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Mise à jour le : 28-05-2017




Les derniers abstracts de la revue Gastrointestinal Endoscopy :


    Date de mise en ligne : Samedi 27 mai 2017
    Yoshinobu Okabe, Tomoyuki Ushijima, Masafumi Yasunaga, Yutarou Mihara, Takuji Torimura
    A rare case of sarcoidosis in accessory spleen


    Date de mise en ligne : Vendredi 26 mai 2017
    Andrea Parodi, Geoffroy Vanbiervliet, Cesare Hassan, Xavier Hebuterne, Antonella De Ceglie, Rosa Angela Filiberti, Cristano Spada, Massimo Conio
    Colon Capsule to Screen for Colorectal Neoplasia in Subjects with a Family History of Colorectal Cancer
    Colon capsule endoscopy (CCE) has been recognized as an alternative for colorectal cancer (CRC) screening in average risk subjects. To prospectively assess the accuracy of CCE as a screening tool in first-degree relatives (FDRs) of subjects with CRC using optical colonoscopy (OC) with segmental unblinding as reference standard.


    Date de mise en ligne : Vendredi 26 mai 2017
    Aymeric Becq, Gabriel Rahmi, Guillaume Perrod, Christophe Cellier
    Hemorrhagic angiodysplasia of the digestive tract: pathogenesis, diagnosis, and management
    Gastrointestinal angiodysplasia (GIA) is an acquired vascular superficial lesion, which presents typically as a bright red, irregular, round-shaped, slightly elevated lesion. GIAs are often seen in patients over 60 years of age and are mostly located in the colon (cecum and ascending).The cause and mechanisms of GIA have yet to be completely understood. Small-bowel GIAs are often diagnosed in the setting of obscure gastrointestinal bleeding (OGIB). In some cases, GIAs are associated with aortic stenosis, Von Willebrand’s disease, chronic renal disease, and liver disease.


    Date de mise en ligne : Vendredi 26 mai 2017
    Daniela G. Vinsard, Mark E. Stark, Jason T. Lewis, Ming-Hsi Wang
    Nonsteroidal Anti-Inflammatory Drug-Induced Protein-Losing Enteropathy: A Great Masquerade of Crohn’s Disease


    Date de mise en ligne : Mercredi 24 mai 2017
    Michelle J. Alfa, Maira M. Ribeiro, Cristiana da Costa Luciano, Rodrigo Franca, Nancy Olson, Pat DeGagne, Harminder Singh
    A novel polytetrafluoroethylene-channel model, which simulates low levels of culturable bacteria in build-up biofilm after repeated endoscope reprocessing
    Clinical studies have shown variable culture results from flexible endoscope channels possibly due to low levels of bacteria that are difficult to extract. The aim of this study was to develop a simulated-use buildup biofilm (BBF) model that mimics low levels of viable bacteria after repeated rounds of aldehyde fixation and accumulation.


    Date de mise en ligne : Mercredi 24 mai 2017
    Jose Nieto, Huda Khaleel, Youssef Challita, Melissa Jimenez, Todd H. Baron, Laura Walters, Kelli Hathaway, Ketul Patel, Ali Lankarani, Michael Herman, David Holloman, Sammy Saab
    EUS-guided fine-needle core liver biopsy using a novel 19G needle with modified one pass, one actuation wet suction technique
    EUS-guided fine-needle core biopsy is a safe and effective technique for diagnosis of focal liver lesions. However, data are limited in its role in parenchymal disease. We evaluated the utility of EUS-guided parenchymal liver biopsies (EUS-LB) with a modified one pass wet suction technique (EUS-MLB) in patients with unexplained increase in liver associated tests.


    Date de mise en ligne : Mardi 23 mai 2017
    Sajan Jiv Singh Nagpal, Dhruvika Mukhija, Madhusudhan Sanaka, Rocio Lopez, Carol A. Burke
    Metachronous colon polyps in younger versus older adults: a case-control study
    The incidence of colorectal cancer (CRC) in the United States has decreased substantially in individuals aged 50 and older. Contrariwise, it is increasing in young adults. The polyp characteristics on baseline and follow-up colonoscopy in young adults are not well characterized. We describe the polyp characteristics on baseline and follow-up colonoscopy in adults < 40 years and determined factors associated with the occurrence of metachronous, advanced neoplasia or high risk (HR) polyp features.


    Date de mise en ligne : Mercredi 17 mai 2017
    Marco Bassi, Carmelo Luigiano, Stefania Ghersi, Carlo Fabbri, Giulia Gibiino, Lucio Balzani, Giuseppe Iabichino, Alberto Tringali, Raffaele Manta, Massimiliano Mutignani, Vincenzo Cennamo
    A multicenter randomized trial comparing the use of touch versus no-touch guidewire technique for deep biliary cannulation: the TNT study
    There are 2 techniques described for selective bile duct guidewire cannulation, the touch (T) technique (engaging the papilla with a sphincterotome and then advancing the guidewire) and the no-touch (NT) technique (engaging the papilla only with the guidewire). The aim of this prospective, multicenter randomized study was to compare the outcomes of the 2 guidewire cannulation techniques.


    Date de mise en ligne : Mercredi 10 mai 2017
    Yoshihito Tanaka, Hiro-o Yamano, Eiichiro Yamamoto, Hiro-o Matushita, Hironori Aoki, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Michiko Nakaoka, Yuko Yoshida, Makoto Eizuka, Tamotsu Sugai, Hiromu Suzuki, Hiroshi Nakase
    Endoscopic and Molecular Characterization of Colorectal Sessile Serrated Adenoma/polyps with Cytological Dysplasia
    Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with BRAF mutation and the CpG island methylator phenotype (CIMP), develop cytological dysplasia (CD) during the progression of colorectal tumorigenesis. In the present study, we aimed to clarify the endoscopic and molecular signatures of SSA/Ps, with and without CD.


    Date de mise en ligne : Mercredi 10 mai 2017
    Navin L. Kumar, Guillaume Kugener, Molly L. Perencevich, John R. Saltzman
    The SAFE-T Assessment Tool: Derivation and Validation of a Web-based Application for Point-of-care Evaluation of Gastroenterology Fellow Performance in Colonoscopy
    Attending assessment is a critical part of endoscopic education for gastroenterology fellows. The aim of this study was to develop and validate a concise assessment tool to evaluate real-time fellow performance in colonoscopy administered via a web-based application.


    Date de mise en ligne : Mercredi 10 mai 2017
    Eisuke Ueshima, Mark Schattner, Robin Mendelsohn, Hans Gerdes, Sebastien Monette, Haruyuki Takaki, Jeremy C. Durack, Stephen B. Solomon, Govindarajan Srimathveeravalli
    Transmural Ablation of the Normal Porcine Common Bile Duct with Catheter-Directed Irreversible Electroporation is Feasible and Does Not Impact Duct Patency


    Date de mise en ligne : Mardi 09 mai 2017
    Gene K. Ma, David A. Pegues, Michael L. Kochman, Kevin Alby, Neil O. Fishman, Marianne Saunders, Carolyn Grous, Daniel T. Dempsey, Gregory G. Ginsberg
    Implementation of a systematic culturing program to monitor efficacy of endoscope reprocessing: outcomes and costs
    In 2015, the U.S. Food and Drug Administration and Centers for Disease Control and Prevention (CDC) issued guidance for duodenoscope culturing and reprocessing in response to outbreaks of carbapenem-resistant Enterobacteriaceae (CRE) duodenoscope-related infections. Based on this guidance, we implemented best practices for reprocessing and developed a systematic process for culturing endoscopes with elevator levers. The aim of this study is to report the outcomes and direct costs of this program.


    Date de mise en ligne : Jeudi 04 mai 2017
    Andreas Oberbach, Nadine Schlichting, Marco Heinrich, Yvonne Kullnick, Ulf Retschlag, Stefanie Lehman, Mouen A. Khashab, Anthony N. Kalloo, Vivek Kumbhari
    Gastric Mucosal Devitalization Reduces Adiposity and Improves Lipid and Glucose Metabolism in Obese Rats
    The gastric mucosa is an endocrine organ that regulates satiation pathways by expression of orexigenic and anorexigenic hormones. Vertical sleeve gastrectomy (VSG), excludes gastric mucosa and reduces gastric volume. Our study aims to investigate the independent effects of altering gastric mucosa on obesity and its related comorbidities.


    Date de mise en ligne : Jeudi 04 mai 2017
    Tae Hoon Lee, Tae Hyeon Kim, Jong Ho Moon, Sang Hyub Lee, Hyun Jong Choi, Young Hwangbo, Jong Jin Hyun, Jun-Ho Choi, Seok Jeong, Jong Hyeok Kim, Do Hyun Park, Joung-Ho Han, Sang-Heum Park
    Bilateral versus unilateral placement of metal stents for inoperable high-grade malignant hilar biliary strictures: a multicenter, prospective, randomized study (with video)
    The efficacy of palliative biliary drainage using bilateral or unilateral self-expandable metal stents (SEMSs) for a malignant hilar biliary stricture (MHS) remains controversial. This prospective, randomized, multicenter study investigated whether bilateral drainage using SEMSs is superior to unilateral drainage in patients with inoperable MHS.


    Date de mise en ligne : Mercredi 03 mai 2017
    Froukje B. van Hoeij, Fraukje A. Ponds, Yuki Werner, Joel M. Sternbach, Paul Fockens, Barbara A. Bastiaansen, André JPM. Smout, John E. Pandolfino, Thomas Rösch, Albert J. Bredenoord
    Management of recurrent symptoms after per-oral endoscopic myotomy in achalasia
    Per-oral endoscopic myotomy (POEM) has been rapidly gaining ground as a treatment for achalasia. Although POEM is a safe and effective treatment, a subset of patients has persistent or recurrent symptoms after POEM. This study aimed to examine the efficacy of different retreatments after failed POEM.


    Date de mise en ligne : Mercredi 03 mai 2017
    Douglas K. Rex, Prasanna Ponugoti, Cynthia S. Johnson, Lisa Kittner, Randy Yanda
    Neoplasia at 10-year follow-up screening colonoscopy in a private U.S. practice: comparison of yield to first-time examinations
    Prior studies assessing the yield of a second screening colonoscopy performed 10 years after an initial negative screening colonoscopy did not include a control group of persons undergoing their first screening colonoscopy during the same time interval.Our aim was to describe the incidence of neoplasia at a second screening colonoscopy (performed at least 8 years after the first colonoscopy) in average risk individuals and compare it with the yield of first screening examinations performed during the same time interval.


    Date de mise en ligne : Mercredi 03 mai 2017
    Yun Duk Jung, Woo Chul Chung, Yeon-Ji Kim, Kyong-Hwa Jun, Hyung-Min Chin
    Gastric Neuroendocrine Tumor Mimicking Early Gastric Cancer


    Date de mise en ligne : Mercredi 03 mai 2017
    Masanori Kobayashi, Ou Yamaguchi, Koji Nagata, Kouichi Nonaka, Shomei Ryozawa
    Acute hemorrhagic gastritis after nivolumab treatment


    Date de mise en ligne : Mercredi 03 mai 2017
    Barham K. Abu Dayyeh, Saurabh Mukewar, Shounak Majumder, Raja Zaghlol, Eric J. Vargas Valls, Fateh Bazerbachi, Michael J. Levy, Todd H. Baron, Christopher J. Gostout, Bret T. Petersen, John Martin, Ferga C. Gleeson, Randall K. Pearson, Suresh T. Chari, Santhi S. Vege, Mark D. Topazian
    Large-Caliber Metal Stents Versus Plastic Stents for the Management of Pancreatic Walled-Off Necrosis
    Symptomatic pancreatic walled-off necrosis (WON) may be managed by endoscopic transmural drainage and endoscopic transmural necrosectomy, with stent placement at endoscopic drainage sites. The optimal stent choice is yet to be determined. We compared outcomes after endoscopic management of WON using either large-caliber fully covered, self-expandable metal stents (LC-SEMSs) or double-pigtail plastic stents (DPPSs).


    Date de mise en ligne : Mardi 02 mai 2017
    Timothy D. Imler, Stuart Sherman, Thomas F. Imperiale, Huiping Xu, Fangqian Ouyang, Christopher Beesley, Charity Hilton, Gregory A. Coté
    Provider-specific quality measurement for ERCP using natural language processing
    Natural language processing (NLP) is an information retrieval technique that has been shown to accurately identify quality measures for colonoscopy. There are no systematic methods by which to track adherence to quality measures for ERCP, the highest risk endoscopic procedure widely used in practice.


    Date de mise en ligne : Vendredi 28 avril 2017
    Michael Dougherty, Thomas M. Runge, Swathi Eluri, Evan S. Dellon
    Esophageal dilation with either bougie or balloon technique as a treatment for eosinophilic esophagitis: a systematic review and meta-analysis
    Esophageal dilation is a now recognized to be an important therapeutic modality in eosinophilic esophagitis (EoE). We aimed to evaluate the safety of esophageal dilation in EoE, especially regarding perforation risk, and to examine perforation risk by dilator type.


    Date de mise en ligne : Vendredi 28 avril 2017
    Carlos Robles-Medranda, Miguel Puga-Tejada, Jesenia Ospina, Manuel Valero, Hannah Pitanga Lukashok
    Over-the-scope clip in the management of fibrotic esophageal variceal bleeding (with video)


    Date de mise en ligne : Vendredi 28 avril 2017
    Eddie Y. Liu, Paul J. Belletrutti
    Isolated esophageal tears from deceleration trauma


    Date de mise en ligne : Mardi 25 avril 2017
    James P. Moriarty, Nilay D. Shah, Joel H. Rubenstein, Christopher H. Blevins, Michele Johnson, David A. Katzka, Kenneth K. Wang, Louis Michel Wongkeesong, David A. Ahlquist, Prasad G. Iyer
    Costs associated with Barrett’s Esophagus Screening in the Community: an Economic Analysis of a Prospective Randomized Controlled Trial of Sedated Versus Hospital Unsedated Versus Mobile Community Unsedated Endoscopy
    Data on the economic impact associated with screening for Barrett’s esophagus (BE) are limited. As part of a comparative effectiveness randomized trial of unsedated transnasal endoscopy (uTNE) and sedated endoscopy (sEGD), we assessed costs associated with BE screening.


    Date de mise en ligne : Mardi 25 avril 2017
    Kamar Belghazi, Frederike G.I. van Vilsteren, Bas L.A.M. Weusten, Sybren L. Meijer, Jacques J.G.H.M. Bergman, Roos E. Pouw
    Long-term Follow-up Results of Stepwise Radical Endoscopic Resection for Barrett’s Esophagus with Early Neoplasia
    Stepwise radical endoscopic resection (SRER) has shown to be effective in eradicating Barrett’s esophagus (BE) and its associated dysplasia. The aim of this study was to assess the long-term durability after successful SRER for early Barrett’s neoplasia.


    Date de mise en ligne : Mardi 25 avril 2017
    Rachel S. van der Post, Jolanda van Dieren, Anna Grelack, Nicoline Hoogerbrugge, Lizet E. van der Kolk, Petur Snaebjornsson, Iris Lansdorp-Vogelaar, J Han van Krieken, Tanya M. Bisseling, Annemieke Cats
    Outcomes of Screening Gastroscopy in First-degree Relatives of Patients Fulfilling Hereditary Diffuse Gastric Cancer Criteria
    The aim of this study was to determine the yield of endoscopic screening in first-degree relatives (FDR) of CDH1-negative hereditary diffuse gastric cancer (HDGC) patients.


    Date de mise en ligne : Mardi 25 avril 2017
    Peter B. Cotton, Qi Pauls, Jamila Keith, Andre Thornhill, Douglas Drossman, April Williams, Valerie Durkalski-Mauldin
    The EPISOD study: long-term outcomes
    The EPISOD (Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction) study randomized subjects with post-cholecystectomy pain, and little or no objective evidence for biliary obstruction, to sphincterotomy or sham intervention. Results at 1 year showed no benefit for the active treatment. We now report the outcomes at up to 5 years.


    Date de mise en ligne : Mardi 25 avril 2017
    Fernanda Prata Martins, Gustavo Andrade De Paulo, MĂŽnica L.C. Contini, Angelo Paulo Ferrari
    Metal versus Plastic Stents for Anastomotic Biliary Strictures after Liver Transplantation: a Randomized Controlled Trial
    biliary anastomotic stricture occurs in 15% to 20% of patients after deceased orthotopic liver transplantation (OLT). Usually treated endoscopically with multiple plastic stents (MPSs), although the use of fully covered self-expandable metal stents (cSEMSs) is emerging. This study aims to compare efficacy and safety of cSEMSs versus MPSs in these patients.


    Date de mise en ligne : Jeudi 20 avril 2017
    Ming Tan, Ove B. Schaffalitzky de Muckadell, Stig B. Laursen
    Association between early ERCP and mortality in patients with acute cholangitis
    Acute cholangitis (AC) is associated with high mortality of up to 10%. The association between timing of ERCP and mortality in AC patients remains unclear. The aim of this study was to investigate if early ERCP within 24 hours was associated with improved survival.


    Date de mise en ligne : Jeudi 20 avril 2017
    Jennifer H. Lai, Gavin Park, Lauren B. Gerson
    Association between Breast Cancer and the Risk of Colorectal Cancer: Systematic Review and Meta-Analysis
    The prior literature has suggested a potential increase in colorectal cancer (CRC) among patients with breast cancer.


    Date de mise en ligne : Jeudi 20 avril 2017
    Luca Elli, Giovanni Casazza, Martina Locatelli, Federica Branchi, Francesca Ferretti, Dario Conte, Mirella Fraquelli
    Use of enteroscopy for the detection of malignant and pre-malignant lesions of the small bowel in complicated celiac disease: a meta-analysis
    Enteroscopy (wireless, wired) is the reference standard for small-bowel (SB) diseases and it has been applied to detect SB malignancies in complicated celiac disease (CD) with heterogeneous results.The aim of this meta-analysis is to obtain a diagnostic yield (DY) by pooling the data of studies that investigated the use of enteroscopy to detect SB adverse events in CD.


    Date de mise en ligne : Mardi 18 avril 2017
    Chen Chen, Christian Stock, Michael Hoffmeister, Hermann Brenner
    Public health impact of colonoscopy use on colorectal cancer mortality in Germany and the United States
    Colonoscopy has been demonstrated to be effective in reducing colorectal cancer (CRC) incidence and mortality, and has been widely used for primary CRC screening in Germany and the United States. We performed a population-based analysis to evaluate and compare the public health impact of recent colonoscopy use on CRC deaths among adults aged 55 to 79 years in Germany and the United States from 2008 to 2011.


    Date de mise en ligne : Mardi 18 avril 2017
    Hee Seung Lee, Sung Bae Kim, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim
    Postoperative adjuvant chemotherapy is associated with a lower incidence of colorectal adenomas in patients with previous colorectal cancer
    The effects of chemotherapeutic agents on the development of colorectal adenomas in patients with previous colorectal cancer (CRC) are not defined. Therefore, we evaluated the potential effect of adjuvant chemotherapy on the incidence of colorectal adenomas in patients with previous CRC.


    Date de mise en ligne : Jeudi 13 avril 2017
    Zacharias P. Tsiamoulos, Ravi Misra, Rajaratanam Rameshshanker, Timothy R. Elliott, Iosif Beintaris, Siwan Thomas-Gibson, Adam Haycock, Noriko Suzuki, Colin Rees, Brian P. Saunders
    Impact of a new distal attachment on colonoscopy performance in an academic screening center
    Distal attachments placed on the colonoscope tip may positively affect performance by assisting insertion and polyp detection. The original Endocuff (ARC Medical Design, Leeds, United Kingdom) appears to improve adenoma detection rate (ADR), but no data assess the performance of the second-generation Endocuff Vision.


    Date de mise en ligne : Lundi 10 avril 2017
    Anne F. Peery, Nicholas J. Shaheen, Katherine S. Cools, Todd H. Baron, Mark Koruda, Joseph A. Galanko, Ian S. Grimm
    Morbidity and mortality after surgery for nonmalignant colorectal polyps
    Despite evidence that most nonmalignant colorectal polyps can be managed endoscopically, a substantial proportion of patients with a nonmalignant colorectal polyp are still sent to surgery. Risks associated with this surgery are not well characterized. We describe 30-day postoperative morbidity and mortality and explore risk factors for adverse events in patients undergoing surgical resection for nonmalignant colorectal polyps.


    Date de mise en ligne : Vendredi 07 avril 2017
    Loren Laine, Stig B. Laursen, Harry R. Dalton, Jing H. Ngu, Michael Schultz, Adrian J. Stanley
    Relationship of time to presentation after onset of upper GI bleeding with patient characteristics and outcomes: a prospective study
    We performed a prospective multi-national study of patients presenting to the emergency department with upper GI bleeding (UGIB) and assessed the relationship of time to presentation after onset of UGIB symptoms with patient characteristics and outcomes.


    Date de mise en ligne : Vendredi 07 avril 2017
    Douglas K. Rex, Cesare Hassan, Michael J. Bourke
    The colonoscopist's guide to vocabulary of colorectal neoplasia: histology, morphology, and management
    Prevention of colorectal cancer by colonoscopy requires effective and safe insertion technique, high level detection of precancerous lesions, and skillful use of curative endoscopic resection techniques. Lesion detection, characterization, use of appropriate resection methods, prediction of cancer at colonoscopy, and management of malignant polyps, all depend on an accurate and complete understanding of an extensive vocabulary describing the histology and morphology of neoplastic colorectal lesions.


    Date de mise en ligne : Vendredi 07 avril 2017
    Benjamin L. Bick, Thomas F. Imperiale, Cynthia S. Johnson, John M. DeWitt
    Endoscopic suturing of esophageal fully covered self-expanding metal stents reduces rates of stent migration
    Endoscopic suturing of fully covered self-expanding metal stents (FC-SEMSs) may prevent migration. The aim of this study was to compare rates of migration between sutured FC-SEMSs (S-FCSEMSs), unsecured FC-SEMSs, and partially covered SEMSs (PC-SEMSs) placed for benign esophageal leaks and strictures.


    Date de mise en ligne : Vendredi 07 avril 2017
    Kavel Visrodia, Yuri Hanada, Kelly M. Pennington, Pritish K. Tosh, Mark D. Topazian, Bret T. Petersen
    Duodenoscope reprocessing surveillance with adenosine triphosphate testing and terminal cultures: a clinical pilot study
    Recent reports of infectious outbreaks linked to duodenoscopes have led to proposals for duodenoscope surveillance culturing, which has inherent limitations. We aimed to assess the feasibility of real-time adenosine triphosphate (ATP) testing after manual cleaning and its ability to predict reprocessing adequacy, as determined by terminal duodenoscope cultures.


    Date de mise en ligne : Vendredi 07 avril 2017
    Nisa Netinatsunton, Jaksin Sottisuporn, Siriboon Attasaranya, Teepawit Witeerungrot, Aroon Siripun, Tanawat Pattarapuntakul, Bancha Ovartlarnporn
    Prospective randomized trial of EUS-assisted ERCP without fluoroscopy versus ERCP in common bile duct stones
    ERCP with stone removal is the standard treatment for common bile duct stones (CBDSs). Radiation exposure is a risk to the endoscopist and patient. EUS-guided ERCP without fluoroscopy (EGEWF) in patients with CBDSs is feasible, but the efficacy and safety compared with ERCP is unknown. We aimed to compare the efficacy and safety of EGEWF with ERCP in CBDS removal.


    Date de mise en ligne : Vendredi 07 avril 2017
    Ye Han, Jintao Guo, Siyu Sun, Weichao Wu, Sheng Wang, Nan Ge, Xiang Liu, Guoxin Wang, Shupeng Wang
    Acellular dermal matrix for esophageal stricture prevention after endoscopic submucosal dissection in a porcine model
    Endoscopic submucosal dissection (ESD) is considered an effective treatment for early esophageal cancer and precancerous lesions. Esophageal stenosis is closely associated with quasi-circumferential ESD. We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane.


    Date de mise en ligne : Jeudi 06 avril 2017
    Sung Yong Han, Gwang Ha Kim
    Collision tumor arising from a gastric duplication cyst
    A 41-year-old woman presented with a gastric subepithelial lesion. Upper endoscopy revealed a 6-cm subepithelial mass with surface erosions at the posterior wall of the upper body of the stomach (A). Endoscopic ultrasonography revealed a homogenous cystic lesion with inner mucus debris and a solid mass in the periphery, which invaded the pancreatic tail (B, arrow). Total gastrectomy and distal pancreatectomy were performed. The cyst was located in the muscularis propria of the stomach (C, arrowhead), and a histopathologic examination showed that the cystic space was lined by columnar or squamous epithelial mucosa.


    Date de mise en ligne : Jeudi 06 avril 2017
    Alberto Arezzo, Roberto Passera, Giacomo Lo Secco, Mauro Verra, Marco Augusto Bonino, Eduardo Targarona, Mario Morino
    Stent as bridge to surgery for left-sided malignant colonic obstruction reduces adverse events and stoma rate compared with emergency surgery: results of a systematic review and meta-analysis of randomized controlled trials
    Twenty years after the first description of the technique, the debate is still open on the role of self-expandable metallic stent (SEMS) placement as a bridge to elective surgery for symptomatic left-sided malignant colonic obstruction. The aim was to compare morbidity rates after colonic stenting bridge to surgery (SBTS) versus emergency surgery (ES) for left-sided malignant obstruction.


    Date de mise en ligne : Jeudi 06 avril 2017
    Yasser Shaib, Lara Hassoun
    Double-lumen duodenum
    A 33-year-old man with a history of Hodgkin lymphoma was seen 92 days after allogenic stem cell transplantation; he presented with a 5-day history of large-volume watery diarrhea. The results of laboratory evaluation and stool studies were noncontributory. Flexible sigmoidoscopy with examination of biopsy specimens revealed mild chronic colitis with no evidence of graft-versus-host disease (GVHD). Nevertheless, the patient was given systemic and nonabsorbable steroid agents. However, he continued to have large-volume diarrhea, worsening anorexia, and malnutrition.


    Date de mise en ligne : Mardi 04 avril 2017
    Antonio D’Antonio, Patrizia Borgheresi, Maria Addesso
    An unexpected adverse event of gastric bypass: giant hyperplastic polyp showing an intramucosal adenocarcinoma
    A 58-year-old woman underwent a gastroscopy for iron deficiency anemia, epigastric pain, outlet obstruction, and abdominal distension. The patient had undergone open gastric bypass 4 years earlier because of morbid obesity. The gastroscopy showed a pedunculated 8-cm polyp with a thick stalk on the anterior wall of the antrum (A). The polyp surface appeared composed of multiple villous-like projections with a smooth surface (B). Examination of repeated biopsy specimens from the polypoid lesion showed a hyperplastic polyp.


    Date de mise en ligne : Mardi 04 avril 2017
    Douglas G. Adler
    Use of a lumen-apposing metal stent to treat pyloric stenosis
    A 77-year-old woman with a 100 pack/year history of tobacco use presented to our center with failure to thrive, weight loss, and intolerance of oral intake. Chest, abdominal, and pelvic CT revealed multiple lung masses and liver metastases. Examination of a biopsy specimen from her lung mass revealed squamous cell carcinoma of the lung. A positron emission tomography scan did not show hypermetabolic activity at the pylorus. An EGD was performed to investigate her eating issues and revealed a high-grade stenosis of her pylorus with an overall benign appearance suggestive of scarring secondary to prior peptic ulcer disease (A).


    Date de mise en ligne : Mardi 04 avril 2017
    Harry D.S. Soar, Muhammad H. Shiwani
    Successful endoscopic removal of a telescopic radio aerial from the stomach
    Ingestion of a foreign body is a common reason for attendance at the emergency department. Each case provides a unique challenge depending on the size, shape, and consistency of the object swallowed. We present a challenging case of a rarely ingested and unusually shaped object: a telescopic radio aerial and the techniques we used to successfully manage it. A 23-year-old woman from a local psychiatric hospital had swallowed a biro pen and a metal telescopic radio aerial that she had broken off from an FM radio.


    Date de mise en ligne : Lundi 03 avril 2017
    Luis F. Lara, Morihito Takita, James S. Burdick, Daniel C. DeMarco, Ronnie R. Pimentel, Tolga Erim, Marlon F. Levy
    A study of the clinical utility of a 20-minute secretin-stimulated endoscopic pancreas function test and performance according to clinical variables
    Direct pancreas juice testing of bicarbonate, lipase, or trypsin after stimulation by secretin or cholecystokinin is used to determine exocrine function, a surrogate for diagnosing chronic pancreatitis (CP). Endoscopic pancreas function tests (ePFTs), where a peak bicarbonate concentration (PBC) ≄80 mEq/L in pancreas juice is considered normal, are now used more frequently. In this ePFT, aspirates start 35 minutes after secretin administration because pancreas output peaks 30 minutes after secretagogue administration.


    Date de mise en ligne : Lundi 03 avril 2017
    Yoon Suk Jung, Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn
    Colorectal cancer screening with the fecal immunochemical test in persons aged 30 to 49 years: focusing on the age for commencing screening
    The fecal immunochemical test (FIT) can be an alternative screening method for colorectal cancer in individuals aged <50 years. However, debate continues concerning the age at which commencing FIT is beneficial.


    Date de mise en ligne : Lundi 03 avril 2017
    Standards of Practice Committee, Ashley L. Faulx, Shivangi Kothari, Ruben D. Acosta, Deepak Agrawal, David H. Bruining, Vinay Chandrasekhara, Mohamad A. Eloubeidi, Robert D. Fanelli, Suryakanth R. Gurudu, Mouen A. Khashab, Jenifer R. Lightdale, V. Raman Muthusamy, Aasma Shaukat, Bashar J. Qumseya, Amy Wang, Sachin B. Wani, Julie Yang, John M. DeWitt
    The role of endoscopy in subepithelial lesions of the GI tract
    This is one of a series of statements discussing the use of GI endoscopy in common clinical situations. The Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy (ASGE) prepared this text. In preparing this guideline, a search of the medical literature was performed by using PubMed. Additional references were obtained from the bibliographies of the identified articles and from recommendations of expert consultants. When little or no data existed from well-designed prospective trials, emphasis was given to results from large series and reports from recognized experts.


    Date de mise en ligne : Samedi 01 avril 2017
    Navin L. Kumar, Brian L. Claggett, Aaron J. Cohen, Jennifer Nayor, John R. Saltzman
    Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding
    An increase in blood urea nitrogen (BUN) at 24 hours is a solitary and significant predictor of mortality in patients with acute pancreatitis, which may predict worse outcomes in the similarly resuscitation-requiring condition of acute nonvariceal upper GI bleeding (UGIB). The aim of our study was to assess whether an increase in BUN at 24 hours is predictive of worse clinical outcomes in acute nonvariceal UGIB.


    Date de mise en ligne : Jeudi 30 mars 2017
    Peter B. Cotton, Derek Feussner, Darin Dufault, Gregory Cote
    A survey of credentialing for ERCP in the United States
    There are limited data measuring the variability in standards used by hospitals for credentialing physicians to ERCP in the United States.


    Date de mise en ligne : Jeudi 30 mars 2017
    Samir C. Grover, Michael A. Scaffidi, Rishad Khan, Ankit Garg, Ahmed Al-Mazroui, Tareq Alomani, Jeffrey J. Yu, Ian S. Plener, Mohamed Al-Awamy, Elaine L. Yong, Maria Cino, Nikila C. Ravindran, Mark Zasowski, Teodor P. Grantcharov, Catharine M. Walsh
    Progressive learning in endoscopy simulation training improves clinical performance: a blinded randomized trial
    A structured comprehensive curriculum (SCC) that uses simulation-based training (SBT) can improve clinical colonoscopy performance. This curriculum may be enhanced through the application of progressive learning, a training strategy centered on incrementally challenging learners. We aimed to determine whether a progressive learning-based curriculum (PLC) would lead to superior clinical performance compared with an SCC.


    Date de mise en ligne : Jeudi 30 mars 2017
    James L. Buxbaum, David Hormozdi, Mario Dinis-Ribeiro, Christianne Lane, Diogo Dias-Silva, Ara Sahakian, Preeth Jayaram, Pedro Pimentel-Nunes, Daniel Shue, Michael Pepper, Daniel Cho, Loren Laine
    Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial
    Gastric intestinal metaplasia (GIM) is a gastric cancer precursor. Narrow-band imaging (NBI) may improve detection of GIM. We compared detection of GIM with high-definition white-light (HD-WL) endoscopy, NBI, and mapping biopsies in a population with increased gastric cancer risk.


    Date de mise en ligne : Mercredi 29 mars 2017
    Enqiang Linghu, Chen Du, Ningli Chai, Huikai Li, Zhiqiang Wang, Yufa Sun, Wei Xu, Xu Guo, Bo Ning, Lihua Sun, Wei Zhang, Xiangdong Wang, Ping Tang, Jia Feng
    A prospective study on the safety and effectiveness of using lauromacrogol for ablation of pancreatic cystic neoplasms with the aid of EUS
    With the development of imaging techniques, the detection rate of pancreatic cystic neoplasms (PCNs) has increased. The surgical morbidity and mortality rates of PCNs are quite high. This study is intended to evaluate the safety and effectiveness of a minimally invasive treatment, EUS-guided PCN ablation with lauromacrogol.


    Date de mise en ligne : Mercredi 29 mars 2017
    Madhav Desai, Andre Sanchez-Yague, Abhishek Choudhary, Asad Pervez, Neil Gupta, Prashanth Vennalaganti, Sreekar Vennelaganti, Alessandro Fugazza, Alessandro Repici, Cesare Hassan, Prateek Sharma
    Impact of cap-assisted colonoscopy on detection of proximal colon adenomas: systematic review and meta-analysis
    Proximal colon adenomas can be missed during routine colonoscopy. Use of a cap or hood on tip of the colonoscope has shown to improve overall adenoma detection with variable rates. However, it has not been systematically evaluated for detection of proximal colon or right-sided adenomas where the cap may have maximum impact on adenoma detection rate (ADR). Our aim was to perform a systematic review and meta-analysis to evaluate the impact of cap-assisted colonoscopy (CC) on right-sided ADRs (r-ADRs) compared with standard colonoscopy (SC).


    Date de mise en ligne : Samedi 25 mars 2017
    R. Sanchez-Ocana, I. Penas-Herrero, F. Santos-Santamarta, C. de la Serna-Higuera, M. Perez-Miranda
    EUS-Guided Removal of a Buried Lumen-Apposing Metal Stent Caused by Delayed Inward Migration after Cyst-Gastrostomy


    Date de mise en ligne : Mercredi 22 mars 2017
    Yuta Koike
    A rare cause of recurrent acute pancreatitis: duodenum intussusception by a fenestrated duodenal web
    A 13-year-old boy presented with a body weight that was low for his age; he had experienced repeated vomiting episodes and acute pancreatitis of an unknown cause since he was 9 years old. When acute pancreatitis developed for the fifth time, CT of the abdomen revealed severe acute pancreatitis with a duodenum-within-duodenum configuration, indicating the second portion of a duodenal intussusception (A). Duodenal intussusception prevented the normal flow of pancreatic enzymes, which may have caused the acute pancreatitis.


    Date de mise en ligne : Mercredi 22 mars 2017
    Mathew Keegan, Rooshdiya Karim, Arthur Kaffes, Payal Saxena
    A welcome diagnosis for painless biliary dilatation (with video)
    A 59-year-old man presented with acute functional decline and painless liver biochemistry derangement: elevation of aspartate aminotransferase 160 IU/L, alanine aminotransferase 71 IU/L, and γ-glutamyl transferase 63 IU/L, with normal levels of bilirubin and alkaline phosphate. A CT scan demonstrated a 10-mm hypodensity at the ampulla of Vater associated with a prominent extrahepatic biliary duct (A). Assessment with a duodenoscope revealed a bulky ampulla. Normal-appearing overlying mucosa was confirmed on histopathologic examination.


    Date de mise en ligne : Mercredi 22 mars 2017
    Sinkeet Ranketi, Michael Mwachiro, Mark Topazian, Stephen Burgert
    Endoscopic treatment of cervical esophageal transluminal bridge
    A 27-year-old woman presented with dysphagia. She had undergone endoscopic dilation of an idiopathic esophageal stricture at 5 years of age, and she had been swallowing well until 1 month before presentation. EGD revealed a mild stricture at 18 cm from the incisors, a midluminal transverse esophageal mucosal bridge at 20 cm (A), and a tight distal stricture at 30 cm, which was serially dilated over a guidewire with the use of Savary dilators of sizes 18F, 21F, and 24F diameter. The endoscope was then able to advance, and no mucosal injuries were noted.


    Date de mise en ligne : Dimanche 19 mars 2017
    Shani Woolard, Paula Adamson, Emad Qayed
    Esophageal fibrous band causing dysphagia in an HIV+ patient
    A 40-year-old man with a history of HIV/AIDS presented with persistent dysphagia. He had undergone multiple upper endoscopies over the previous year because of dysphagia and odynophagia and had been found to have recurrent idiopathic HIV-associated esophageal ulcers, which required dilations and thalidomide administration. The patient then underwent a repeat upper endoscopy, which showed healed esophageal ulcers and a 5-cm-long band of fibrous tissue in the distal esophagus (A). The proximal and distal ends of the band were located 30 cm and 35 cm, respectively, from the incisors.


    Date de mise en ligne : Samedi 18 mars 2017
    Min Min, Yiliang Bi, Yan Liu, Yang Xu
    Extramedullary gastric relapse of acute lymphoblastic leukemia in an adolescent
    A 16-year-old girl who had undergone hemopoietic stem cell transplantation for acute lymphoblastic leukemia (ALL) 2 years earlier presented with epigastric pain and diarrhea of 1 month’s duration. The full blood count showed normal results. Upper GI endoscopy revealed flat elevated lesions in the greater curvature of the gastric body (A, B). Histopathologic study revealed infiltration of the lamina propria with neoplastic lymphoid cells. Immunohistochemical analysis showed expression of CD3, CD79a, and PAX-5; and Ki-67 was 90% of the cells (C, D).


    Date de mise en ligne : Samedi 18 mars 2017
    Saad A. Khan, Jeremy P. Dwyer, Rhys Vaughan
    Peritoneal carcinomatosis from signet-ring cell adenocarcinoma of the appendix
    A 50-year-old man was seen because of 6 weeks of generalized abdominal pain, anorexia, weight loss, and constipation. CT of the abdomen revealed a large amount of intraperitoneal fluid and nodular, striated soft tissue within the fat anterior to the transverse colon (A), consistent with peritoneal carcinomatosis. No primary site of malignancy or evidence of distant metastases was identified. Tumor marker CA19-9 was elevated at 381 kU/L (normal, <37 kU/L), and the carcinoembryonic antigen level was normal.


    Date de mise en ligne : Samedi 18 mars 2017
    Marietta Iacucci, Marco Daperno, Mark Lazarev, Razvan Arsenascu, Gian Eugenio Tontini, Oluseyi Akinola, Xianyong Sean Gui, Vincenzo Villanacci, Martin Goetz, Mark Lowerison, Brendan Cord Lethebe, Maurizio Vecchi, Helmut Neumann, Subrata Ghosh, Raf Bisschops, Ralf Kiesslich
    Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis
    Endoscopic inflammation and healing are important therapeutic endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual chromoendoscopy (EVC) score that could reflect the full spectrum of mucosal and vascular changes including mucosal healing in UC.


    Date de mise en ligne : Samedi 18 mars 2017
    Anne-Fré Swager, Fons van der Sommen, Sander R. Klomp, Sveta Zinger, Sybren L. Meijer, Erik J. Schoon, Jacques J.G.H.M. Bergman, Peter H. de With, Wouter L. Curvers
    Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy
    Volumetric laser endomicroscopy (VLE) is an advanced imaging system that provides a near-microscopic resolution scan of the esophageal wall layers up to 3-mm deep. VLE has the potential to improve detection of early neoplasia in Barrett’s esophagus (BE). However, interpretation of VLE images is complex because of the large amount of data that need to be interpreted in real time. The aim of this study was to investigate the feasibility of a computer algorithm to identify early BE neoplasia on ex vivo VLE images.


    Date de mise en ligne : Lundi 13 mars 2017
    Andrea Oliver Tal, Fabian Finkelmeier, Natalie Filmann, Leena KylĂ€npÀÀ, Marianne Udd, Ilaria Parzanese, Paolo CantĂč, Alexander DechĂȘne, Volker Penndorf, Andreas Schnitzbauer, Mireen Friedrich-Rust, Stefan Zeuzem, Jörg G. Albert
    Multiple plastic stents versus covered metal stent for treatment of anastomotic biliary strictures after liver transplantation: a prospective, randomized, multicenter trial
    Treatment of anastomotic biliary strictures (ABSs) after orthotopic liver transplantation by endoscopic insertion of multiple plastic stents (MPSs) is well established. The use of covered self-expandable metal stents (cSEMSs) for this indication is less investigated.


    Date de mise en ligne : Vendredi 10 mars 2017
    Douglas G. Adler, Ali A. Siddiqui
    Endoscopic management of esophageal strictures
    Esophageal strictures remain a commonly encountered clinical entity. These strictures arise because of a wide variety of benign and malignant conditions. Dysphagia, the most common symptom, occurs when a stricture causes greater than 50% of the esophageal lumen to be obstructed as a result of benign or malignant disease. From a treatment point of view, some esophageal strictures are readily treated via minimally invasive and low-risk means, whereas others can be refractory and recalcitrant to the most aggressive endoscopic therapies.


    Date de mise en ligne : Vendredi 10 mars 2017
    Hae Won Kim, Jie-Hyun Kim, Jun Chul Park, Mi Young Jeon, Yong Chan Lee, Sang Kil Lee, Sung Kwan Shin, Hyun Soo Chung, Sung Hoon Noh, Jong Won Kim, Seung Ho Choi, Jae Jun Park, Young Hoon Youn, Hyojin Park
    Additive endoscopic resection may be sufficient for patients with a positive lateral margin after endoscopic resection of early gastric cancer
    No well-established treatment strategies exist for lateral margin positivity (LM+) alone after endoscopic resection (ER) of early gastric cancer (EGC). Thus, we aimed to clarify a treatment strategy for non-curative resection (non-CR) with LM+ alone after ER in EGC.


    Date de mise en ligne : Vendredi 10 mars 2017
    Wenjie Liu, Min Wang, Lili Zhao, Min Wang, Xiang Wang, Zhining Fan, Li Liu
    Thermo-sensitive isopentane aerification for mucosal lift during endoscopic resection in animal models (with video)
    Mucosal lift is critical for successful endoscopic treatment. Normal saline (NS) solution is widely used as the submucosal filler, but its short persistency restricts clinical endoscopic submucosal dissection (ESD). In this study, thermo-sensitive isopentane was introduced for submucosal injection. With a boiling point at 27.8°C, liquid isopentane can be easily applied, and gasification inflation can provide great support for submucosal lifting at body temperature. The feasibility and efficiency of isopentane were evaluated in this study.


    Date de mise en ligne : Jeudi 09 mars 2017
    Min Min, Pei Deng, Wenhua Zhang, Xiaomin Sun, Yan Liu, Bing Nong
    Comparison of linked color imaging and white-light colonoscopy for detection of colorectal polyps: a multicenter, randomized, crossover trial
    Linked color imaging (LCI), a recently developed technology, uses a laser endoscopic system to enhance the color separation of red color to depict red and white colors more vividly. The benefits of LCI in the detection of colorectal polyps remain unknown. The aim of this study was to assess the ability of LCI to improve the detection of colorectal polyps compared with white-light (WL) endoscopy.


    Date de mise en ligne : Jeudi 09 mars 2017
    Somashekar G. Krishna, William R. Brugge, John M. Dewitt, Pradermchai Kongkam, Bertrand Napoleon, Carlos Robles-Medranda, Damien Tan, Samer El-Dika, Sean McCarthy, Jon Walker, Mary E. Dillhoff, Andrei Manilchuk, Carl Schmidt, Benjamin Swanson, Zarine K. Shah, Phil A. Hart, Darwin L. Conwell
    Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos)
    EUS-guided needle-based confocal laser endomicroscopy (nCLE) characteristics of common types of pancreatic cystic lesions (PCLs) have been identified; however, surgical histopathology was available in a minority of cases. We sought to assess the performance characteristics of EUS nCLE for differentiating mucinous from non-mucinous PCLs in a larger series of patients with a definitive diagnosis.


    Date de mise en ligne : Jeudi 09 mars 2017
    Rui Huang, Hongwei Cai, Xin Zhao, Xiaoqiang Lu, Min Liu, Wenhao Lv, Zhiguo Liu, Kaichun Wu, Ying Han
    Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma: a propensity score matching analysis
    Esophageal endoscopic submucosal dissection (ESD) is technically challenging because of the thinner wall and narrow lumen. The tunnel technique was proposed previously. This current retrospective study aimed to evaluate the efficacy of the tunnel technique in ESD of superficial esophageal squamous cell carcinoma (ESCC).


    Date de mise en ligne : Mercredi 08 mars 2017
    Orly Sneh Arbib, Valentina Zemser, Yaara Leibovici Weissman, Rachel Gingold-Belfer, Alex Vilkin, Sapir Eizenstein, Arnon Cohen, Doron Comaneshter, Shochat Tzipora, Yaron Niv, Yeuda Ringel, David Lieberman, Zohar Levi
    Risk of advanced lesions at the first follow-up colonoscopy after polypectomy of diminutive versus small adenomatous polyps of low-grade dysplasia
    The current guidelines for surveillance after polypectomy do not distinguish between diminutive (1-5 mm) and small (6-9 mm) polyps with low-grade dysplasia (LGD). We aimed to evaluate the risk for advanced neoplasia on follow-up colonoscopy.


    Date de mise en ligne : Mercredi 08 mars 2017
    Mi Gang Kim, Se Woo Park, Jae Hyun Kim, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi
    Etomidate versus propofol sedation for complex upper endoscopic procedures: a prospective double-blinded randomized controlled trial
    Although a growing body of evidence demonstrates that propofol-induced deep sedation can be effective and performed safely, cardiopulmonary adverse events have been observed frequently. Etomidate is a new emerging drug that provides hemodynamic and respiratory stability, even in high-risk patient groups. The objective of this study was to compare safety and efficacy profiles of etomidate and propofol for endoscopic sedation.


    Date de mise en ligne : Mardi 07 mars 2017
    Bing Hu, Bo Sun, Qiang Cai, James Yun Wong Lau, Shuren Ma, Takao Itoi, Jong Ho Moon, Ichiro Yasuda, Xiaofeng Zhang, Hsiu-Po Wang, Shomei Ryozawa, Rungsun Rerknimitr, Wen Li, Hiromu Kutsumi, Sundeep Lakhtakia, Hideyuki Shiomi, Ming Ji, Xun Li, Dongmei Qian, Zhuo Yang, Xiao Zheng
    Asia-Pacific consensus guidelines for endoscopic management of benign biliary strictures
    The primary goal of treatment for benign biliary strictures (BBSs) is to resolve bile duct obstruction, to achieve long-term ductal patency, and to maintain liver function. The endoscopic approach has become the first-line option for most cases of BBS. Biliary drainage can be maintained through a combination of endoscopic stricture dilation and biliary stenting. The effectiveness, clinical success, and outcomes of endoscopic intervention for BBSs largely depend on specific etiologies, endoscopic techniques used, and the selection of appropriate accessories and stents, which varies in the literature.


    Date de mise en ligne : Mardi 07 mars 2017
    Dina S. Ahmad, Khalid Sahak, Audrey J. Lazenby, Ishfaq Bhat
    Chronic mesenteric ischemia and gastric ischemia: a bad combination
    An 83-year-old woman with a medical history significant for atrial fibrillation, type 2 diabetes, and chronic obstructive pulmonary disease (COPD) presented with diffuse postprandial abdominal pain, nausea, and vomiting. The results of her examination were significant for moderate epigastric abdominal tenderness. CT of the abdomen without contrast medium revealed extensive calcific atherosclerotic disease of the abdominal aorta. Magnetic resonance angiography showed advanced atherosclerotic vascular disease with high-grade stenosis at the origin of the celiac artery and high-grade narrowing at the origin of the superior mesenteric artery (SMA) (A).


    Date de mise en ligne : Dimanche 05 mars 2017
    Nicolas Musquer, Merzouka Zidane-Marinnes, Mamoun Dib
    Primary mucosa-associated lymphoid tissue lymphoma of the entire esophagus
    An 85-year-old man with no medical history of digestive disease was admitted for dysphagia. A gastroscopy revealed, despite sufficient insufflation, a narrowing of the entire esophagus lumen with normal mucosa (A). Deep biopsies (bite-on-bite biopsies) were performed with conventional-sized biopsy forceps. Chest CT showed an important thickening of the entire esophageal wall (B). EUS confirmed this regular thickening without lymph node metastasis. Histopathologic examination showed an important submucosal infiltration of lymphocytes with B cell markers (CD20+/CD10−) (C) corresponding to a mucosa-associated lymphoid tissue lymphoma (MALT) of the esophagus.


    Date de mise en ligne : Mercredi 01 mars 2017
    Markus Dollhopf, Alberto Larghi, Uwe Will, Mihai RimbaƟ, Andrea Anderloni, Andres Sanchez-Yague, Anthony Yuen Bun Teoh, Rastislav Kunda
    EUS-guided gallbladder drainage in patients with acute cholecystitis and high surgical risk using an electrocautery-enhanced lumen-apposing metal stent device
    In high-risk surgical patients, the treatment of choice of acute cholecystitis is percutaneous transhepatic gallbladder drainage (PTGBD). Recently, a novel endoscopic device containing a lumen-apposing metal stent with an electrocautery (ECE-LAMS) on the tip has been developed.


    Date de mise en ligne : Mercredi 01 mars 2017
    Masaya Suenaga, Yoshihiko Sadakari, Jose Alejandro Almario, Michael Borges, Anne-Marie Lennon, Eun-Ji Shin, Marcia Irene Canto, Michael Goggins
    Using an endoscopic distal cap to collect pancreatic fluid from the ampulla (with video)
    Duodenal collections of pancreatic fluid can be used as a source of mutations and other markers of pancreatic ductal neoplasia, but admixing pancreatic juice with duodenal contents lowers the concentrations of mutations. Collecting pancreatic fluid directly from the ampulla could yield a purer sample of pancreatic fluid.


    Date de mise en ligne : Mardi 28 février 2017
    Lorenzo Fuccio, Cesare Hassan, Thierry Ponchon, Daniele Mandolesi, Andrea Farioli, Alessandro Cucchetti, Leonardo Frazzoni, Pradeep Bhandari, Cristina Bellisario, Franco Bazzoli, Alessandro Repici
    Clinical outcomes after endoscopic submucosal dissection for colorectal neoplasia: a systematic review and meta-analysis
    Endoscopic submucosal dissection (ESD) is an endoscopic resection technique for lesions suspicious of superficial malignancy. It is performed using an ESD knife on its own (standard technique) or by the sequential use of a knife and a snare (hybrid technique). The experience with these techniques is different in Asian and non-Asian countries. We performed a systematic review and meta-analysis of available evidence on colorectal ESD.


    Date de mise en ligne : Mardi 28 février 2017
    Laith H. Jamil, Amir Kashani, Neiveen Peter, Simon K. Lo
    Safety and efficacy of cap-assisted EMR for sporadic nonampullary duodenal adenomas
    Eradication of sporadic nonampullary duodenal adenomas (SNADAs) is essential because of their high rate of malignant transformation. EMR techniques are the alternative to the traditional surgical treatments of SNADAs. There are very limited data on the safety and efficacy of cap-assisted EMR (C-EMR) in the treatment of SNADA.


    Date de mise en ligne : Mardi 28 février 2017
    Kyoku Sumimoto, Shinji Tanaka, Kenjiro Shigita, Nana Hayashi, Daiki Hirano, Yuzuru Tamaru, Yuki Ninomiya, Shiro Oka, Koji Arihiro, Fumio Shimamoto, Masaharu Yoshihara, Kazuaki Chayama
    Diagnostic performance of Japan NBI Expert Team classification for differentiation among noninvasive, superficially invasive, and deeply invasive colorectal neoplasia
    The Japan NBI Expert Team (JNET) classification is the first universal narrow-band imaging magnifying endoscopic classification of colorectal tumors. Considering each type in this classification, the diagnostic ability of Type 2B is the weakest. Generally, clinical behavior is believed to be different in each gross type of colorectal tumor. We evaluated the differences in the diagnostic performance of JNET classification for each gross type (polypoid and superficial) and examined whether the diagnostic performance of Type 2B could be improved by subtyping.


    Date de mise en ligne : Jeudi 23 février 2017
    Riccardo Solimando, Alessandro Pezzoli, Viviana CifalĂ , Lucio Trevisani, Paolo Pazzi
    Unexpected finding after gastroduodenal artery embolization
    An 87-year-old woman with melena and anemia was admitted to the hospital and underwent urgent GI endoscopy. During the procedure, a large clot adhering to the posterior wall of the duodenal bulb was identified. Its removal with a retrieval net revealed an underlying visible vessel with active oozing (A). After an ineffective attempt to obtain endoscopic hemostasis with epinephrine injection, argon plasma coagulation, and clips, interventional radiology was performed. Selective arteriography of the celiac trunk revealed no extravasation, so blind embolization of the gastroduodenal artery with 3 platinum coils (SPIRALES.018″, coil ∅ 3 mm, coil length 5 cm; Balt Extrusion, Montmorency, France) was carried out (B, continous arrow: coil; dashed arrow: clip).


    Date de mise en ligne : Jeudi 23 février 2017
    Silvia Carrara, Milena Di Leo, Alessandro Repici
    Not only biliary, but also ureteral stones can be detected by EUS


    Date de mise en ligne : Jeudi 23 février 2017
    Rui Gaspar, Pedro Moutinho-Ribeiro, Guilherme Macedo
    Bullous pemphigoid: extensive esophageal involvement
    A 73-year-old woman with a medical history of bullous pemphigoid diagnosed in 2013, who was being treated with prednisolone 20 mg daily, was admitted to our internal medicine department with Escherichia coli urosepsis. She began treatment with ceftriaxone 2 g/day, and the dose of oral prednisolone was lowered to 10 mg/day.


    Date de mise en ligne : Jeudi 23 février 2017
    Ervin Alibegovic, Admir Kurtcehajic, Ahmed Hujdurovic, Adnan Zeco, Dzenita Kurtcehajic
    Acute submucosal hematoma: an adverse event of routine colonoscopy
    A 20-year-old woman underwent diagnostic colonoscopy because of nonspecific lower abdominal pain and problems with elimination (diarrhea and constipation). She had no history of any serious disease or surgery. Her body mass index was 20.2, and the results of physical examination were unremarkable. Her complete blood count was within normal limits, as were nonspecific inflammatory parameters (erythrocyte sedimentation rate, C-reactive protein). The values for biochemical tests including coagulation were within normal ranges.


    Date de mise en ligne : Jeudi 23 février 2017
    Xiaoyu Tang, Yuyong Tan, Deliang Liu
    Angiolipoma: a rare esophageal submucosal tumor
    A 50-year-old man came to our hospital with a 1-month history of chest discomfort. The discomfort increased while he was eating solid food, and he did not describe any retrosternal pain or acid regurgitation. There was no family history of GI cancer. The results of physical examination and laboratory tests were unremarkable. EGD revealed a soft columnar polypoid mass measuring 1.5 × 1.8 cm about 20 cm from the incisors (A), with normal overlying mucosa. EUS showed a homogeneous hyperechoic mass localized in the submucosal layer, without malignant features (B).


    Date de mise en ligne : Mardi 21 février 2017
    Yen-I Chen, Haruhiro Inoue, Michael Ujiki, Peter V. Draganov, Paul Colavita, Francois Mion, John Romanelli, Philip Chiu, Valerio Balassone, Lava Patel, Ali Abbas, Dennis Yang, Christy Dunst, Mathieu Pioche, Sabine Roman, JĂ©rĂŽme Rivory, Thierry Ponchon, David Desilets, Roberta Maselli, Manabu Onimaru, Jun Nakamura, Yoshitaka Hata, Gulara Hajiyeva, Amr Ismail, Saowanee Ngamruengphong, Majidah Bukhari, Yamile Haito Chavez, Vivek Kumbhari, Alessandro Repici, Mouen A. Khashab
    An international multicenter study evaluating the clinical efficacy and safety of per-oral endoscopic myotomy in octogenarians
    Per-oral endoscopic myotomy (POEM) for achalasia is particularly appealing in the elderly because it is minimally invasive. However, data in patients aged ≄80 years are scarce. The aim of this study was to assess the clinical outcome of POEM in octogenarians.


    Date de mise en ligne : Mardi 21 février 2017
    Fariha H. Ramay, Qingping Cui, Bruce D. Greenwald
    Outcomes after liquid nitrogen spray cryotherapy in Barrett's esophagus–associated high-grade dysplasia and intramucosal adenocarcinoma: 5-year follow-up
    Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett’s esophagus (BE)–associated high-grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking.


    Date de mise en ligne : Lundi 20 février 2017
    Tejas Kirtane, Bharat Bhandari, Larry D. Scott, Shashideep Singhal
    Overtube-assisted pneumatic dilation for achalasia in megaesophagus
    We present an overtube-assisted technique for pneumatic dilation for achalasia in challenging cases in patients who have developed megaesophagus. A 63-year-old man with a long-standing history of achalasia presented for evaluation of dysphagia and regurgitation of food. Achalasia was initially diagnosed with an upper GI series more than 20 years previously and was subsequently confirmed by esophageal manometry 8 years before presentation. The patient had undergone at least 4 pneumatic dilations with good response over 2 decades, had been relatively asymptomatic between dilations, and had refused surgical intervention in the past.


    Date de mise en ligne : Vendredi 10 février 2017
    Takuto Suzuki, Taro Hara, Yoshiyasu Kitagawa, Hideyuki Takashiro, Rino Nankinzan, Osamu Sugita, Taketo Yamaguchi
    Linked-color imaging improves endoscopic visibility of colorectal nongranular flat lesions
    As a newly developed image-enhanced endoscopy (IEE) technique, linked-color imaging (LCI) provides very bright images with enhanced color tones. With the objective of improving the detection rate of colorectal flat tumor lesions, which are difficult to detect, we examined the usefulness of LCI from the viewpoint of visibility.


    Date de mise en ligne : Mercredi 08 février 2017
    Shishira Bharadwaj, Bo Shen
    Medical, endoscopic, and surgical management of ileal pouch strictures (with video)
    The construction of ileal pouch–anal anastomosis (IPAA) is the procedure of choice for patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Furthermore, IPAA has the advantage of preserving the natural route of defecation, unlike the Brooke’s ileostomy or continent ileostomies. On the other hand, the natural history of patients with the ileal pouch can be complicated by various surgical procedure–associated mechanical adverse events as well as inflammatory and functional disorders.


    Date de mise en ligne : Mardi 07 février 2017
    Wouter F.W. Kappelle, Ronald L.A.W. Bleys, Albert J.M. van Wijck, Peter D. Siersema, Frank P. Vleggaar
    EUS-guided celiac ganglia neurolysis: a clinical and human cadaver study (with video)
    There is little evidence that structures targeted during EUS-guided celiac ganglia neurolysis (EUS-CGN) are celiac ganglia and that selective ethanol injection into ganglia is feasible. We aimed to visualize celiac ganglia, confirm that these structures are ganglia, and visualize ethanol spread after EUS-CGN and EUS-guided celiac plexus neurolysis (EUS-CPN).


    Date de mise en ligne : Mardi 07 février 2017
    Ankie Reumkens, Ad A. Masclee, Bjorn Winkens, Cees T. van Deursen, Silvia Sanduleanu, Christine M. Bakker
    Prevalence of hypokalemia before and after bowel preparation for colonoscopy in high-risk patients
    Bowel preparation for colonoscopy should not cause significant shifts in systemic electrolyte concentrations. We recently encountered 2 cases of severe postcolonoscopy hypokalemia with fatal consequences, prompting us to conduct a study to explore the magnitude of and risk factors for hypokalemia associated with bowel preparation. We paid specific attention to higher-risk subgroups, in particular, diuretic users, hospitalized patients, and patients estimated at to be high risk by the gastroenterologist.


    Date de mise en ligne : Mardi 07 février 2017
    Ningli Chai, Jia Feng, Yuhang Guo, Huikai Li, Bo Ning, Xiangdong Wang, Ying Wang, Yonghua Wang, Yaqi Zhai, Enqiang Linghu
    Preliminary study of single-operator cholangioscopy for diagnosing pancreatic cystic lesions
    Advances in imaging technology have improved the annual detection rate of pancreatic cystic lesions (PCLs), but the preoperative diagnosis of PCLs remains unclear. Thus, the usefulness of single-operator cholangioscopy (SOC) as a diagnostic imaging tool for PCLs is worth investigating. We performed an intracystic visual examination of PCLs using SOC to determine the diagnostic value of SOC for PCLs.


    Date de mise en ligne : Samedi 04 février 2017
    Huiqin He, Chenfei Tan, Jiaguo Wu, Ning Dai, Weiling Hu, Yawen Zhang, Loren Laine, James Scheiman, John J. Kim
    Accuracy of ASGE high-risk criteria in evaluation of patients with suspected common bile duct stones
    ERCP is recommended for patients considered high risk for choledocholithiasis after biochemical testing and abdominal US. Our aim was to determine whether the American Society for Gastrointestinal Endoscopy (ASGE) guidelines accurately select patients for whom the risk of ERCP is justified.


    Date de mise en ligne : Samedi 04 février 2017
    Shozo Osera, Hiroaki Ikematsu, Satoshi Fujii, Keisuke Hori, Yasuhiro Oono, Tomonori Yano, Kazuhiro Kaneko
    Endoscopic treatment outcomes of laterally spreading tumors with a skirt (with video)
    A “skirt” is a slightly elevated flat lesion with wide pits occasionally observed at the margin of laterally spreading tumors (LSTs). However, the endoscopic treatment outcomes of LSTs with skirts have not been clarified. The aim of this study was to evaluate the endoscopic treatment outcomes of LSTs with skirts.


    Date de mise en ligne : Samedi 04 février 2017
    Tannaz Guivatchian, Erika S. Koeppe, Jason R. Baker, Cristina Moisa, Matthew Demerath, Caitlin Foor-Pessin, William D. Chey, Shanti L. Eswaran, Joseph C. Kolars, Stacy B. Menees, Michael Rajala, Michael D. Rice, Rafat Rizk, Joel H. Rubenstein, Pratima Sharma, Andrea Todisco, Elena M. Stoffel
    Family history in colonoscopy patients: feasibility and performance of electronic and paper-based surveys for colorectal cancer risk assessment in the outpatient setting
    Family history is crucial in stratifying patients’ risk for colorectal cancer (CRC). Previous risk assessment tools developed for use in clinic or endoscopy settings have demonstrated suboptimal specificity for identifying patients with hereditary cancer syndromes. Our aim was to test the feasibility and performance of 2 family history surveys (paper and electronic) in individuals presenting for outpatient colonoscopy.


    Date de mise en ligne : Samedi 04 février 2017
    Abdul M. Kouanda, Ma Somsouk, Justin L. Sewell, Lukejohn W. Day
    Urgent colonoscopy in patients with lower GI bleeding: a systematic review and meta-analysis
    Lower GI bleeding (LGIB) is a common cause of morbidity and mortality. Colonoscopy is indicated in all hospitalized patients with LGIB, yet the time frame for performing colonoscopy remains unclear. Prior studies of outcomes in urgent versus elective colonoscopy have yielded conflicting results and were often underpowered. Our study objective was to compare several outcomes between urgent and elective colonoscopy in patients hospitalized for LGIB.


    Date de mise en ligne : Vendredi 03 février 2017
    Hsiang-Chieh Lee, Osman O. Ahsen, Kaicheng Liang, Zhao Wang, Marisa Figueiredo, Michael G. Giacomelli, Benjamin Potsaid, Qin Huang, Hiroshi Mashimo, James G. Fujimoto
    Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus (with video)
    Angiogenesis is associated with neoplastic progression of Barrett’s esophagus (BE). Volumetric optical coherence tomography angiography (OCTA) visualizes subsurface microvasculature without exogenous contrast agents. We investigated the association of OCTA microvascular features with low-grade dysplasia (LGD) and high-grade dysplasia (HGD).


    Date de mise en ligne : Vendredi 03 février 2017
    Árpåd Patai, Norbert Solymosi, Låszló Mohåcsi, Árpåd V. Patai
    Indomethacin and diclofenac in the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis of prospective controlled trials
    Diclofenac and indomethacin are the most studied drugs for preventing post-ERCP pancreatitis (PEP). However, there are no prospective, randomized multicenter trials with a sufficient number of patients for correct evaluation of their efficacy. Our aim was to evaluate all prospective trials published in full text that studied the efficacy of diclofenac or indomethacin and were controlled with placebo or non-treatment for the prevention of PEP in adult patients undergoing ERCP.


    Date de mise en ligne : Mercredi 01 février 2017
    Sunil Dacha, Parit Mekaroonkamol, Lianyong Li, Nikrad Shahnavaz, Sonali Sakaria, Steven Keilin, Field Willingham, Jennifer Christie, Qiang Cai
    Outcomes and quality-of-life assessment after gastric per-oral endoscopic pyloromyotomy (with video)
    Gastric per-oral endoscopic pyloromyotomy (GPOEM) is emerging as a promising option for the treatment of gastroparesis. This study assessed outcomes and quality of life after GPOEM for gastroparesis, performed in an endoscopy unit at a major tertiary referral center.


    Date de mise en ligne : Mercredi 01 février 2017
    A. Swager, A.J. de Groof, S.L. Meijer, B.L. Weusten, W.L. Curvers, Jacques J. Bergman
    Feasibility of laser marking in Barrett’s esophagus with volumetric laser endomicroscopy: first-in-man pilot study
    Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers and has potential to improve detection of neoplasia in Barrett’s esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks (LMs) in different esophageal tissue types on white light endoscopy (WLE) and VLE.


    Date de mise en ligne : Mercredi 01 février 2017
    Alessandro Repici, Roberta Maselli, Silvia Carrara, Andrea Anderloni, Markus Enderle, Cesare Hassan
    Standard needle versus needleless injection modality: animal study on different fluids for submucosal elevation
    Submucosal injection is currently used in GI endoscopy to reduce resection risks and to perform submucosal dissection; it is usually performed via an injection needle or a needleless device. The aim of the study was to compare 2 submucosal injection modalities (needle-assisted vs needleless) by using substances with different viscosities


    Date de mise en ligne : Mardi 31 janvier 2017
    Hamita Sachar, Nipaporn Pichetshote, Kavitha Nandigam, Keta Vaidya, Loren Laine
    Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial
    Current guidelines recommend diphenhydramine in patients undergoing endoscopy who are not adequately sedated with a benzodiazepine and opioid combination. Because this practice has not been adequately assessed, we performed a randomized, double-blind trial comparing diphenhydramine with continued midazolam in such patients.


    Date de mise en ligne : Mardi 31 janvier 2017
    Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
    Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST)
    Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett’s neoplasia and has advantages over conventional EMR in that it enables en-bloc resection and accurate histopathologic analysis of cancer resection margins. However, its long learning curve and higher adverse event rate have tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett’s neoplasia. The primary endpoint was the en-bloc and R0 resection rate.


    Date de mise en ligne : Mardi 31 janvier 2017
    Bo Shen
    Exploring endoscopic therapy for the treatment of Crohn’s disease–related fistula and abscess
    Fistula and abscess represent penetrating disease phenotypes of Crohn’s disease (CD) and can develop in patients with or without prior history of CD-related surgery. While CD fistula and abscess have been traditionally treated with medical and surgical therapy, the role of endoscopic therapy in this particular phenotype of CD is expanding recently, thanks to advanced endoscopic techniques and a better understanding of pathogenesis and natural history of the disease and principle of treatment. The success of endoscopic treatment for inflammatory bowel disease depends on comprehension and appreciation of principles, then techniques, followed by instrument and device.


    Date de mise en ligne : Mardi 31 janvier 2017
    Takeshi Mizushima, Shunsuke Ohnishi, Hidetaka Hosono, Kenichi Yamahara, Momoko Tsuda, Yuichi Shimizu, Mototsugu Kato, Masahiro Asaka, Naoya Sakamoto
    Oral administration of conditioned medium obtained from mesenchymal stem cell culture prevents subsequent stricture formation after esophageal submucosal dissection in pigs
    Endoscopic submucosal dissection (ESD) for esophageal cancer often causes postoperative stricture when more than three fourths of the circumference of the esophagus is dissected. Mesenchymal stem cells are a valuable cell source in regenerative medicine, and conditioned medium (CM) obtained from mesenchymal stem cells reportedly inhibits inflammation. In this study we evaluated whether CM could prevent esophageal stricture after ESD.


    Date de mise en ligne : Lundi 30 janvier 2017
    Joseph C. Anderson, Lynn F. Butterly, Julia E. Weiss, Christina M. Robinson
    Providing data for serrated polyp detection rate benchmarks: an analysis of the New Hampshire Colonoscopy Registry
    Similar to achieving adenoma detection rate (ADR) benchmarks to prevent colorectal cancer (CRC), achieving adequate serrated polyp detection rates (SDRs) may be essential to the prevention of CRC associated with the serrated pathway. Previous studies have been based on data from high-volume endoscopists at single academic centers. Based on a hypothesis that ADR is correlated with SDR, we stratified a large, diverse group of endoscopists (n = 77 practicing at 28 centers) into high performers and low performers, based on ADR, to provide data for corresponding target SDR benchmarks.


    Date de mise en ligne : Lundi 30 janvier 2017
    Zibing Woodward, Zaida Rodriguez, Janice H. Jou, Kian Keyashian, Yiyi Chen, Charles R. Thomas, Grace H. Elta, Sharlene L. D’Souza
    Gender disparities in gastroenterology fellowship director positions in the United States
    Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims to determine whether this trend exists in 3-year gastroenterology fellowships in the United States and to evaluate for any factors that may affect these differences.


    Date de mise en ligne : Dimanche 29 janvier 2017
    Hiroaki Ikematsu, Taku Sakamoto, Kazutomo Togashi, Naohisa Yoshida, Takashi Hisabe, Shinsuke Kiriyama, Koji Matsuda, Yoshikazu Hayashi, Takahisa Matsuda, Shozo Osera, Kazuhiro Kaneko, Kenichi Utano, Yuji Naito, Hiroshi Ishihara, Masayuki Kato, Kenichi Yoshimura, Hideki Ishikawa, Hironori Yamamoto, Yutaka Saito
    Detectability of colorectal neoplastic lesions using a novel endoscopic system with blue laser imaging: a multicenter randomized controlled trial
    Most studies have not reported an improvement in the detection of adenomas with the use of image-enhanced colonoscopy methods, possibly because of the darkness of the images. To overcome this limitation, a new-generation endoscopic system has been developed. This system has 2 blue-laser imaging (BLI) observation modes. The BLI observation was set to BLI-bright mode to detect lesions. We aimed to evaluate the efficacy of BLI in detecting lesions.


    Date de mise en ligne : Dimanche 29 janvier 2017
    Fabio S. Kawaguti, Adriana R. de Andrade, Stephanie Wodak, Bruno Costa Martins, Fauze Maluf-Filho
    Complete therapeutic response of a large tubulovillous adenoma after chemotherapy
    We describe the case of a woman who underwent urgent right hemicolectomy for obstructive advanced neoplasia. Histopathologic examination revealed poorly differentiated mucinous adenocarcinoma with invasion to the subserosa without vascular or perineural invasion. Seven of 28 resected regional lymph nodes were metastatic (pT3pN2M0). Immunohistochemical study showed microsatellite instability. Adjuvant chemotherapy with oxaliplatin, 5-fluorouracil, leucovorin, and folinic acid was initiated. Colonoscopy revealed a 40-mm sessile polyp in the sigmoid colon with a noninvasive aspect at magnification.


    Date de mise en ligne : Samedi 28 janvier 2017
    Iyad Khamaysi, Yoram Kluger
    The water-lily sign
    A 23-year-old healthy woman presented with epigastric pain. The result of gastroscopy was normal. CT showed 2 adjacent cysts in the lesser sac: a unilocular cyst (A, black arrow) and a septated cyst (A, white arrow). EUS demonstrated 2 cystic lesions: the first cyst was anechoic unilocular, with a thick calcified wall, and the second lesion contained floating laminated membranes within a dense fibrous cystic wall—a finding termed the water-lily sign (B). A hydatid cyst was suspected. Puncture was not performed.


    Date de mise en ligne : Vendredi 27 janvier 2017
    Eun Jung Jun, Jung-Hoon Park, Jiaywei Tsauo, Su-Geun Yang, Dae-Kee Kim, Kun Yung Kim, Min Tae Kim, Sung-Hwan Yoon, Young Je Lim, Ho-Young Song
    EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus
    Self-expanding metallic stent (SEMS) placement is a well-established method for treating malignant esophageal strictures; however, this procedure has not gained widespread acceptance for treating benign esophageal strictures because of granulation tissue formation. The aim of the present study was to investigate whether EW-7197, a novel per-oral transforming growth factor-ÎČ type I receptor kinase inhibitor, suppressed granulation tissue formation after SEMS placement in the rat esophagus.


    Date de mise en ligne : Vendredi 27 janvier 2017
    Timo Rath, Christian Bojarski, Markus F. Neurath, Raja Atreya
    Molecular imaging of mucosal α4ÎČ7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn’s disease
    Molecular imaging is based on the use of fluorescent probes with specificity toward defined molecular targets and their visualization by endoscopic devices such as confocal laser endomicroscopy (CLE). Herein, we describe successful molecular imaging of the α4ÎČ7 integrin through CLE in Crohn’s disease (CD). Five patients with CD refractory to anti-tumor necrosis factor (TNF) therapy and with active mucosal inflammation, as shown by high-definition endoscopy, were studied (A). Before induction therapy with the anti-α4ÎČ7 antibody vedolizumab (VDZ), molecular imaging of α4ÎČ7 with fluorescein isothiocyanate (FITC)–labeled VDZ allowed specific identification of α4ÎČ7 expressing mucosal cells with clear discrimination against FITC-IgG1 isotype control in 2 patients with CD responding to subsequent VDZ therapy (B).


    Date de mise en ligne : Vendredi 27 janvier 2017
    Tomonori Yano, Yusuke Yoda, Shogo Nomura, Kayo Toyosaki, Hiromi Hasegawa, Hiroyuki Ono, Masaki Tanaka, Hiroyuki Morimoto, Takahiro Horimatsu, Satoru Nonaka, Kazuhiro Kaneko, Akihiro Sato
    Prospective trial of biodegradable stents for refractory benign esophageal strictures after curative treatment of esophageal cancer
    Biodegradable stents are reportedly effective for refractory benign esophageal strictures; however, little is known about their use in patients with refractory stricture after endoscopic submucosal dissection (ESD) or chemoradiotherapy (CRT) for esophageal cancer. This study aimed to evaluate the effectiveness of biodegradable stents for these patients.


    Date de mise en ligne : Mercredi 25 janvier 2017
    Abdul Hamid El Chafic, David Loren, Ali Siddiqui, Rawad Mounzer, Natalie Cosgrove, Thomas Kowalski
    Comparison of FNA and fine-needle biopsy for EUS-guided sampling of suspected GI stromal tumors
    Subepithelial lesions are found in about 1% of all EGD procedures, and GI stromal tumors are a type of subepithelial lesion commonly encountered. Although the majority of subepithelial lesions are benign, GI stromal tumors have malignant potential, making a definitive diagnosis important. Currently, the criterion standard for the diagnosis of GI stromal tumors is EUS-directed FNA (EUS-FNA). The definitive diagnosis of GI stromal tumors relies on immunohistochemical staining, which depends on enough tissue being submitted to the pathologist.


    Date de mise en ligne : Mercredi 25 janvier 2017
    Guilherme Piovezani Ramos, Korosh Sharain, Karthik Ravi
    Juvenile polyposis and hereditary hemorrhagic telangiectasia overlap syndrome
    A 67-year-old woman with a history of ulcerative colitis, status postproctocolectomy with end ileostomy, presented with persistent iron-deficiency anemia. Her family history was significant for a daughter with gastric cancer and intracranial aneurysms. Physical examination showed multiple cherry angiomas and superficial telangiectasias on her upper back. An extended upper endoscopy revealed several large nonbleeding angioectasias throughout the stomach and the duodenum (A). Additionally, multiple 2-mm to 12-mm pedunculated and sessile polyps with no bleeding were found throughout the duodenum (B).


    Date de mise en ligne : Lundi 09 janvier 2017
    Giovanni D. De Palma, Mariano C. Giglio, Dario Bruzzese, Nicola Gennarelli, Francesco Maione, Saverio Siciliano, Benedetta Manzo, Gianluca Cassese, Gaetano Luglio
    Cap cuff–assisted colonoscopy versus standard colonoscopy for adenoma detection: a randomized back-to-back study
    EndoCuff is a disposable device applied to standard colonoscopes to improve mucosal visualization. Randomized parallel trials have shown that EndoCuff increases the adenoma detection rate (ADR). The primary aim of this study was to compare the ADR between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopies within a randomized back-to-back trial.


    Date de mise en ligne : Lundi 09 janvier 2017
    Loai Mansour, Ferial El-Kalla, Hanan El-Bassat, Sherief Abd-Elsalam, Mohamed El-Bedewy, Abdelrahman Kobtan, Rehab Badawi, Mohamed Elhendawy
    Randomized controlled trial of scleroligation versus band ligation alone for eradication of gastroesophageal varices
    Gastric varices develop in 5% to 33% of patients with portal hypertension. Their most common form is concomitant gastroesophageal varices. Scleroligation (combined sclerotherapy and band ligation) has been used successfully in management of esophageal varices but has not been evaluated previously in the management of gastroesophageal varices. The aim of this work was evaluation of a new scleroligation technique for management of bleeding gastroesophageal varices regarding efficacy, adverse events, variceal recurrence, and survival.


    Date de mise en ligne : Vendredi 06 janvier 2017
    Eelco C. Brand, Vincent K. Dik, Martijn G.H. van Oijen, Peter D. Siersema
    Missed adenomas with behind-folds visualizing colonoscopy technologies compared with standard colonoscopy: a pooled analysis of 3 randomized back-to-back tandem colonoscopy studies
    The Third Eye Retroscope, Full Spectrum Endoscope (FUSE), and EndoRings devices have been shown to reduce overall adenoma miss rates. We evaluated the characteristics of adenomas and patient subgroups for which these behind-folds visualizing technologies mostly reduce adenoma miss rates.


    Date de mise en ligne : Vendredi 06 janvier 2017
    Mona Rezapour, Chidi Amadi, Lauren B. Gerson
    Retention associated with video capsule endoscopy: systematic review and meta-analysis
    Video capsule endoscopy (VCE) has become a major diagnostic tool for small-bowel evaluation. However, retention of the video capsule endoscope remains a major concern.


    Date de mise en ligne : Mardi 03 janvier 2017
    Robert J. Huang, Nirav C. Thosani, Monique T. Barakat, Abhishek Choudhary, Alka Mithal, Gurkirpal Singh, Saurabh Sethi, Subhas Banerjee
    Evolution in the utilization of biliary interventions in the United States: results of a nationwide longitudinal study from 1998 to 2013
    Bile duct surgery (BDS), percutaneous transhepatic cholangiography (PTC), and ERCP are alternative interventions used to treat biliary disease. Our aim was to describe trends in ERCP, BDS, and PTC on a nationwide level in the United States.


    Date de mise en ligne : Mardi 03 janvier 2017
    Zhen-Hua Zhao, Liang-Hao Hu, Hong-Bo Ren, An-Jing Zhao, Yang-Yang Qian, Xiao-Tian Sun, Song Su, Shu-Guang Zhu, Jin Yu, Wen-Bin Zou, Xiao-Rong Guo, Lei Wang, Zhao-Shen Li, Zhuan Liao
    Incidence and risk factors for post-ERCP pancreatitis in chronic pancreatitis
    Almost all studies on post-ERCP pancreatitis (PEP) have mainly involved patients with biliary diseases rather than chronic pancreatitis (CP), and the concept that CP seems to be a protective factor associated with PEP has not been studied in detail. The aim of this study was to determine the incidence of PEP in patients with CP at different clinical stages and to identify the predictive and protective factors of PEP in a large cohort.


    Date de mise en ligne : Vendredi 23 décembre 2016
    Vitor Sousa Medeiros, Bruno Costa Martins, Luciano Lenz, Maria Sylvia Ierardi Ribeiro, Gustavo Andrade de Paulo, Marcelo Simas Lima, Adriana Vaz Safatle-Ribeiro, Fabio Shighuehissa Kawaguti, Caterina Pennacchi, Sebastian N. Geiger, Victor R. Bastos, Ulysses Ribeiro-Junior, Rubens A. Sallum, Fauze Maluf-Filho
    Adverse events of self-expandable esophageal metallic stents in patients with long-term survival from advanced malignant disease
    Self-expandable metallic stents are considered the best palliative treatment of dysphagia for patients with advanced esophageal cancer. Adverse events (AEs) are a major concern, especially in patients with better prognosis and longer survival. The present study aimed to evaluate the AEs of patients who survived longer than 6 months with esophageal stents in place.


    Date de mise en ligne : Vendredi 23 décembre 2016
    Jasper L.A. Vleugels, Yark Hazewinkel, Paul Fockens, Evelien Dekker
    Natural history of diminutive and small colorectal polyps: a systematic literature review
    Diminutive (1-5 mm) and small (6-9 mm) polyps comprise 90% of detected lesions during colonoscopy and rarely contain advanced histology or colorectal cancer (CRC). Routine removal of these lesions results in a significant burden to colonoscopy programs. At the same time, the risk for progression of these polyps to CRC is unclear. We performed a systematic review to explore the natural history of diminutive and small colorectal polyps.


    Date de mise en ligne : Jeudi 22 décembre 2016
    Rintaro Hashimoto, Dai Hirasawa, Akimichi Chonan, Hajime Yamaoka, Masato Nakahori
    “Small white sign” in Barrett’s esophageal cancer under the squamous epithelium
    A 74-year-old man visited our hospital because of epigastric discomfort. EGD revealed a subtle reddish, flat, elevated lesion 40 mm in diameter in the right anterior wall of the esophagogastric junction (A). Examination of a biopsy specimen revealed a well-differentiated adenocarcinoma. Irregular meshlike vessels were observed within the lesion using magnifying narrow-band imaging (NBI) endoscopy (B). Acetic acid spraying revealed multiple small white spots on the neighboring squamous epithelium (C, arrows).


    Date de mise en ligne : Jeudi 22 décembre 2016
    Bryan Rea, Dale Frank
    An uncommon manifestation of acute leukemia
    A 49-year-old man with no significant medical history presented with melena and persistent hematochezia. Colonoscopy revealed a 2.0-cm erythematous polyp in the distal sigmoid colon (A), which was removed by hot snare polypectomy. Hematoxylin and eosin–stained sections showed adenomatous colonic epithelium. The lamina propria was expanded by an infiltrate of large mitotically active cells with irregular nuclei, fine chromatin, and prominent nucleoli (B). Immunohistochemical stains confirmed that they were CD4+ CD15+ CD68+ (C) CD117+ lysozyme+ MPO+ (D) CD34− blasts.


    Date de mise en ligne : Mercredi 21 décembre 2016
    Yuga Komaki, Fukiko Komaki, Dejan Micic, Akio Ido, Atsushi Sakuraba
    Risk of colorectal cancer in chronic liver diseases: a systematic review and meta-analysis
    The risk of colorectal cancer (CRC) in various chronic liver diseases compared with the general population remains unclear. We performed a systematic review and meta-analysis to assess the risk of CRC in patients with chronic liver diseases before and after liver transplantation.


    Date de mise en ligne : Mercredi 21 décembre 2016
    Umar Hayat, Peter J. Lee, Hamid Ullah, Shashank Sarvepalli, Rocio Lopez, John J. Vargo
    Association of prophylactic endotracheal intubation in critically ill patients with upper GI bleeding and cardiopulmonary unplanned events
    Prophylactic endotracheal intubation (PEI) is often advocated to mitigate the risk of cardiopulmonary adverse events in patients presenting with brisk upper GI bleeding (UGIB). However, the benefit of such a measure remains controversial. Our study aimed to compare the incidence of cardiopulmonary unplanned events between critically ill patients with brisk UGIB who underwent endotracheal intubation versus those who did not.


    Date de mise en ligne : Dimanche 18 décembre 2016
    Satoshi Kinoshita, Toshihiro Nishizawa, Yasutoshi Ochiai, Toshio Uraoka, Teppei Akimoto, Ai Fujimoto, Tadateru Maehata, Osamu Goto, Takanori Kanai, Naohisa Yahagi
    Accuracy of biopsy for the preoperative diagnosis of superficial nonampullary duodenal adenocarcinoma
    Endoscopic biopsy sampling for the diagnosis of duodenal adenocarcinoma is not perfect. We investigated the accuracy of biopsy specimen diagnoses of superficial nonampullary duodenal epithelial tumors (NADETs).


    Date de mise en ligne : Jeudi 15 décembre 2016
    David S. Zimmon, Fred B. Smith, Forrest Manheimer, Cathy Fan, Chantel Njiwaji, Sergei Aksenov, Premtesh Chattoo
    Endoscopic multiple biopsy and rapid diagnosis by in situ fixation and histopathologic processing
    Endoscopic forceps biopsy and fixation are laborious and prolong the procedure and anesthesia. Multiple biopsy overcomes these shortcomings with a single endoscope pass that cuts, like a needle biopsy, up to 25 biopsy samples of uniform size and depth during endoscope withdrawal. Biopsy specimens are collected in acquisition order and stored in a perforated plastic storage chamber within the perforated metal tip. The tip is cut off, immersed in fixative, and sent to pathology. A formatted log identifies each biopsy specimen by site and position.


    Date de mise en ligne : Mercredi 14 décembre 2016
    Yu-Hsi Hsieh, Chih-Wei Tseng, Chi-Tan Hu, Malcolm Koo, Felix W. Leung
    Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation
    Adenoma detection rate (ADR), defined as the proportion of patients with at least one adenoma of any size, is a quality indicator. We tested the hypothesis that water exchange (WE) improves ADR but water immersion (WI) has no adverse effect on ADR compared with air insufflation (AI).


    Date de mise en ligne : Vendredi 09 décembre 2016
    K. Nadine Phoa, Wilda D. Rosmolen, Bas L.A.M. Weusten, Raf Bisschops, Erik J. Schoon, Shefali Das, Krish Ragunath, G. Fullarton, Massimiliano DiPietro, Narayanasamy Ravi, Jan G.P. Tijssen, Marcel G.W. Dijkgraaf, Jacques J.G.H.M. Bergman, SURF investigators
    The cost-effectiveness of radiofrequency ablation for Barrett's esophagus with low-grade dysplasia: results from a randomized controlled trial (SURF trial)
    The Surveillance versus Radiofrequency Ablation (SURF) trial randomized 136 patients with Barrett's esophagus (BE) containing low-grade dysplasia (LGD), to receive radiofrequency ablation (ablation, n = 68) or endoscopic surveillance (control, n = 68). Ablation reduced the risk of neoplastic progression to high-grade dysplasia and esophageal adenocarcinoma (EAC) by 25% over 3 years (1.5% for ablation vs 26.5% for control). We performed a cost-effectiveness analysis from a provider perspective alongside this trial.


    Date de mise en ligne : Mardi 06 décembre 2016
    Takemasa Hayashi, Shin-ei Kudo, Hideyuki Miyachi, Tatsuya Sakurai, Tomoyuki Ishigaki, Yusuke Yagawa, Naoya Toyoshima, Yuichi Mori, Masashi Misawa, Toyoki Kudo, Kunihiko Wakamura, Atushi Katagiri, Toshiyuki Baba, Fumio Ishida
    Management and risk factor of stenosis after endoscopic submucosal dissection for colorectal neoplasms
    Although endoscopic submucosal dissection (ESD) enables en bloc removal of large colorectal neoplasms, the incidence of stenosis after ESD and its risk factors have not been well described. This study aimed to determine the risk factors of stenosis and verify the surveillance and treatment of stenosis.


    Date de mise en ligne : Lundi 05 décembre 2016
    Shinichiro Sakata, Antonio H.S. Lee, Ammar O. Kheir, Nicholas J. Tutticci, Sanjeev Naidu, Andrew R.L. Stevenson, David G. Hewett
    Patient acceptance of the optical diagnosis and misdiagnosis of diminutive colorectal polyps
    Optical diagnosis allows for real-time endoscopic assessment of colorectal polyp histology and consists of the resect and discard and diagnose and leave paradigms. This survey assessed patient acceptance of optical diagnosis and their responses to a hypothetical doomsday scenario.


    Date de mise en ligne : Lundi 05 décembre 2016
    Sheila Kumar, Nirav Thosani, Uri Ladabaum, Shai Friedland, Ann M. Chen, Rajan Kochar, Subhas Banerjee
    Adenoma miss rates associated with a 3-minute versus 6-minute colonoscopy withdrawal time: a prospective, randomized trial
    The 6-minute withdrawal time for colonoscopy, widely considered the standard of care, is controversial. The skill and technique of endoscopists may be as important as, or more important than, withdrawal time for adenoma detection. It is unclear whether a shorter withdrawal time with good technique yields an acceptable lesion detection rate. Our objective was to evaluate a 3-minute versus a 6-minute withdrawal time by using segmental tandem colonoscopy.


    Date de mise en ligne : Lundi 28 novembre 2016
    Shuntaro Mukai, Takayoshi Tsuchiya, Takao Itoi, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Yuichi Nagakawa, Kazuhiko Kasuya, Masaaki Shimatani, Atsushi Sofuni
    Prospective evaluation of a new biflanged metal stent for the treatment of pancreatic fluid collections (with videos)
    EUS-guided transluminal drainage (EUS-TD) and sequential direct endoscopic necrosectomy (DEN) for pancreatic fluid collections (PFCs) by using a dedicated biflanged metal stent (BFMS) has been reported as a useful alternative to using plastic stents or a conventional metal stent. However, current dedicated BFMSs have limitations. Recently, a new BFMS with solidly constructed biflanges and various stent lengths matched to the PFC condition has been developed. Herein, we prospectively evaluated this new BFMS for the treatment of PFCs.


    Date de mise en ligne : Samedi 26 novembre 2016
    Arvind J. Trindade, Sumant Inamdar, Michael S. Smith, Kenneth J. Chang, Cadman L. Leggett, Charles J. Lightdale, Douglas K. Pleskow, Divyesh V. Sejpal, Guillermo J. Tearney, Rebecca M. Thomas, Michael B. Wallace
    Volumetric laser endomicroscopy in Barrett’s esophagus: interobserver agreement for interpretation of Barrett’s esophagus and associated neoplasia among high-frequency users
    Targeting neoplasia in Barrett’s esophagus (BE) is challenging. Volumetric laser endomicroscopy (VLE) is a new imaging technique that allows for real time cross-sectional microstructure imaging that can detect BE neoplasia. The interobserver agreement among users in practice is unknown.


    Date de mise en ligne : Samedi 26 novembre 2016
    Qing-yuan Li, Yan Meng, Yu-yuan Xu, Qiang Zhang, Jian-qun Cai, Hao-xuan Zheng, Hai-tao Qing, Si-lin Huang, Ze-long Han, Ai-min Li, Ying Huang, Ya-li Zhang, Fa-chao Zhi, Rui-jun Cai, Yue Li, Wei Gong, Si-de Liu
    Comparison of endoscopic submucosal tunneling dissection and thoracoscopic enucleation for the treatment of esophageal submucosal tumors
    Endoscopic submucosal tunneling dissection (ESTD) has been proved to be safe and effective for removal of esophageal submucosal tumors (SMTs) and can maintain the mucosal integrity compared with other endoscopic methods. The aim of the study was to estimate the safety and efficacy of ESTD as well as compare its efficacy with thoracoscopic enucleation for esophageal SMTs, which is used increasingly as a minimally invasive approach.


    Date de mise en ligne : Samedi 26 novembre 2016
    Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim, Hyun Kyun Ki
    A randomized controlled trial of prophylactic antibiotics in the prevention of electrocoagulation syndrome after colorectal endoscopic submucosal dissection
    Endoscopic submucosal dissection (ESD) is currently commonly performed, but colorectal ESD has a substantial risk of adverse events, including post-ESD electrocoagulation syndrome (PEECS). We investigated whether the use of prophylactic antibiotics can reduce the occurrence of PEECS.


    Date de mise en ligne : Vendredi 25 novembre 2016
    Dep K. Huynh, Leanne Toscano, Vinh-An Phan, Tsai-Wing Ow, Mark Schoeman, Nam Q. Nguyen
    Ultrathin disposable gastroscope for screening and surveillance of gastroesophageal varices in patients with liver cirrhosis: a prospective comparative study
    This study aims to evaluate the role of unsedated, ultrathin disposable gastroscopy (TDG) against conventional gastroscopy (CG) in the screening and surveillance of gastroesophageal varices (GEVs) in patients with liver cirrhosis.


    Date de mise en ligne : Jeudi 24 novembre 2016
    John M. DeWitt, S. Krishna Murthy, Ramesh Ardhanari, G. Aaron DuVall, Grzegorz Wallner, Paul Litka, Claire Daugherty, Kirk Fowers
    EUS-guided paclitaxel injection as an adjunctive therapy to systemic chemotherapy and concurrent external beam radiation before surgery for localized or locoregional esophageal cancer: a multicenter prospective randomized trial
    OncoGel (Protherics Salt Lake City, Inc, Salt Lake City, UT) is paclitaxel (PTX) formulated in a thermosensitive, biodegradable copolymer for focused cytotoxicity and radiosensitization. A phase 2a study suggested that EUS-guided PTX injection into esophageal tumors subsequently receiving radiotherapy was safe.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Yosuke Toya, Masaki Endo, Shotaro Nakamura, Risaburo Akasaka, Takashi Kosaka, Shunichi Yanai, Keisuke Kawasaki, Keisuke Koeda, Tamotsu Sugai, Takayuki Matsumoto
    Clinical outcomes of non-curative endoscopic submucosal dissection with negative resected margins for gastric cancer
    There has been little information about the long-term outcomes of patients with early gastric cancer (EGC) treated by non-curative endoscopic submucosal dissection (ESD) with negative resected margins (R0 resection). We aimed to compare the clinical outcomes of non-curative ESD with R0 resection between patients who underwent additional gastrectomy and those who did not.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Su Young Kim, Jun-Won Chung, Dong Kyun Park, Kwang An Kwon, Kyoung Oh Kim, Yoon Jae Kim, Jung Ho Kim
    Comparison of carbon dioxide and air insufflation during consecutive EGD and colonoscopy in moderate-sedation patients: a prospective, double-blind, randomized controlled trial
    Endoscopy is performed with air insufflation and is usually associated with abdominal pain. It is well recognized that carbon dioxide (CO2) is absorbed more quickly into the body than air; however, to date, few studies have investigated the use of CO2 insufflation during consecutive EGD and colonoscopy (CEC). Thus, this study evaluated the efficacy of CO2 insufflation compared with air insufflation in CEC.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Jennifer Nayor, John R. Saltzman, Emily J. Campbell, Molly L. Perencevich, Kunal Jajoo, James M. Richter
    Impact of physician compliance with colonoscopy surveillance guidelines on interval colorectal cancer
    Interval colorectal cancer (iCRC) incidence is the criterion standard benchmark for measuring the effectiveness of colonoscopy. Colonoscopy surveillance guidelines are designed to minimize iCRC cases. Our aims were to describe characteristics of iCRC patients and to assess whether development of iCRC is related to colonoscopy surveillance guideline intervals.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Michael J. Bartel, Timothy M. Wallace, Rene D. Gomez-Esquivel, Massimo Raimondo, Herbert C. Wolfsen, Timothy A. Woodward, Michael B. Wallace
    Role of EUS in patients with suspected Barrett’s esophagus with high-grade dysplasia or early esophageal adenocarcinoma: impact on endoscopic therapy
    Endoscopic therapy is the standard treatment for high-grade dysplasia and some cases of T1a esophageal adenocarcinoma (EAC), but it is not appropriate for deeply invasive disease. Data on the value of EUS for patient selection for endoscopic or surgical resection are conflicting. We investigated the outcome of esophageal EUS for the staging and treatment selection of patients with treatment-naive, premalignant Barrett’s esophagus (BE) and suspected superficial EAC.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Michael J. Levy, Steven R. Alberts, William R. Bamlet, Patrick A. Burch, Michael B. Farnell, Ferga C. Gleeson, Michael G. Haddock, Michael L. Kendrick, Ann L. Oberg, Gloria M. Petersen, Naoki Takahashi, Suresh T. Chari
    EUS-guided fine-needle injection of gemcitabine for locally advanced and metastatic pancreatic cancer
    Among the greatest hurdles to pancreatic cancer (PC) therapy is the limited tissue penetration of systemic chemotherapy because of tumor desmoplasia. The primary study aim was to determine the toxicity profile of EUS-guided fine-needle injection (EUS-FNI) with gemcitabine. Secondary endpoints included the ability to disease downstage leading to an R0 resection and overall survival (OS) at 6 months, 12 months, and 5 years after therapy.


    Date de mise en ligne : Mercredi 23 novembre 2016
    Seung Hun Kang, Yoon Tae Jeen, Jae Hyung Lee, In Kyung Yoo, Jae Min Lee, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Hong Sik Lee, Hoon Jai Chun, Chang Duck Kim
    Comparison of a split-dose bowel preparation with 2 liters of polyethylene glycol plus ascorbic acid and 1 liter of polyethylene glycol plus ascorbic acid and bisacodyl before colonoscopy
    Recently, a low-volume polyethylene glycol formulation containing ascorbic acid (PEG-Asc) has proven as safe and effective as traditional 4-L PEG solutions for colonoscopy preparation. However, currently available aqueous purgative formulations are poorly tolerated. The aim of this study was to compare a split-dose 2-L PEG-Asc formulation and a 1-L PEG-Asc formulation with bisacodyl (10 mg) to determine the quality of bowel cleansing and patient tolerability.


    Date de mise en ligne : Mardi 22 novembre 2016
    James W. Walter, William Klump, Francis Spitz, Adam Elfant, Henry C. Ho
    A large degenerated GI stromal tumor presenting as a peripancreatic cyst
    A 21-year-old man presented to the hospital with progressive abdominal distension. On examination, there was a palpable midline mass. CT demonstrated a well-circumscribed, septated, cystic mass in the left upper quadrant, measuring approximately 18 cm (A). EUS demonstrated a normal pancreas with a distinct septated mass (B). FNA yielded 30 mL of amber fluid that demonstrated a paucicellular specimen with proteinaceous debris and rare glandular cells. Fluid chemistry determinations showed carcinoembryonic antigen 0.9 ng/mL and amylase 15 U/L.


    Date de mise en ligne : Samedi 19 novembre 2016
    Huiyun Zhu, Yuanhang Dong, Pei Xie, Zhendong Jin, Yiqi Du
    Cumbersome removal of a lumen-apposing metal stent in a case of refractory pancreatic pseudocyst
    A 32-year-old man with previous severe pancreatitis received a diagnosis of pancreatic pseudocyst and was treated by 3 different methods of drainage. There was no communication between the pseudocyst and the pancreatic duct. The pseudocyst was first discovered 3 years previously (A) and was treated by percutaneous drainage. One year later, in August 2014, the patient presented with abdominal pain and distension again, and EUS showed a huge pseudocyst (15 cm × 15 cm) in the body of the pancreas. We placed a biliary metal stent under the guidance of EUS and removed it 4 months later, but the pseudocyst recurred afterward.


    Date de mise en ligne : Samedi 19 novembre 2016
    Roberto Grassia, Elena Iiritano, Katerina Vjero, Fabrizio Cereatti, Pietro Capone, Federico Buffoli
    Severe acute diverticular bleeding: successful treatment with hemostatic powder
    A 50-year-old man was admitted to the intensive coronary care unit for acute myocardial infarction and was treated by coronary artery stenting and dual antiplatelet therapy. On postprocedure day 5, the patient presented with massive hematochezia, anemia (hemoglobin 10.4 g/dL), and hypovolemic shock. After hemodynamic stabilization, a mesenteric angiogram revealed a left-sided colonic hemorrhage highly suggestive of diverticular bleeding (A, white arrow). Selective embolization was ruled out because of the risk of bowel infarction.


    Date de mise en ligne : Jeudi 17 novembre 2016
    Tarun Rustagi, Shayan Irani, D. Nageshwar Reddy, Barham K. Abu Dayyeh, Todd H. Baron, Christopher J. Gostout, Michael J. Levy, John Martin, Bret T. Petersen, Andrew Ross, Mark D. Topazian
    Radiofrequency ablation for intraductal extension of ampullary neoplasms
    Extension of ampullary adenomas into the common bile duct (CBD) or pancreatic duct (PD) may be difficult to treat endoscopically. We evaluated the feasibility, safety, and efficacy of endoscopic radiofrequency ablation (RFA) in the management of ampullary neoplasms with intraductal extension.


    Date de mise en ligne : Vendredi 11 novembre 2016
    Sundeep Lakhtakia, Jahangeer Basha, Rupjyoti Talukdar, Rajesh Gupta, Zaheer Nabi, Mohan Ramchandani, B.V.N. Kumar, Partha Pal, Rakesh Kalpala, P. Manohar Reddy, R. Pradeep, Jagadish R. Singh, G.V. Rao, D. Nageshwar Reddy
    Endoscopic “step-up approach” using a dedicated biflanged metal stent reduces the need for direct necrosectomy in walled-off necrosis (with videos)
    EUS-guided drainage using plastic stents may be inadequate for treatment of walled-off necrosis (WON). Recent studies report variable outcomes even when using covered metal stents. The aim of this study was to evaluate the efficacy of a dedicated covered biflanged metal stent (BFMS) when adopting an endoscopic “step-up approach” for drainage of symptomatic WON.


    Date de mise en ligne : Jeudi 03 novembre 2016
    Saurabh Sethi, Robert J. Huang, Monique T. Barakat, Niaz Banaei, Shai Friedland, Subhas Banerjee
    Adenosine triphosphate bioluminescence for bacteriologic surveillance and reprocessing strategies for minimizing risk of infection transmission by duodenoscopes
    Recent outbreaks of duodenoscope-transmitted infections underscore the importance of adequate endoscope reprocessing. Adenosine triphosphate (ATP) bioluminescence testing allows rapid evaluation of endoscopes for bacteriologic/biologic residue. In this prospective study we evaluate the utility of ATP in bacteriologic surveillance and the effects of endoscopy staff education and dual cycles of cleaning and high-level disinfection (HLD) on endoscope reprocessing.


    Date de mise en ligne : Mardi 01 novembre 2016
    Vladimir Milivojevic, Ivan Rankovic, Ljiljana Milic, Vasilije Jeremic, Ivan Jovanovic
    Mobile phone in the stomach: call the emergency endoscopist!
    A 39-year-old man presented to the emergency department with profuse melena accompanied by lightheadedness and vertigo. He reported having had 4 black, tarry stools during the past day and acknowledged having taken nonsteroidal anti-inflammatory drugs (NSAIDs) for the past 2 months for abdominal pain. In his personal history, cerebral palsy was present. Clinical and laboratory investigations yielded a Glasgow-Blatchford score of 8. Emergency endoscopy verified large amounts of hematin in his stomach; thus, the patient was referred to the surgical intensive care unit, where he received supportive and pharmacotherapeutic measures.


    Date de mise en ligne : Mardi 01 novembre 2016
    Layth Al-Jashaami, Rashmi Kumar, Rakesh Nanda
    A ribbon in the esophagus
    A 96-year-old man with a history of hypertension and inguinal hernia presented with a “sore throat” of 6 months’ duration, progressively getting worse, associated with a productive yellowish cough and occasional nausea and vomiting, mainly occurring in the evening after eating dinner. He was very active; he walked 4 to 5 miles daily when playing golf 5 days a week and did not use a golf cart! He had quit smoking at age 50 and abstained from alcohol. The results of his physical examination were unremarkable, and laboratory tests showed normal results.


    Date de mise en ligne : Jeudi 20 octobre 2016
    Tarun Rustagi, Ferga C. Gleeson, Suresh T. Chari, Barham K. Abu Dayyeh, Michael B. Farnell, Prasad G. Iyer, Michael L. Kendrick, Randall K. Pearson, Bret T. Petersen, Elizabeth Rajan, Mark D. Topazian, Mark J. Truty, Santhi S. Vege, Kenneth K. Wang, Michael J. Levy
    Remote malignant intravascular thrombi: EUS-guided FNA diagnosis and impact on cancer staging
    Malignant vascular invasion usually results from gross direct infiltration from a primary tumor and impacts cancer staging, prognosis, and therapy. However, patients may also develop a remote malignant thrombi (RMT), defined as a malignant intravascular thrombus located remote and noncontiguous to the primary tumor. Our aim was to compare EUS, CT, and magnetic resonance imaging (MRI) findings of RMT and to explore the potential impact on cancer staging.


    Date de mise en ligne : Samedi 15 octobre 2016
    Amy Tyberg, Stefan Seewald, Reem Z. Sharaiha, Guadalupe Martinez, Amit P. Desai, Nikhil A. Kumta, Arnon Lambroza, Amrita Sethi, Kevin M. Reavis, Ketisha DeRoche, Monica Gaidhane, Michael Talbot, Payal Saxena, Felipe Zamarripa, Maximilien Barret, Nicholas Eleftheriadis, Valerio Balassone, Haruhiro Inoue, Michel Kahaleh
    A multicenter international registry of redo per-oral endoscopic myotomy (POEM) after failed POEM
    Per-oral endoscopic myotomy (POEM) has become an accepted treatment for patients with achalasia. Despite its excellent efficacy rate of greater than 80%, a small percentage of patients remain symptomatic after the procedure. Limited data exist as to the best management for recurrence of symptoms after POEM. We present the first international, multicenter experience on the efficacy and safety of a repeat POEM in the management of achalasia.


    Date de mise en ligne : Samedi 15 octobre 2016
    Shannon Melissa Chan, Anthony Yuen Bun Teoh, Hon Chi Yip, Vivien Wai Yin Wong, Philip Wai Yan Chiu, Enders Kwok Wai Ng
    Feasibility of per-oral cholecystoscopy and advanced gallbladder interventions after EUS-guided gallbladder stenting (with video)
    The recent development of EUS-guided gallbladder drainage (EGBD) with a lumen-apposing stent has made endoscopic assessment and advanced gallbladder interventions via the stent possible. The aim of this study was to assess the feasibility and safety of per-oral cholecystoscopy and the types of gallbladder interventions that can be performed.


    Date de mise en ligne : Jeudi 06 octobre 2016
    Seifeldin Hakim, Tusar Desai, Mitchell S. Cappell
    Esophageal hemangiomatosis with chest CT revealing a fine, curvilinear, calcified thrombus within the esophagus simulating acute esophageal fishbone impaction: first reported endoscopic photograph of GI manifestations in Maffucci syndrome
    A 70-year-old-man with known Maffucci syndrome (confirmed by pathologic analysis of biopsy specimens of enchondromas and hemangiomas), who had undergone resection/amputation of left thumb chondrosarcoma 15 years earlier, without known angina or cardiac disease, presented with sudden onset of substernal chest pain, without dysphagia or vomiting, commencing 1 hour after he had eaten a cooked, whole catfish with bones. Physical examination revealed normal vital signs; normal oropharyngeal, cardiac, and abdominal examination results; and numerous 8-mm to 30-mm-wide nodules, mostly on the left arm and leg, with rare right-sided nodules, consisting of 2 tumor populations: indurated pale enchondromas and soft compressible bluish hemangiomas (A, B, numerous enchondromas and hemangiomas on the [A] dorsal and [B] volar surfaces of the left hand).


    Date de mise en ligne : Jeudi 06 octobre 2016
    Vincent Ganapini, Maryconi Jaurigue, Mitual Amin, Gehad Ghaith, Mitchell S. Cappell
    ERCP for diagnosis and extraction of choledochal phytobezoar causing right upper quadrant abdominal pain and cholestasis in a patient without prior sphincterotomy or biliary instrumentation
    A 72-year-old white man with diabetes mellitus and gastroesophageal reflux, with no history of liver disease, hepatobiliary instrumentation, sphincterotomy, or abdominal trauma, presented with acute right upper quadrant abdominal pain and diaphoresis that had started 1 hour earlier. Physical examination revealed a soft and nontender abdomen. The initial serum liver function test results were all within normal limits but rose acutely to a serum alkaline phosphatase of 224 U/L, aspartate aminotransferase of 355 U/L, alanine aminotransferase of 531 U/L, and total bilirubin of 2.4 mg/dL after 48 hours.


    Date de mise en ligne : Mardi 04 octobre 2016
    Douglas G. Adler
    Esophageal placement of a lumen-apposing metal stent in a patient with a chronic anastomotic stricture
    In 2010, a 59-year-old man experienced adenocarcinoma of the distal esophagus, which involved the periesophageal and mediastinal nodes. He received cisplatin and paclitaxel with radiation. He subsequently underwent transhiatal esophagectomy and has been without evidence of cancer since then. Postoperatively, he experienced a chronic anastomotic stricture with dysphagia and several chronic tracheoesophageal fistulas treated with esophageal and airway stents. In the intervening years, the patient has undergone multiple rounds of esophageal stenting for dysphagia with fully covered stents, but these were removed because he was experiencing coughing, discomfort, and mucous production.


    Date de mise en ligne : Lundi 03 octobre 2016
    Linda Zhang, Paul Edwards, Milan Bassan
    Thoracic osteomyelitis: an unusual adverse event of esophageal stenting
    A 51-year-old man presented with a 3-week history of interscapular pain and night sweats. He had been treated with chemoradiotherapy 15 months earlier for a locally advanced esophageal squamous cell carcinoma 25 cm aboral with complete response on subsequent restaging. A tracheoesophageal fistula (TEF) developed 3 months after chemoradiotherapy 30 cm aboral, initially managed with placement of a 23 mm × 105 mm fully covered esophageal self-expandable metal stent (SEMS) and placement of an overlapping 23 mm × 155 mm fully covered SEMS 6 months later because of stent migration and recurrent aspiration.


    Date de mise en ligne : Vendredi 30 septembre 2016
    Adriana Vaz Safatle-Ribeiro, Elisa Ryoka Baba, Sheila Friedrich Faraj, Juliana Trazzi Rios, Marcelo Simas de Lima, Bruno Costa Martins, Sebastian Naschold Geiger, Caterina Pennacchi, Carla Gusman, FĂĄbio Shiguehissa Kawaguti, Ricardo Sato Uemura, Evandro Sobroza de Melo, Ulysses Ribeiro, Fauze Maluf-Filho
    Diagnostic accuracy of probe-based confocal laser endomicroscopy in Lugol-unstained esophageal superficial lesions of patients with head and neck cancer
    Surveillance programs of patients with head and neck cancer (HNC) detect synchronous or metachronous esophageal squamous cell carcinoma (ESCC) in up to 15% of patients. Noninvasive, probe-based confocal laser endomicroscopy (pCLE) technique may improve the diagnosis allowing acquisition of high-resolution in vivo images at the cellular and microvascular levels. The aim of this study was to evaluate the accuracy of pCLE for the differential diagnosis of nonneoplastic and neoplastic Lugol-unstained esophageal lesions in patients with HNC.


    Date de mise en ligne : Lundi 26 septembre 2016
    Dennis Yang, Roxana M. Coman, Michel Kahaleh, Irving Waxman, Andrew Y. Wang, Amrita Sethi, Ashish R. Shah, Peter V. Draganov
    Endoscopic submucosal dissection for Barrett’s early neoplasia: a multicenter study in the United States
    The role of endoscopic submucosal dissection (ESD) in Barrett’s early neoplasia is not well defined, with most studies originating from Asia and Europe. We aimed to assess the efficacy, safety, and results of ESD in Barrett’s esophagus (BE) with high-grade dysplasia (HGD) and early adenocarcinoma (EAC) across centers in the United States.


    Date de mise en ligne : Samedi 17 septembre 2016
    Kook Hyun Kim, Kathleen McGreevy, Kristin La Fortune, Harvey Cramer, John DeWitt
    Sonographic and cyst fluid cytologic changes after EUS-guided pancreatic cyst ablation
    The effect of EUS-guided pancreatic cyst ablation (PCA) on sonographic morphology and cyst fluid cytology is unknown. The aim of this study was to evaluate morphologic, cytologic, and change in cyst fluid DNA after PCA.


    Date de mise en ligne : Lundi 12 septembre 2016
    Shayan Irani, Sujai Jalaj, Andrew Ross, Michael Larsen, Ian S. Grimm, Todd H. Baron
    Use of a lumen-apposing metal stent to treat GI strictures (with videos)
    Benign GI strictures occur typically in the esophagus and pyloric channel but can occur anywhere in the GI tract and at anastomotic sites. Such strictures can be treated with dilation, incisional therapy, steroid injection, and stents. Our aim was to describe the use of a lumen-apposing metal stent (LAMS) to treat short, benign GI strictures.


    Date de mise en ligne : Mardi 23 août 2016
    Eelco C. Brand, Raouf E. Nakhleh, Michael B. Wallace
    Pseudoinvasion appearing as a deeply invasive malignant colorectal polyp
    A 50-year-old man with alcoholic liver cirrhosis and a Model for End-Stage Liver Disease score of 15 underwent colonoscopy as part of his evaluation and screening for liver transplantation. A malignant-appearing 20-mm sessile polyp with an ulcerated surface, Paris IIa/III, was seen in a tight area of the sigmoid. Owing to notable contractions, the polyp prolapsed into the lumen. The polyp surface, assessed with high-definition near-focus white-light and narrow-band imaging (CF-HQ190, Olympus Corp, Center Valley, Pa), demonstrated a Sano IIIb and Kudo Vn pattern for the ulcer and Sano II for the sharply demarcated margins, suggestive of deep submucosal invasion (A).


    Date de mise en ligne : Lundi 01 août 2016
    Rintaro Hashimoto, Tomoki Matsuda, Hayato Aoki, Toru Okuzono, Masato Nakahori
    Double-balloon assisted trans-anal ERCP in a patient with Roux-en-Y choledochojejunostomy
    A 66-year-old man was referred to our hospital with fever and elevated liver enzymes. His medical history was significant for Roux-en-Y choledochojejunostomy performed because of iatrogenic bile duct injury during cholecystectomy a few years earlier. CT showed biliary tract dilatation and some small liver abscesses. Endoscopic sonography revealed mild dilatation of the common bile duct (CBD). Drip infusion cholecystocholangiography/computed tomography revealed the stenosis at the anastomosis. These results led to a diagnosis of acute cholangitis due to a postoperative CBD stricture.


    Date de mise en ligne : Lundi 01 août 2016
    Yasuyuki Tanaka, Takeharu Nakamura, Shigehiko Fujii, Toshihiro Kusaka
    Successful treatment of a perforated duodenal ulcer with polyglycolic acid sheets
    An 86-year-old woman was admitted to our hospital with severe abdominal and back pain. Abdominal CT revealed a gas-containing retroperitoneal abscess surrounded by the duodenal bulb and anterior part of the right kidney. EGD revealed an active ulcer in the duodenal bulb. Furthermore, a slit-shaped excavation of the ulcer floor (A) and retroperitoneal leakage of contrast medium (B) were detected. Therefore, a perforated duodenal ulcer with a retroperitoneal abscess was diagnosed. The perforation was managed conservatively in consideration of the patient’s poor general condition.


    Date de mise en ligne : Lundi 18 juillet 2016
    Corlan O. Adebajo, Irving Waxman, Christopher Chapman, Carol Semrad
    Foiled by coils: upper GI bleeding from a rare delayed adverse event of transarterial embolization
    A 99-year-old woman was admitted with presyncope and her second GI bleed. One year earlier, she had experienced a major upper-GI bleed from a large cratered duodenal bulb ulcer with a spurting vessel; attempts at endoscopic hemostasis had failed. Angiography revealed a subcentimeter pseudoanuerysm of her gastroduodenal artery (GDA) just caudal to the endoscopic clips. Her GDA was embolized proximal and distal to the pseudoanuerysm with coils extending to the proximal GDA. At her current admission, she was given an intravenous proton pump inhibitor.


    Date de mise en ligne : Vendredi 17 juin 2016
    Jun Fang, Shu-Ling Wang, Hong-Yu Fu, Zhao-Shen Li, Yu Bai
    Impact of gum chewing on the quality of bowel preparation for colonoscopy: an endoscopist-blinded, randomized controlled trial
    Gum chewing can accelerate motility in the GI tract; clinical studies suggested gum chewing can reduce postoperative ileus. However, no trial has investigated the effect of gum chewing on bowel preparation for colonoscopy in addition to polyethylene glycol (PEG). The objective of this study was to investigate whether gum chewing before colonoscopy can increase the quality of bowel preparation.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Information for readers


    Date de mise en ligne : Jeudi 01 janvier 1970
    In upcoming issues...


    Date de mise en ligne : Jeudi 01 janvier 1970
    ASGE update


    Date de mise en ligne : Jeudi 01 janvier 1970
    Focus on...


    Date de mise en ligne : Jeudi 01 janvier 1970
    Editors


    Date de mise en ligne : Jeudi 01 janvier 1970
    Contents


    Date de mise en ligne : Jeudi 01 janvier 1970
    Kenji Hayasaka, Hideaki Harada, Takanori Shimizu, Satoshi Suehiro, Yasushi Katsuyama
    The effectiveness of intraductal ultrasonography for cystic duct cannulation
    A 55-year-old man with angina pectoris and arteriosclerotic obliterans who was receiving dual antiplatelet therapy (aspirin plus cilostazol) was referred to our department because of acute cholecystitis. Because of the risk of bleeding, we first performed ERCP and endoscopic gallbladder stenting instead of an interventional EUS.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Michiko Wada, Motohiko Kato, Yuichiro Hirai, Toshio Uraoka
    Salvage resection of recurrent polyp after polypectomy on the colorectal anastomosis using endoscopic submucosal dissection
    Endoscopic submucosal dissection (ESD) enables secure R0 resection irrespective of size or location of the lesion. However, severe fibrosis is still a condition in which ESD is technically challenging. Here we report a case for which we performed salvage ESD for a recurrent polyp after polypectomy on the colorectal anastomosis.


    Date de mise en ligne : Jeudi 01 janvier 1970
    James Buxbaum, Karthik Ravi, William Ross, Brian Weston, Prasad G. Iyer, Amit Rastogi, Michael B. Wallace
    Continuing Medical Education Exam: June 2017


    Date de mise en ligne : Jeudi 01 janvier 1970
    Erratum
    The name Harry Robert Aslanian, MD, should be part of the author list for the ASGE Report on Emerging Technology, “EUS-guided portal vein interventions” (Gastrointest Endosc 2017;85:883-8).


    Date de mise en ligne : Jeudi 01 janvier 1970
    Monica Saumoy, Michel Kahaleh
    Superiority of metal stents for pancreatic walled-off necrosis: bigger is better!
    The incidence of hospitalizations for acute pancreatitis is rising in the United States.1 Severe cases of pancreatitis, no matter the underlying cause, can lead to the development of pancreatic fluid collections (PFCs).2 Advances in endoscopic tools have driven a new era of minimally invasive techniques to manage both pseudocysts (PCs) and walled-off necrosis (WON). The primarily liquid content of PCs can be easily drained with a single, small-caliber, transmural drain to allow for collapse and resolution.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Robert L. Barclay
    Colonoscopy withdrawal: it takes time to do it well
    “If it were done, when ‘tis done, then ’twere well it were done quickly.”1


    Date de mise en ligne : Jeudi 01 janvier 1970
    Hermann Brenner, Michael Hoffmeister, Christian Stock
    Time to reduce the burden of removing diminutive polyps in colorectal cancer screening
    In their very well conducted systematic review, Vleugels et al1 identified and reviewed studies reporting on the natural history of diminutive (1-5 mm) and small (6-9 mm) colorectal polyps. Based on the limited evidence from the available studies, the estimated progression rates to advanced adenomas or colorectal cancer (CRC) were very low. The results seem to support suggestions that, overall, removal of diminutive and small polyps at screening colonoscopy may do more harm than good because the increased risk of adverse events and increased burden of histologic examinations and surveillance may be too high compared with the expected minimal gain in protection from CRC.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Thomas M. Runge, Phil A. Hart, Elizaburo Sasatomi, Todd H. Baron
    Diagnosis of autoimmune pancreatitis using new, flexible EUS core biopsy needles: report of 2 cases
    We read with interest the article by Kanno et al1 concerning the diagnosis of autoimmune pancreatitis (AIP) by EUS-guided FNA, achieved in 45 of 78 patients, according to the International Consensus Diagnostic Criteria.2 The FNA procedure is not the preferred modality for tissue diagnosis because of the inability to obtain tissue architecture,3 but historically EUS-guided core biopsy specimens have been technically difficult to obtain. In the accompanying editorial,4 it is suggested that newer, more flexible EUS core biopsy needles may become the preferred tissue sampling device.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Douglas J. Robertson, Jeffrey K. Lee
    Response
    We thank Dr Baty1 for his interest in the U.S. Multi-Society Task Force on Colorectal Cancer consensus statement regarding fecal immunochemical test (FIT) use. As noted, we did recommend that anticoagulation and antiplatelet agents not be adjusted to complete a FIT test (strong recommendation, moderate evidence). The recommendation was based on available data examining FIT performance in these circumstances.2,3 Secondarily, it was based on the mechanics of FIT. Hemoglobin is degraded as it moves through the GI tract.


    Date de mise en ligne : Jeudi 01 janvier 1970
    John L. Petrini
    Colonoscopy surveillance intervals: we are not there yet
    If there is a value that physicians hold dear, it is that we provide quality medical care. Our patients trust that we adhere to the current standard of care to protect them from harm and to keep them healthy and free from unnecessary disease as long as possible. Our reputation, livelihood, and professional satisfaction are tightly woven into the provision of care to the highest professional standards that we can achieve. It is the bedrock of our practice, the foundation of patient trust, and the fulfillment of our oath taken at commencement.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Vincent Baty
    Fecal immunochemical testing for colorectal cancer and medication restrictions
    I read with interest the review by Robertson et al1 on the recommendations for fecal immunochemical testing (FIT) to screen for colorectal cancer. The authors noticed that medicine adjustment, including oral anticoagulants or antiplatelet agents, was not required within the screening period.1 This is obviously true for warfarin, aspirin, and nonsteroidal anti-inflammatory drugs. By contrast, one might be more cautious regarding the non–vitamin K antagonist oral anticoagulants (NOACs) because there are no data related to the impact of these molecules on FIT results, whereas they increase the risk of GI bleeding as demonstrated in controlled trials2 but also through postmarketing studies.


    Date de mise en ligne : Jeudi 01 janvier 1970
    Saurabh Chawla, Emad Qayed
    Learning curve for EMR of large nonpolypoid colorectal neoplasia: an alternative analysis method using longitudinal models
    We read with interest the article by Bhurwal et al1 describing the EMR learning curve. The study followed 3 endoscopists and recorded repeated outcome measures with increasing EMR procedure numbers. The authors used graphical evaluation and the test of linear trend to report their findings. We believe that conducting logistic regression and examining the test of trend in this setting is not optimal, given that the observations in the analyzed dataset were not independent but rather were interrelated because they were performed by the same 3 endoscopists over a period of time.