration.


    Date de mise en ligne : Jeudi 05 mai 2016
    Takashi Kanesaka, Noriya Uedo, Koji Higashino, Yoji Takeuchi, Ryu Ishihara
    Traction-assisted endoscopic submucosal dissection of a rectal adenoma located on the anastomotic suture line
    An 80-year-old woman, who had undergone surgery for rectal cancer when in her sixties, was found on colonoscopy to have a 3-cm superficial elevated tumor in her rectum (A). The lesion was located on the anastomotic suture line. Because severe fibrosis prevented EMR, the patient underwent endoscopic submucosal dissection using the clip-with-line technique. After circumferential mucosal incision with a Flushknife BT (DK2618JB15; Fujifilm Medical, Tokyo, Japan), the colonoscope was withdrawn outside the rectum.


    Date de mise en ligne : Lundi 18 avril 2016
    Takeshi Ogura, Wataru Takagi, Shinya Fukunishi, Kazuhide Higuchi, Yoshitaka Kurisu
    Anterior mediastinum tumor diagnosed by EUS-guided FNA from the hypopharynx
    EUS-guided FNA is an established diagnostic method. However, if a tumor is present around the anterior mediastinum, EUS-FNA may be contraindicated because the EUS endoscope is not in the esophagus. Here, we report for the first time that an anterior mediastinum tumor can be diagnosed by EUS-FNA from the hypopharynx.


    Date de mise en ligne : Vendredi 15 avril 2016
    Andrea Anderloni, Alessandro Fugazza, Milena Di Leo, Serena Battista, Alessandro Repici
    A case of cystic duct carcinoma successfully diagnosed with a novel digital cholangioscope
    An 83-year-old man was admitted to our institution because of jaundice and abdominal pain. Magnetic resonance imaging demonstrated dilatation of the proximal common bile duct (CBD) and of the intrahepatic biliary ducts, with an obstacle at the insertion of the cystic duct (A). The subsequent EUS revealed a hypoechoic lesion 7 mm in diameter with irregular margins in the cystic duct (B). FNA was performed through the duodenal bulb with a 25-gauge needle. Although 3 passes were made (rapid on-site evaluation was not available) to obtain macroscopic core tissue, the results of the final cytologic examination were inconclusive.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Information for readers


    Date de mise en ligne : Jeudi 01 janvier 1970
    In upcoming issues...


    Date de mise en ligne : Jeudi 01 janvier 1970
    ASGE update


    Date de mise en ligne : Jeudi 01 janvier 1970
    Focus on...


    Date de mise en ligne : Jeudi 01 janvier 1970
    Editors


    Date de mise en ligne : Jeudi 01 janvier 1970
    Contents


    Date de mise en ligne : Jeudi 01 janvier 1970
    Lyz Bezerra Silva, Manoel Galvão Neto, João Caetano Marchesini, Eduardo S. N. Godoy, Josemberg Campos
    Sleeve gastrectomy leak: endoscopic management through a customized long bariatric stent
    A 28-year-old woman, body mass index 35 kg/m2, underwent laparoscopic sleeve gastrectomy, without drain placement. Twelve days later, she experienced abdominal pain with radiation to her left shoulder, fever, and leukocytosis. The patient was admitted with a clinical diagnosis of gastric leak. Endoscopy showed a leak orifice below the gastroesophageal junction (GEJ), allowing passage to a perigastric cavity, with a small amount of purulent fluid and debris (Figs. 1A and B). This cavity was endoscopically washed with saline solution until the return of fluid was clear.


    Date de mise en ligne : Jeudi 01 janvier 1970
    James Buxbaum, Karthik Ravi, William Ross, Brian Weston, Prasad G. Iyer, Amit Rastogi, Michael B. Wallace
    Continuing Medical Education Exam: April 2017


    Date de mise en ligne : Jeudi 01 janvier 1970
    Erratum
    The American Society for Gastrointestinal Endoscopy (ASGE) Technology Committee’s recently published Status Evaluation Report entitled “Automated endoscope reprocessors” (Gastrointest Endosc 2016;84:885-92) listed the automated endoscope reprocessors (AERs) that have been U.S. Food and Drug Administration (FDA)-cleared for use in Table 2.1 This table inadvertently failed to include the Custom Ultrasonics (Ivyland, PA) System 83 Plus, which is FDA-cleared for reprocessing flexible endoscopes other than duodenoscopes.


    Date de mise en ligne : Jeudi 01 janvier 1970
    David G. Hewett, Shinichiro Sakata
    Classifications for optical diagnosis of colorectal lesions: not 2B with JNET
    Optical diagnosis of colorectal lesions with image-enhanced endoscopy is becoming progressively established in Western colonoscopy practice. It is the cornerstone of 2 management strategies for diminutive colorectal polyps proposed by the American Society for Gastrointestinal Endoscopy (ASGE): “resect and discard,” in which diminutive adenomas are identified, resected, and discarded without pathologic confirmation; and “diagnose and leave,” in which hyperplastic polyps identified in the rectosigmoid colon are left without resection.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Priyanka Kanth, N. Jewel Samadder, James DiSario
    Duodenal adenomas in sporadic and familial adenomatous polyposis patients: Birds of a feather?
    Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited condition caused by mutation in the APC gene and is characterized by hundreds to thousands of adenomatous colorectal polyps.1 Affected persons have a lifetime risk for colorectal cancer of up to 100% without colectomy. Colonoscopy is recommended as early as age 10 years with yearly surveillance procedures. Most patients undergo colectomy because of the significant polyp burden.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Amit Maydeo, Vinay Dhir
    Third-space endoscopy: stretching the limits
    Gastrointestinal endoscopy was invented and traditionally practiced over the past 60-odd years for visualization of the gut lumen. Since its invention, the fear most dreaded by GI endoscopists has been inadvertent injury of the gut wall, leading to a full-thickness perforation. If it occurs, this adverse event has given sleepless nights to even the most experienced endoscopists. GI endoscopy has, however, metamorphosed rapidly over the past few decades from a purely diagnostic procedure into a powerful therapeutic tool.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Silvio W. de Melo, Timothy Woodward
    Addressing disparities in the African-American community: one size does not fit all!
    Over the past several years, attention has finally been paid to issues of health inequities in the United States. A refocusing, in light of current disparities seen in the health of minorities, has been particularly germane regarding GI malignancies in the African-American community. Reductions in colorectal cancer (CRC) have been strikingly much slower among African Americans, who continue to have the highest rate of mortality and lowest survival when compared with all other racial groups.1 Much of the dramatic lowering of CRC incidence and mortality in the general population can be attributed to successful CRC screening, particularly colonoscopy.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Alejandro L. Suarez, Gregory A. Coté
    Can we preserve sphincter of Oddi function by avoiding sphincterotomy? Do we want to?
    Durable endoscopic treatment of choledocholithiasis requires the extraction of gallstones through the sphincter of Oddi muscle complex. With or without stone fragmentation, this maneuver requires adequate expansion of the ampullary and biliary components of the sphincter of Oddi through sphincterotomy, balloon orifice dilation, or both. In the approach to a patient with choledocholithiasis, the prevailing concern is to remove the stones completely and with as little risk and need for reintervention as possible.


    Date de mise en ligne : Jeudi 01 janvier 1970
    David L. Carr-Locke
    Endoscopic papillectomy for adenoma: To inject or not to inject? That is no longer the question
    In our world of procedures, many endoscopists, including myself, hold beliefs and opinions, often based on personal experience, that are not necessarily substantiated by evidence or even a logical approach to a particular disease state or endoscopic challenge. This is not surprising because, despite our scientific best intentions, there can never be observational or randomized studies on every subtle variation in endoscopic technique or every accessory. Hence the teachings of staunch advocates for a particular type of knife for endoscopic submucosal dissection, a particular modality for hemostasis, a particular method of cannulation at ERCP, a particular guidewire for access or stent insertion, use of particular stents in certain situations, and so on.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Barham Abu Dayyeh
    The hunger games: lessons from the past to shape the future
    It is now evident that bariatric and metabolic surgical interventions offer more efficacious and durable weight loss than nonsurgical approaches.1 This efficacy is mediated by multiple anatomic manipulations to the stomach and small intestines resulting in physiologic alterations in gut neuroendocrine signaling, GI motility, autonomic nervous system signaling, bile acid production and absorption, and alterations in gut microbiota leading to a decrease in body weight and adiposity with improvement in the metabolic and mechanical consequences of obesity.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Yuyong Tan, Deliang Liu, Jirong Huo
    Early adverse events of per-oral endoscopic myotomy: the risk factors
    We have read with great interest the article by Werner et al,1 in which they suggested a classification of adverse events (AEs) for per-oral endoscopic myotomy (POEM) and found that the incidence is low, especially for severe AEs. They also noticed that rates of AEs were not significantly different among age, sex distribution, pretreatment, myotomy length, and other factors, using univariate analysis. However, univariate analysis alone is not powerful enough to explore the risk factors, and it would be better if multivariate analysis or Cox proportional hazard model was used for risk factors of AEs, especially severe AEs, so that endoscopists who are performing or going to perform POEM could pay attention to these factors and try to reduce or prevent these AEs.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Eduardo Rodrigues-Pinto, Pedro Pereira, Guilherme Macedo
    Benign esophageal strictures: rule of 3 in esophageal dilation does not need to be a rule
    We read with great interest the article in Gastrointestinal Endoscopy by Grooteman et al1 on the nonadherence to the rule of 3 not increasing the risk of adverse events in esophageal dilation. The rule of 3, theoretically applicable to bougienage alone, was intended to preclude overaggressive dilation. Major adverse events occurred in 1% of 2216 dilation sessions (bougie or balloon dilations), with 0.5% perforations. Nonadherence to the rule of 3 occurred in 13% of bougie dilations. However, dilation to more than 3 mm in 1 session was not associated with more adverse events.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Yi Qin, Magnus Halland
    Esophageal self-dilations as a treatment for refractory benign esophageal strictures
    It was with great interest that we read the study by Repici et al1 on refractory benign esophageal strictures (RBES) and the accompanying editorial by Dr Siersema.2 This study should be commended for reporting a long-term follow-up in RBES treated with endoscopic dilation, self-expandable metallic stents, biodegradable stents, and steroid injections. The study was also comprehensive in analyzing the treatment effect on strictures that differ in location, length, and cause. Ultimately, the study found only a 31.4% rate of clinical resolution for patients with RBES; patients treated with endoprostheses had even a lower rate of successful outcome.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Quan-Lin Li, Ping-Hong Zhou
    Filling the gap: safety of per-oral endoscopic myotomy attested by evidence
    Seven years after its initial application, per-oral endoscopic myotomy (POEM) can hardly still be described as an experimental procedure for the treatment of achalasia. As of July 31, 2016, a PubMed search on POEM returned 275 publications, a rather extraordinary figure for a procedure developed for a rare disease.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Shou-jiang Tang
    Zipper clip closure of colonoscopic perforations
    This author read with great interest the article by Kantsevoy et al1 on endoscopic management of colonic perforations: closure by clips versus suturing. In this retrospective study, primary closure of a colonic perforation was performed with endoscopic through-the-scope (TTS) clips in 5 patients and sutured with an endoscopic suturing device in 16 patients. All 5 patients after EMR with cecal perforation (mean size, 3.4 ± 2.1 mm; range 3-5 mm) after clip closure had worsening of abdominal pain and required laparoscopy (4 patients) or rescue colonoscopy with endoscopic suturing closure (1 patient).